CN104083711A - Traditional Chinese medicine preparation for treating rectal cancer - Google Patents

Abstract

A traditional Chinese medicine preparation for treating rectal cancer comprises the raw materials: 10 parts of semen persicae, 10 parts of flos carthami, 12 parts of radix angelicae sinensis, 30 parts of Chinese sage herb, 15 parts of rhizoma curcumae, 15 parts of pangolin scales, 6 parts of radix et rhizoma rhei, 30 parts of herba scutellariae barbatae and 30 parts of spreading hedyotis herb. A preparation method for the traditional Chinese medicine preparation comprises: weighing 10 parts of semen persicae, 10 parts of flos carthami, 12 parts of radix angelicae sinensis, 30 parts of Chinese sage herb, 15 parts of rhizoma curcumae, 15 parts of pangolin scales, 6 parts of radix et rhizoma rhei, 30 parts of herba scutellariae barbatae and 30 parts of spreading hedyotis herb, respectively preparing decoction pieces, performing stewing sterilization for 30-60 min by using a pressure cooker, and airing to dry to obtain aseptic raw materials; and preparing the traditional Chinese medicine preparation from the obtained aseptic raw materials. The traditional Chinese medicine preparation has the efficacy of clearing heat and detoxifying, softening hardness and dissipating binds, dispersing swelling and resisting cancer, and is used to treat rectal cancer.

Description

The Chinese medicine preparation for the treatment of rectal cancer

Technical field

The present invention relates to field of traditional Chinese; Be specifically related to a kind of Chinese medicine preparation for the treatment of rectal cancer.

Background technology

Rectal cancer: referring to from pectinate line to the cancer between proctosigmoid intersection, is one of modal malignant tumor of digestive tract.That to be only second to the ratio that the most common part that harmonization of the stomach esophageal carcinoma is colorectal cancer (accounting for 65% left and right) most gene patients person below 30 years old more than 40 years old accounts for the more common men and women of 15% male be 2-3 to a kind of Cancer Mortality common in gastrointestinal tract: 1, rectal cancer is one way of life mode disease.At present, it has leapt to second in cancer ranking list, so diet and life style are the seeds of trouble of cancer.Similar due to the origin cause of formation and symptom, rectal cancer conventionally and colon cancer together mentioned.The cause of disease of rectal cancer is still not fully aware of at present, and its morbidity is relevant with social environment, dietary habit, inherited genetic factors etc.Rectal polyp is also the high risk factor of rectal cancer.Substantially be recognized that at present Animal fat and protein absorption are too high, dietary fiber Deficiency of Intake is the high risk factor that rectal cancer occurs.Early rectal tumor majority is asymptomatic, and bowl evacuation habit change, hemafecia, bloody purulent stool, tenesmus, constipation, diarrhoea etc. appear in rectal cancer while growing into a certain degree.Stool is tapered, and has the defecation even cachexia of blocking, become thin late period.When the surrounding organs such as tumor invading bladder, urethra, vagina, occur that urinary tract infection symptom, vagina flow out liquid manure, sacrum portion and perineal position pain, lower limbs edema etc.The other medicines for the treatment of this disease in prior art exist therapeutic effect not obvious, the technological deficiency that side effect is large.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation with heat-clearing and toxic substances removing, hard masses softening and resolving, detumescence anticancer function, be used for the treatment of rectal cancer.

Technical scheme of the present invention: the raw material of Chinese medicine preparation of the present invention and each component consumption thereof are groped in a large number to sum up through inventor and drawn, each component amount all has good effect within the scope of this: 10 parts, Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Hedyotidis Diffusaes.

For reaching heat-clearing and toxic substances removing, hard masses softening and resolving, detumescence anticancer function, the present invention selects 30 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, Herba Hedyotidis Diffusae to combine, by these drug regimens, make each efficacy of drugs produce synergism, thereby can effectively treat rectal cancer.In the raw materials of traditional Chinese medicinal materials of choosing, its effect and pharmacological action respectively:

Semen Persicae: the dry mature seed of rosaceous plant Fructus Persicae Amygdalus persica L. or Prunus davidiana Amygdalus davidiana (Carr.) C.de Vos ex Henry.[meridian distribution of property and flavor] bitter, sweet, flat.GUIXIN, liver, large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.

Flos Carthami: [chemical composition] is containing carthamin, neocarthamin, Flos Carthami quinone glycoside, Flos Carthami polysaccharide, Palmic acid, cinnamic acid, lauric acid.[nature and flavor] are warm in nature, acrid in the mouth.[function cures mainly] promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.

Radix Angelicae Sinensis: [chemical composition] contains basic lactone, n-butene acyl lactone, ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.[meridian distribution of property and flavor] is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Herba Salviae Chinensis: i.e. Salvia chinensis.Annual herb, high 20-70cm.Root multi-branched, taproot is not obvious, yellowish-brown.[nature and flavor] acrid in the mouth; Bitter; Cold nature.[return through] returns liver; Spleen channel.[function cures mainly] blood circulation promoting and blood stasis dispelling; Clearing away heat-damp and promoting diuresis; Mass dissipating and swelling eliminating.Main menoxenia; Dysmenorrhea; Amenorrhea; Metrorrhagia, has blood in stool; Jaundice due to damp-heat; Hot toxic-heat and blood stasis; Drench pain; Leukorrhagia; Rheumatic ostalgia; Scrofula; Skin ulcer is swollen; Acute mastitis; Herpes zoster; Leprosy; Traumatic injury wound is swollen.

