CN104013781A - Traditional Chinese medicine (TCM) powder for treating varicocele - Google Patents

Traditional Chinese medicine (TCM) powder for treating varicocele Download PDF

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Publication number
CN104013781A
CN104013781A CN201410296790.2A CN201410296790A CN104013781A CN 104013781 A CN104013781 A CN 104013781A CN 201410296790 A CN201410296790 A CN 201410296790A CN 104013781 A CN104013781 A CN 104013781A
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China
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parts
tcm
varicocele
powder
chinese medicine
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CN201410296790.2A
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陈晓明
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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Publication of CN104013781A publication Critical patent/CN104013781A/en
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Abstract

The invention provides traditional Chinese medicine (TCM) powder for treating varicocele. The TCM powder is characterized by being prepared from the following TCM raw materials in parts by weight: 5-15 parts of pseudo-ginseng, 10-20 parts of draconis resin, 20-40 parts of scorpions, 20-40 parts of centipedes, 20-40 parts of woodlice, 20-40 parts of leeches, 20-40 parts of pangolin scales, 10-30 parts of cassia bark, 30-60 parts of inner membrane of chicken gizzard, 80-150 parts of Chinese yam, 20-40 parts of medicinal cyathula root and 20-40 parts of armadillidium vulgare. The TCM powder has the advantages of exact curative effects on varicocele, low treatment cost, simple and convenient preparation and taking methods, no side effects, low relapse rate after cure, and the like.

