CN104056007A - Sperm promoting capsule - Google Patents

Abstract

The invention provides a sperm promoting capsule, which has the functions of nourishing kidney and yin, as well as warming yang and promoting sperms, and has excellent effect for mainly treating small semen volume or liquefaction deficiency, azoospermia, dead sperms or oligozoospermia and other symptoms caused by deficiency of kidney-yin. The capsule is prepared from the following 32 raw medicinal materials by weight: raw rehmmania, prepared rehmmania, common yam rhizome, mulberry, cistanche, Chinese angelica, astragalus membranaceus, dodder, fructus lycii, raspberry, schisandra chinensis, glossy privet fruit, morinda officinalis, epimedium and the like. The sperm promoting capsule has an excellent effect for treating small semen volume or liquefaction deficiency, azoospermia, dead sperms or oligozoospermia and other symptoms caused by deficiency of kidney-yin, and does not have side effect on human bodies due to the purely natural traditional Chinese medicinal components.

Description

A kind of SHENGJING JIAONANG

Technical field

The present invention relates to a kind of medical science medicine section field, a kind of SHENGJING JIAONANG.

Technical background

At present, male infertility incidence rate is 10% left and right.Wherein simple wife's side factor is about 50%, and simple bridegroom's or husband's side factor is about 30%, and men and women total approximately 20%.Clinically male sterility is divided into sexual dysfunction and normal two classes of sexual function, it is sterile that the latter can be further divided into azoospermia, oligospermatism, azoospermia, asthenospermia disease and sperm count normality according to semen analysis result.

Male infertility is except congenital deformity of testis and dysplasia, and external potential hazard is Briefs, often easily out in the cold.The contraction of scrotum is that the temperature in order to regulate testis is spent left and right lower than body temperature 2, just testis only reaches optimum state lower than the secretion that is conducive to testosterone about body temperature 2 degree.Testosterone is the important substance that promotes spermatogenesis.The Briefs of current trend close-fitting vest, general design is above all double-deck, and scrotum and penis are bundled together, and of a specified duration causes under hip for a long time in the environment of high temperature humidity, becomes the hotbed that virus and bacteria grows.Under hip, high temperature humidity is the common andropathys' such as triggering male prostatitis, varicocele, seminal vesiculitis, eczema scrotum potential danger for a long time.Prostatitis, varicocele and seminal vesiculitis are male infertility common diseases.So expert advice penetrates the cloudy Briefs with pocket for male that wind is ventilative, heat radiation has been isolated more, keeps for a long time dry and comfortable ventilative heat radiation under hip.

The etiological classification of male sterility can be according to being divided into absolute sterility (azoospermia) and relative sterility (the few or motility of sperm of sperm quantity is low etc.) fertility, primary sterility and secondary sterility can be divided into by clinical manifestation, property after property before testis, testis and testis can be divided into by sexual organ's diseased region.The reason more complicated of male sterility, is now described below with regard to main cause.

(1) dysspermatism.

1. without sperm or spermacrasia

When in seminal fluid, sperm concentration is lower than 0.2 hundred million/ml the wife's side become pregnant chance reduce, during lower than 0.2 hundred million/ml, cause sterile.Thisly sterilely be divided into permanently and temporary, the former sees congenital testicualr development obstacle or testis, the serious pathological changes person of seminal vesicle; The latter is more common in sexual life overfrequency and causes once exhaustion of spermatogenesis, is generally oligospermia instead of completely without sperm.

2. sperm quality is poor

Unvital or too much (exceeding 20%) of Necrospermia in seminal fluid, or motility of sperm is very poor or teratospermia exceedes 30%, often can cause sterile.

3. seminal fluid physicochemical character is abnormal

Normal semen is congealed into gelatin very soon after penetrating, all liquefaction again in afterwards 15～30 minutes.If seminal fluid does not solidify after penetrating, or complete normal seminal vesicle or the prostate of pointing out of liquefaction has pathological changes.Antibacterial, viral infection reproductive tract also can cause the change of seminal fluid composition so that cause sterile.In seminal fluid, pathogenic bacterium are greater than 103/ml, and non-pathogenic bacteria is greater than 104/ml and all can causes sterile.

(2) dyszoospermia.

