CN104107339A - Traditional Chinese medicine for treating femoral head necrosis - Google Patents
Traditional Chinese medicine for treating femoral head necrosis Download PDFInfo
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- CN104107339A CN104107339A CN201410277148.XA CN201410277148A CN104107339A CN 104107339 A CN104107339 A CN 104107339A CN 201410277148 A CN201410277148 A CN 201410277148A CN 104107339 A CN104107339 A CN 104107339A
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Abstract
The invention discloses a traditional Chinese medicine for treating femoral head necrosis, and relates to a traditional Chinese medicine, specifically relates to a traditional Chinese medicine for treating femoral head necrosis. The medicine is prepared from the following raw materials: long-noded pit viper, zaocys dhumnades, radix clematidis, preparemonkshd moter root, prepared kusnezoff monkshood root, gastrodia elata, scorpion, fleece flower root, tortoise plastron, ephedra, licorice, notopterygium root, cinnamon, rhizoma coptidis from Sichuan of China, prepared rhizome of rehmannia, radices saussureae, eaglewood, asarum, radix paeoniae rubrathe (unpeeled) root of common peony, frankincense, myrrh, prepared Arisaema erubescens, pericarpium citri reticulatae viride, drynaria rhizome, Poria cocos, rhizoma cyperi, bighead atractylodes rhizome, radix sileris, Angelica sinensis, dragon's blood, earthworm, musk, American ginseng, Ligusticum wallichii, radix salviae miltiorrhizae, Radix Astragali, pangolin, pilose antler, eucommia, Caulis Spatholobi, pseudo-ginseng, natral copper, radices cyathulae, saffron, cornu cervi degelatinatum and lanatechead saussurea herb with flower. The 46 ingredients are ground into a powder, and supplemented with 400-450 parts of honey and prepared into honey pills. The medicine solves the problem of long-term treatment of femur head necrosis without healing in the prior art.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to treat the Chinese medicine of femur head necrosis.
Background technology
Femur head necrosis is a Pathologic process, initially occurs in capital heavy burden district, and downright bad under stress, trabecular bone structure is damaged, i.e. micro-fracture and subsequently for the repair process of damaged bone tissue.Cause the reason of osteonecrosis not eliminate, repair imperfection, the process of damage-reparation continues, and causes femoral head structural change, collapse of the femoral head, distortion, arthritis, dysfunction.Femur head necrosis no doubt can cause slight illness, joint motion and heavy burden walking function obstacle, but people are not subject to the impact of " bad and dead " word implication terror, femur head necrosis pathological changes, after all limitation, involve indivedual joints, can alleviate, disappear and spontaneous recovery, even if serious, finally can also remedy by artificial hip joint replacing, still can recover walking ability.
There is the cureless shortcoming of femur head necrosis in existing femoral head necrosis therapeutic medication.
Summary of the invention
The invention provides a kind of Chinese medicine for the treatment of femur head necrosis, solved the cureless problem of the femur head necrosis existing in prior art.
For addressing the above problem, the present invention adopts following technical scheme: a kind of Chinese medicine for the treatment of femur head necrosis, by the raw material of following ratio of weight and number, made: Agkistrodon 2-4 part, Zaocys 45-55 part, Radix Clematidis 45-55 part, Radix Aconiti Preparata 8-12 part, Radix Aconiti Kusnezoffii Preparata 8-12 part, Rhizoma Gastrodiae 45-55 part, Scorpio 8-12 part, Radix Polygoni Multiflori 8-12 part, Carapax et Plastrum Testudinis 45-55 part, Herba Ephedrae 8-12 part, Radix Glycyrrhizae 8-12 part, Rhizoma Et Radix Notopterygii 8-12 part, Cortex Cinnamomi 8-12 part, Rhizoma Coptidis 8-12 part, Radix Rehmanniae Preparata 8-12 part, Radix Aucklandiae 8-12 part, Lignum Aquilariae Resinatum 8-12 part, Herba Asari 8-12 part, Radix Paeoniae Rubra 8-12 part, Olibanum 8-12 part, Myrrha 8-12 part, Rhizoma Arisaematis (processed) 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part, Rhizoma Drynariae 90-110 part, Poria 8-12 part, Rhizoma Cyperi 45-55 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Angelicae Sinensis 45-55 part, Sanguis Draxonis 45-55 part, Pheretima 8-12 part, Moschus 0.5-1.5 part, Radix Panacis Quinquefolii 8-12 part, Rhizoma Chuanxiong 45-55 part, Radix Salviae Miltiorrhizae 90-110 part, Radix Astragali 90-110 part, Squama Manis 45-55 part, Cornu Cervi Pantotrichum 8-12 part, Cortex Eucommiae 45-55 part, Caulis Spatholobi 45-55 part, Radix Notoginseng 45-55 part, Pyritum 8-12 part, Radix Cyathulae 8-12 part, Stigma Croci 8-12 part, Cornu Cervi Degelatinatum 45-55 part, Herba Saussureae Involueratae 45-55 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
Advantage of the present invention has: can treating caput femoris necrosis, effectively alleviate ailing.Have nontoxicly, have no side effect, therapeutic effect is good, the advantage that expense is low.
