CN104081180B - 用于冷冻等分器的机器人末端执行器以及从生物样本中取出冷冻等分试样的方法 - Google Patents

用于冷冻等分器的机器人末端执行器以及从生物样本中取出冷冻等分试样的方法 Download PDF

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Publication number
CN104081180B
CN104081180B CN201380006859.7A CN201380006859A CN104081180B CN 104081180 B CN104081180 B CN 104081180B CN 201380006859 A CN201380006859 A CN 201380006859A CN 104081180 B CN104081180 B CN 104081180B
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CN
China
Prior art keywords
sample
frozen
frozen sample
end effector
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201380006859.7A
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English (en)
Chinese (zh)
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CN104081180A (zh
Inventor
M·布鲁威尔勒
S·索克汉瓦尔
C·康斯坦丁尼奥
M·罗森
T·巴斯克
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CRYOXTRACT INSTR LLC
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CRYOXTRACT INSTR LLC
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Publication of CN104081180A publication Critical patent/CN104081180A/zh
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Expired - Fee Related legal-status Critical Current
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J15/00Gripping heads and other end effectors
    • B25J15/0019End effectors other than grippers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F17/00Methods or apparatus for determining the capacity of containers or cavities, or the volume of solid bodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42Low-temperature sample treatment, e.g. cryofixation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025Fluid level sensing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S901/00Robots
    • Y10S901/30End effector
    • Y10S901/41Tool

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  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Robotics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201380006859.7A 2012-01-26 2013-01-28 用于冷冻等分器的机器人末端执行器以及从生物样本中取出冷冻等分试样的方法 Expired - Fee Related CN104081180B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/359,301 2012-01-26
US13/359,301 US9134202B2 (en) 2012-01-26 2012-01-26 Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples
PCT/US2013/023453 WO2013113001A1 (en) 2012-01-26 2013-01-28 Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples

Publications (2)

Publication Number Publication Date
CN104081180A CN104081180A (zh) 2014-10-01
CN104081180B true CN104081180B (zh) 2016-06-29

Family

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Family Applications (1)

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CN201380006859.7A Expired - Fee Related CN104081180B (zh) 2012-01-26 2013-01-28 用于冷冻等分器的机器人末端执行器以及从生物样本中取出冷冻等分试样的方法

Country Status (8)

