CN104107368A - Traditional Chinese medicinal formula and preparation method thereof - Google Patents

Traditional Chinese medicinal formula and preparation method thereof Download PDF

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Publication number
CN104107368A
CN104107368A CN201410365892.5A CN201410365892A CN104107368A CN 104107368 A CN104107368 A CN 104107368A CN 201410365892 A CN201410365892 A CN 201410365892A CN 104107368 A CN104107368 A CN 104107368A
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raw material
pill
parts
thick paste
chinese medicine
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CN201410365892.5A
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侯明岳
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Abstract

The invention relates to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicinal formula and a preparation method thereof. The traditional Chinese medicinal formula comprises the following raw materials in parts by mass: 1-3 parts of radix zanthoxyli, 1-3 parts of heterosmilax japonica, 1-3 parts of Japanese yam, 1-3 parts of ficus pumila, 1-2 parts of cibotium barometz, 1-2 parts of rhizoma drynariae, 1-2 parts of radix clematidis and 1-2 parts of liquorice. The traditional Chinese medicinal formula can be used for curing rheumatic lumbocrural pain, lumbar muscle strain, scapulohumeral periarthritis and other rheumatoid and joint pains, has a remarkable curative effect, can be used for treating both symptoms and root causes and preventing relapse after patients are cured, is easily available in raw materials and convenient to take, and has a relatively short treatment cycle, low cost and good comprehensive effect.