The specific embodiment
With best embodiment, the present invention is described in detail below.
Embodiment mono-
Treat a Chinese medicine for femur head necrosis, by the raw material of following ratio of weight and number, made: Agkistrodon 2-4 part, Zaocys 45-55 part, Radix Clematidis 45-55 part, Radix Aconiti Preparata 8-12 part, Radix Aconiti Kusnezoffii Preparata 8-12 part, Rhizoma Gastrodiae 45-55 part, Scorpio 8-12 part, Radix Polygoni Multiflori 8-12 part, Carapax et Plastrum Testudinis 45-55 part, Herba Ephedrae 8-12 part, Radix Glycyrrhizae 8-12 part, Rhizoma Et Radix Notopterygii 8-12 part, Cortex Cinnamomi 8-12 part, Rhizoma Coptidis 8-12 part, Radix Rehmanniae Preparata 8-12 part, Radix Aucklandiae 8-12 part, Lignum Aquilariae Resinatum 8-12 part, Herba Asari 8-12 part, Radix Paeoniae Rubra 8-12 part, Olibanum 8-12 part, Myrrha 8-12 part, Rhizoma Arisaematis (processed) 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part, Rhizoma Drynariae 90-110 part, Poria 8-12 part, Rhizoma Cyperi 45-55 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Angelicae Sinensis 45-55 part, Sanguis Draxonis 45-55 part, Pheretima 8-12 part, Moschus 0.5-1.5 part, Radix Panacis Quinquefolii 8-12 part, Rhizoma Chuanxiong 45-55 part, Radix Salviae Miltiorrhizae 90-110 part, Radix Astragali 90-110 part, Squama Manis 45-55 part, Cornu Cervi Pantotrichum 8-12 part, Cortex Eucommiae 45-55 part, Caulis Spatholobi 45-55 part, Radix Notoginseng 45-55 part, Pyritum 8-12 part, Radix Cyathulae 8-12 part, Stigma Croci 8-12 part, Cornu Cervi Degelatinatum 45-55 part, Herba Saussureae Involueratae 45-55 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
Embodiment bis-
Treat a Chinese medicine for femur head necrosis, by the raw material of following ratio of weight and number, made: Agkistrodon 2-3 part, Zaocys 45-50 part, Radix Clematidis 45-50 part, Radix Aconiti Preparata 8-10 part, Radix Aconiti Kusnezoffii Preparata 8-10 part, Rhizoma Gastrodiae 45-50 part, Scorpio 8-10 part, Radix Polygoni Multiflori 8-10 part, Carapax et Plastrum Testudinis 45-50 part, Herba Ephedrae 8-10 part, Radix Glycyrrhizae 8-10 part, Rhizoma Et Radix Notopterygii 8-10 part, Cortex Cinnamomi 8-10 part, Rhizoma Coptidis 8-10 part, Radix Rehmanniae Preparata 8-10 part, Radix Aucklandiae 8-10 part, Lignum Aquilariae Resinatum 8-10 part, Herba Asari 8-10 part, Radix Paeoniae Rubra 8-10 part, Olibanum 8-10 part, Myrrha 8-10 part, Rhizoma Arisaematis (processed) 8-10 part, Pericarpium Citri Reticulatae Viride 8-10 part, Rhizoma Drynariae 90-100 part, Poria 8-10 part, Rhizoma Cyperi 45-50 part, Rhizoma Atractylodis Macrocephalae 8-10 part, Radix Saposhnikoviae 8-10 part, Radix Angelicae Sinensis 45-50 part, Sanguis Draxonis 45-50 part, Pheretima 8-10 part, Moschus 0.5-1 part, Radix Panacis Quinquefolii 8-10 part, Rhizoma Chuanxiong 45-50 part, Radix Salviae Miltiorrhizae 90-100 part, Radix Astragali 90-100 part, Squama Manis 45-50 part, Cornu Cervi Pantotrichum 8-10 part, Cortex Eucommiae 45-50 part, Caulis Spatholobi 45-50 part, Radix Notoginseng 45-50 part, Pyritum 8-10 part, Radix Cyathulae 8-10 part, Stigma Croci 8-10 part, Cornu Cervi Degelatinatum 45-50 part, Herba Saussureae Involueratae 45-50 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
Embodiment tri-
