CN104069302B - A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application - Google Patents
A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application Download PDFInfo
- Publication number
- CN104069302B CN104069302B CN201410321729.9A CN201410321729A CN104069302B CN 104069302 B CN104069302 B CN 104069302B CN 201410321729 A CN201410321729 A CN 201410321729A CN 104069302 B CN104069302 B CN 104069302B
- Authority
- CN
- China
- Prior art keywords
- composition
- present
- black fungus
- coconut husk
- husk charcoal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of composition of the toxin expelling that can be relaxed bowel in intestinal absorption, the mass fraction of each component is in described composition：Ultra-fine black fungus powder 5%~95%, coconut husk charcoal 95%~5%, the present invention also provide the preparation method and application of above-mentioned composition.Advantages of the present invention shows：Black fungus in the present invention makes it be beneficial to discharge by that after ultramicro grinding, can adsorb the water of several times itself so as to soften stool, coconut husk charcoal will not be absorbed in enteron aisle, but can be absorption enterogenous endotoxin, reach toxin expelling purpose, both share effect and complement each other, and can reach optimum efficiency；One layer of enteric coating of outer layer covers of the present invention, makes product be played a role in enteron aisle, will not be destroyed by the strong acidic environment in stomach, and effect reaches highest；It is raw material that the present invention uses black fungus powder and coconut husk charcoal, and composition safety is nontoxic to human body.
Description
Technical field
The present invention relates to a kind of composition of the toxin expelling that can be relaxed bowel in intestinal absorption, especially with black fungus and coconut husk
Composition prepared by charcoal and preparation method thereof.
Background technology
Constipation, unhygienic diet, environmental pollution, live it is irregular cause enteron aisle bowel movement function exception, enterogenous endotoxin accumulation, table
It is now children's heavy metal poisoning, teenager's face acnes, person in middle and old age's brown plaque, hemorrhoid.And the cleaning sold in the market
The product of enteron aisle contains lead to diarrhea composition mostly, and long-term use may cause function of intestinal canal disorderly, or even trigger malignant change.
Black fungus contains abundant plant collagen composition, and it has stronger suction-operated, disappears to being not intended to being difficult under eating
The foreign matters such as hair, husk, wooden slag, sand, the metal fillings of change also have dissolving and oxidation.Often eating black fungus can play cleaning
Alimentary canal, clearing stomach wash the effect of intestines, particularly to being engaged in ore extraction, metallurgy, cement manufacture, haircut, flour processing, cotton spinning hair
The workman of the serious work posts of air pollution such as spinning.Often edible black fungus can also play good health-care effect, and black fungus is to courage knot
Stone, kidney stone also have preferable neutralizing function, because the vegetable soda contained by it has promotes alimentary canal, the various bodies of gland of the urinary tract point
The characteristic secreted, vegetable soda can cooperate with these secretion to be catalyzed calculus, lubricate enteron aisle, excrete calculus.Coconut husk charcoal has inhales
Attached effect, can adsorb enterogenous endotoxin, reach toxin expelling purpose.
Chinese patent literature CN200710113553.8, the applying date is on December 26th, 2007, discloses one kind with apple
Pectin is functional food of runchang detoxification of key component and preparation method thereof.But on black fungus and coconut husk charcoal as raw material
Functional food, yet there are no report.
The content of the invention
The purpose of the present invention is directed to deficiency of the prior art, there is provided a kind of to be relaxed bowel toxin expelling in intestinal absorption
Composition.
The another purpose of the present invention is to provide the preparation method of above-mentioned composition.
Another purpose of the present invention is to provide the purposes of above-mentioned composition.
To achieve the above object, the present invention is adopted the technical scheme that：
A kind of composition of the toxin expelling that can be relaxed bowel in intestinal absorption, the mass fraction of each component in described composition
For：Ultra-fine black fungus powder 5%~95%, coconut husk charcoal 95%~5%.
