CN104042849A - Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof - Google Patents
Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof Download PDFInfo
- Publication number
- CN104042849A CN104042849A CN201410287835.XA CN201410287835A CN104042849A CN 104042849 A CN104042849 A CN 104042849A CN 201410287835 A CN201410287835 A CN 201410287835A CN 104042849 A CN104042849 A CN 104042849A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- preparation
- herba
- myrrha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to traditional Chinese medicinal liquid with a hemostatic effect and a preparation method thereof. The liquid is prepared from the following raw materials in parts by weight: 3-8 parts of myrrh, 10-18 parts of Chinese holly, 16-22 parts of pseudo-ginseng, 7-13 parts of artemisia anomala, 12-19 parts of scutellaria baicalensis, 10-14 parts of cuttlebone, 6-10 parts of circium japonicum, 7-15 parts of frankincense, 12-20 parts of schizonepeta, 13-21 parts of humifuse euphorbia herb and 7-14 parts of astragalus membranaceus. The traditional Chinese medicinal liquid has the characteristics of scientific formula, low cost, no toxic or side effect and the like, and can be used for achieving the effect of effective and quick hemostasis.
Description
Technical field
The present invention relates to a kind of herb liquid and preparation method with hemostasia effect, belonged to Chinese medicine field, be mainly used in containing otch and wound hemorrhage.
Background technology
Operation technique inevitably can cause hemorrhage from tremulous pulse, vein and blood capillary, and hemorrhage in operation can affect visual area, upsets surgical operation technique, severe patient threat to life.Hemostatic technique is one of core of operation basic fundamental, and along with the development of modern science and technology, hemostatic technique has developed into the mature technology system including medicine, equipment, anesthesia etc.Come in increasing to the research of Chinese medicine anastalsis, different from Western medicine hemostasis, the mechanism of Chinese medicine performance anastalsis is too many levels, by all kinds of means.Absorbable gelatin sponge is a kind of local hemostatic, belongs to hemostasis quasi drugs, is the sponge of white or the soft porous of light weight of micro-Huang, tool water absorption; Though through heavier rubbing, unlikely collapse broken.Absorbable gelatin sponge has large area water sucting surface, water absorption can reach the more than 30 times of this product volume, whole sponge is sticked in wound surface, can suck than the blood of the blood flow of the large several times of weight own, and as a mold, blood is solidified therein.This product itself can be by Absorption of antibody in 4～6 weeks, therefore can indwelling body cavity in or wound intracavity.Contact and do not produce undue scar tissue and bad fiberization with tissue.
Suck blood with in the pertinent literature of sponge existing, application publication number CN 102753203 A(application number 201080061630.X) Chinese patent literature a kind of hemostasis composite sponge is disclosed, it comprises biomaterial porous matrix and for strengthening described sponge for the adhering material that is applied tissue, while using described at least one surface of sponge be connected with the described tissue that is applied securely; A kind of method and their purposes in hemostasis of producing these sponges is also provided.Application publication number CN 103224645 A(application numbers 201310170559.4) Chinese patent literature a kind of sthptic sponge and application thereof are disclosed, this sthptic sponge is by modified starch of the prior art degeneration being finally prepared from through microwave treatment again.Application publication number CN 102475900 A(application numbers 201010553421.9) Chinese patent literature hemostatic material that a kind of Pseudobulbus Bletillae (Rhizoma Bletillae) makes and preparation method thereof is disclosed, water-soluble with Pseudobulbus Bletillae polysaccharose, make concentration 1-3% aqueous solution, under low temperature and vacuum drying, make.
At present, the prior art including above-mentioned patent documentation is remaining deficiency aspect solution wound bleeding, such as uncertain therapeutic efficacy is cut, with high costs etc.A kind of herb liquid with hemostasia effect is badly in need of in clinical practice.