Treat a Chinese medicine for femur head necrosis, by the raw material of following ratio of weight and number, made: Agkistrodon 3-4 part, Zaocys 50-55 part, Radix Clematidis 50-55 part, Radix Aconiti Preparata 10-12 part, Radix Aconiti Kusnezoffii Preparata 10-12 part, Rhizoma Gastrodiae 50-55 part, Scorpio 10-12 part, Radix Polygoni Multiflori 10-12 part, Carapax et Plastrum Testudinis 50-55 part, Herba Ephedrae 10-12 part, Radix Glycyrrhizae 10-12 part, Rhizoma Et Radix Notopterygii 10-12 part, Cortex Cinnamomi 10-12 part, Rhizoma Coptidis 10-12 part, Radix Rehmanniae Preparata 10-12 part, Radix Aucklandiae 10-12 part, Lignum Aquilariae Resinatum 10-12 part, Herba Asari 10-12 part, Radix Paeoniae Rubra 10-12 part, Olibanum 10-12 part, Myrrha 10-12 part, Rhizoma Arisaematis (processed) 10-12 part, Pericarpium Citri Reticulatae Viride 10-12 part, Rhizoma Drynariae 100-110 part, Poria 10-12 part, Rhizoma Cyperi 50-55 part, Rhizoma Atractylodis Macrocephalae 10-12 part, Radix Saposhnikoviae 10-12 part, Radix Angelicae Sinensis 50-55 part, Sanguis Draxonis 50-55 part, Pheretima 10-12 part, Moschus 1-1.5 part, Radix Panacis Quinquefolii 10-12 part, Rhizoma Chuanxiong 50-55 part, Radix Salviae Miltiorrhizae 100-110 part, Radix Astragali 100-110 part, Squama Manis 50-55 part, Cornu Cervi Pantotrichum 10-12 part, Cortex Eucommiae 50-55 part, Caulis Spatholobi 50-55 part, Radix Notoginseng 50-55 part, Pyritum 10-12 part, Radix Cyathulae 10-12 part, Stigma Croci 10-12 part, Cornu Cervi Degelatinatum 50-55 part, Herba Saussureae Involueratae 50-55 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
Usage of the present invention is: one day three times, take after mixing it with water early, middle and late half an hour after meal of every day, takes after mixing it with water 10 grams at every turn.
Toxicity test report: to Chinese medicine of the present invention, get 20 secondary Kunming kind white mice, body weight 18-22 gram, male and female half and half, according to the < < of Ministry of Public Health bureau of drug policy & administration study of tcm new drug guide > >, the present invention is carried out to toxicity test.
Get above-mentioned 20 white mice, every day early, each was once got after 0.01 gram, Chinese medicine of the present invention is taken after mixing it with water and white mice was carried out to gavage, continuous 7 days evening.After administration to the body weight of white mice, the mental status, hair color, autonomic activities, breathing, two just, the general status such as mouth and nose secretions observes, Continuous Observation 7 days.
After administration and viewing duration, the mental status of white mice is good, hair color is bright and clean, activity freely, eupnea.Dietary amount can, two just without in abnormal, mouth and nose without abnormal secretions, none animal dead, observes and to take off the mode of cervical vertebra, puts to death white mice on the 7th day, and all animals are carried out to gross necropsy, no abnormal.
Clinical experiment report: Patients with Aseptic Necrosis of Femoral symptom is divided into six stages: be divided into for 6 phases: the I phase, hip is asymptomatic, x-ray shows the spottiness increase in density of femoral head front upper place; The II phase, hip is asymptomatic, and x-ray performance can see that the clear necrotic zone of boundary has newborn osteoplastic wall; The III phase, the intermittent pain of groin, hip joint activity is slightly limited; X-ray performance stock bone slightly flattens, and joint space is normal, has trickle x-ray to see through image (meniscus sign) on edge-on picture; The IV phase, intermittent pain increases the weight of suddenly, and hip joint range of activity is limited, and x-ray performance stock bone parts subsides, and capital ball-type degree interrupts, and at necrotic bone edge, can see articular surface fracture; , there is strong pain the V phase, x-ray performance stock bone distortion, and joint space narrows down, and has under little hyperosteogeny, cystis degenerationization femoral head cartilage and the osteoarthritis sign such as acetabular bone heavy burden region formation; , there are serious pain and joint movement disorder the VI phase, and x-ray performance has femoral head distortion, the joint space performance of full hip-joint osteoarthritis such as narrow down.
