CN104115866A - Preparation method of medical instrument antiseptic solution - Google Patents
Preparation method of medical instrument antiseptic solution Download PDFInfo
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- CN104115866A CN104115866A CN201310149941.7A CN201310149941A CN104115866A CN 104115866 A CN104115866 A CN 104115866A CN 201310149941 A CN201310149941 A CN 201310149941A CN 104115866 A CN104115866 A CN 104115866A
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- medical instrument
- antiseptic solution
- medical apparatus
- sterilizing liquid
- product
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Abstract
The invention discloses a preparation method of a medical instrument antiseptic solution, and a medical instrument antiseptic solution product belongs to the field of disinfectants; the medical instrument antiseptic solution finished product is prepared from pharmaceutical grade benzalkonium bromide, povidone iodine and a medicinal enhancer as raw materials by mixing at certain temperature. The advantages of the preparation method of the medical instrument antiseptic solution are that: used equipment is less, product production process is simple, investment is low, production is harmless to the human body, the medical instrument antiseptic solution product can full meet medical instrument disinfection needs, can rapid kill a variety of bacteria and virus at normal temperature, and is good in disinfection effect and low in cost.
Description
Technical field
The invention belongs to disinfectant field, relate in particular to a kind of compound method of medical apparatus sterilizing liquid.
Background technology
Medicine equipment needs to carry out cleaning thoroughly after use; it is prevention and control hospital infection that the organic matters such as superincumbent blood, mucus, body fluid are adhered in removal; ensure the important step of medical safety; if it is not clean thorough; any organic matter residual on medicine equipment all can form layer protective layer on the surface of microorganism; the obstruction sterilization factor contacts or postpones its effect with microorganism, thereby hinders disinfection effect.Method for cleaning and disinfecting comprises: the pretreatment before cleaning; Soak the application of liquid; Manual cleaning; The operations such as rust cleaning and lubricating maintenance; The thimerosal that medicine equipment is selected should have fungicidal spectrum wide, nontoxic, odorless, without any corrosive feature.In order to meet above-mentioned requirements, the present invention taking pharmaceutical grade benzalkonium bromide as primary raw material, povidone iodine, medicinal hardening agent produce medical apparatus sterilizing liquid as auxiliary material, pharmaceutical grade benzalkonium bromide is a kind of quaternary ammonium salt cationic surface-active wide-spectrum bactericide, it can change bacterium endochylema membrane permeability, make thalline endochylema extravasation, hinder its metabolism and play killing action, stronger to gram-positive bacteria effect, but to Pseudomonas aeruginosa, acid-fast bacilli and bacterial spore are invalid, can with the rapid combination of protein, meet blood, cotton, cellulose and organic matter exist, effect significantly reduces, in the time of 0.1% following concentration to skin nonirritant, it under normal temperature, is yellow colloid, stable in properties, nonirritant, not damage product, commercially available is the 5% benzalkonium bromide aqueous solution.In order to strengthen the bactericidal effect of thimerosal to Pseudomonas aeruginosa, acid-fast bacilli and bacterial spore, make itself and Betagen Solution composite, Betagen Solution, outward appearance is rufous liquid, bacterium, virus and fungi are all had to good killing action, there is the features such as wide spectrum, efficient, long-acting, nontoxic, non-stimulated, non-corrosiveness, can kill rapidly the pathogenic microorganism such as various virus and bacterium, mycoplasma and gemma, particularly also have powerful killing action to quaternary amine Disinfection Effect is unconspicuous without togavirus, germ.The present invention carries out composite taking pharmaceutical grade benzalkonium bromide, povidone iodine, medicinal hardening agent as raw material, product has advantages of that preparing process is simple, device therefor is few, it is little to invest, the production of product is all harmless with use, can fully meet the needs of medical apparatus sterilizing, can kill rapidly at normal temperatures multiple virus, germ, Disinfection Effect is good and cost is low.
Summary of the invention
The problem that the present invention mainly solves is to provide a kind of compound method of medical apparatus sterilizing liquid, and the method, taking pharmaceutical grade benzalkonium bromide, povidone iodine, medicinal hardening agent as raw material, made finished product afterwards by blending at a certain temperature.The advantage of this production method is: device therefor is few, it is little to invest, production technology is simple, the production of product with use all harmlessly, can kill rapidly at normal temperatures virus, the germ of medical apparatus surface.The weight proportion of the raw material that the present invention uses is: pharmaceutical grade benzalkonium bromide 86%-88%, povidone iodine 10%-12%, medicinal hardening agent 2%.