Description

A kind of Chinese powder medicine for the treatment of varicocele
Technical field:
The present invention relates to Chinese medicine technical field, particularly a kind of Chinese powder medicine for the treatment of varicocele.
Background technology:
Varicocele refers to that pampiniform plexus interior in spermatic cord is because of backflow obstruction, and the tortuous expansion, the elongation and tortuous that occur.Be between twenty and fifty common disease, refer to because spermatic vein blood stagnation causes spermatic cord pampiniform plexus (vein blood vessel clump) vasodilation, tortuous and elongated.This disease sickness rate in common man is about 20%, and cause the reasons such as local temperature rising, anoxia, the change of pH value, toxicant delay to cause sperm quantity to reduce due to varicocele, the rising of motility of sperm decline and teratospermia ratio, thereby the fertility that has reduced male, causes male sterility.Doctor trained in Western medicine only has surgical resection or reparation.But wound is large, painful large, recovery time is long, and expense is high, and Postoperative recurrent rate is higher, wants careful selection for the patient who there is no fertility, because recurrence after operation possibility symptom is more serious.
Summary of the invention:
The present invention is exactly in order to overcome deficiency of the prior art, provide that a kind for the treatment of for varicocele has that determined curative effect, medical expense are cheap, preparation and instructions of taking easy, and it is little to have no side effect, and controls the Chinese powder medicine that recurrence rate after healing is low.
The invention provides following technical scheme:
Treat a Chinese powder medicine for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Notoginseng 5-15 part, Sanguis Draxonis 10-20 part, Scorpio 20-40 part, Scolopendra 20-40 part, ground beetle 20-40 part, Hirudo 20-40 part, Squama Manis 20-40 part, Cortex Cinnamomi 10-30 part, Endothelium corneum 30-60 part, Rhizoma Dioscoreae 80-150 part, Radix Cyathulae 20-40 part, Armadillidium 20-40 part.
Formula optimization is:
10 parts of Radix Notoginseng, 15 parts of Sanguis Draxonis, 30 parts of Scorpios, 30 parts of Scolopendras, 30 parts of ground beetles, 30 parts of Hirudos, 30 parts of Squama Manis, 20 parts of Cortex Cinnamomis, 50 parts of Endothelium corneum, 100 parts of Rhizoma Dioscoreaes, 30 parts of Radix Cyathulaes, 30 parts of Armadillidiums.
Preparation method:
Get by weight ratio above-mentioned various raw material of Chinese medicine, screening-elutriation-after drying, be together ground into 100-150 order fine powder, after sterilizing, every 6 grams of independent packagings.Take medicine twice every day, each bag, taking medicine continuously one week is a course for the treatment of.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
Radix Notoginseng: sweet and slightly bitter taste, warm in nature, return liver, stomach warp, be used as medicine with root, root stock.There is dissipating blood stasis hemostasis, the effects such as subduing swelling and relieving pain.Be usually used in various inside and outside hemorrhage, breast ventral spine pain, the diseases such as tumbling and swelling.This product can be tightened and improved Coronary microcirculation significantly.In addition; also there is blood vessel dilating, analgesia, resisting fatigue, raising learning and memory ability, anti-inflammatory, can make too high or too low immunoreation return to normally, but the effects such as the not normal immunoreation of interference body, antitumor, defying age, antioxidation, reduction blood fat and cholesterol and the liver protecting.
Sanguis Draxonis: sweet in the mouth, salty, property is flat.Enter the heart, liver, spleen channel.There is promoting blood circulation to remove blood stasis, analgesic therapy, external hemostasia and promoting granulation, the effects such as sore.Be usually used in congestion amenorrhea, dysmenorrhea, postpartum stagnation, lump in the abdomen mass in the abdomen, breast ventral spine pain, traumatic injury, congestion swells and ache, traumatic hemorrhage, the diseases such as ulcer being unable to heal.Sanguis Draxonis water decoction-alcohol sedimentation liquid (1:1) 0.1ml in vitro tests, is added in 0.5ml platelet rich plasma, and the platelet aggregation of ADP induction is had to inhibitory action.
Scorpio: acrid in the mouth, property is flat; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, dispersing pathogen accumulation, the effects such as removing obstruction in the collateral to relieve pain.Be usually used in infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, the diseases such as scrofula.
Scolopendra: acrid in the mouth, warm in nature; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, merit poison eliminating stagnation, the effects such as removing obstruction in the collateral to relieve pain.Be usually used in infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, the diseases such as venom.
Ground beetle: salty in the mouth, cold in nature; Slightly poisonous.Return Liver Channel.There is removing blood stasis with potent drugs blood, the effects such as reuniting the fractured tendons and bones.Be usually used in injured bone, blood stasis amenorrhea, the diseases such as lump in the abdomen mass in the abdomen.In " herbal classic ", record this product: " main trusted subordinate's cold and heat are washed, accumulation of blood lump in the abdomen, broken hard, hematochezia closes ".
Hirudo: salty in the mouth, hardship, property is flat; Slightly poisonous.Return Liver Channel.There is removing blood stasis, removing blood stasis, the effect such as stimulate the menstrual flow.Be usually used in lump in the abdomen mass in the abdomen, blood stasis amenorrhea, the diseases such as injury from falling down.In this product, institute's hirudin is up to now, the strongest thrombin special efficacy inhibitor in the world.In addition, this product also has expansion blood capillary and increases the hemorrhage effect of Denging.
Squama Manis: and the first sheet of Squama Manis, this product salty in the mouth, cold nature.Return liver, stomach warp.There is the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, the effects such as expel wind to dredge collateral.Be usually used in Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, the diseases such as numbness contracture.Experiment shows: the decocting liquid of Squama Manis sheet has the effect of obvious prolongation rat clotting time and reduces the effect of rat blood viscosity.In addition also there is, the effect of antiinflammatory.
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.There is the fire of benefit supporing yang, let the fire back to its origin, dispersing cold for relieving pain, the effects such as promoting blood circulation to restore menstrual flow.Be usually used in for sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, the diseases such as dysmenorrhea.Experiment shows: the cinnamic aldehyde containing in Cortex Cinnamomi is to the obvious sedation of mice Ke; All there is cooling effect to mice normal body temperature and by the artificial fever that typhoid fever, paratyphoid fever mixed vaccine cause; There is hypotensive effect; Oleum Cinnamomi has powerful bactericidal action.
