CN104055885A - Traditional Chinese medicine for treating neurodermatitis - Google Patents
Traditional Chinese medicine for treating neurodermatitis Download PDFInfo
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- CN104055885A CN104055885A CN201410233559.9A CN201410233559A CN104055885A CN 104055885 A CN104055885 A CN 104055885A CN 201410233559 A CN201410233559 A CN 201410233559A CN 104055885 A CN104055885 A CN 104055885A
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Abstract
The invention relates to a traditional Chinese medicine for treating neurodermatitis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of flax, 10 parts of poria with hostwood, 6 parts of large-leaved gentian, 11 parts of uncaria, 30 parts of nettle, 10 parts of ajuga nipponensis, 7 parts of tribulus shoots and 19 parts of dendrotrophe frutescens. Clinical experiments verify that the traditional Chinese medicine provided by the invention can safely and effectively treat neurodermatitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of neurodermatitis.
Background technology
Neurodermatitis claims again lichen chronicus simplex.It is the chronic dermatosis that turns to feature with paroxysmal skin pruritus and skin lichen.For common skin diseases, be more common in adult, child does not generally fall ill.
The oral patent medicine that is used for the treatment of at present neurodermatitis has: itching-relieving and ringworm-eliminating soup, GUIPI TANG and Western medicine cetirizine etc.But drug effect individual variation is too large, and therapeutic effect is undesirable, cannot thoroughly cure.
Medical material involved in the present invention is all recorded in " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of neurodermatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing neurodermatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine that is used for the treatment of neurodermatitis, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 15 parts of linum, 10 parts of Poria cum Radix Pinis, 6 parts of Radix Gentianae Macrophyllae, 11 parts of Ramulus Uncariae Cum Uncis, 30 parts of Herba Girardinlae Diversifoliaes, 10 parts of japanese bugle herbs, 7 parts of Herba tribulis, 19 parts of Ramulus et folium henslowiae frutescentiss.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor in January, 2011-2012 are collected altogether 76 examples between year May and are met inclusive criteria neurodermatitis patient, wherein matched group 38 examples, and 35 examples complete observation, and 3 examples come off; Treatment group 38 examples, 37 examples complete observation, and 1 example comes off, and the number of cases that comes off is less than 10%, has statistical significance.
For determining whether two groups of patient's physical data have comparability, before the sex to two groups of patients, age, the course of disease and treatment, state of an illness total mark etc. compares respectively, and its result is as follows:
Table 1 liang group sex ratio
Note: through X 2 test,
p=0.568>0.05, therefore two groups of Sex distribution there was no significant differences have comparability.
Table 2 liang group age ratio
Note: warp
tinspection,
p=0.497>0.05, therefore two groups of age distribution there was no significant differences have comparability.
Table 3 liang group course of disease comparison
Note: through X 2 test,
p=0.912>0.05, therefore two groups of course of disease distribution there was no significant differences have comparability.
State of an illness total mark comparison before table 4 liang group treatment
Note: through Maim-Whitney U inspection,
p=0.713>0.05, state of an illness total mark situation zero difference before two groups of treatments, has comparability.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times.Patient's further consultation in 2 weeks 1 time, a course for the treatment of 4 Mondays, carries out efficacy determination after the course for the treatment of.
Matched group oral hydrochloride cetirizine sheet, takes according to its description.Patient's further consultation in 2 weeks 1 time, a course for the treatment of 4 Mondays, carries out efficacy determination after the course for the treatment of.
Points for attention during two groups of treatments: rule of life during treatment, avoid the product that pungent stimulation, raw meat are sent out, give up habits of smoking and alcohol drinking.
2.2 observation items: the situation of change of Patients Before And After skin lesion and subjective symptoms is treated in main observation, comprise the situation of change of skin lesion area, skin lesion degree and pruritus degree.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
A: symptom score standard
" the new Chinese medicine guideline of clinical investigations " issued with reference to health ministry and " People's Republic of China's Chinese medicine industry standard disease of tcm Standardization of diagnosis and curative effect " are drafted.
1.: skin lesion area: no matter skin lesion size, it is 6 points that initial score value is all calculated.
0 point is reduced 90%-100%;
2 points are reduced 60%-89%;
4 points are reduced 30%-59%;
6 points are reduced <30%.
2. skin lesion degree: comprise pimple and lichenization degree.
0 point of nothing;
2 points have the tiny pimple of assembling tendency, without lichenization;
4 points pimple is intensive or fusion is in blocks, slight lichenization;
6 points of had significant proliferation plumpnesses, lichenizations or companion be rotten to the corn, ooze out, form a scab.