Summary of the invention
For the present situation of the various bleedings of patient, the object of the present invention is to provide the herb liquid with hemostasia effect and the preparation method that can effectively stop blooding.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
There is the herb liquid of hemostasia effect, contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: Myrrha 3-8 part, Ilex purpurea Hassk.[I.chinensis Sims 10-18 part, Radix Notoginseng 16-22 part, Herba Artemisiae Anomalae 7-13 part, Radix Scutellariae 12-19 part, Endoconcha Sepiae 10-14 part, Radix Cirsii Japonici 6-10 part, Olibanum 7-15 part, Herba Schizonepetae 12-20 part, Herba Euphorbiae Humifusae 13-21 part, Rhizoma Paridis tetraphyllae 7-14 part.
The above-mentioned herb liquid with hemostasia effect, preferred scheme, contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: Myrrha 5-6 part, Ilex purpurea Hassk.[I.chinensis Sims 13-15 part, Radix Notoginseng 18-20 part, Herba Artemisiae Anomalae 9-11 part, Radix Scutellariae 15-16 part, Endoconcha Sepiae 11-13 part, Radix Cirsii Japonici 7-9 part, Olibanum 9-13 part, Herba Schizonepetae 14-18 part, Herba Euphorbiae Humifusae 16-18 part, Rhizoma Paridis tetraphyllae 9-12 part.
The above has the herb liquid of hemostasia effect, better preferred scheme, and contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: 6 parts of Myrrhas, 14 parts of Ilex purpurea Hassk.[I.chinensis Sims, 19 parts of Radix Notoginseng, 10 parts of Herba Artemisiae Anomalaes, 116 parts of Radix Scutellariaes, 12 parts of Endoconcha Sepiaes, 8 parts of Radix Cirsii Japonicis, 11 parts of Olibanums, 16 parts of Herba Schizonepetae, 17 parts of Herba Euphorbiae Humifusaes, 10 parts of Rhizoma Paridis tetraphyllae.
According to arbitrary described herb liquid above, its preparation methods steps is as follows:
(1) by weight ratio be the preferred 3:1 of 2-4:1() yellow wine and vinegar be mixed to get adjuvant, get clean Myrrha and Olibanum, adding weight is the adjuvant of 0.1-0.3 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, is placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 100-160 mesh sieve, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked to 3-6 hour with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 2-5 times of water gaging at every turn, respectively decoct 1-3 hour, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.6-0.8 to relative density, and sterile packaged obtains target product.
According to preparation method recited above, preferred scheme is that the consumption of step (1) adjuvant is Myrrha and Olibanum weight 0.2 times.
According to preparation method recited above, preferred scheme is that step (3) is crossed 120-140 mesh sieve (preferably 130 mesh sieves).
According to preparation method recited above, preferred scheme is that the soak time of step (4) vinegar is 4-5 hour (preferably 4.5 hours).
According to preparation method recited above, preferred scheme is that step (4) amount of water is doubly (preferably amount of water is 3.5 times) of 3-4.
According to preparation method recited above, preferred scheme is that step (4) decocts 2 hours.
According to preparation method recited above, preferred scheme is, it is 0.7 concentrated solution that step (4) is concentrated into relative density.
Have the herb liquid of hemostasia effect, the pharmacological effect of the each raw material of contained Chinese medicine is respectively:
Myrrha: be the gum resin of olive subject plant myrrh or Alan fort myrrh.Loose blood blood stasis removing, subduing swelling and relieving pain.Control and fall damage, incised wound, muscles and bones, all Tong ， of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Ilex purpurea Hassk.[I.chinensis Sims: bitter, puckery, cool.Heat-clearing and toxic substances removing; Promoting tissue regeneration and ulcer healing; Promoting blood circulation and hemostasis.Cure mainly cough due to lung-heat; Laryngopharynx swelling and pain; Dysentery; Diarrhoea; Biliary tract infection; Urinary tract infection; Angina pectoris; Burn and scald; Pyretic toxicity carbuncle; Ulcer of the lower limb; Leprelcosis; Eczema; Chilblain; Chap; Thromboangiitis obliterans; Traumatic hemorrhage.
Radix Notoginseng: sweet, micro-hardship, temperature.Return liver, lung, the heart, large intestine channel.Effect: hemostasis dissipating blood stasis, subduing swelling and relieving pain.Cure mainly haematemesis, hemoptysis, hematuria, has blood in stool, dysentery, metrorrhagia, postpartum hemorrhage, traumatic hemorrhage, injury from falling down, obstruction of qi in the chest and cardialgia, gastral cavity is coerced the long-pending piece of Tong ， mass in the abdomen of a specified duration, blood stasis amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, sore, carbuncle and painful swelling.
