CN104114165B - 用于治疗憩室病的方法和组合物 - Google Patents

用于治疗憩室病的方法和组合物 Download PDF

Info

Publication number
CN104114165B
CN104114165B CN201280062802.4A CN201280062802A CN104114165B CN 104114165 B CN104114165 B CN 104114165B CN 201280062802 A CN201280062802 A CN 201280062802A CN 104114165 B CN104114165 B CN 104114165B
Authority
CN
China
Prior art keywords
glutamine
salt
compositions
glutaminate
diverticular disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201280062802.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN104114165A (zh
Inventor
新原丰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emmaus Medical Inc
Original Assignee
Emmaus Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emmaus Medical Inc filed Critical Emmaus Medical Inc
Publication of CN104114165A publication Critical patent/CN104114165A/zh
Application granted granted Critical
Publication of CN104114165B publication Critical patent/CN104114165B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/24—Cellulose or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201280062802.4A 2011-12-19 2012-12-14 用于治疗憩室病的方法和组合物 Active CN104114165B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161630831P 2011-12-19 2011-12-19
US61/630,831 2011-12-19
PCT/US2012/000576 WO2013095681A1 (en) 2011-12-19 2012-12-14 Methods and compositions for the treatment of diverticulosis

Publications (2)

Publication Number Publication Date
CN104114165A CN104114165A (zh) 2014-10-22
CN104114165B true CN104114165B (zh) 2016-10-19

Family

ID=48669319

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280062802.4A Active CN104114165B (zh) 2011-12-19 2012-12-14 用于治疗憩室病的方法和组合物

Country Status (13)

Country Link
US (4) US9616041B2 (OSRAM)
EP (2) EP3603631B1 (OSRAM)
JP (1) JP6060176B2 (OSRAM)
KR (4) KR101848722B1 (OSRAM)
CN (1) CN104114165B (OSRAM)
AU (1) AU2012355956B2 (OSRAM)
BR (1) BR112014014765A8 (OSRAM)
DK (1) DK2793875T3 (OSRAM)
ES (1) ES2770585T3 (OSRAM)
IN (1) IN2014KN01255A (OSRAM)
MX (1) MX351688B (OSRAM)
RU (2) RU2733396C2 (OSRAM)
WO (1) WO2013095681A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2733396C2 (ru) * 2011-12-19 2020-10-01 Иммаус Медикал, Инк. Способы и композиции для лечения дивертикулеза
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
EP3790545A4 (en) * 2019-07-17 2021-07-28 Emmaus Medical, Inc. METHODS AND COMPOSITIONS FOR TREATMENT OF SICKLE CLEANEMIA AND THALASSEMIA
US20230053227A1 (en) * 2021-07-27 2023-02-16 G&S Laboratories, Inc. Dietary fiber compositions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005304A1 (en) * 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
CN1953769A (zh) * 2004-03-17 2007-04-25 自动健康有限公司 膳食添加剂及治疗消化系统相关病症的方法
US20080003265A1 (en) * 2006-06-28 2008-01-03 John Francis Casey Protein and fiber containing dietary supplement

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2196053T3 (es) * 1994-01-11 2003-12-16 Stichting Zofia Procedimiento para el tratamiento de trastornos del cuerpo humano o animal mediante la administracion de aminoacidos.
JP2000060487A (ja) * 1998-08-27 2000-02-29 Kao Corp 便秘改善剤
US7030092B1 (en) * 2001-08-24 2006-04-18 Small Giant L.L.C. Ultra-high fiber supplement and method of reducing weight cardiovascular risks and ingested toxins.
US20050058671A1 (en) 2003-05-09 2005-03-17 Bedding Peter M.J. Dietary supplement and method for treating digestive system-related disorders
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
EP2561766B1 (en) * 2006-11-07 2018-01-17 The Procter and Gamble Company Fiber containing compositions and methods of making and using same
RU2454730C1 (ru) * 2011-03-15 2012-06-27 Александр Михайлович Пузиков Способ лечения дивертикулеза в эксперименте
RU2733396C2 (ru) * 2011-12-19 2020-10-01 Иммаус Медикал, Инк. Способы и композиции для лечения дивертикулеза

