CN104114191A - 心肌灌注显像造影剂 - Google Patents

心肌灌注显像造影剂 Download PDF

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Publication number
CN104114191A
CN104114191A CN201280069796.5A CN201280069796A CN104114191A CN 104114191 A CN104114191 A CN 104114191A CN 201280069796 A CN201280069796 A CN 201280069796A CN 104114191 A CN104114191 A CN 104114191A
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CN
China
Prior art keywords
developer
compound
patient
acid
isotope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280069796.5A
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English (en)
Chinese (zh)
Inventor
马丁·约翰森
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Respiratorius AB
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Respiratorius AB
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Filing date
Publication date
Application filed by Respiratorius AB filed Critical Respiratorius AB
Publication of CN104114191A publication Critical patent/CN104114191A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN201280069796.5A 2011-12-22 2012-12-18 心肌灌注显像造影剂 Pending CN104114191A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161579113P 2011-12-22 2011-12-22
SE1151249-8 2011-12-22
SE1151249 2011-12-22
US61/579,113 2011-12-22
PCT/SE2012/051421 WO2013095273A1 (en) 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion

Publications (1)

Publication Number Publication Date
CN104114191A true CN104114191A (zh) 2014-10-22

Family

ID=48668967

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280069796.5A Pending CN104114191A (zh) 2011-12-22 2012-12-18 心肌灌注显像造影剂

Country Status (15)

Country Link
US (2) US9295738B2 (https=)
EP (1) EP2793952B1 (https=)
JP (1) JP6140187B2 (https=)
KR (1) KR101931792B1 (https=)
CN (1) CN104114191A (https=)
AU (1) AU2012354223B2 (https=)
BR (1) BR112014015124A2 (https=)
CA (1) CA2859773C (https=)
ES (1) ES2687234T3 (https=)
IL (1) IL233219A (https=)
MX (1) MX356258B (https=)
RU (1) RU2629840C2 (https=)
SG (1) SG11201403429YA (https=)
WO (1) WO2013095273A1 (https=)
ZA (1) ZA201405199B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107233585A (zh) * 2017-06-09 2017-10-10 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955876B2 (en) * 2016-09-08 2018-05-01 Raul Chirife Device and method for assessment of left ventricular ejection fraction and other parameters of cardiac performance
CN114832118B (zh) * 2022-07-04 2022-09-27 北京先通国际医药科技股份有限公司 化合物i液体组合物、制备方法及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021858A2 (en) * 2005-08-10 2007-02-22 Bristol-Myers Squibb Pharma Company Methods of making radiolabeled tracers and precursors thereof
CN1925878A (zh) * 2004-02-13 2007-03-07 布里斯托尔-迈尔斯·斯奎布制药公司 供心肌灌注成像所用的对比剂
WO2010097410A1 (en) * 2009-02-24 2010-09-02 Respiratorius Ab Novel bronchodilating diazaheteroaryls

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005033079A1 (ja) 2003-09-30 2005-04-14 Eisai Co., Ltd. ヘテロ環化合物を含有する新規な抗真菌剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1925878A (zh) * 2004-02-13 2007-03-07 布里斯托尔-迈尔斯·斯奎布制药公司 供心肌灌注成像所用的对比剂
WO2007021858A2 (en) * 2005-08-10 2007-02-22 Bristol-Myers Squibb Pharma Company Methods of making radiolabeled tracers and precursors thereof
WO2010097410A1 (en) * 2009-02-24 2010-09-02 Respiratorius Ab Novel bronchodilating diazaheteroaryls

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
魏敏吉 等主编: "同位素示踪技术在创新药物药代动力学研究中的应用", 《创新药物药代动力学研究与评价》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107233585A (zh) * 2017-06-09 2017-10-10 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途
CN107233585B (zh) * 2017-06-09 2021-01-22 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Also Published As

Publication number Publication date
EP2793952B1 (en) 2018-06-13
US9687565B2 (en) 2017-06-27
HK1201459A1 (en) 2015-09-04
ZA201405199B (en) 2015-12-23
JP6140187B2 (ja) 2017-05-31
KR101931792B1 (ko) 2019-03-13
MX2014007491A (es) 2015-02-17
JP2015500873A (ja) 2015-01-08
BR112014015124A2 (pt) 2017-06-13
ES2687234T3 (es) 2018-10-24
CA2859773A1 (en) 2013-06-27
CA2859773C (en) 2020-09-01
RU2014125849A (ru) 2016-02-10
AU2012354223B2 (en) 2017-03-16
RU2629840C2 (ru) 2017-09-04
MX356258B (es) 2018-05-16
IL233219A0 (en) 2014-08-31
EP2793952A1 (en) 2014-10-29
US20160101195A1 (en) 2016-04-14
IL233219A (en) 2016-08-31
AU2012354223A1 (en) 2014-07-03
US9295738B2 (en) 2016-03-29
SG11201403429YA (en) 2014-07-30
US20140341808A1 (en) 2014-11-20
EP2793952A4 (en) 2015-09-09
WO2013095273A1 (en) 2013-06-27
KR20140107411A (ko) 2014-09-04

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Application publication date: 20141022

RJ01 Rejection of invention patent application after publication