The mass fraction of each component is in described composition：Ultra-fine black fungus powder 40%~55%, coconut husk charcoal 60%~45%.
The mass fraction of each component is in described composition：Ultra-fine black fungus powder 45%, coconut husk charcoal 55%.
Described composition is tablet or capsule.
Described ultra-fine black fungus powder is 10 microns with subordinate's fine powder.
To realize above-mentioned second purpose, the present invention is adopted the technical scheme that：
It is a kind of intestinal absorption can relax bowel toxin expelling composition preparation method, comprise the following steps：Will be ultra-fine black
After auricularia auriculajudae powder is mixed with coconut husk charcoal by above-mentioned mass fraction, particle is made, enteric is used after being fitted into capsulae enterosolubilis or being pressed into tablet
Clothing material is coated, drying, packing.
To realize above-mentioned 3rd purpose, the present invention is adopted the technical scheme that：
Purposes of the described composition in the medicine/food/health products for relaxing bowel toxin expelling are prepared.
It should be noted that the one kind of described coconut husk charcoal for activated carbon, is the unformed shot-like particle of black, refined by coconut husk
Form.
The invention has the advantages that：
1st, the black fungus in the present invention makes by that after ultramicro grinding, can adsorb the water of several times itself so as to soften stool
It is beneficial to discharge, and coconut husk charcoal will not be absorbed in enteron aisle, but can be absorption enterogenous endotoxin, reach toxin expelling purpose, Liang Zhehe
Complemented each other with effect, effect is significant is better than alone black fungus or coconut husk charcoal, can reach optimum efficiency.
2nd, one layer of enteric coating of outer layer covers of the present invention, makes product be played a role in enteron aisle, will not be by the highly acid in stomach
Environmental disruption, effect reaches highest.
3rd, it is raw material that the present invention uses black fungus powder and coconut husk charcoal, and composition safety is nontoxic to human body.
Specific embodiment
It is prepared by the composition of the invention of embodiment 1（One）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 5%：After 95% mixes, particle is made, loads enteric glue
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It is prepared by the composition of the invention of embodiment 2（Two）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 95%：After 5% mixes, particle is made, loads enteric glue
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It is prepared by the composition of the invention of embodiment 3（Three）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 35%：After 65% mixes, particle is made, loads enteric
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It is prepared by the composition of the invention of embodiment 4（Four）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 65%：After 35% mixes, particle is made, loads enteric
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It is prepared by the composition of the invention of embodiment 5（Five）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 45%：After 55% mixes, particle is made, loads enteric
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It is prepared by the composition of the invention of embodiment 6（Six）
Agaric is selected, removes impurity and stalk portion, cleaned, sterilizing, after drying at a temperature of 65 ~ 75 DEG C, ultramicro grinding is into 10
Micron with subordinate's fine powder, by ultra-fine black fungus powder and coconut husk charcoal in mass ratio 55%：After 45% mixes, particle is made, loads enteric
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing obtains finished product.
It should be noted that the preparation method and equipment described in embodiment 1-6 are general pharmaceutical equipment, described enteric glue
Capsule is purchased from Xinchang, Zhejiang scholar Ao capsules Co., Ltd, and described enteric-coating material is selected from Shanghai City Ka Lekang packaging techniques
Co., Ltd's patented product Opadry (Opadry).
The composition of the invention of embodiment 7 relax bowel effect of ejecting poison detection experiment
1. test method
This experiment is divided into 3 groups：Test group, control group 1, control group 2, every group of each 40 people.Test group takes embodiment 5
The capsule of preparation, twice daily, 10 every time, a 5g；Control group 1 takes the capsule that black fungus powder is made, twice daily, often
Secondary 10, a 5g；Control group 2 takes the capsule that coconut husk charcoal is made, twice daily, 10 every time, a 5g.Each group is treated
3 weeks.