3. pruritus degree.
Before 0 point for the treatment of, after nothing or treatment, disappear;
2 points of prurituss once in a while, do not affect study and daily life, and <3 times/day scratches;
4 points of paroxysm prurituss, time light when heavy, impact study and daily life, <4-6 times/day scratches;
6 points of violent prurituss, are impatient at, and have a strong impact on study and daily life, and >6 times/day scratches.
B: efficacy assessment standard
Draft the curative effect of neurodermatitis with reference to State Administration of Traditional Chinese Medicine " TCM Dermatology disease Standardization of diagnosis and curative effect " (1995), be divided into healing, effective, effective and invalid.Clinical total effective rate comprises healing, effective and effective three kinds of situations.
Computational methods: total mark × 100% before therapeutic index=(the rear total mark of total mark-treatment before treatment)/treatment
Cure: therapeutic index >=90%;
Effective: 70%≤therapeutic index <90%;
Effective: 30%< therapeutic index <70%;
Invalid: therapeutic index <30%;
Total effective rate: (recovery from illness number of cases+effective number of cases+effectively number of cases)/total number of cases × 100%.
3.2 treatment statistical results are in table 5
Table 5 liang group curative effect comparison
Note: through X 2 test,
p=0.027<0.05, between two groups, total effective rate has significant difference, and treatment group is better than matched group.
Visible, the medicine that the present invention makes can safe and effective treatment neurodermatitis, and cure rate is high.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: linum 15 g, Poria cum Radix Pini 10 g, Radix Gentianae Macrophyllae 6 g, Ramulus Uncariae Cum Uncis 11 g, Herba Girardinlae Diversifoliae 30 g, japanese bugle herb 10 g, Herba tribuli 7 g, Ramulus et folium henslowiae frutescentis 19 g; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 450 mL,, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of neurodermatitis.Oral, after every bu morning, noon and afternoon breakfast, lunch and dinner, take half an hour.
Specific embodiment 2
Take: linum 15 g, Poria cum Radix Pini 10 g, Radix Gentianae Macrophyllae 6 g, Ramulus Uncariae Cum Uncis 11 g, Herba Girardinlae Diversifoliae 30 g, japanese bugle herb 10 g, Herba tribuli 7 g, Ramulus et folium henslowiae frutescentis 19 g; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of neurodermatitis.Oral, after every bu morning, noon and afternoon breakfast, lunch and dinner, take half an hour.
Specific embodiment 3
Take: linum 15 g, Poria cum Radix Pini 10 g, Radix Gentianae Macrophyllae 6 g, Ramulus Uncariae Cum Uncis 11 g, Herba Girardinlae Diversifoliae 30 g, japanese bugle herb 10 g, Herba tribuli 7 g, Ramulus et folium henslowiae frutescentis 19 g; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, then add appropriate dextrin and correctives, and to granulate according to this area common process, packaging, can make the granule that meets one day consumption of normal adult.
Be used for the treatment of neurodermatitis.Oral, after every bu morning, noon and afternoon breakfast, lunch and dinner, take half an hour.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of neurodermatitis, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 15 parts of linum, 10 parts of Poria cum Radix Pinis, 6 parts of Radix Gentianae Macrophyllae, 11 parts of Ramulus Uncariae Cum Uncis, 30 parts of Herba Girardinlae Diversifoliaes, 10 parts of japanese bugle herbs, 7 parts of Herba tribulis, 19 parts of Ramulus et folium henslowiae frutescentiss.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410233559.9A CN104055885A (en) | 2014-05-29 | 2014-05-29 | Traditional Chinese medicine for treating neurodermatitis |
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| CN201410233559.9A CN104055885A (en) | 2014-05-29 | 2014-05-29 | Traditional Chinese medicine for treating neurodermatitis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876121A (en) * | 2005-06-09 | 2006-12-13 | 熊明忠 | A medicinal wine capable of treating multiple diseases |
| CN102091270A (en) * | 2011-03-25 | 2011-06-15 | 路正平 | Medicament for treating neurodermatitis |
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2014
- 2014-05-29 CN CN201410233559.9A patent/CN104055885A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876121A (en) * | 2005-06-09 | 2006-12-13 | 熊明忠 | A medicinal wine capable of treating multiple diseases |
| CN102091270A (en) * | 2011-03-25 | 2011-06-15 | 路正平 | Medicament for treating neurodermatitis |
Non-Patent Citations (1)
| Title |
|---|
| 梁德权: "辨证分型治疗神经性皮炎46例", <<医学理论与实践>> * |
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Application publication date: 20140924 |