CN104023733A - 癌症的免疫原性治疗 - Google Patents
癌症的免疫原性治疗 Download PDFInfo
- Publication number
- CN104023733A CN104023733A CN201280059421.0A CN201280059421A CN104023733A CN 104023733 A CN104023733 A CN 104023733A CN 201280059421 A CN201280059421 A CN 201280059421A CN 104023733 A CN104023733 A CN 104023733A
- Authority
- CN
- China
- Prior art keywords
- immunomodulator
- cancer
- tumor
- therapy
- cell death
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Radiation-Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1120779.2 | 2011-12-02 | ||
| GBGB1120779.2A GB201120779D0 (en) | 2011-12-02 | 2011-12-02 | Cancer therapy |
| PCT/GB2012/052992 WO2013079980A1 (en) | 2011-12-02 | 2012-12-03 | Immunogenic treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104023733A true CN104023733A (zh) | 2014-09-03 |
Family
ID=45509083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280059421.0A Pending CN104023733A (zh) | 2011-12-02 | 2012-12-03 | 癌症的免疫原性治疗 |
Country Status (15)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114367060A (zh) * | 2022-01-13 | 2022-04-19 | 深圳大学 | 激光交变电场联合治疗仪 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11963716B2 (en) | 2010-07-19 | 2024-04-23 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
| GB201308325D0 (en) * | 2013-05-09 | 2013-06-19 | Immodulon Therapeutics Ltd | Cancer Therapy |
| FI3077041T3 (fi) | 2013-12-05 | 2024-10-16 | Rfemb Holdings Llc | Syövän immunoterapia radiotaajuisella sähköisellä solukalvon hajotuksella (rf-emb) |
| GB201322725D0 (en) * | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
| US11141216B2 (en) | 2015-01-30 | 2021-10-12 | Immunsys, Inc. | Radio-frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
| PL3319635T3 (pl) * | 2015-06-24 | 2021-10-25 | Immodulon Therapeutics Limited | Inhibitor punktu kontrolnego i prątek całokomórkowy do stosowania w terapii nowotworowej |
| RU2596505C1 (ru) * | 2015-07-02 | 2016-09-10 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) | Способ лечения онкологических больных цитотоксическими лимфоцитами |
| US10478194B2 (en) | 2015-09-23 | 2019-11-19 | Covidien Lp | Occlusive devices |
| CA3011460A1 (en) | 2016-01-15 | 2017-07-20 | Rfemb Holdings, Llc | Immunologic treatment of cancer |
| RU2018136347A (ru) * | 2016-04-14 | 2020-05-14 | Фелдрайх Каро Руиз Аб | Аппарат для радиационной терапии, включающий модуль ионизации и источник ультрафиолетового света |
| CA3058380A1 (en) | 2017-03-28 | 2018-10-04 | Emblation Limited | Stenosis treatment |
| US11173325B2 (en) | 2017-07-21 | 2021-11-16 | Varian Medical Systems, Inc. | Methods of use of ultra-high dose rate radiation and therapeutic agent |
| RU2664597C1 (ru) * | 2017-12-12 | 2018-08-21 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ комбинированного лечения больных первично операбельным и местно-распространенным неоперабельным раком молочной железы |
| MA54399A (fr) | 2018-12-03 | 2021-10-13 | Fusion Pharmaceuticals Inc | Radioimmunoconjugués et polythérapie à base d'inhibiteur de point de contrôle |
| US20220098578A1 (en) * | 2019-01-31 | 2022-03-31 | Bar Ilan University | Neoantigens created by aberrant-induced splicing and uses thereof in enhancing immunotherapy |
| US20230045616A1 (en) * | 2019-12-27 | 2023-02-09 | Nonprofit Organization North East Japan Study Group | Cancer treatment method and medicine |