Herba Artemisiae Anomalae: be the wounded in the battle herb of Compositae sagebruss artemisia anomalas.The property of medicine: hardship, pungent, temperature.GUIXIN, liver, spleen channel.Effect: removing blood stasis dysmenorrhea, removing food stagnancy, hemostasia and detumescence.Cure mainly amenorrhea due to stagnation of blood, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen, abdominal pain due to retention of food, traumatic injury, incised wound is hemorrhage, hematuria, carbuncle poison, scalds.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Endoconcha Sepiae: be the inner shell of the multiple sepiellae seu sepiaes such as Sepiidae sepiella maindroni de Rochebrune, Sepia animal golden cuttlefish.The property of medicine: salty, puckery, temperature.Return liver, kidney channel.Effect: astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness sore.Cure mainly haematemesis, hematemesis, metrorrhagia, has blood in stool, epistaxis, wound hemorrhage, emission due to deficiency of the kidney spermatorrhea, leucorrhea with red and white discharge, has a stomachache noisy, belch pantothenic acid, eczema ulcer.
Radix Cirsii Japonici: be aerial parts or the root of Compositae artichoke plant Radix Cirsii Japonici.Sweet, micro-hardship, cool.GUIXIN, Liver Channel.Cooling blood for hemostasis, clots absorbing detumescence.Cure mainly haematemesis, spitting of blood, epistaxis, hematuria, has blood in stool, woman uterine bleeding, traumatic hemorrhage.
Olibanum: the oleo-gum-resin of oozing out for skin zones such as Burseraceae Boswellia plant Boswellia carterii, Bao Da Boswellia carterii, wild Boswellia carteriis.The property of medicine: pungent, bitter, temperature.GUIXIN, liver, spleen channel.Effect: invigorate blood circulation, circulation of qi promoting, pain relieving.Cure mainly trusted subordinate's pain, amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, traumatic injury stasis of blood pain, swollen ulcer drug, the sore being festered and unhealed.
Herba Schizonepetae: be the herb of Labiatae Schizonepeta tenuifolia platymiscium Herba Schizonepetae and many lobed leaf Herba Schizonepetae.The property of medicine: pungent, micro-hardship, tepor.Return lung, Liver Channel.Effect: dispel the wind, induce sweat, rash, hemostasis.Cure mainly cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, rubella, carbuncle, skin ulcer scabies, epistaxis, spits blood, has blood in stool, metrorrhagia, puerperal blood faints.
Herba Euphorbiae Humifusae: be the herb of euphorbia plant Radix seu Caulis Parthenocissi tricuspidatae or Herba Euphorbiae supinae.Pungent, flat.Return liver, large intestine channel.Heat clearing away, dampness removing, jaundice eliminating, hemostasis.Cure mainly dysentery, have loose bowels, jaundice, hemoptysis, spits blood, and hematuria, has blood in stool, metrorrhagia, agalactia, treating swelling and pain by traumatic injury and pathopyretic ulcer, the rotten skin ulcer of ecthyma.
Rhizoma Paridis tetraphyllae: be the rhizome of Liliaceae paris plant Paris bashanensis Wang et Tang.The property of medicine: hardship, pungent, temperature.Effect: expelling cold and dampness, removing obstruction in the collateral to relieve pain, hemostasia and promoting granulation.Cure mainly chronic arthralgia caused by cold-damp, chills and pain of the waist and kness, traumatic hemorrhage.