1. the own disease of testis

As atrophy of testis after tumor of testis, tuberculosis of testis, syphilis of testis, testis nonspecific inflammation, wound or torsion of spermatic cord, testis lack as etc., all can cause spermatogenesis obstacle, occur sterile.

2. chromosomal abnormality

Sex chromosomal abnormality can make sexual organ's poorly differentiateds such as testis, causes true property hermaphrodism and Klinefelter syndrome etc.Autosomal abnormalities can cause gonad and spermatogenic cell metabolism disorder.

3. spermatogenesis dysfunction

Long-term edible Oleum Gossypii semen can affect spermatogenesis Sperm autoimmunity, also can cause spermatogenesis dysfunction.

4. local patholoic change

As sickness influences such as recessive varicocele, huge hydrocele of tunica vaginalis the external environment of testis part, or the reason such as Yin Wendu, compressing causes sterile.

(3) sperm, ovum are in conjunction with obstacle.

1.Jing blocks in road

As lacking as deformities such as lockings of congenital semen deposition pipeline, surgical ligation deferent duct, the chronic inflammatory disease of smart road and surrounding tissue thereof etc.

2. retrograde ejaculation

As bladder neck once did operation or sustain damage or perform the operation after cicatricial contracture make urethra distortion shape, after bilateral lumbar sympathectomy or after rectal cancer abdomen perineal operation, the pudendal nerve infringement that diabetes cause, cyst of spermatic cord hypertrophy, and serious urethral stricture, some drugs, can cause that as epinephrine blocker etc. the sympathetic nerve function of domination bladder changes.

3. external genitalia is abnormal

As congenital penis is scarce, as too small in penis, androgynism, epispadias or under split, posteriority penis inflammation or damage, edema of scrotum, huge hydrocele of testis etc.

4. male sexual disorder

Sexual impotence, premature ejaculation, anejaculation etc.

(4) general factor.

1. spirit and environmental factors

Living environment flip-flop causes long-term psychentonia, carries out high-altitude, high temperature, super-strength work and is engaged in lonizing radiation work.

2. trophic factor

Serious malnutrition, VitAVitE deficiency disease, trace element is as zinc, manganese deficiency, calcium, disorders of phosphorus metabolism, hydrargyrum arsenic, lead, ethanol, nicotine, cotton seed wet goods toxicant chronic poisoning, chemotherapeutics treatment etc.

3. endocrinopathy

As growth hormone deficiency dwarfism, obesity, impotence generandi syndrome, adenohypophysis hypofunction, congenital gonad aplasia disease, congenital spermatogenesis can not syndrome, high prolactin antagonist disease, pituitary tumor or intracranial infection, maternal infuries etc.

1. semen analysis

To weigh the important and easy method of male fertility, the conventional normal value standard of China's seminal fluid is: semen volume 2～6ml/ time, liquefying time <30 minute, pH value is 7.2～8.0, sperm concentration normal value is >20 × 106/ml, sperm motility >=60%, vigor a level >25%, or vigor (a+b) >50%, sperm deformity <40%.By masturbation or sperm extractor, use special glass bottle, to collect without plastic cup or condom, the specimen transfer time does not exceed 1 hour, and temperature remains on 25～35 DEG C, and the ascetic time was advisable with 3～5 days.Because sperm number and sperm quality often change, therefore answer continuous review to average for 3 times.

2. urine and examination of prostatic fluid

Leucocyte in urine increases to point out and infects or prostatitis, and after ejaculation, urine examination finds that a large amount of sperms can consider retrograde ejaculation.Prostatic fluid microscopy leukocyte >10/HP, should do prostatic fluid antibacterial culturing.

3. Reproductive Endocrine Hormones is measured

Comprise the Reproductive Endocrine Hormones such as testosterone, testosterone T, LH, FSH.In conjunction with semen analysis and health check-up, can provide the reason of differentiating infertility.As all low in T, LH, FSH, diagnosable secondary hypogonadism; Simple T declines, and LH is normal or higher, and it is constitutional gonad function exhaustion that FSH increases diagnosable; T, LH are normal, and FSH raises and is diagnosed as selectivity spermatogenic epithelium functional defect; T, LH, FSH all increase, and are diagnosed as androgen tolerance syndrome.