The present invention can be achieved through the following technical solutions:
A compound method for medical apparatus sterilizing liquid, its feature is made up of following steps:
(1) the pharmaceutical grade benzalkonium bromide of formula ratio is sent into agitator tank, temperature is increased to 15 DEG C-20 DEG C, add while stirring the povidone iodine of formula ratio, stir.
(2) be cooled to normal temperature, add the medicinal hardening agent of formula ratio, after stirring, get product.
(3) using method of this medical apparatus sterilizing liquid is: medicine equipment is directly immersed in to 2-3 hour in medical apparatus sterilizing liquid.
The purity of the pharmaceutical grade benzalkonium bromide described in step (1) is 5%; The purity of povidone iodine is 70%.
The invention has the beneficial effects as follows: the compound method that a kind of medical apparatus sterilizing liquid is provided, the method device therefor is few, production technology simple, it is little to invest, the production of product is all harmless with use, can fully meet the needs of medical apparatus sterilizing, can at normal temperatures multiple virus, the germ of the medical apparatus surface of immersion be killed rapidly, Disinfection Effect is good and cost is low.
Embodiment
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
Be that 86% pharmaceutical grade benzalkonium bromide is sent into agitator tank by accounting for total amount, temperature is increased to 15 DEG C-20 DEG C, add while stirring that to account for total amount be 12% povidone iodine, stir; Be cooled to normal temperature, add that to account for total amount be 2% medicinal hardening agent, after stirring, get product; The using method of this medical apparatus sterilizing liquid is: medicine equipment is directly immersed in to 2-3 hour in medical apparatus sterilizing liquid.
Embodiment 2
Be that 87% pharmaceutical grade benzalkonium bromide is sent into agitator tank by accounting for total amount, temperature is increased to 15 DEG C-20 DEG C, add while stirring that to account for total amount be 11% povidone iodine, stir; Be cooled to normal temperature, add that to account for total amount be 2% medicinal hardening agent, after stirring, get product; The using method of this medical apparatus sterilizing liquid is: medicine equipment is directly immersed in to 2-3 hour in medical apparatus sterilizing liquid.
Embodiment 3
Be that 88% pharmaceutical grade benzalkonium bromide is sent into agitator tank by accounting for total amount, temperature is increased to 15 DEG C-20 DEG C, add while stirring that to account for total amount be 10% povidone iodine, stir; Be cooled to normal temperature, add that to account for total amount be 2% medicinal hardening agent, after stirring, get product; The using method of this medical apparatus sterilizing liquid is: medicine equipment is directly immersed in to 2-3 hour in medical apparatus sterilizing liquid.
Claims (3)
1. a compound method for medical apparatus sterilizing liquid, the raw material weight proportioning of use is: comprise pharmaceutical grade benzalkonium bromide 86%-88%, povidone iodine 10%-12%, medicinal hardening agent 2%; It is characterized in that: step (1) is sent the pharmaceutical grade benzalkonium bromide of formula ratio into agitator tank, temperature is increased to 15 DEG C-20 DEG C, add while stirring the povidone iodine of formula ratio, stir; Step (2) is cooled to normal temperature, adds the medicinal hardening agent of formula ratio, after stirring, gets product.
2. the compound method of a kind of medical apparatus sterilizing liquid as claimed in claim 1, its step (1) is characterised in that: the purity of described pharmaceutical grade benzalkonium bromide is 5%; The purity of povidone iodine is 70%.
3. the using method of this medical apparatus sterilizing liquid is: medicine equipment is directly immersed in to 2-3 hour in medical apparatus sterilizing liquid.
Priority Applications (1)
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CN201310149941.7A CN104115866A (en) | 2013-04-27 | 2013-04-27 | Preparation method of medical instrument antiseptic solution |
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CN201310149941.7A CN104115866A (en) | 2013-04-27 | 2013-04-27 | Preparation method of medical instrument antiseptic solution |
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CN104115866A true CN104115866A (en) | 2014-10-29 |
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CN201310149941.7A Pending CN104115866A (en) | 2013-04-27 | 2013-04-27 | Preparation method of medical instrument antiseptic solution |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106701335A (en) * | 2015-11-14 | 2017-05-24 | 中山市大田汽车护理用品有限公司 | Air conditioning detergent and preparing method thereof |
-
2013
- 2013-04-27 CN CN201310149941.7A patent/CN104115866A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106701335A (en) * | 2015-11-14 | 2017-05-24 | 中山市大田汽车护理用品有限公司 | Air conditioning detergent and preparing method thereof |
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Application publication date: 20141029 |