The invention has the beneficial effects as follows:
The herb liquid with hemostasia effect of the present invention, the prescription of contained Chinese medicine is according to modern Chinese medicine pharmacology, has passed through again clinical trial for many years, constantly gropes to form; Wherein Ilex purpurea Hassk.[I.chinensis Sims, Radix Notoginseng, Endoconcha Sepiae and Rhizoma Paridis tetraphyllae are hemostasis principal agent, Herba Artemisiae Anomalae, Radix Scutellariae, Radix Cirsii Japonici, Herba Schizonepetae and Herba Euphorbiae Humifusae are accessory drugs, the premium properties feature of crude drug and the complementary superposition of their performances are given full play to, there is promoting blood circulation to remove blood stasis, the several functions such as astringing to arrest bleeding, Myrrha and Olibanum have played the good balance property of medicine, have eliminated the function of the infringement of this Chinese medicine to health; Because medicine source is easy to get, so the present invention is cheap compared with other hemorrhage.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1there is the herb liquid of hemostasia effect, take off the primary raw material of stating weight proportion and be prepared from (getting 25g for every part): 3 parts of Myrrhas, 10 parts of Ilex purpurea Hassk.[I.chinensis Sims, 16 parts of Radix Notoginseng, 7 parts of Herba Artemisiae Anomalaes, 12 parts of Radix Scutellariaes, 10 parts of Endoconcha Sepiaes, 6 parts of Radix Cirsii Japonicis, 7 parts of Olibanums, 12 parts of Herba Schizonepetae, 13 parts of Herba Euphorbiae Humifusaes, 7 parts of Rhizoma Paridis tetraphyllae.
The preparation method of the above-mentioned herb liquid with hemostasia effect, step is as follows:
(1) yellow wine and the vinegar that are 2:1 by weight ratio are mixed to get adjuvant, get clean Myrrha and Olibanum, and adding weight is the adjuvant of 0.1 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, be placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 100 mesh sieves, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked 3 hours with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 2 times of water gagings at every turn, respectively decoct 1 hour, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.6 to relative density, and sterile packaged obtains target product.
typical case onepay certain, 36 years old, man, married, people from Nantong City, Han nationality, workman.When varnish furniture in May, 2013 at home, accidentally catch fire, furniture, clothes burning.Around neighbours fire-fight by water after finding, after approximately 10 minutes, are rescued by people, and sanity at that time, with ambulance delivers to hospital after being wrapped up by people with sheet.On patient back, palm, thigh front side skin, have phlysis, part is torn, and wound surface is red, alternate in vain, insensitive.Patient has carried out two upper limb and has cut crust and burrow allo-skin graft art under general anesthesia, and operation finished after 3 days, and in the time changing dressings, wound place is accidentally hemorrhage, and nurse dips embodiment 1 gained herb liquid with sponge, is gently pressed in operative incision place, and after 5 minutes, oozing of blood stops.
embodiment 2there is the herb liquid of hemostasia effect, take off the primary raw material of stating weight proportion and be prepared from (getting 5g for every part): 8 parts of Myrrhas, 18 parts of Ilex purpurea Hassk.[I.chinensis Sims, 22 parts of Radix Notoginseng, 13 parts of Herba Artemisiae Anomalaes, 19 parts of Radix Scutellariaes, 14 parts of Endoconcha Sepiaes, 10 parts of Radix Cirsii Japonicis, 15 parts of Olibanums, 20 parts of Herba Schizonepetae, 21 parts of Herba Euphorbiae Humifusaes, 14 parts of Rhizoma Paridis tetraphyllae.
The preparation method of the above-mentioned herb liquid with hemostasia effect, step is as follows:
(1) yellow wine and the vinegar that are 4:1 by weight ratio are mixed to get adjuvant, get clean Myrrha and Olibanum, and adding weight is the adjuvant of 0.3 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, be placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 160 mesh sieves, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked 6 hours with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 5 times of water gagings at every turn, respectively decoct 3 hours, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.8 to relative density, and sterile packaged obtains target product.
typical case twozhang, female 58 years old, married, people from Funing, Jiangsu, Han nationality, retired employees.Because of upper right abdominal distention and pain January, companion's jaundice first quarter moon is admitted to hospital.In this year the beginning of March, sense upper right abdomen persistence distending pain, to back part radiation, flatly increases the weight of when sleeping.After first quarter moon, there is sclera and xanthochromia, pruritus, stool is potter's clay color, and without heating, inappetence, feels sick, weak, become thin, and body weight idiopathy alleviates 5kg so far.Carrying out property of jaundice increases the weight of.Be diagnosed as cancer of biliary duct through examination in hospital, under general anesthesia, carried out Excision of Malignant Tumors operation.After operation, because nursing accidentally, operative incision splits, and occurs oozing of blood by a small margin, and nurse dips embodiment 2 gained herb liquids with sponge, is gently pressed in operative incision place, and after 7 minutes, oozing of blood stops.
