CN104116814A - A traditional Chinese medicine oral liquid for treating jaundice - Google Patents
A traditional Chinese medicine oral liquid for treating jaundice Download PDFInfo
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- CN104116814A CN104116814A CN201410332891.0A CN201410332891A CN104116814A CN 104116814 A CN104116814 A CN 104116814A CN 201410332891 A CN201410332891 A CN 201410332891A CN 104116814 A CN104116814 A CN 104116814A
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- jaundice
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- cudrania
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Abstract
A traditional Chinese medicine oral liquid for treating jaundice is disclosed. The oral liquid mainly comprises following raw materials by weight: 1-3 parts of parasitic tricuspid cudrania root and 1-3 parts of cape jasmine fruit. The oral liquid is prepared by steps of: dipping the parasitic tricuspid cudrania root and the cape jasmine fruit with 3-5 times of water for 30-60 min, heating to 100 DEG C, extracting for 30-60 min, repeating extraction for one time, combining two extraction liquids, filtering to obtain a filtrate, concentrating the filtrate until the relative density at 60 DEG C is 1.10-1.15 to obtain a concentrated liquid, keeping the concentrated liquid for further use, adding water into the concentrated liquid, heating to boil the concentrated liquid, and burdening with each milliliter of the medicine liquid containing 5-10 g of the crude drug. The parasitic tricuspid cudrania root relates to a plant of algarobilla parasitic on the moraceae cudrania plant cudrania cochinchinensis. The oral liquid has functions of protecting the liver, tonifying the gallbladder, lowering the blood pressure, purging intense heat and dispelling dampness, and is used for treating jaundice symptoms caused by function imbalance of the liver and the gallbladder. The Beihai city parasitic loranthus medicine research institute has performed clinical application verification for 120 patients with the jaundice, wherein the 120 patients with the jaundice are treated, the effective rate is 91.7%, local and whole-body side effects are not found during the administration period, and the oral liquid is safe to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of jaundice, belong to medical technical field.
Background technology
Jaundice is because bilirubin metabolism obstacle causes a kind of symptom due to raising of bilirubin concentration in serum and the general name of sign.Clinical manifestation is the xanthochromia of the tissues such as skin, sclera, and when jaundice is deepened, urine, expectorant, tear and perspiration are also by xanthochromia, and digestive tract often has the symptoms such as abdominal distention, stomachache, inappetence, nausea and vomiting, diarrhoea or constipation.The generation reason of jaundice roughly can be divided into: 1, bilirubin generates too much, this be due to erythrocyte by considerable damage (haemolysis) after, unconjugated bilirubin increases, and exceeds the ability of liver in conjunction with unconjugated bilirubin; 2, hepatocyte function is low or have function hepatocyte amount to reduce, and this is due to liver enzyme hypofunction, or liver cirrhosis, acute hepatitis, liver failure cause having the hepatocyte of function to reduce, and can not absorb unconjugated bilirubin; 3, it is excessive that hepatocyte is destroyed conjugated bilirubin, and this is to fail excretion and bile capillary due to conjugated bilirubin, but through downright bad hepatocyte gap anti-inflow in liver lymph fluid and blood; 4, in liver type ChJ and large bile duct block the jaundice causing, this jaundice of two types is all due to the obstruction of bile duct or blocks and cause conjugated bilirubin to overflow from the bile duct breaking, or enters lymph fluid, or enters blood.Jaundice is a kind of symptom sign in other words, and not disease, causes that the reason of jaundice has a lot, but searches to the bottom, mostly relevant with the pathological changes of liver, gallbladder.Diagnosis for jaundice is not so difficult, but Differential Diagnosis is very important, thereby need to be that any reason causes that jaundice imposes treatment targetedly by various routines or specific aim inspection judgement actually.Therefore, can consider from the angle of the traditional Chinese medical science, thereby reach the object for the treatment of jaundice by the Chinese medicinal formulae treatment for liver and gall.