4. antisperm antibody inspection

Immunological infertility accounts for 2.7%～4% of male infertility, and WHO recommends mixed antiglobulin reaction test (MAR method) and immune strain test.Not only can measure infertility Mr. and Mrs serum and secretions and whether have antisperm antibody, can also can measure these antibody be combined with sperm, and distinguishes which region of which kind of antibody and sperm and be combined.In the test of antiglobulin hybrid reaction, microemulsion drips with the percentage ratio of motile sperm combination and should be less than 10%.Immunity strain test, has the microemulsion of IgA or IgG antibody to drip and sample sperm Mixed culture pan coating, antibody will with the IgA of sperm surface or IgG combination.The key of this success of the test is that sperm should be to move.If immunity strain and exceed 50% motile sperm in conjunction with just thinking the result positive, in the case of the result positive, 75% the normal demonstration of sperm contains IgA or IgG.The explanation of these antibody test results should be very careful, because some patient is contained antibody, but do not affect its fertility.

In recent years, male infertility sickness rate progressively rises, and has brought misery to many families, allows a lot of male undertake heavy mental pressure.It is reported, the whole world approximately has 15% Mr. and Mrs sterile, and wherein male sterility accounts for 40%～50%.Nearly half a century, due to the impact of the factors such as environment, psychology, society, there is obvious downward trend in the quality and quantity of mankind spermatozoon, and male reproductive health is just being subject to serious threat.Man and wife lives together more than 1 year, does not take contraceptives, because bridegroom's or husband's side factor causes the not conceived person in the wife's side, is called male sterility.Sperm quality declines and may cause the danger that is difficult to conjecture to the mankind's quality, and for this reason, people conduct extensive research the factor that affects sperm quality, finds that global environmental pollution is the main cause that causes sperm quality to decline.The environmental factors that affects sperm quality comprises.

1, metallic element: verified have hydrargyrum, lead, cadmium etc. to the virose metal of reproduction tool.These heavy metals of Long Term Contact can cause sperm number decline, sperm concentration to reduce, motility of sperm reduces, an ejaculation volume reduces and the increase of teratospermia ratio.

2, pesticide and medicine: along with agriculture development, pesticide is more and more subject to people's attention the impact of sperm quality, such as dichlorvos, Malathion, methylene blue, the indigo-blue motor capacity that can affect sperm such as red, make that the number of sperm subtracts 8 less, form changes.

3, organic substance: a lot of organic substances have toxicity to sperm, as some harmful chemicals such as benzene, formaldehyde, food additive can hinder the born and vigor of sperm, even causes atrophy of testis.

4, gas (vehicle exhaust): research discovery, the people's eupyrene sperm ratio that often sucks vehicle exhaust obviously declines.

5, radiation: sexual cell is one of cell the most responsive to radiation, excess radiation can produce harmful effect to sperm.Electromagnetic wave, radioprotective, roentgen radiation x are all human sperm's killers, can make that spermatid is abnormal, anemia of pregnant woman's miscarriage and fetal development bad.

6, temperature: high temperature can produce infringement to testis, but how high temperature and time of exposing at this temperature how long, just can exert an influence to testis actually, still have arguement at present in educational circles.In zoopery, buck is placed in to 38.5 ° of C after lower 55 minutes, will decline its fertility.In actual life, male should avoid stopping in hot environment long-time as far as possible, as washes sauna bath and bath etc. with hot water.

7. medicine: anticancer, hormones, antibiotic etc can be damaged male gonad function, cause sperm quantity and Quality Down, or by affecting the endocrine function of gonad, cause sexual dysfunction.Medicine is subject to the factor impact such as kind, dosage, the course for the treatment of, patient's age of medicine on the impact of male fecundity.Generally the dosage of use medicine is larger, the course for the treatment of is longer, patient's age is less, more serious to the infringement of reproductive function, and the recovery needed time of reproductive function is also longer.

8. psychentonia reduces sperm count

Male is along with life and the quickening of work, cause some male to have no time to take exercises, passive protective physical fitness is declined, the quality of health also just worse and worse, especially male, life stress is large, long-term life of crossing this anxiety, and health is in emergent state, especially just cause stress hormone to have influence on Hypothalamus-pituitary-testis gonad axis, can make sperm quantity obviously decline.