embodiment 3there is the herb liquid of hemostasia effect, take off the primary raw material of stating weight proportion and be prepared from (getting 18g for every part): 5 parts of Myrrhas, 13 parts of Ilex purpurea Hassk.[I.chinensis Sims, 18 parts of Radix Notoginseng, 9 parts of Herba Artemisiae Anomalaes, 15 parts of Radix Scutellariaes, 11 parts of Endoconcha Sepiaes, 7 parts of Radix Cirsii Japonicis, 9 parts of Olibanums, 14 parts of Herba Schizonepetae, 16 parts of Herba Euphorbiae Humifusaes, 9 parts of Rhizoma Paridis tetraphyllae.
The preparation method of the above-mentioned herb liquid with hemostasia effect, step is as follows:
(1) yellow wine and the vinegar that are 2:1 by weight ratio are mixed to get adjuvant, get clean Myrrha and Olibanum, and adding weight is the adjuvant of 0.1 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, be placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 120 mesh sieves, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked 4 hours with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 3 times of water gagings at every turn, respectively decoct 1 hour, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.6 to relative density, and sterile packaged obtains target product.
embodiment 4there is the herb liquid of hemostasia effect, take off the primary raw material of stating weight proportion and be prepared from (getting 12g for every part): 6 parts of Myrrhas, 15 parts of Ilex purpurea Hassk.[I.chinensis Sims, 20 parts of Radix Notoginseng, 11 parts of Herba Artemisiae Anomalaes, 16 parts of Radix Scutellariaes, 13 parts of Endoconcha Sepiaes, 9 parts of Radix Cirsii Japonicis, 13 parts of Olibanums, 18 parts of Herba Schizonepetae, 18 parts of Herba Euphorbiae Humifusaes, 12 parts of Rhizoma Paridis tetraphyllae.
The preparation method of the above-mentioned herb liquid with hemostasia effect, step is as follows:
(1) yellow wine and the vinegar that are 4:1 by weight ratio are mixed to get adjuvant, get clean Myrrha and Olibanum, and adding weight is the adjuvant of 0.3 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, be placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 140 mesh sieves, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked 5 hours with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 4 times of water gagings at every turn, respectively decoct 3 hours, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.8 to relative density, and sterile packaged obtains target product.
typical case threeenemy, man, 32 years old, married, Han nationality, people from Shanghai City, worker.In the time that unify health check-up in unit in May, 2010, check out and suffer from thyroid cyst, doctor advised carries out cyst drainage and resection operation.After operation, because nursing accidentally, patient's cervical incision place is hemorrhage, and nurse dips embodiment 4 gained herb liquids with sponge, is gently pressed in operative incision place, and after 9 minutes, oozing of blood stops.
embodiment 5there is the herb liquid of hemostasia effect, take off the primary raw material of stating weight proportion and be prepared from (getting 15g for every part): 6 parts of Myrrhas, 14 parts of Ilex purpurea Hassk.[I.chinensis Sims, 19 parts of Radix Notoginseng, 10 parts of Herba Artemisiae Anomalaes, 16 parts of Radix Scutellariaes, 12 parts of Endoconcha Sepiaes, 8 parts of Radix Cirsii Japonicis, 11 parts of Olibanums, 16 parts of Herba Schizonepetae, 17 parts of Herba Euphorbiae Humifusaes, 10 parts of Rhizoma Paridis tetraphyllae.
The preparation method of the above-mentioned herb liquid with hemostasia effect, step is as follows:
(1) yellow wine and the vinegar that are 3:1 by weight ratio are mixed to get adjuvant, get clean Myrrha and Olibanum, and adding weight is the adjuvant of 0.2 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, be placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 130 mesh sieves, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked 4.5 hours with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 3.5 times of water gagings at every turn, respectively decoct 1.5 hours, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.7 to relative density, and sterile packaged obtains target product.
experimental examplein order to verify haemostatic effect of the present invention, carry out the present invention the animal model experiment with the herb liquid of hemostasia effect.