Description

A kind of Chinese medicine formula and preparation method thereof
Technical field
The present invention relates to tcm field, in particular to a kind of Chinese medicine formula and preparation method thereof.
Background technology
Because social competition is day by day fierce now, people's rhythm of life is accelerated, stress strengthens, add going from bad to worse of environment, the rheumatoids such as rheumatic lumbago and skelalgia, lumbar muscle strain, scapulohumeral periarthritis and arthralgia disease belong to people's common frdquently encountered disease, once and must on be difficult to root, can only rely on the simple and easy conventional ways such as massage treatment, the remorse treatment of pin, closed treating, functional exercise to slow down the state of an illness, especially slight patient is had to very fast good therapeutic effect, but not effectively real to severe patient, often the initial stage takes effect, but cures the symptoms, not the disease, easily recurrence.
For a long time, the method that people find rheumatoids such as can curing rheumatic lumbago and skelalgia, lumbar muscle strain, scapulohumeral periarthritis and arthralgia disease always occurs, and can also no longer recur after curing.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine formula and preparation method thereof, to solve the above problems.
A kind of Chinese medicine formula is provided in an embodiment of the present invention, and its raw material comprises following component by mass fraction: Radix Zanthoxyli 1-3 part, golden steel toe 1-3 part, Rhizoma Dioscoreae Nipponicae 1-3 part, Xue Li 1-3 part, Rhizoma Cibotii 1-2 part, Rhizoma Drynariae 1-2 part, Radix Clematidis 1-2 part, Radix Glycyrrhizae 1-2 part.
Preferably, its raw material comprises following component by mass fraction: Radix Zanthoxyli 1-2 part, golden steel toe 1-2 part, Rhizoma Dioscoreae Nipponicae 1-2 part, Xue Li 1-2 part, Rhizoma Cibotii 1-1.5 part, Rhizoma Drynariae 1-1.5 part, Radix Clematidis 1-1.5 part, Radix Glycyrrhizae 1-1.5 part.
The Chinese medicine formula that the embodiment of the present invention provides, can cure the rheumatoids such as rheumatic lumbago and skelalgia, lumbar muscle strain, scapulohumeral periarthritis and arthralgia sick, its evident in efficacy and treating both the principal and secondary aspects of a disease, once curing, can not recur, and raw material is easily got, taking convenience, treatment cycle is short relatively, cost is low, and resultant effect is good.
The embodiment of the present invention also provides a kind of preparation method of Chinese medicine formula, comprises the steps:
(A) take described raw material, get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of described powder is 80-100 order;
(B) by 3/5ths of remaining gross mass in described raw material, be soaked in water, heating decocts, filtering and concentrating obtains thick paste;
(C) get 1/5th the described powder that accounts for gross mass in raw material and 2/5ths the described thick paste mixing and stirring that accounts for gross mass in raw material, make pill, and on the described pill surface of making, sprinkle again a certain amount of described thick paste and remaining described powder after measuring ball weight;
(D) pill through above-mentioned steps is dried, selects, with remaining described thick paste, carries out obtaining finished product after pill surface lubrication polishing and dry in the sun.
By raw material is made respectively to thick paste and powder, and then be mixed and made into the mode of pill, ingredients in raw material interpenetrated and merge, give full play to the actual drug effect of every taste medical material, make its comprehensive drug more remarkable.
(C) a certain amount of thick paste that spreads use on pill surface in step is in 1/5th thick pastes of remaining gross mass, to get after some sprinkle, also will remain some thick pastes and in (D) step, carry out pill use when lubricated, remaining powder is used up in (C) step.
Preferably, the concrete steps of described step (B) are: by 3/5ths use quality of remaining gross mass in described raw material, be its 8-10 water soaking 1-2h doubly, heating decocts 2-4 time, each 1-2h, merging filtrate, is then concentrated into the thick paste that the density with respect to water is 1.35-1.40.When preparing thick paste, to first medical material fully be flooded so that medical material fully expands to the active component that is conducive to medical material inside abundant stripping when decocting, and then decocting and concentrating repeatedly, in the thick paste finally obtaining, the effective content of active component is high, has greatly improved the drug effect of the pill of preparation.
Preferably, in described step (C), be taken as gross mass in 1/5th described powder of gross mass in raw material and raw material 2/5ths described in add ethanol during thick paste mixing and stirring, mixing speed is 200-300rad/min, under room temperature, stir 2-3h, fully stir so that powder mixes with thick paste the fusion of interpenetrating fully.
Preferably, in described step (D), the concrete steps of pill when dry are: pill is placed in to baking oven and is dried, temperature is controlled at 65-80 ℃, be dried to the mass fraction of pill water content below 6%, the too high meeting of water content in pill has influence on the drug effect of itself, and standing time of a specified duration can be more apt to deteriorate.
Preferably, in described step (D), the concrete steps of pill surface lubrication polishing are: with described thick paste and lubricant, repeatedly cover behind pill surface 2-3 time again with insect wax or the polishing of silicone oil wax, for prevent pill bonded to each other with between pill together with, not corrupt for pill is better guaranteed the quality yet, on its surface, repeatedly cover and polishing operation.
Preferably, in described step (D), the time that pill dry in the sun is placed, between 12-24h, is played sterilization, the further effect of pill drying through last dry in the sun.
The specific embodiment
Below by specific embodiment, the present invention is described in further detail.
Embodiment 1
The preparation method of Chinese medicine formula is as follows:
(A) take raw material, Radix Zanthoxyli 10kg, golden steel toe 10kg, Rhizoma Dioscoreae Nipponicae 10kg, Xue Li 10kg, Rhizoma Cibotii 10kg, Rhizoma Drynariae 10kg, Radix Clematidis 10kg, Radix Glycyrrhizae 10kg;
Get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of described powder is 80 orders;
(B) by 3/5ths of remaining gross mass in raw material, be soaked in water, heating decocts, filtering and concentrating obtains thick paste;
(C) get 1/5th the powder that accounts for gross mass in raw material and 2/5ths the thick paste mixing and stirring that accounts for gross mass in raw material, make pill, and measure ball and on the pill surface of making, sprinkle again a certain amount of thick paste and remaining powder after heavy;
(D) pill through above-mentioned steps is dried, selects, with remaining thick paste, carries out obtaining finished product after pill surface lubrication polishing and dry in the sun.
Embodiment 2
The preparation method of Chinese medicine formula is as follows:
(A) take raw material, Radix Zanthoxyli 30kg, golden steel toe 30kg, Rhizoma Dioscoreae Nipponicae 30kg, Xue Li 30kg, Rhizoma Cibotii 20kg, Rhizoma Drynariae 20kg, Radix Clematidis 20kg, Radix Glycyrrhizae 20kg;