Country Link
US (2) US9134202B2 (enExample)
EP (1) EP2807465A4 (enExample)
JP (1) JP2015510117A (enExample)
CN (1) CN104081180B (enExample)
AU (1) AU2013211839B2 (enExample)
BR (1) BR112014018057A8 (enExample)
CA (1) CA2862894A1 (enExample)
WO (1) WO2013113001A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10363367B2 (en) * 2013-03-28 2019-07-30 Sanofi-Aventis Deutschland Gmbh Filling device for a drug delivery device and system with a filling device and drug delivery device
WO2015107644A1 (ja) * 2014-01-16 2015-07-23 株式会社島津製作所 分析装置
US9766473B1 (en) * 2014-02-03 2017-09-19 Automation Engineering, Inc. Automated UV calibration, motorized optical target and automatic surface finder for optical alignment and assembly robot
US9815063B2 (en) * 2014-10-22 2017-11-14 Siemens Medical Solutions Usa, Inc. Radionuclide assay station
KR101655586B1 (ko) * 2014-11-28 2016-09-07 현대자동차주식회사 검사 그리퍼 및 이를 이용한 검사 방법
US10159971B2 (en) * 2015-05-03 2018-12-25 Clear Labs Inc. Apparatus and method for economic, fast and easy sampling of food and environmental samples
TWD176690S (zh) * 2015-09-24 2016-06-21 上銀科技股份有限公司 器械座之部分
IT201600079771A1 (it) * 2016-07-29 2018-01-29 I M A Industria Macch Automatiche S P A In Sigla Ima S P A Gruppo di pesatura
US11116352B2 (en) * 2016-09-13 2021-09-14 Kerry Luxembourg S.à.r.l. Beverage preparation system
CN107843453B (zh) * 2017-12-21 2024-01-23 上海泽泉科技股份有限公司 可调速手持低温样本分装仪
JP7084135B2 (ja) * 2017-12-26 2022-06-14 川崎重工業株式会社 エンドエフェクタ、ロボット、及びロボットシステム
CN110731333B (zh) * 2018-07-18 2021-11-19 Scl生物科技有限公司 细胞分注暨储存装置及其方法
JP6859992B2 (ja) * 2018-09-28 2021-04-14 セイコーエプソン株式会社 制御方法、ロボット及びロボットシステム
CN110053057B (zh) * 2019-04-28 2023-08-18 深圳市万臣科技有限公司 移液组件
US12168302B2 (en) 2019-12-16 2024-12-17 Tohoku University Grasping device, control method, and program
JP7650887B2 (ja) * 2019-12-30 2025-03-25 オーリス ヘルス インコーポレイテッド ロボット医療用システム
CN115788339B (zh) * 2023-02-03 2023-04-25 北京中联勘工程技术有限责任公司 一种岩土工程勘察破碎岩石取芯装置
CN116197926B (zh) * 2023-02-28 2025-07-18 北京理工大学 基于声镊的无接触核酸采集机器人
CN119618784A (zh) * 2023-09-14 2025-03-14 中国石油天然气集团有限公司 轴压式制作岩心的装置和轴压式制作室内岩心的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023782A2 (en) 1998-10-16 2000-04-27 Intelligent Automation Systems Continuous processing automated workstation
US6103518A (en) 1999-03-05 2000-08-15 Beecher Instruments Instrument for constructing tissue arrays
FR2802640B1 (fr) * 1999-12-17 2003-01-03 Pasteur Sanofi Diagnostics Dispositif et procede de prelevement d'echantillon biologique
WO2003050509A1 (en) 2000-11-30 2003-06-19 Instrumedics Inc. A method for creating a frozen tissue array
US6756095B2 (en) 2001-01-10 2004-06-29 Avery Dennison Corporation Heat-sealable laminate
US6534307B1 (en) 2001-02-08 2003-03-18 Clinomics Biosciences, Inc. Frozen tissue microarrayer
US6468783B1 (en) 2001-04-09 2002-10-22 Beecher Instruments Punch-changing tissue array instrument
CA2377213A1 (en) * 2001-03-20 2002-09-20 Ortho-Clinical Diagnostics, Inc. Method for providing clinical diagnostic services
JP2002340749A (ja) * 2001-05-11 2002-11-27 Dainakomu:Kk 生体高分子の保存および切断方法
US6635414B2 (en) 2001-05-22 2003-10-21 Integrated Biosystems, Inc. Cryopreservation system with controlled dendritic freezing front velocity
JP2004093440A (ja) * 2002-09-02 2004-03-25 Hitachi Instruments Service Co Ltd 微細管を用いた試料採取装置
US7753085B2 (en) 2002-12-03 2010-07-13 Forhealth Technologies, Inc. Automated drug preparation apparatus including automated drug reconstitution
EP2444788A3 (en) 2004-06-18 2012-08-22 Covance, Inc. Moisture barrier for a microarrayer
FR2878859B1 (fr) 2004-12-02 2007-03-23 Alphelys Sarl Dispositif de prelevement de carottes pour tissue array
US7405056B2 (en) 2005-03-02 2008-07-29 Edward Lam Tissue punch and tissue sample labeling methods and devices for microarray preparation, archiving and documentation
EP1971810B1 (en) 2006-01-13 2020-07-01 President and Fellows of Harvard College Systems, methods, and devices for frozen sample distribution
US8616072B2 (en) 2006-02-13 2013-12-31 The Johns Hopkins University System and methods for sampling materials
EP2032256A1 (en) 2006-05-03 2009-03-11 Ncl New Concept Lab Gmbh Device and method for chemical, biochemical, biological and physical analysis, reaction, assay and more
US20100152895A1 (en) 2008-12-05 2010-06-17 Zhengshan Dai Shock freezer and system for preparing samples for analysis using the same
US20140335554A1 (en) 2010-12-01 2014-11-13 President And Fellows Of Harvard College Apparatus and methods for aliquotting frozen samples

Also Published As

Publication number Publication date
JP2015510117A (ja) 2015-04-02
EP2807465A1 (en) 2014-12-03
EP2807465A4 (en) 2015-12-30
AU2013211839B2 (en) 2016-10-27
CA2862894A1 (en) 2013-08-01
BR112014018057A8 (pt) 2017-07-11
US9528916B2 (en) 2016-12-27
US9134202B2 (en) 2015-09-15
US20130192391A1 (en) 2013-08-01
AU2013211839A1 (en) 2014-06-26
WO2013113001A1 (en) 2013-08-01
CN104081180A (zh) 2014-10-01
US20160041071A1 (en) 2016-02-11
BR112014018057A2 (enExample) 2017-06-20

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