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Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine oral liquid for the treatment of jaundice, for liver and gall diseases treatment eliminate the object of jaundice symptom to reach
The solution of above-mentioned technical problem is to have adopted following technical measures: a kind of Chinese medicine oral liquid for the treatment of jaundice, is mainly made up of following weight parts raw material: the parasitic 1-3 part of Radix Cudraniae, Fructus Gardeniae 1-3 part;
Above-mentioned raw materials is mainly prepared by following method:
(1) get Radix Cudraniae parasitism, Fructus Gardeniae and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 DEG C and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 DEG C of heat survey relative densities, obtains concentrated solution for subsequent use;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product;
Described Radix Cudraniae parasitism, refers to Ceratonia siliqua and colonizes in the plant growing on Moraceae three-bristle cudrania platymiscium cudrania cochinchinensis, and cultural method is:
(1) selecting the Ceratonia siliqua seed of fresh solid health for subsequent use in 10-12 month every year;
(2) get poultry-dung and equal portions cattle manure stirs, be dried to that to present the pasty state fertilizer of viscosity for subsequent use;
(3) a weight portion plant ash is added in 1-3 weight parts water and stirred, after plant ash precipitation, get the supernatant liquid that is sterilized for subsequent use;
(4) sterilized with disinfectant solution in the position of host plant cudrania cochinchinensis sprig bifurcated, then Ceratonia siliqua seed is bonded on the position of host plant cudrania cochinchinensis sprig bifurcated with pasty state fertilizer, the place that is bonded with Ceratonia siliqua seed on cudrania cochinchinensis is wrapped up with dogstail or book film, in 30-60 days, every night, water spray kept moistening, until sprout.
The present invention has adopted Radix Cudraniae parasitism, Fructus Gardeniae to be prepared into oral liquid and has treated the jaundice that liver-gallbladder disease alters.Jaundice is a kind of symptom sign in other words, and not disease, causes that the reason of jaundice has a lot, mostly relevant with the pathological changes of liver, gallbladder.The present invention considers from the angle of traditional Chinese medical science macroscopic view entirety, by treating for liver and gall pathological changes, thereby reaches the object of eliminating jaundice symptom sign.
Radix Cudraniae is often used to treat pulmonary tuberculosis, icterohepatitis, various acute, chronic hepatitis, hepatosplenomegaly, Ceratonia siliqua is colonized in to the Radix Cudraniae parasitism obtaining on Radix Cudraniae and have same effect.Fructus Gardeniae has the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, and modern pharmacology experimental results show that it all has a great impact liver and bile secretion.
Take the present invention of above-mentioned measure, there is hepatoprotective function of gallbladder promoting, blood pressure lowering, the effect of pathogenic fire purging damp eliminating, is used for the treatment of the unbalance jaundice symptom causing of hepato-biliary function.Herba Taxilli institute of materia medica, Beihai has carried out clinical practice checking to 120 routine Patients with Jaundices with the present invention, and checking is reported as follows:
(1) clinical data: get clinical case 120 examples, adult female's 42 examples, adult male 45 examples, not full moon neonate 33, age 0-61 year, course of disease 1-6 days.
(2) Therapeutic Method: oral the present invention, every day is sooner or later each once oral, each oral 10-15mL that is grown up, the each oral 1-3mL of neonate, six days is a course for the treatment of, observes in time local skin and systemic side effects after medication.
(4) observation of curative effect:
(a) criterion of therapeutical effect: after one course for the treatment of of medication.
Cure: clinical symptoms disappears completely, skin, sclera, body fluid xanthochromia disappears, and it is normal that digestive tract function recovers.
Take a turn for the better: clinical symptom relief, sign is improved.
Invalid: clinical symptoms and sign are without any improvement or increase the weight of.
(b) efficacy analysis:
120 routine Icterus treatment effects
| Sick kind | Number of cases | Cure | Take a turn for the better | Invalid |
| Adult male | 45 | 33 | 8 | 4 |
| Adult female | 42 | 30 | 6 | 6 |
| Neonate | 33 | 27 | 6 | 0 |
| Amount to | 120 | 90 | 20 | 10 |
| Effective percentage | ? | 75% | 16.7% | 8.3% |
Side effect is observed: after taking medicine, have no systemic adverse reactions.
(4) conclusion: from above-mentioned Clinical results, the present invention has hepatoprotective function of gallbladder promoting, blood pressure lowering, pathogenic fire purging damp eliminating effect, takes the present invention, treatment Patients with Jaundice 120 examples, obtain good clinical efficacy, effective percentage reaches 91.7%, does not find part and systemic side effects, drug safety during medication.