Get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of powder is 100 orders;
(B) by 3/5ths use quality of remaining gross mass in raw material, be its water soaking 1h of 8 times, heating decocts 2 each 1h, merge the filtrate of twice is concentrated into the thick paste that the density with respect to water is 1.35;
(C) get 1/5th the powder that accounts for gross mass in raw material and account for 2/5ths thick paste mixing and stirring of gross mass in raw material and add ethanol better to make drug effect merge, mixing speed is 200rad/min, under room temperature, stir 2h, make pill, and on the pill surface of making, sprinkle again a certain amount of thick paste and remaining powder after measuring ball weight;
(D) the pill baking temperature through above-mentioned steps is controlled to 65 ℃, be dried to the mass fraction of pill water content 5%, select away fine powder, piller, lopsided ball etc., with remaining thick paste, carry out pill surface and repeatedly then after polishing and dry in the sun, obtain finished product lubricated 2 times.
Embodiment 3
The preparation method of Chinese medicine formula is as follows:
(A) take raw material, Radix Zanthoxyli 20kg, golden steel toe 20kg, Rhizoma Dioscoreae Nipponicae 30kg, Xue Li 20kg, Rhizoma Cibotii 15kg, Rhizoma Drynariae 15kg, Radix Clematidis 15kg, Radix Glycyrrhizae 15kg;
Get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of powder is 90 orders;
(B) by 3/5ths use quality of remaining gross mass in raw material, be its water soaking 2h of 9 times, heating decocts 4 each 2h, merge each filtrate is concentrated into the thick paste that the density with respect to water is 1.40;
(C) get 1/5th the powder that accounts for gross mass in raw material and account for 2/5ths thick paste mixing and stirring of gross mass in raw material and add ethanol better to make drug effect merge, mixing speed is 300rad/min, under room temperature, stir 3h, make pill, and on the pill surface of making, sprinkle again a certain amount of thick paste and remaining powder after measuring ball weight;
(D) the pill baking temperature through above-mentioned steps is controlled to 80 ℃, be dried to the mass fraction of pill water content 4%, select away fine powder, piller, lopsided ball etc., with remaining thick paste and lubricant, carry out pill surface and repeatedly then with insect wax polishing and dry in the sun 12h, obtain finished product afterwards lubricated 3 times.
Embodiment 4
The preparation method of Chinese medicine formula is as follows:
(A) take raw material, Radix Zanthoxyli 20kg, golden steel toe 20kg, Rhizoma Dioscoreae Nipponicae 30kg, Xue Li 20kg, Rhizoma Cibotii 15kg, Rhizoma Drynariae 15kg, Radix Clematidis 15kg, Radix Glycyrrhizae 15kg;
Get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of powder is 100 orders;
(B) by 3/5ths use quality of remaining gross mass in raw material, be its water soaking 2h of 9 times, heating decocts 3 each 1h, merge each filtrate is concentrated into the thick paste that the density with respect to water is 1.38;
(C) get 1/5th the powder that accounts for gross mass in raw material and account for 2/5ths thick paste mixing and stirring of gross mass in raw material and add ethanol better to make drug effect merge, mixing speed is 250rad/min, under room temperature, stir 3h, make pill, and on the pill surface of making, sprinkle again a certain amount of thick paste and remaining powder after measuring ball weight;
(D) the pill baking temperature through above-mentioned steps is controlled to 70 ℃, be dried to the mass fraction of pill water content 5%, select away fine powder, piller, lopsided ball etc., with remaining thick paste and Pulvis Talci, carry out pill surface and repeatedly then with the polishing of silicone oil wax and dry in the sun 24h, obtain finished product afterwards lubricated 2 times.
With the Chinese medicine of above-mentioned preparation, carry out clinical experiment:
Case history 1: Wu (female) 55 years old
The state of an illness: suffer from for many years rheumatic lumbago and skelalgia, especially overcast and rainy easy outbreak after suffering from the time of 40 years old, hurt like hell after outbreak, can not dry weight live, carry out traditional Chinese massage always, generally to massage once in a week, seriously after three or five days, go to massage once, but can only play the effect of alleviation, can not cure.Treatment: every day, pills was three times, each 10g of morning, noon and afternoon, massage is carried out auxiliary treatment and is not stopped, and after 15 days, feels that shank joint easily, does not have very strong pain, after 30 days, the treatment of massage mate-assist stops, and pain does not have substantially, only after dry too much taskwork, just can feel shank pain, until after taking medicine 3 months, waist and leg pains is cured, and can not recur, and not be afraid of now dry weight and live, walk that shank can not felt to ache, all are normal for mental attitude yet.
Case history 2: father-in-law (man) 32 years old
The state of an illness: due to the computer work of often bending over the desk, suffer from scapulohumeral periarthritis, but massage is sticked on the plaster treatment darg shoulder cervical vertebra place hurt like hell that gets off always, especially blows for a long time air-conditioning summer in office, when serious, arm can not lifted at all.Treatment: take Chinese medicinal pill every day twice, each 10g of morning and evening, feel after 15 days shoulder easily, with hands, press not can pain miserable, after 30 days, scapulohumeral periarthritis is cured, and can not recur, but work will walk about for 1 hour in the time of will noting usually working, alleviates, and note warmingly, can not catch a cold.
Experimental example 1
Randomly draw and suffer from rheumatic lumbago and skelalgia, lumbar muscle strain, 200 of the patients of the rheumatoids such as scapulohumeral periarthritis and arthralgia disease, age is in 30-85 year, men and women does not limit, be divided into 4 groups, every group 50, the people of first group takes the Chinese medicinal pill of embodiment 1, the people of second group takes the pill of embodiment 2, the people of the 3rd group takes the Chinese medicinal pill of embodiment 3, the people of the 4th group takes the Chinese medicinal pill of embodiment 4, instructions of taking is: respectively take after meal 10g sooner or later, adhere to three months, during this, need not coordinate other auxiliary treatment such as massage and sealing, after three months, to participating in the people of statistical experiment, investigate, survey result is as following table 1:
Table 1 survey result
Concrete evaluation criterion is as follows:
Cure: joint is painless, can carry out normal physical work;
Effect is remarkable: when dry weight is lived once in a while or wind-engaging also can feels pain, but the state of an illness is clearly better;
Without positive effect: not feeling has any improvement;
As can be seen from Table 1, after having taken the Chinese medicine of the embodiment of the present invention, arthralgia patient's curative effect is remarkable, and person's state of an illness is slightly not heavy with there is no positive effect wherein there is no healing, needs just can take effect the course for the treatment of of longer time.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (8)