Endothelium corneum: sweet in the mouth, property is flat.Return spleen, stomach, small intestinal, urinary bladder channel.There is invigorating the stomach and promoting digestion, the effects such as arresting seminal emission.Be usually used in food stagnation and do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, the diseases such as seminal emission.After oral Endothelium Corneum Gigeriae Galli, gastric secretion, acidity and eupepsy are all shown in and increase, and wherein the increase of eupepsy appearance is slower, remains also more of a specified duration.After taking medicine, gastric motor function obviously strengthens, and shows the prolongation of stomach moving period and the enhancing of peristalsis, due to the enhancing of stomach motion, therefore gastric emptying rate is also accelerated greatly.In Endothelium Corneum Gigeriae Galli itself, do not contain any digestive enzyme, its impact on stomachial secretion and motion, produces after not taking medicine immediately, and must be through after a while, therefore certain humoral factor that its effect enters in blood after digested by medicine causes.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.There is spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the effects such as the kidney invigorating arresting seminal emission.Be usually used in insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, the deficiency-heat disease such as quench one's thirst.Rhizoma Dioscoreae is rich in multivitamin, aminoacid and mineral, can prevent and treat Human Lipid Metabolism abnormal, and arteriosclerosis, to safeguarding that insulin normal function also has certain effect, there is enhancing body immunity, beneficial heart and tranquilizing mind, rather cough the health-care effects such as Dingchuan, slow down aging; Improve the immunity of body, strengthen the phagocytosis of macrophage.In addition, Rhizoma Dioscoreae water extraction liquid also can be eliminated urine protein, mutant cell is had to the effect that suppresses generation.
Radix Cyathulae: sweet in the mouth, micro-hardship, property is flat.Return liver, kidney channel.There is eliminating blood stasis and inducing menstruation, easing joint movement, the effects such as inducing diuresis for treating stranguria syndrome.Be usually used in amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, the diseases such as injury from falling down.
Armadillidium: sour in the mouth, warm in nature, nontoxic.Return Liver Channel, kidney channel.There is removing blood stasis, diuretic, removing toxic substances, the effects such as pain relieving.Be usually used in chronic malaria malaria with splenomegaly, amenorrhea lump in the abdomen, urinary obstruction, infantile convulsion locked jaw, ability to speak pain, the diseases such as all skin ulcers of thrush.
The invention has the advantages that:
The present invention for the treatment of varicocele have that determined curative effect, medical expense are cheap, preparation and instructions of taking easy, and it is little to have no side effect, and controls the advantages such as recurrence rate after healing is low.
Detailed description of the invention:
Embodiment 1:
Treat a Chinese powder medicine for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 10 parts of Radix Notoginseng, 15 parts of Sanguis Draxonis, 30 parts of Scorpios, 30 parts of Scolopendras, 30 parts of ground beetles, 30 parts of Hirudos, 30 parts of Squama Manis, 20 parts of Cortex Cinnamomis, 50 parts of Endothelium corneum, 100 parts of Rhizoma Dioscoreaes, 30 parts of Radix Cyathulaes, 30 parts of Armadillidiums.
Preparation method:
Get by weight ratio above-mentioned various raw material of Chinese medicine, screening-elutriation-after drying, be together ground into 100-150 order fine powder, after sterilizing, every 6 grams of independent packagings.Take medicine twice every day, each bag, taking medicine continuously one week is a course for the treatment of.
Embodiment 2:
Treat a Chinese powder medicine for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 8 parts of Radix Notoginseng, 10 parts of Sanguis Draxonis, 20 parts of Scorpios, 20 parts of Scolopendras, 20 parts of ground beetles, 20 parts of Hirudos, 20 parts of Squama Manis, 10 parts of Cortex Cinnamomis, 30 parts of Endothelium corneum, 80 parts of Rhizoma Dioscoreaes, 20 parts of Radix Cyathulaes, 20 parts of Armadillidiums.
Preparation method:
Get by weight ratio above-mentioned various raw material of Chinese medicine, screening-elutriation-after drying, be together ground into 100-150 order fine powder, after sterilizing, every 6 grams of independent packagings.Take medicine twice every day, each bag, taking medicine continuously one week is a course for the treatment of.
Embodiment 3:
Treat a Chinese powder medicine for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 15 parts of Radix Notoginseng, 18 parts of Sanguis Draxonis, 35 parts of Scorpios, 38 parts of Scolopendras, 35 parts of ground beetles, 38 parts of Hirudos, 38 parts of Squama Manis, 25 parts of Cortex Cinnamomis, 55 parts of Endothelium corneum, 135 parts of Rhizoma Dioscoreaes, 35 parts of Radix Cyathulaes, 40 parts of Armadillidiums.
Preparation method:
Get by weight ratio above-mentioned various raw material of Chinese medicine, screening-elutriation-after drying, be together ground into 100-150 order fine powder, after sterilizing, every 6 grams of independent packagings.Take medicine twice every day, each bag, taking medicine continuously one week is a course for the treatment of.
Toxicity test:
Use formula in embodiment 1 make powder to mice by 0.8g, 1.5g/3.0g crude drug/kg continuous use 15 weeks (every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as the hair of Chinese medicine preparation of the present invention to rat, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat all has no significant effect, internal organs naked eyes do not find that difference changes and histological examination result shows, medication 15 weeks and drug withdrawal are after 3 weeks, and the each internal organs of rat are all without obviously changing.Visible Chinese powder medicine of the present invention to rat long-term prescription after toxicity little, after drug withdrawal, there is no difference reaction, application safety yet.
Model case:
1, patient Liu, man, 18 years old.Varicocele more than 1 year, has heavy and falling inflation sense, and when walking, pain increases the weight of, and does not often feel well, once suffer from cold, falling inflation sense adds huge, takes after the course for the treatment of of the present invention, and pain has obvious reduction, after 3 courses for the treatment of of taking medicine again, recovers.
2, Zheng, man, 21 years old.Varicocele 2 years, has heavy and falling inflation sense, to groin radiation, when walking and work, increases the weight of, and after flat bed rest, alleviates, and impact is had a rest and work.Take after two courses for the treatment of of the present invention, pain has obvious reduction, after 4 courses for the treatment of of taking medicine again, recovers.