| EP4376945A1 (en) * | 2021-07-27 | 2024-06-05 | Immodulon Therapeutics Limited | A mycobacterium for use in cancer therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003049751A1 (en) * | 2001-12-10 | 2003-06-19 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
| EP2010216A2 (en) * | 2006-03-24 | 2009-01-07 | Donald L. Morton | Mycobacterial immunotherapy for cancer treatment |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5207223A (en) | 1990-10-19 | 1993-05-04 | Accuray, Inc. | Apparatus for and method of performing stereotaxic surgery |
| EP0556248B1 (en) * | 1990-11-08 | 1997-06-25 | University College London | Mycobacterium as adjuvant for antigens |
| US5458125A (en) | 1994-01-28 | 1995-10-17 | Board Of Directors Of The Leland Standford Jr. University | Treatment planning method and apparatus for radiosurgery and radiation therapy |
| WO2000064476A2 (en) | 1999-04-23 | 2000-11-02 | Qlt Inc. | Immuno-adjuvant pdt treatment of metastatic tumors |
| US20020022032A1 (en) | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
| US7595048B2 (en) | 2002-07-03 | 2009-09-29 | Ono Pharmaceutical Co., Ltd. | Method for treatment of cancer by inhibiting the immunosuppressive signal induced by PD-1 |
| WO2004006837A2 (en) | 2002-07-12 | 2004-01-22 | The Johns Hopkins University | Mesothelin vaccines and model systems |
| US20090297540A1 (en) | 2005-10-21 | 2009-12-03 | Andrew Mellor | Induction of Indoleamine 2,3-Dioxygenase in Dendritic Cells by TLR Ligands and Uses thereof |
| US20080318252A1 (en) | 2007-04-23 | 2008-12-25 | Scott Kachlany | Rapid assay to test anti-cancer drugs under physiological conditions |
| GB0526033D0 (en) * | 2005-12-21 | 2006-02-01 | Bioeos Ltd | Method |
| WO2008110491A2 (en) | 2007-03-09 | 2008-09-18 | University Of Basel | Chemotherapy of neoplastic diseases using combinations of rapamycin and compounds modulating mtor pathway alone or in combination with heat |
| NZ600758A (en) | 2007-06-18 | 2013-09-27 | Merck Sharp & Dohme | Antibodies to human programmed death receptor pd-1 |
| PT2172211E (pt) * | 2008-10-01 | 2015-03-09 | Immatics Biotechnologies Gmbh | Composição de peptídeos associados a tumores e vacina anti -cancro relacionada para o tratamento de glioblastoma (gbm) e outros tipos de câncer |
| US8367075B2 (en) | 2010-07-02 | 2013-02-05 | Indian Institute Of Science | Synergistic combination and method thereof |
| US9114158B2 (en) * | 2011-03-09 | 2015-08-25 | The Johns Hopkins University | Compounds and methods of use in ablative radiotherapy |
| WO2012177624A2 (en) | 2011-06-21 | 2012-12-27 | The Johns Hopkins University | Focused radiation for augmenting immune-based therapies against neoplasms |
| GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
| EP2620159A1 (en) | 2012-01-24 | 2013-07-31 | Institut Pasteur | Improved cancer treatment by immunotherapy with bcg or antigenically related non-pathogenic mycobacteria |
| WO2013114367A2 (en) | 2012-02-01 | 2013-08-08 | Compugen Ltd. | C10rf32 antibodies, and uses thereof for treatment of cancer |
| US8617520B2 (en) | 2012-02-15 | 2013-12-31 | Immodulon Therapeutics Limited | Cancer therapy |
| GB201308325D0 (en) | 2013-05-09 | 2013-06-19 | Immodulon Therapeutics Ltd | Cancer Therapy |
| GB201322725D0 (en) | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
| EP3092004A4 (en) | 2014-01-06 | 2017-02-22 | The Trustees Of The University Of Pennsylvania | Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy |
| US10975112B2 (en) | 2015-06-16 | 2021-04-13 | Hangzhou Dac Biotech Co., Ltd. | Linkers for conjugation of cell-binding molecules |
| PL3319635T3 (pl) | 2015-06-24 | 2021-10-25 | Immodulon Therapeutics Limited | Inhibitor punktu kontrolnego i prątek całokomórkowy do stosowania w terapii nowotworowej |
| CN112672758A (zh) | 2018-06-25 | 2021-04-16 | 英摩杜伦治疗学公司 | 癌症治疗 |
-
2011
- 2011-12-02 GB GBGB1120779.2A patent/GB201120779D0/en not_active Ceased
-
2012
- 2012-12-03 SG SG11201402396XA patent/SG11201402396XA/en unknown
- 2012-12-03 MX MX2014006511A patent/MX2014006511A/es unknown
- 2012-12-03 BR BR112014012880A patent/BR112014012880A2/pt not_active IP Right Cessation
- 2012-12-03 CN CN201280059421.0A patent/CN104023733A/zh active Pending
- 2012-12-03 JP JP2014543984A patent/JP6085611B2/ja active Active
- 2012-12-03 KR KR1020147016935A patent/KR20140097419A/ko not_active Withdrawn
- 2012-12-03 US US14/361,992 patent/US20140356397A1/en not_active Abandoned
- 2012-12-03 AU AU2012343536A patent/AU2012343536B2/en active Active
- 2012-12-03 RU RU2014121335A patent/RU2014121335A/ru unknown
- 2012-12-03 EP EP12799260.0A patent/EP2785361B1/en active Active
- 2012-12-03 WO PCT/GB2012/052992 patent/WO2013079980A1/en not_active Ceased
- 2012-12-03 IN IN955MUN2014 patent/IN2014MN00955A/en unknown
- 2012-12-03 CA CA2857429A patent/CA2857429A1/en not_active Abandoned
-
2014
- 2014-05-29 IL IL232890A patent/IL232890A0/en unknown
-
2018
- 2018-12-19 US US16/225,028 patent/US11318193B2/en active Active
-
2020
- 2020-06-30 US US16/916,194 patent/US11554166B2/en active Active
-
2023
- 2023-01-13 US US18/154,177 patent/US20230149525A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003049751A1 (en) * | 2001-12-10 | 2003-06-19 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
| EP2010216A2 (en) * | 2006-03-24 | 2009-01-07 | Donald L. Morton | Mycobacterial immunotherapy for cancer treatment |
Non-Patent Citations (1)
| Title |
|---|
| MA X1等: ""Combination sonodynamic therapy with immunoadjuvant may be a promising new modality for cancer treatment"", 《MED HYPOTHESES》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114367060A (zh) * | 2022-01-13 | 2022-04-19 | 深圳大学 | 激光交变电场联合治疗仪 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190224294A1 (en) | 2019-07-25 |
| RU2014121335A (ru) | 2016-01-27 |
| IL232890A0 (en) | 2014-07-31 |
| US20140356397A1 (en) | 2014-12-04 |
| BR112014012880A2 (pt) | 2017-06-13 |
| MX2014006511A (es) | 2014-12-05 |
| IN2014MN00955A (cg-RX-API-DMAC7.html) | 2015-04-24 |
| AU2012343536A1 (en) | 2014-06-05 |
| WO2013079980A1 (en) | 2013-06-06 |
| EP2785361A1 (en) | 2014-10-08 |
| JP6085611B2 (ja) | 2017-02-22 |
| AU2012343536B2 (en) | 2017-08-24 |
| JP2014533743A (ja) | 2014-12-15 |
| GB201120779D0 (en) | 2012-01-11 |
| US11318193B2 (en) | 2022-05-03 |
| US11554166B2 (en) | 2023-01-17 |
| EP2785361B1 (en) | 2018-11-28 |
| US20230149525A1 (en) | 2023-05-18 |
| NZ624994A (en) | 2016-10-28 |
| CA2857429A1 (en) | 2013-06-06 |
| US20200338181A1 (en) | 2020-10-29 |
| SG11201402396XA (en) | 2014-10-30 |
| KR20140097419A (ko) | 2014-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140903 |
|
| WD01 | Invention patent application deemed withdrawn after publication |