There are respectively 20 Patients with Aseptic Necrosis of Femorals in clinical each stage, above-mentioned patient uses respectively medicine of the present invention, according to above-mentioned using method treatment, through checking, 20 patients of I phase all cure, 20 patients of II phase all cure, 20 patients of III phase all cure, and 20 patients of IV phase all cure, and 20 patients of V phase have 19 to be cured completely, the VI phase is suffered from 20 patients has 17 to be cured completely, and 4 remaining head necrosis patient symptoms obviously alleviate.
I phase, II phase, III phase, IV phase patient's cure rate be 100%, V phase patient cure rate I 95%, VI phase patient cure rate 85%, it is heavier that invalid patient belongs to the state of an illness more, and affect normal therapeutic with other complication.
Finally it should be noted that: obviously, above-described embodiment is only for example of the present invention is clearly described, and the not restriction to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without also giving all embodiments.And the apparent variation of being amplified out thus or change are still among protection scope of the present invention.
Claims (3)
1. a Chinese medicine for the treatment of femur head necrosis, is characterized in that, by the raw material of following ratio of weight and number, is made: Agkistrodon 2-4 part, Zaocys 45-55 part, Radix Clematidis 45-55 part, Radix Aconiti Preparata 8-12 part, Radix Aconiti Kusnezoffii Preparata 8-12 part, Rhizoma Gastrodiae 45-55 part, Scorpio 8-12 part, Radix Polygoni Multiflori 8-12 part, Carapax et Plastrum Testudinis 45-55 part, Herba Ephedrae 8-12 part, Radix Glycyrrhizae 8-12 part, Rhizoma Et Radix Notopterygii 8-12 part, Cortex Cinnamomi 8-12 part, Rhizoma Coptidis 8-12 part, Radix Rehmanniae Preparata 8-12 part, Radix Aucklandiae 8-12 part, Lignum Aquilariae Resinatum 8-12 part, Herba Asari 8-12 part, Radix Paeoniae Rubra 8-12 part, Olibanum 8-12 part, Myrrha 8-12 part, Rhizoma Arisaematis (processed) 8-12 part, Pericarpium Citri Reticulatae Viride 8-12 part, Rhizoma Drynariae 90-110 part, Poria 8-12 part, Rhizoma Cyperi 45-55 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Angelicae Sinensis 45-55 part, Sanguis Draxonis 45-55 part, Pheretima 8-12 part, Moschus 0.5-1.5 part, Radix Panacis Quinquefolii 8-12 part, Rhizoma Chuanxiong 45-55 part, Radix Salviae Miltiorrhizae 90-110 part, Radix Astragali 90-110 part, Squama Manis 45-55 part, Cornu Cervi Pantotrichum 8-12 part, Cortex Eucommiae 45-55 part, Caulis Spatholobi 45-55 part, Radix Notoginseng 45-55 part, Pyritum 8-12 part, Radix Cyathulae 8-12 part, Stigma Croci 8-12 part, Cornu Cervi Degelatinatum 45-55 part, Herba Saussureae Involueratae 45-55 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
2. a kind of Chinese medicine for the treatment of femur head necrosis as claimed in claim 1, is characterized in that, is made: Agkistrodon 2-3 part by the raw material of following ratio of weight and number, Zaocys 45-50 part, Radix Clematidis 45-50 part, Radix Aconiti Preparata 8-10 part, Radix Aconiti Kusnezoffii Preparata 8-10 part, Rhizoma Gastrodiae 45-50 part, Scorpio 8-10 part, Radix Polygoni Multiflori 8-10 part, Carapax et Plastrum Testudinis 45-50 part, Herba Ephedrae 8-10 part, Radix Glycyrrhizae 8-10 part, Rhizoma Et Radix Notopterygii 8-10 part, Cortex Cinnamomi 8-10 part, Rhizoma Coptidis 8-10 part, Radix Rehmanniae Preparata 8-10 part, Radix Aucklandiae 8-10 part, Lignum Aquilariae Resinatum 8-10 part, Herba Asari 8-10 part, Radix Paeoniae Rubra 8-10 part, Olibanum 8-10 part, Myrrha 8-10 part, Rhizoma Arisaematis (processed) 8-10 part, Pericarpium Citri Reticulatae Viride 8-10 part, Rhizoma Drynariae 90-100 part, Poria 8-10 part, Rhizoma Cyperi 45-50 part, Rhizoma Atractylodis Macrocephalae 8-10 part, Radix Saposhnikoviae 8-10 part, Radix Angelicae Sinensis 45-50 part, Sanguis Draxonis 45-50 part, Pheretima 8-10 part, Moschus 0.5-1 part, Radix Panacis Quinquefolii 8-10 part, Rhizoma Chuanxiong 45-50 part, Radix Salviae Miltiorrhizae 90-100 part, Radix Astragali 90-100 part, Squama Manis 45-50 part, Cornu Cervi Pantotrichum 8-10 part, Cortex Eucommiae 45-50 part, Caulis Spatholobi 45-50 part, Radix Notoginseng 45-50 part, Pyritum 8-10 part, Radix Cyathulae 8-10 part, Stigma Croci 8-10 part, Cornu Cervi Degelatinatum 45-50 part, Herba Saussureae Involueratae 45-50 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