2. efficacy assessment standard
Symptom eliminates are substantially eliminated as effective, and symptom has been alleviated or mitigated as effective, and it is nothing to be not improved
Effect.
3. statistical method uses SPSS18.0 statistical analysis systems.If measured value is in normal distribution, represented with ± S,
If being in Non-Gaussian Distribution, represented with median；In the data of Non-Gaussian Distribution, give non-parametric rank sum test；Ranked data give
With non-parametric rank sum test.
4. result of the test
The test group result of table 1 is counted
The result of 2 control group of table 1 is counted
The result of 3 control group of table 2 is counted
In sum, composition of the invention is superior to control group 1 and control group 2 to the therapeutic effect of constipation and halitosis（P
<0.05）, illustrate that composition of the invention has functions that the toxin expelling that relaxes bowel, and black fungus powder and coconut husk charcoal are shared, and act on phase
It is auxiliary to coordinate, synergy has been played, optimum efficiency can be reached.
Embodiment 8
The bright universe of name king, man, 16 years old, people from Cangzhou City, habitual constipation took the purgatives medicine treatment constipation containing rheum officinale, warp
Often cause stomachache, after using this patent product instead（10 are each taken, constipation mitigates, it is continuous to use 15 days, produced without ill symptomses
Give birth to, and halitosis disappears substantially, and originally implication is heavier）.
Embodiment 9
Name Tian Yinchi, man, 76 years old, people from Hejian City of Hebei province, habitual constipation once took the purgatives medicine containing rheum officinale and controlled
Constipation is treated, constipation occurs repeatedly after drug withdrawal, and has gastrointestinal discomfort；After using this patent product instead（12 are each taken, continuously
Using 14 days, constipation disappeared, and was produced without ill symptomses）.
Embodiment 10
Name Jia Peng, man, 26 years old, people from Cangzhou City, habitual constipation, and also face, neck have severe acne, take and contain
The purgatives medicine treatment constipation of rheum officinale, often causes stomachache, after using this patent product instead（10 are each taken, constipation mitigates, continuously
Using 30 days, produced without ill symptomses, and acne mitigates）.
Embodiment 11
Name Wang Zhi grace, female, 32 years old, habitual constipation took the purgatives medicine treatment constipation containing rheum officinale, often causes abdomen
Bitterly, after using this patent product instead（12 are each taken, constipation mitigates, it is continuous to use 15 days, produced without ill symptomses）.
Embodiment 12
Wang Qingchun, female, 50 years old, habitual constipation took the purgatives medicine treatment constipation containing rheum officinale, often causes stomachache, intestines
Road is uncomfortable, after using this patent product instead（12 are each taken, is continuously mitigated using constipation in 15 days, produced without ill symptomses）.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as
Protection scope of the present invention.
Claims (4)
1. a kind of composition of the toxin expelling that can be relaxed bowel in intestinal absorption, it is characterised in that each component in described composition
Mass fraction is：Ultra-fine black fungus powder 45%, coconut husk charcoal 55%；Described ultra-fine black fungus powder is 10 microns with subordinate's fine powder.
2. composition according to claim 1, it is characterised in that described composition is tablet or capsule.
3. the preparation method of the tablet of any compositions of claim 1-2 or capsule, it is characterised in that including following step
Suddenly：According to the mass fraction described in claim 1, after ultra-fine black fungus powder and coconut husk charcoal are mixed, particle is made, loads enteric
It is coated with enteric coating material in capsule or after being pressed into tablet, drying, packing.