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005304A1 (en) * 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
CN1953769A (zh) * 2004-03-17 2007-04-25 自动健康有限公司 膳食添加剂及治疗消化系统相关病症的方法
US20080003265A1 (en) * 2006-06-28 2008-01-03 John Francis Casey Protein and fiber containing dietary supplement

Also Published As

Publication number Publication date
RU2014123433A (ru) 2016-02-10
RU2733396C2 (ru) 2020-10-01
EP3603631A1 (en) 2020-02-05
MX351688B (es) 2017-10-25
US10258586B2 (en) 2019-04-16
WO2013095681A1 (en) 2013-06-27
EP2793875A1 (en) 2014-10-29
EP3603631B1 (en) 2023-11-29
US20190201361A1 (en) 2019-07-04
KR20170038111A (ko) 2017-04-05
KR20140103281A (ko) 2014-08-26
RU2662917C2 (ru) 2018-07-31
EP2793875B1 (en) 2020-02-05
AU2012355956B2 (en) 2016-07-21
BR112014014765A8 (pt) 2017-07-04
EP3603631C0 (en) 2023-11-29
AU2012355956A1 (en) 2014-07-03
US20130178531A1 (en) 2013-07-11
US9616041B2 (en) 2017-04-11
EP2793875A4 (en) 2015-06-03
JP2015500340A (ja) 2015-01-05
BR112014014765A2 (pt) 2017-06-13
KR20170087531A (ko) 2017-07-28
MX2014007382A (es) 2014-09-22
US20170157080A1 (en) 2017-06-08
CN104114165A (zh) 2014-10-22
JP6060176B2 (ja) 2017-01-11
RU2018126834A3 (OSRAM) 2019-04-25
US11304918B2 (en) 2022-04-19
DK2793875T3 (da) 2020-02-24
IN2014KN01255A (en) 2015-10-16
US20220202758A1 (en) 2022-06-30
KR101848722B1 (ko) 2018-04-13
ES2770585T3 (es) 2020-07-02
KR20180039187A (ko) 2018-04-17
RU2018126834A (ru) 2019-03-14

Similar Documents

Publication Publication Date Title
US20220202758A1 (en) Methods and compositions for the treatment of diverticulosis
US20160166631A1 (en) Nutraceutical combination for prevention and treatment of type 2 diabetes
IL167389A (en) Leucine-enriched nutritional compositions
US12156886B2 (en) Methods of increasing blood oxygen saturation
JPS62501845A (ja) 制御放出塩化カリウム
WO2012080831A1 (en) Composition for the treatment of metabolic disorders
WO2019220335A1 (en) Compositions for use in the treatment of obesity
HK1257401A1 (zh) 用於治疗糖尿病和相关病症的方法和组合物
US20110117070A1 (en) Compositions and methods for treating headache
Bołtuć et al. Focal segmental glomerulosclerosis as a rare side effect of combined anabolic-androgenic steroid use, high-protein diet and high-intensity anaerobic training
EP2537528B1 (en) Pharmaceutical compositions containing beta- and alpha-galactosidase and their use in the treatment of gastroesophageal reflux disease
US12251400B2 (en) Liquid concentrates of calcium and magnesium
JP2022519320A (ja) 便秘および胃腸系の他の疾患の治療のための組成物および方法
Liza Impact of Different Supplement Drugs on the Dissolution Profile of Zantac and Xantid
Bołtuć et al. Polish Annals of Medicine
WO2007026742A1 (ja) 大腸デリバリー型炎症性大腸疾患治療薬
TW201733572A (zh) 用於預防及治療第2型糖尿病之營養品組合

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant