CN104042769A

CN104042769A - Medicinal composition for treating prosopalgia

Info

Publication number: CN104042769A
Application number: CN201410253997.1A
Authority: CN
Inventors: 郭玉臣
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-06-10
Filing date: 2014-06-10
Publication date: 2014-09-17

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a medicinal composition for treating prosopalgia. The medicinal composition is prepared from the following traditional Chinese medicinal raw materials by weight: 10-45g of angelica, root, 10-30g of semen brassicae, 10-40g of tribulus terrestris, 10-45g of cordyceps sobolifera, 10-50g of arabic cowry shell, 2-6g of semen hyoscyami, 10-35g of rhizoma nardostachyos, 10-25g of rhinoceros horn and 10-50g of liquorice. Clinical treatments are performed on 120 patients with prosopalgia by utilizing the medicinal composition, 95 patients are cured, 21 patients are improved, and 4 patients are not improved; the cure rate is 79.2 percent, and the total effective rate is 96.7 percent. The medicinal composition is stable and exact in curative effect, high in cure rate and hard relapse, and does not have toxic or side effects.

Description

Treat prosopalgic pharmaceutical composition

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to one and treat prosopalgic pharmaceutical composition.

Background technology

Trigeminal neuralgia refers in facial nervi trigeminus areal area, occurs of short duration, the severe pain of outbreak repeatedly.It is the nervous system common diseases that a kind of cause of disease not yet understands.Belong to the traditional Chinese medical science " prosopodynia ", " headache ", " migraine ", categories such as " migraines ".

Doctor trained in Western medicine thinks that little contiguous abnormal vascular compressing of nervi trigeminus velamen is main cause.Trigeminal neuralgia is divided into two kinds of constitutional and Secondary cases.The primary trigeminal neuralgia cause of disease is understood at present not yet completely, and the cause of disease of secondary trigeminal neuralgia is by cerebellopontine angle tumor, Roots of trigeminal nerve and semilunar ganglion tumor, and vascular malformation, aneurysm, arachnoiditis, multiple sclerosis etc. cause.

The traditional Chinese medical science think trigeminal neuralgia be because be affected by the cold, due to the heresy and positive bright gastric heat of phlegm-fire, and taking ailment said due to cold or exposure as main.Because being subject to pathogenic wind toxic successor meridians, Yangming Channel network stagnates not all right, thus there is this card, or because emotion internal injury, liver are lost bar and reached, strongly fragrant and fire-transformation, due to pathogen upward attacking orifices in head.In addition because QI and blood cancer stagnant, block meridians and be pain.Common with liver and gall wind-fire and Yangming dryness-heat clinically.

At present, short for the course of disease, ailing lighter affected nerves of patients with trigeminal neuralgia, carbamazepine is the choice drug for the treatment of, but along with the increasing the weight of of the state of an illness, and Drug therapy can not mitigate the disease, and long-term taking can cause drug effect to weaken, and produces drug resistance, and negative interaction is obvious.Nervi trigeminus peripheral branch closed treating method is that medicine is comprised to dehydrated alcohol, phenol solution, doxorubicin, streptomycin etc. are expelled to the bone hole that nervi trigeminus branch passes through, effect and operator's technical merit and patient's severity extent are in close relations, and most patient recurrence within half a year to 2 year.

Summary of the invention

The object of the present invention is to provide a kind of stable curative effect definite, have no side effect, cure rate is high, be difficult for more afterwards the prosopalgic pharmaceutical composition for the treatment of of recurrence.

The technical solution adopted for the present invention to solve the technical problems is: treat prosopalgic pharmaceutical composition, raw material of Chinese medicine by following weight proportioning forms: Radix Angelicae Dahuricae 10-45g, Semen Sinapis Albae 10-30g, Fructus Atriplicis Sibiricae 10-40g, Periostracum cicadae 10-45g, Concha Erosariae seu Cypraeae 10-50g, Semen Hyoscyami 2-6g, Radix Et Rhizoma Nardostachyos 10-35g, Cornu rhinocerotis 10-25g, Radix Glycyrrhizae 10-50g.

Preferably, treat prosopalgic pharmaceutical composition, formed by the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 25g, Semen Sinapis Albae 10g, Fructus Atriplicis Sibiricae 30g, Periostracum cicadae 30g, Concha Erosariae seu Cypraeae 40g, Semen Hyoscyami 3g, Radix Et Rhizoma Nardostachyos 20g, Cornu rhinocerotis 10g, Radix Glycyrrhizae 40g.

Usage: be decocted in water for oral dose, 1 dose of every day, days 2 times, early, each 1 time of evening.

The pharmacologically active of the each raw material of Chinese medicine of the present invention is as follows:

The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature, return lung, stomach, large intestine channel, expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifies sensible, detumescence and apocenosis, cures mainly anemofrigid cold, headache, supraorbital bone pain, toothache, eye itching lacrimation, nasal obstruction, nasal sinusitis, wet chronic diarrhea, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, pruritus scabies, the venom contained.

Semen Sinapis Albae, odorless, acrid in the mouth, peppery, returns meridian of Hand-TAI YIN, warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.Cure mainly and reduce phlegm by drink; Mass dissipating and swelling eliminating.Main cough with asthma abundant expectoration; Fullness in the chest and hypochondriac pain; Numb limbs and tense tendons; Arthralgia; Multiple abscess caused by damp-phlegm; Carbuncle of yin nature toxic swelling.Control acute mastitis, breast carcinoma, mammary gland pain, tuberculosis, phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation vomiting, aphasia due to apoplexy, limbs arthralgia pain numbness, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.

Fructus Atriplicis Sibiricae, bitter, pungent, flat, return Liver Channel, suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.

Periostracum cicadae, sweet; Cold, cure mainly affection due to external wind and heat; Heating; Dizzy; Pharyngalgia; The single board computer rash initial stage; Rash goes out not smooth; Infantile convulsion; Conjunctival congestion and swelling pain; Pterygium; Night cry.

Concha Erosariae seu Cypraeae, salty, flat, return spleen, Liver Channel, heat clearing away, suppressing the hyperactive liver, calms the nerves, improving eyesight.Control pyretic toxicity corneal nebula, children's's macule enters order, frightened cautious sleeplessness.

Semen Hyoscyami, bitter in the mouth is pungent, and GUIXIN, stomach, Liver Channel have spasmolytic, pain relieving, calm the nerves, the effect of parasite killing.Control demented, acute infantile convulsion, migratory arthralgia faint pain, breath with cough, stomachache, chronic dysentery, chronic diarrhea, proctoptosis, toothache, carbuncle, malignant boil.

Radix Et Rhizoma Nardostachyos, acrid in the mouth, sweet, warm in nature, return spleen, stomach warp, regulating QI to relieve pain; Activating spleen and strengthening stomach, cures mainly abdominal distention; Anorexia; Toothache; Beriberi.

Cornu rhinocerotis, acid is salty, cold, GUIXIN, Liver Channel, heat clearing away, removing heat from blood, arresting convulsion, removing toxic substances.The cold pestilence pathogenic heat attacking blood system in febrile diseases that cures the wound, mania and irritation, agitation, delirium, macule, jaundice, spits blood, epistaxis, hematochezia, cellulitis toxic swelling.

Radix Glycyrrhizae, sweet, flat, return spleen, stomach, lung meridian, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The present invention has following beneficial effect: utilize pharmaceutical composition of the present invention to 120 routine affected nerves of patients with trigeminal neuralgia clinical treatments, cure 95 examples, effective 21 examples, invalid 4 examples, cure rate reaches 79.2%, total effective rate is 96.7%, and stable curative effect is definite, have no side effect, cure rate is high, be difficult for more afterwards recurrence.

Detailed description of the invention

Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.

Embodiment 1

Treat prosopalgic pharmaceutical composition, formed by the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 10g, Semen Sinapis Albae 20g, Fructus Atriplicis Sibiricae 40g, Periostracum cicadae 45g, Concha Erosariae seu Cypraeae 10g, Semen Hyoscyami 36g, Radix Et Rhizoma Nardostachyos 35g, Cornu rhinocerotis 25g, Radix Glycyrrhizae 20g.

Embodiment 2

Treat prosopalgic pharmaceutical composition, formed by the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 45g, Semen Sinapis Albae 10g, Fructus Atriplicis Sibiricae 20g, Periostracum cicadae 20g, Concha Erosariae seu Cypraeae 20g, Semen Hyoscyami 4g, Radix Et Rhizoma Nardostachyos 30g, Cornu rhinocerotis 15g, Radix Glycyrrhizae 10g.

Embodiment 3

Treat prosopalgic pharmaceutical composition, formed by the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 35g, Semen Sinapis Albae 30g, Fructus Atriplicis Sibiricae 10g, Periostracum cicadae 10g, Concha Erosariae seu Cypraeae 50g, Semen Hyoscyami 2g, Radix Et Rhizoma Nardostachyos 10g, Cornu rhinocerotis 20g, Radix Glycyrrhizae 50g.

Embodiment 4

Treat prosopalgic pharmaceutical composition, formed by the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 25g, Semen Sinapis Albae 10g, Fructus Atriplicis Sibiricae 30g, Periostracum cicadae 30g, Concha Erosariae seu Cypraeae 40g, Semen Hyoscyami 3g, Radix Et Rhizoma Nardostachyos 20g, Cornu rhinocerotis 10g, Radix Glycyrrhizae 40g.

Fang Zhong, Radix Angelicae Dahuricae expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifying are sensible; The Semen Sinapis Albae meridians that pass through, diaphoresis cold expelling; Fructus Atriplicis Sibiricae suppressing the hyperactive liver resolving depression, regulating QI to relieve pain; Periostracum cicadae arresting convulsion spasmolytic; Concha Erosariae seu Cypraeae suppressing the hyperactive liver is calmed the nerves; Semen Hyoscyami analgesic therapy, pain relieving; Radix Et Rhizoma Nardostachyos fragrance row is loose, warming spleen and stomach for dispelling cold, regulating QI to relieve pain; Cornu rhinocerotis heat clearing away, removing heat from blood, arresting convulsion, removing toxic substances; Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving spasm to stop pain, and the toxicity of separating altogether Semen Hyoscyami together with Cornu rhinocerotis.

Remarks and taboo: Semen Hyoscyami has certain toxicity, and the used time is noted dosage, and should not take for a long time.There is this taste medicine can being removed of the illness such as heart disease, hypertension.

Pharmaceutical composition of the present invention is to 120 routine affected nerves of patients with trigeminal neuralgia clinical treatment observations, and result statistics is as follows:

Patient's data: in 120 routine patients, women's 68 examples, male's 52 examples, at minimum 40 years old of age, maximum 67 years old, the course of disease was many at 3 months to 5 years, 54 years old mean age.

Symptoms: pain has suddenly, violent, show character shallow, that lancinate sample or burn sample; started by toggle area; or caused as taken food, speak, wash one's face, brushing teeth by some daily routines, completely normal twice interictal patient, when pain outbreak; conjunctival congestion; shed tears, face is rubescent, sialorrhea; the cause visible face spasm of pain repeatedly, does not have neural any damaged finding.

Therapeutic Method: pharmaceutical composition of the present invention is decocted in water for oral dose, 1 dose of every day, 2 times on the one, early, late sub-service.

Curative effect judging standard:

Cure: after treatment, pain disappears, and follows up a case by regular visits to and does not recur half a year;

Effective: after medication, pain disappears, follow up a case by regular visits to and in half a year, have recurrence, then medication is still effective;

Invalid: symptom is without obvious change.

Therapeutic outcome: cure 95 examples, effective 21 examples, invalid 4 examples, cure rate reaches 79.2%, and total effective rate is 96.7%.

Model case

Lee * *, female, 27 years old.More than the face ache moon of patient's private prosecution right side, and with flickering having a toothache, when outbreak, sensation cool a, cold extremities, increases the weight of day by day.The Western medicine such as oral carbamazepine, phenytoin Sodium can only respite.See its pale complexion, snivel, pale tongue, white and thin fur, stringy and tense pulse.The traditional Chinese medical science is thought affection by exopathogenic cold-wind, and this side's plus-minus, serve on 7 doses, transference cure.Remove Semen Hyoscyami, 10 doses of following the services, reach clinical cure, follow up a case by regular visits to 2 years, have no recurrence.

Claims

1. the prosopalgic pharmaceutical composition for the treatment of, is characterized in that, is made up of: Radix Angelicae Dahuricae 10-45g, Semen Sinapis Albae 10-30g the raw material of Chinese medicine of following weight proportioning, Fructus Atriplicis Sibiricae 10-40g, Periostracum cicadae 10-45g, Concha Erosariae seu Cypraeae 10-50g, Semen Hyoscyami 2-6g, Radix Et Rhizoma Nardostachyos 10-35g, Cornu rhinocerotis 10-25g, Radix Glycyrrhizae 10-50g.

2. the prosopalgic pharmaceutical composition for the treatment of as claimed in claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight proportioning: Radix Angelicae Dahuricae 25g, Semen Sinapis Albae 10g, Fructus Atriplicis Sibiricae 30g, Periostracum cicadae 30g, Concha Erosariae seu Cypraeae 40g, Semen Hyoscyami 3g, Radix Et Rhizoma Nardostachyos 20g, Cornu rhinocerotis 10g, Radix Glycyrrhizae 40g.