Summary of the invention

In order to overcome the vacancy and deficiency of prior art, the invention provides a kind of SHENGJING JIAONANG, function tonification kidney yin, warming YANG spermatogenesis; Cure mainly deficiency of the kidney yin cause lack of quantity of spermatic fluid or liquefy bad, without diseases such as sperm, Necrospermia or few essences.

The present invention's medicine pharmacology and property of medicine used is as follows.

The Radix Rehmanniae:

Meridian distribution of property and flavor: sweet, cold; GUIXIN, liver, kidney channel;

Function cures mainly: clearing away heat and cooling blood, yin nourishing, promote the production of body fluid; Quench one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis for calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat.

Radix Rehmanniae Preparata:

Meridian distribution of property and flavor: sweet, tepor; Return liver, kidney channel;

Function cures mainly: nourishing YIN and supplementing blood, beneficial essence are filled out marrow; For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat quench one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.

Rhizoma dioscoreae:

Meridian distribution of property and flavor: sweet, flat; Return spleen, lung, kidney channel;

Function cures mainly: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission; For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung breath with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat quench one's thirst; Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating, for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.

Fructus Corni:

Meridian distribution of property and flavor: sour, puckery, tepor; Return liver, kidney channel;

Function cures mainly: liver and kidney tonifying, essence astringing and desertion stemming; For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse; Interior-heat is quenched one's thirst.

Fructus Mori:

Meridian distribution of property and flavor: sweet, sour, cold; GUIXIN, liver, kidney channel;

Function cures mainly: the YIN nourishing of enriching blood, promote the production of body fluid and moisturize; For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound are thirsty, interior-heat is quenched one's thirst, blood deficiency and constipation.

Herba Cistanches:

Meridian distribution of property and flavor: sweet, salty, warm; Return kidney, large intestine channel;

Function cures mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation; , dryness of the intestine constipation unable for sexual impotence, infertile, soreness of the waist and knees, muscles and bones.

Radix Angelicae Sinensis:

Meridian distribution of property and flavor: sweet, pungent, warm; Return liver, the heart, spleen channel;

Function cures mainly: enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow; For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.

Semen Cuscutae:

Meridian distribution of property and flavor: sweet, warm; Return liver,kidney,spleen warp;

Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal; Suffer from a deficiency of the kidney for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen rush down, externally treating leucoderma.

Fructus Lycii:

Meridian distribution of property and flavor: sweet, flat; Return liver, kidney channel;

Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight; For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat quench one's thirst, blood deficiency and yellow complexion, blurred vision be not clear.

Fructus Rubi:

Meridian distribution of property and flavor: sweet, sour, temperature; Return kidney, urinary bladder channel;

Function cures mainly: kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.For enuresis due to deficiency of the kidney, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea.

Fructus Schisandrae Chinensis:

Meridian distribution of property and flavor: temperature, acid, sweet; Return lung, the heart, kidney channel;

Function cures mainly: astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.Control the deficiency of the lung and breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.

Fructus Ligustri Lucidi:

Meridian distribution of property and flavor: sweet, bitter, cool; Return liver, kidney channel;

Function cures mainly: nourishing the liver and kidney, improving eyesight black hair; For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.

Radix Morindae Officinalis:

Meridian distribution of property and flavor: sweet, pungent, tepor; Return kidney, Liver Channel;

Function cures mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.

Herba Epimedii:

Meridian distribution of property and flavor: pungent, sweet, warm; Return liver, kidney channel;

Function cures mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; , rheumatic arthralgia soft for impotence and seminal emission, muscles and bones flaccidity, numbness contracture, climacteric hypertension.

The technical scheme that the present invention solves is: a kind of SHENGJING JIAONANG is to be formed by following weight parts raw material of Chinese medicine compatibility:

Radix Rehmanniae 9-15 part, Radix Rehmanniae Preparata 9-15 part, Rhizoma dioscoreae 9-15 part, Fructus Corni 9-15 part,

Fructus Mori 9-15 part, Herba Cistanches 9-15 part, the each 9-15 part of Radix Angelicae Sinensis, Radix Astragali 9-15

Semen Cuscutae 6-20 part, Fructus Lycii 6-20 part, Fructus Rubi 6-20 part, Fructus Schisandrae Chinensis 6-12 part,

Fructus Ligustri Lucidi 6-12 part, Radix Morindae Officinalis 6-12 part, Herba Epimedii 6-12,

Preparation method: medicine-feeding is dried and pulverized as smalls under 95 °, with capsule shells encapsulation, taking medicine before meal every day 3 times.