1, method for building animal model: white mice, after 0.2% tetracaine anesthesia, removes back hair, conventional skin degerming, the long stringer otch of a 1cm is cut respectively in both sides, back, cuts muscle simultaneously, deeply reaches abdominal cavity, then layer-by-layer suture muscle and skin, whole process simulation clinical operation process.
2, laboratory animal grouping: get the white mice that 156 body weight are 100-220g, be divided at random 6 groups, every group 26, be respectively and use the matched group of common sponge hemostasis and use sponge to dip the experimental group that embodiment 1-5 gained herb liquid stops blooding, when after operation, wound is hemorrhage, sponge is gently pressed in to bleeding part, records every white mice and stop blooding the time used.
3, haemostatic effect sees the following form:
Table 1
Analyze: from observed result, can find out, dip the successful that herb liquid of the present invention stops blooding and be better than common sponge, herb liquid hemostasis of the present invention is rapid-action, and without any side effects.
Claims (10)
1. the herb liquid with hemostasia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Myrrha 3-8 part, Ilex purpurea Hassk.[I.chinensis Sims 10-18 part, Radix Notoginseng 16-22 part, Herba Artemisiae Anomalae 7-13 part, Radix Scutellariae 12-19 part, Endoconcha Sepiae 10-14 part, Radix Cirsii Japonici 6-10 part, Olibanum 7-15 part, Herba Schizonepetae 12-20 part, Herba Euphorbiae Humifusae 13-21 part, Rhizoma Paridis tetraphyllae 7-14 part.
2. the herb liquid according to claim 1 with hemostasia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Myrrha 5-6 part, Ilex purpurea Hassk.[I.chinensis Sims 13-15 part, Radix Notoginseng 18-20 part, Herba Artemisiae Anomalae 9-11 part, Radix Scutellariae 15-16 part, Endoconcha Sepiae 11-13 part, Radix Cirsii Japonici 7-9 part, Olibanum 9-13 part, Herba Schizonepetae 14-18 part, Herba Euphorbiae Humifusae 16-18 part, Rhizoma Paridis tetraphyllae 9-12 part.
3. the herb liquid according to claim 1 with hemostasia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 6 parts of Myrrhas, 14 parts of Ilex purpurea Hassk.[I.chinensis Sims, 19 parts of Radix Notoginseng, 10 parts of Herba Artemisiae Anomalaes, 16 parts of Radix Scutellariaes, 12 parts of Endoconcha Sepiaes, 8 parts of Radix Cirsii Japonicis, 11 parts of Olibanums, 16 parts of Herba Schizonepetae, 17 parts of Herba Euphorbiae Humifusaes, 10 parts of Rhizoma Paridis tetraphyllae.
4. according to the preparation method of the arbitrary described herb liquid of claim 1-3, it is characterized in that, step is as follows:
(1) by weight ratio be the preferred 3:1 of 2-4:1() yellow wine and vinegar be mixed to get adjuvant, get clean Myrrha and Olibanum, adding weight is the adjuvant of 0.1-0.3 times of Myrrha and Olibanum weight, slightly moistening, after liquid is sucked, is placed in marmite, heat with slow fire, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, for subsequent use;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools for subsequent use;
(3) Ilex purpurea Hassk.[I.chinensis Sims, Radix Scutellariae, Radix Cirsii Japonici, Herba Euphorbiae Humifusae, Rhizoma Paridis tetraphyllae and step (2) gained is forged to Endoconcha Sepiae, pulverize, cross 100-160 mesh sieve, for subsequent use;
(4) Radix Notoginseng, Herba Artemisiae Anomalae and Herba Schizonepetae are soaked to 3-6 hour with vinegar, taking-up drains, mix with step (3) gained medicated powder, decoct with water 2 times, add 2-5 times of water gaging at every turn, respectively decoct 1-3 hour, then merge medicinal liquid, centrifugalize, gets the concentrated solution that supernatant concentration is 0.6-0.8 to relative density, and sterile packaged obtains target product.