1. a Chinese medicine formula, is characterized in that, its raw material comprises following component by mass fraction: Radix Zanthoxyli 1-3 part, golden steel toe 1-3 part, Rhizoma Dioscoreae Nipponicae 1-3 part, Xue Li 1-3 part, Rhizoma Cibotii 1-2 part, Rhizoma Drynariae 1-2 part, Radix Clematidis 1-2 part, Radix Glycyrrhizae 1-2 part.
2. a kind of Chinese medicine formula according to claim 1, it is characterized in that, its raw material comprises following component by mass fraction: Radix Zanthoxyli 1-2 part, gold steel toe 1-2 part, Rhizoma Dioscoreae Nipponicae 1-2 part, Xue Li 1-2 part, Rhizoma Cibotii 1-1.5 part, Rhizoma Drynariae 1-1.5 part, Radix Clematidis 1-1.5 part, Radix Glycyrrhizae 1-1.5 part.
3. the preparation method of the Chinese medicine formula described in claim 1-2 any one, is characterized in that, comprises the steps:
(A) take described raw material, get 2/5ths of gross mass in raw material and be crushed to powder, the order granularity of described powder is 80-100 order;
(B) by 3/5ths of remaining gross mass in described raw material, be soaked in water, heating decocts, filtering and concentrating obtains thick paste;
(C) get 1/5th the described powder that accounts for gross mass in raw material and 2/5ths the described thick paste mixing and stirring that accounts for gross mass in raw material, make pill, and on the described pill surface of making, sprinkle again a certain amount of described thick paste and remaining described powder after measuring ball weight;
(D) pill through above-mentioned steps is dried, selects, with remaining described thick paste, carries out obtaining finished product after pill surface lubrication polishing and dry in the sun.
4. the preparation method of Chinese medicine formula according to claim 3, it is characterized in that, the concrete steps of described step (B) are: by 3/5ths use quality of remaining gross mass in described raw material, be its 8-10 water soaking 1-2h doubly, heating decocts 2-4 time, each 1-2h, merging filtrate, is then concentrated into the thick paste that the density with respect to water is 1.35-1.40.
5. the preparation method of Chinese medicine formula according to claim 3, it is characterized in that, in described step (C), be taken as gross mass in 1/5th described powder of gross mass in raw material and raw material 2/5ths described in add ethanol during thick paste mixing and stirring, mixing speed is 200-300rad/min, under room temperature, stirs 2-3h.
6. the preparation method of Chinese medicine formula according to claim 3, it is characterized in that, in described step (D), the concrete steps of pill when dry are: pill is placed in to baking oven and is dried, temperature is controlled at 65-80 ℃, is dried to the mass fraction of pill water content below 6%.
7. the preparation method of Chinese medicine formula according to claim 3, it is characterized in that, in described step (D), the concrete steps of pill surface lubrication polishing are: with described thick paste and lubricant, repeatedly cover behind pill surface 2-3 time again with insect wax or the polishing of silicone oil wax.
8. the preparation method of Chinese medicine formula according to claim 3, is characterized in that, in described step (D), the time that pill dry in the sun is placed is between 12-24h.
CN201410365892.5A 2014-07-29 2014-07-29 Traditional Chinese medicinal formula and preparation method thereof Pending CN104107368A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105477214A (en) * 2015-12-22 2016-04-13 青岛海之星生物科技有限公司 Spray for treating scapulohumeral periarthritis and preparation method thereof
CN107998246A (en) * 2018-01-18 2018-05-08 上海市普陀区人民医院 It is a kind of treat traumatic injury caused by chronic soft tissue injury or osteoarthrosis pain Chinese medicine composition and its application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
空军后勤部卫生部: "《中草药处方选编》", 31 October 1971 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105477214A (en) * 2015-12-22 2016-04-13 青岛海之星生物科技有限公司 Spray for treating scapulohumeral periarthritis and preparation method thereof
CN107998246A (en) * 2018-01-18 2018-05-08 上海市普陀区人民医院 It is a kind of treat traumatic injury caused by chronic soft tissue injury or osteoarthrosis pain Chinese medicine composition and its application
CN107998246B (en) * 2018-01-18 2021-02-12 上海市普陀区人民医院 Traditional Chinese medicine composition for treating chronic soft tissue injury or osteoarthropathy caused by traumatic injury and application thereof

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Application publication date: 20141022