A kind of SHENGJING JIAONANG of the present invention is to be formed by following weight parts raw material of Chinese medicine compatibility:

15 parts, the Radix Rehmanniae, 15 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma dioscoreaes, 15 parts of Fructus Corni,

15 parts of Fructus Mori, 15 parts of Herba Cistanches, each 15 parts of Radix Angelicae Sinensis, the Radix Astragali 15,

20 parts of Semen Cuscutae, 20 parts of Fructus Lycii, 20 parts of Fructus Rubies, 12 parts of Fructus Schisandrae Chinensis,

12 parts of Fructus Ligustri Lucidi, 12 parts of Radix Morindae Officinaliss, Herba Epimedii 12;

The invention has the beneficial effects as follows: function tonification kidney yin, warming YANG spermatogenesis; Cure mainly deficiency of the kidney yin cause lack of quantity of spermatic fluid or liquefy bad, splendid without disease effects such as sperm, Necrospermia or few essences.

Tool of the present invention has the following advantages: this SHENGJING JIAONANG is fast to the splendid curative effect of male sterility effect, and natural Chinese medicine composition has no side effect to health.

Detailed description of the invention

Embodiment: male infertility, comprises sexual disorder, the infertility due to dysspermatism.We's clinical treatment 34 examples, cure 21 examples, account for 67.8%, and effective 11 examples, account for 32.4% invalid 2 examples, account for 5.8%.Must take medicine 3 months, hyperactivity of YANG due to deficiency of YIN sexual intercourse can not ejaculator, and it is splendid that available ZHIBAI DIHUANG WAN adds SHANZHIZI, Radix Gentianae, Radix Bupleuri, Rhizoma Cyperi, Fructus Liquidambaris, Semen Vaccariae texts.Note self conditioning, sexual life will have restraining, and it is optimistic that emotion is wanted, and daily life is regular, and diet is proper, and tobacco and wine will be given up, and such self nurses one's health, for tonic.Not only beneficial to aristogenesis, and the healthy of oneself is also beneficial to.

Above-described embodiment is preferably embodiment of the present invention, but embodiments of the present invention are not restricted to the described embodiments, and the present invention not part of detailed description is known technology.

Claims (2)

1. a SHENGJING JIAONANG, is characterized in that: formed by following weight parts raw material of Chinese medicine compatibility:

Radix Rehmanniae 9-15 part, Radix Rehmanniae Preparata 9-15 part, Rhizoma dioscoreae 9-15 part, Fructus Corni 9-15 part,

Fructus Mori 9-15 part, Herba Cistanches 9-15 part, the each 9-15 part of Radix Angelicae Sinensis, Radix Astragali 9-15,

Semen Cuscutae 6-20 part, Fructus Lycii 6-20 part, Fructus Rubi 6-20 part, Fructus Schisandrae Chinensis 6-12 part,

Fructus Ligustri Lucidi 6-12 part, Radix Morindae Officinalis 6-12 part, Herba Epimedii 6-12 part;

Preparation method: medicine-feeding is dried and pulverized as smalls under 95 °, with capsule shells encapsulation, taking medicine before meal every day 3 times.

2. a kind of SHENGJING JIAONANG according to claim 1, is characterized in that: formed by following weight parts raw material of Chinese medicine compatibility:

15 parts, the Radix Rehmanniae, 15 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma dioscoreaes, 15 parts of Fructus Corni,

15 parts of Fructus Mori, 15 parts of Herba Cistanches, each 15 parts of Radix Angelicae Sinensis, the Radix Astragali 15,

20 parts of Semen Cuscutae, 20 parts of Fructus Lycii, 20 parts of Fructus Rubies, 12 parts of Fructus Schisandrae Chinensis,

12 parts of Fructus Ligustri Lucidi, 12 parts of Radix Morindae Officinaliss, Herba Epimedii 12.