3. a kind of Chinese medicine for the treatment of femur head necrosis as claimed in claim 1, is characterized in that, is made: Agkistrodon 3-4 part by the raw material of following ratio of weight and number, Zaocys 50-55 part, Radix Clematidis 50-55 part, Radix Aconiti Preparata 10-12 part, Radix Aconiti Kusnezoffii Preparata 10-12 part, Rhizoma Gastrodiae 50-55 part, Scorpio 10-12 part, Radix Polygoni Multiflori 10-12 part, Carapax et Plastrum Testudinis 50-55 part, Herba Ephedrae 10-12 part, Radix Glycyrrhizae 10-12 part, Rhizoma Et Radix Notopterygii 10-12 part, Cortex Cinnamomi 10-12 part, Rhizoma Coptidis 10-12 part, Radix Rehmanniae Preparata 10-12 part, Radix Aucklandiae 10-12 part, Lignum Aquilariae Resinatum 10-12 part, Herba Asari 10-12 part, Radix Paeoniae Rubra 10-12 part, Olibanum 10-12 part, Myrrha 10-12 part, Rhizoma Arisaematis (processed) 10-12 part, Pericarpium Citri Reticulatae Viride 10-12 part, Rhizoma Drynariae 100-110 part, Poria 10-12 part, Rhizoma Cyperi 50-55 part, Rhizoma Atractylodis Macrocephalae 10-12 part, Radix Saposhnikoviae 10-12 part, Radix Angelicae Sinensis 50-55 part, Sanguis Draxonis 50-55 part, Pheretima 10-12 part, Moschus 1-1.5 part, Radix Panacis Quinquefolii 10-12 part, Rhizoma Chuanxiong 50-55 part, Radix Salviae Miltiorrhizae 100-110 part, Radix Astragali 100-110 part, Squama Manis 50-55 part, Cornu Cervi Pantotrichum 10-12 part, Cortex Eucommiae 50-55 part, Caulis Spatholobi 50-55 part, Radix Notoginseng 50-55 part, Pyritum 10-12 part, Radix Cyathulae 10-12 part, Stigma Croci 10-12 part, Cornu Cervi Degelatinatum 50-55 part, Herba Saussureae Involueratae 50-55 part, above-mentioned totally 46 taste medicines are ground into powder, add the Mel of 400-450 part to make honeyed pill.
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| CN201410277148.XA CN104107339A (en) | 2014-06-20 | 2014-06-20 | Traditional Chinese medicine for treating femoral head necrosis |
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| CN201410277148.XA CN104107339A (en) | 2014-06-20 | 2014-06-20 | Traditional Chinese medicine for treating femoral head necrosis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958484A (en) * | 2015-05-29 | 2015-10-07 | 马海春 | traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and preparing method of traditional Chinese medicine unguent |
| CN105963471A (en) * | 2016-08-01 | 2016-09-28 | 黄平县兴且民族民间中草医药科学发展有限责任公司 | Traditional Chinese medicine formula for treating femoral head necrosis |
| CN105998261A (en) * | 2016-06-29 | 2016-10-12 | 王树华 | Traditional Chinese medicine for treating femoral head osteonecrosis, preparation method thereof and femoral head osteonecrosis treatment plaster |
-
2014
- 2014-06-20 CN CN201410277148.XA patent/CN104107339A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958484A (en) * | 2015-05-29 | 2015-10-07 | 马海春 | traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and preparing method of traditional Chinese medicine unguent |
| CN105998261A (en) * | 2016-06-29 | 2016-10-12 | 王树华 | Traditional Chinese medicine for treating femoral head osteonecrosis, preparation method thereof and femoral head osteonecrosis treatment plaster |
| CN105963471A (en) * | 2016-08-01 | 2016-09-28 | 黄平县兴且民族民间中草医药科学发展有限责任公司 | Traditional Chinese medicine formula for treating femoral head necrosis |
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