4. use of any described compositions of claim 1-2 in the medicine/food/health products for relaxing bowel toxin expelling are prepared
On the way.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410321729.9A CN104069302B (en) | 2014-07-08 | 2014-07-08 | A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410321729.9A CN104069302B (en) | 2014-07-08 | 2014-07-08 | A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104069302A CN104069302A (en) | 2014-10-01 |
| CN104069302B true CN104069302B (en) | 2017-06-30 |
Family
ID=51591168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410321729.9A Expired - Fee Related CN104069302B (en) | 2014-07-08 | 2014-07-08 | A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104069302B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110974919A (en) * | 2019-12-23 | 2020-04-10 | 湛江寸草制药有限公司 | Navel charcoal pill as medicine carrier for navel administration at Shenque acupoint as well as preparation method and application of navel charcoal pill |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011422A (en) * | 2006-02-05 | 2007-08-08 | 郑乐建 | Pharmaceutical/edible use of black fungus granule capsule adapted for constipation population |
-
2014
- 2014-07-08 CN CN201410321729.9A patent/CN104069302B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011422A (en) * | 2006-02-05 | 2007-08-08 | 郑乐建 | Pharmaceutical/edible use of black fungus granule capsule adapted for constipation population |
Non-Patent Citations (1)
| Title |
|---|
| 口服活性炭联合甘露醇在急性有机磷中毒中的应用;李军等;《中国媒炭工业医学杂志》;20130831;第16卷(第8期);第1305-1306页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104069302A (en) | 2014-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105342912A (en) | Traditional Chinese medicine toothpaste adopting grape seed matrix abrasive and preparation method of traditional Chinese medicine toothpaste | |
| CN104886255B (en) | Have effects that alleviate the probiotic food composition and food of bottleneck throat inflammation | |
| WO2007057924A1 (en) | Laxative composition on the basis of triphala | |
| DE102006056454A1 (en) | Taste-free, granular nutritional supplement, useful e.g. for preventing osteoporosis and psoriasis, contains synergistic combination of Spirulina, Chlorella and Lithothamnium algae | |
| CN103876141B (en) | A kind of composition of clearing lung-heat toxin expelling, its preparation method and application thereof | |
| CN102178217A (en) | Konjac-flour-containing mixture and preparation method thereof | |
| CN104069302B (en) | A kind of composition for the toxin expelling that can be relaxed bowel in intestinal absorption and its preparation method and application | |
| CN107951764A (en) | A kind of Chinese medicinal toothpaste for having effects that to prevent canker sore and repair mucous membrane of mouth | |
| CN101810700A (en) | Effervescent traditional Chinese medicine composition with function of freeing lung and relieving asthma and preparation method thereof | |
| CN110574894A (en) | nutritional meal replacement product capable of helping to eliminate vivotoxin and preparation method thereof | |
| CN109833352A (en) | The preparation process of Erhuang antidiarrheal enteric-coated micro-pill | |
| CN102133161B (en) | Anti-acne and skin-care product | |
| CN104187903A (en) | Artichoke freeze-dried powder and preparation method thereof | |
| CN105267108A (en) | Premna microphylla skin-protecting gel facing preparation | |
| CN104474369A (en) | Traditional Chinese medicine composition for treating stomach illness and preparation method thereof | |
| DE102014103832A1 (en) | Composition for the treatment of stomach disorders | |
| KR101652507B1 (en) | Herbal Medicine Composition and Pill for Ophthalmic Health | |
| CN106177269A (en) | The pharmaceutical composition of quick curing oral keritonocytes, preparation method and application | |
| KR101485261B1 (en) | Composition for rolling pills comprising adlay and rolling method thereof | |
| CN107115436A (en) | It is a kind of to treat medicine of cholecystitis and preparation method thereof | |
| CN109833305A (en) | Perfume connects the preparation process of antidiarrheal enteric-coated micro-pill | |
| WO2011089012A2 (en) | Carob bean meal (ceratonia siliqua) for the treatment of diarrhea | |
| CN102552884B (en) | Weight loss secret recipe of Zhuang medicine | |
| KR20170026851A (en) | A manufacturing method of salicornia europaea pills and the pillas made by same | |
| JP2004115420A (en) | Therapeutic agent for bronchial tube and pulmonary disease and food and beverage containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170630 Termination date: 20180708 |