Rhizoma Curcumae: [Chinese crude drug formal name used at school]: Rhizoma Curcumae (Rhizoma Curcumae).[English name]: Aeruginous Turmeric Rhizome.Rhizome claims " Rhizoma Curcumae ", hyoscine, cure mainly " lump in the abdomen, gathers for coagulation of QI-blood, trusted subordinate's distending pain, and dyspepsia does not disappear, women's blood stasis amenorrhea, and traumatic injury is had a pain." tuber claims " green filament Radix Curcumae ".Rhizome is containing volatile oil 1-1.5%.In oil, main component is sesquiterpene alcohols, α-camphorene and press olein.In addition still starch-containing, mucus and resin etc.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.[extracts] " Chinese Pharmacopoeia ".Antibacterial action: Rhizoma Curcumae volatile oil in vitro can suppress staphylococcus aureus.The growth of beta hemolytic streptococcus, escherichia coli, Bacillus typhi, vibrio cholera etc.Antiinflammatory action: the peritonitis that mouse gavaging the essential oil from Curcuma wenyujin 200mg/kg Dichlorodiphenyl Acetate produces has the inhibitory action showing very much, mouse peritoneal injection the essential oil from Curcuma wenyujin 200mg/kg has obvious inhibitory action to scald property local edema, ear's inflammation that lumbar injection 100m/kg causes Oleum Tiglii has obvious inhibitory action, rats by intraperitoneal injection volatile oil 75mg/kg/ days, had obvious inhibitory action to subcutaneous granuloma induced by implantation of cotton pellets hypertrophy after 9 days.

Squama Manis is a kind of Chinese medicine, also has the names such as big gun Squama Manis, stir-baked SQUAMA MANITIS.After generally being concocted by the scute of Manitis (Squama Manis), use.Concocting method has that burning, shortcake are processed, processed with vinegar, urine of baby boys are processed, fry, parching with earth, stir-baked in powder of CONCHA MERETRICIS SEU CYCLINAE.[meridian distribution of property and flavor]: salty in the mouth, cool in nature.Enter liver, stomach warp.[effect]: the routed carbuncle of detumescence, search wind active, the stimulating milk secretion of stimulating the menstrual flow.[curing mainly]: control carbuncle skin ulcer swollen, anemofrigid-damp arthralgia, amenorrhea, galactostasis, has blood in stool.

Radix Et Rhizoma Rhei: the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill..Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria.Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.

Herba Scutellariae Barbatae: another name Herba hyperici attenuati, thin Radix Scutellariae, toothbrush grass, Tian Jicao, Rheum alexandrae Batal. a kind of reed mentioned in ancient books, narrow leaf Herba Scutellariae indicae.Formal name used at school Portulaca grandilora.The lower portion of the stem crawls to take root, and top is upright, and stem is square, green.For tubular flower order, Labiatae, Scutellaria plant, be distributed in the ground such as park of Argentina, Brazil south, Uruguay and China's Mainland, be often born in ease raw, originate in South America, the dry aerial parts of Herba Scutellariae Barbatae, have heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.Nature and flavor: hide pungent; Bitter; Cold in nature.Gui Jing: return lung meridian; Liver Channel; Kidney channel.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice, has sore throat, lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.

Herba Hedyotidis Diffusae: be the annual draft that hangs down loosely, high 15-50cm.Root is elongated, and branch is spent in vain.The slightly square or oblate cylindricality of stem, Glabrous, sends multi-branched from base portion.Spring at florescence.Seed brown color, tiny, and 3 corner angle.Its patent medicine bitter in the mouth, light, cold in nature.Main effect is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.In clinical practice, if find, Herba Hedyotidis Diffusae compatibility is proper, can treat various diseases.Another name: Herba Hedyotidis Diffusae, tang Huang, Serpentis needle grass, Radix Picriae felterrae, two leaf humulus, spend cross grass, sharp knife grass, JIAMENGCAO, Herba Otteliae Alismoidis, Serpentis Lei grass, crane SHECAO in vain.Cure mainly: dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal inflammation; Jaundice due to damp-heat; Be good at the multiple cancerous protuberance for the treatment of.

For Da Gengjia result of use, the present invention also provides the preparation method of this Chinese medicine preparation; Its preparation method: take 30 parts, 10 parts, raw material Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, Herba Hedyotidis Diffusae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.

Chinese medicine for outer use of the present invention has heat-clearing and toxic substances removing, hard masses softening and resolving, detumescence anticancer function, is used for the treatment of rectal cancer.So far, still do not find report and the application about Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the Chinese medicine preparation that has better curative effect, thereby has completed the present invention.

Specific implementation method

Treatment rectal cancer of the present invention, its raw material is: 10 parts, Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Hedyotidis Diffusaes.

Its preparation method: take 30 parts, 10 parts, raw material Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, Herba Hedyotidis Diffusae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.

Claims (2)

1. a Chinese medicine preparation for the treatment of rectal cancer, is characterized in that: its raw material is; 10 parts, Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, 30 parts of Herba Hedyotidis Diffusaes.

2. according to the Chinese medicine preparation for the treatment of rectal cancer claimed in claim 1, it is characterized in that: its preparation method: take 30 parts, 10 parts, raw material Semen Persicae, 10 parts, Flos Carthami, 12 parts of Radix Angelicae Sinensis, 30 parts of Herba Salviae Chinensiss, 15 parts of Rhizoma Curcumae, 15 parts of Squama Manis, 6 parts of Radix Et Rhizoma Rhei, 30 parts of Herba Scutellariae Barbataes, Herba Hedyotidis Diffusae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.