Claims (2)

1. treat a Chinese powder medicine for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Notoginseng 5-15 part, Sanguis Draxonis 10-20 part, Scorpio 20-40 part, Scolopendra 20-40 part, ground beetle 20-40 part, Hirudo 20-40 part, Squama Manis 20-40 part, Cortex Cinnamomi 10-30 part, Endothelium corneum 30-60 part, Rhizoma Dioscoreae 80-150 part, Radix Cyathulae 20-40 part, Armadillidium 20-40 part.
2. according to a kind of Chinese powder medicine for the treatment of varicocele described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 10 parts of Radix Notoginseng, 15 parts of Sanguis Draxonis, 30 parts of Scorpios, 30 parts of Scolopendras, 30 parts of ground beetles, 30 parts of Hirudos, 30 parts of Squama Manis, 20 parts of Cortex Cinnamomis, 50 parts of Endothelium corneum, 100 parts of Rhizoma Dioscoreaes, 30 parts of Radix Cyathulaes, 30 parts of Armadillidiums.
CN201410296790.2A 2014-06-28 2014-06-28 Traditional Chinese medicine (TCM) powder for treating varicocele Pending CN104013781A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113118A1 (en) * 2007-03-16 2008-09-25 Medcina Group Pty Ltd Compositions and methods for treating male infertility
CN103251905A (en) * 2013-05-17 2013-08-21 林寿江 Chinese herbal compound composition for treating varicosity
CN103536869A (en) * 2013-09-25 2014-01-29 王纯治 Chinese medicinal prescription for treating varicocele
CN103656081A (en) * 2012-09-17 2014-03-26 许建明 Traditional Chinese medicine formula for treating varicosity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113118A1 (en) * 2007-03-16 2008-09-25 Medcina Group Pty Ltd Compositions and methods for treating male infertility
CN103656081A (en) * 2012-09-17 2014-03-26 许建明 Traditional Chinese medicine formula for treating varicosity
CN103251905A (en) * 2013-05-17 2013-08-21 林寿江 Chinese herbal compound composition for treating varicosity
CN103536869A (en) * 2013-09-25 2014-01-29 王纯治 Chinese medicinal prescription for treating varicocele

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
庞保珍等: "中医药治疗精索静脉曲张不育的研究进展", 《中国性科学》 *
项平 等: "《实用验方大全》", 30 November 2004, 江苏科学技术出版社 *

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Application publication date: 20140903