Detailed description of the invention
Embodiment 1
(1) get Radix Cudraniae parasitism, the each 10kg of Fructus Gardeniae adds 100kg water soaking 60 minutes, be heated to 100 DEG C extract 60 minutes, repeat extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 DEG C of heat survey relative densities, obtains concentrated solution for subsequent use;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain 10 grams of crude drug amounts in every milliliter of medicinal liquid, pack and get final product;
Embodiment 2
(1) get Radix Cudraniae parasitic 10kg, Fructus Gardeniae 30kg and add 120kg water soaking 30 minutes, be heated to 100 DEG C and extract 60 minutes, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 DEG C of heat survey relative densities, obtains concentrated solution for subsequent use;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain 5 grams of crude drug amounts in every milliliter of medicinal liquid, pack and get final product;
Embodiment 3
(1) get Radix Cudraniae parasitic 30kg, Fructus Gardeniae 10kg and add 120kg water soaking 60 minutes, be heated to 100 DEG C and extract 30 minutes, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 DEG C of heat survey relative densities, obtains concentrated solution for subsequent use;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain 10 grams of crude drug amounts in every milliliter of medicinal liquid, pack and get final product.
Claims (1)
1. treat a Chinese medicine oral liquid for jaundice, it is characterized in that described oral liquid is mainly made up of following weight parts raw material: the parasitic 1-3 part of Radix Cudraniae, Fructus Gardeniae 1-3 part;
Above-mentioned raw materials is mainly prepared by following method:
(1) get Radix Cudraniae parasitism, Fructus Gardeniae and add 3-5 times of water gaging to soak 30-60 minute, be heated to 100 DEG C and extract 30-60 minute, repeat to extract once, merging extracted twice liquid filters, obtain filtrate, it is 1.10-1.15 that filtrate is concentrated to 60 DEG C of heat survey relative densities, obtains concentrated solution for subsequent use;
(2) get concentrated solution and add water post-heating to the dosing of boiling, make to contain crude drug amount 5-10 gram in every milliliter of medicinal liquid, pack and get final product;
Described Radix Cudraniae parasitism, refers to Ceratonia siliqua and colonizes in the plant growing on Moraceae three-bristle cudrania platymiscium cudrania cochinchinensis, and cultural method is:
(1) selecting the Ceratonia siliqua seed of fresh solid health for subsequent use in 10-12 month every year;
(2) get poultry-dung and equal portions cattle manure stirs, be dried to that to present the pasty state fertilizer of viscosity for subsequent use;
(3) a weight portion plant ash is added in 1-3 weight parts water and stirred, after plant ash precipitation, get the supernatant liquid that is sterilized for subsequent use;
(4) sterilized with disinfectant solution in the position of host plant cudrania cochinchinensis sprig bifurcated, then Ceratonia siliqua seed is bonded on the position of host plant wampee sprig bifurcated with pasty state fertilizer, the place that is bonded with Ceratonia siliqua seed on wampee is wrapped up with dogstail or book film, in 30-60 days, every night, water spray kept moistening, until sprout.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410332891.0A CN104116814A (en) | 2014-07-14 | 2014-07-14 | A traditional Chinese medicine oral liquid for treating jaundice |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410332891.0A CN104116814A (en) | 2014-07-14 | 2014-07-14 | A traditional Chinese medicine oral liquid for treating jaundice |
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| CN201410332891.0A Pending CN104116814A (en) | 2014-07-14 | 2014-07-14 | A traditional Chinese medicine oral liquid for treating jaundice |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1813984A (en) * | 2005-12-14 | 2006-08-09 | 贵州瑞和制药有限公司 | Chinese medicine preparation for treating liver disease and preparing method |
| CN103720833A (en) * | 2012-10-15 | 2014-04-16 | 戴秀芳 | Traditional Chinese medicine composition used for treating neonatal jaundice |
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2014
- 2014-07-14 CN CN201410332891.0A patent/CN104116814A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1813984A (en) * | 2005-12-14 | 2006-08-09 | 贵州瑞和制药有限公司 | Chinese medicine preparation for treating liver disease and preparing method |
| CN103720833A (en) * | 2012-10-15 | 2014-04-16 | 戴秀芳 | Traditional Chinese medicine composition used for treating neonatal jaundice |
Non-Patent Citations (2)
| Title |
|---|
| 谭支绍: "《药用寄生》", 31 July 1991, 广西科学技术出版社 * |
| 黄燮才: "《肝炎中草药原色图谱》", 31 January 2001, 广西科学技术出版社 * |
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Application publication date: 20141029 |