5. preparation method according to claim 4, is characterized in that, the consumption of step (1) adjuvant is Myrrha and Olibanum weight 0.2 times.
6. preparation method according to claim 4, is characterized in that, step (3) is crossed 120-140 mesh sieve (preferably 130 mesh sieves).
7. preparation method according to claim 4, is characterized in that, the soak time of step (4) vinegar is 4-5 hour (preferably 4.5 hours).
8. preparation method according to claim 4, is characterized in that, step (4) amount of water is doubly (preferably amount of water is 3.5 times) of 3-4.
9. preparation method according to claim 4, is characterized in that, step (4) decocts 2 hours.
10. preparation method according to claim 4, is characterized in that, it is 0.7 concentrated solution that step (4) is concentrated into relative density.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410287835.XA CN104042849A (en) | 2014-06-25 | 2014-06-25 | Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410287835.XA CN104042849A (en) | 2014-06-25 | 2014-06-25 | Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104042849A true CN104042849A (en) | 2014-09-17 |
Family
ID=51496572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410287835.XA Pending CN104042849A (en) | 2014-06-25 | 2014-06-25 | Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104042849A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623350A (en) * | 2009-07-09 | 2010-01-13 | 刘宁 | Rapid hemostasis powder |
-
2014
- 2014-06-25 CN CN201410287835.XA patent/CN104042849A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623350A (en) * | 2009-07-09 | 2010-01-13 | 刘宁 | Rapid hemostasis powder |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104667244B (en) | A kind of Pediluvium composition for treating primary dysmenorrhea | |
| CN110051816A (en) | A kind of Chinese medicine composition of warming and activating meridian | |
| CN104208245A (en) | Traditional Chinese medicine medicated bath for tinea of feet and hands and preparation method thereof | |
| CN108619478A (en) | A kind of Chinese medicine preparation for treating treating rheumatic ostealgia | |
| CN105148210A (en) | Chinese medicine for treating cough and preparation method thereof | |
| CN104027539A (en) | Ordinary sterilization and disinfection sponge for anesthesia department and preparation method thereof | |
| CN105497972A (en) | Medical film used for treating burns and scalds and preparing method | |
| CN104042850A (en) | Postoperative disinfecting traditional Chinese medicine liquid and preparation method thereof | |
| CN104042849A (en) | Traditional Chinese medicinal liquid with hemostatic effect and preparation method thereof | |
| CN104043147B (en) | Anesthesia Department sucks blood by the preparation method of sponge | |
| CN104524030A (en) | Traditional Chinese medicine composition for treating deficient vital qi lingering pathogen type scleroderma | |
| CN104107366A (en) | Applying ointment used for treating tinea and preparation method thereof | |
| CN102743515B (en) | Traditional Chinese medicine ointment for treating burn and scald | |
| CN105125926A (en) | Medical powder for treating burns and scalds and preparation method of medical powder | |
| CN105687938A (en) | Traditional Chinese medicine preparation for anal fissure and preparation method thereof | |
| CN105963483A (en) | Traditional Chinese medicine ointment for promoting fracture healing and preparation method thereof | |
| CN105250533A (en) | Traditional Chinese medicine patch for treating postpartum blood stasis and preparation method thereof | |
| CN104958460A (en) | External lotion for treating scabies and preparation method | |
| CN105560582A (en) | Swelling eliminating and itch relieving ointment for treating chilblain and preparation method thereof | |
| CN103860698B (en) | A kind of pharmaceutical composition promoting wound healing and its preparation method and application | |
| CN105362436A (en) | Traditional Chinese medicine composition with efficacies of invigorating circulation of blood and eliminating pus | |
| CN104127765A (en) | Drops for treating skin tinea and preparation method thereof | |
| CN104587071A (en) | Traditional Chinese medicament for treating infantile blood-heat allergic purpura | |
| CN104383057A (en) | Paste for mainly treating traumatic injury and preparation method of paste for mainly treating traumatic injury | |
| CN104043048A (en) | Medicinal sponge for relieving incision pain after anesthesia disappears and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140917 |
|
| RJ01 | Rejection of invention patent application after publication |