CN104013757A - Traditional Chinese medicine for external use for treating gastric cancer - Google Patents
Traditional Chinese medicine for external use for treating gastric cancer Download PDFInfo
- Publication number
- CN104013757A CN104013757A CN201410272848.XA CN201410272848A CN104013757A CN 104013757 A CN104013757 A CN 104013757A CN 201410272848 A CN201410272848 A CN 201410272848A CN 104013757 A CN104013757 A CN 104013757A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- external application
- principal agent
- accessory drugs
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine for external use for treating gastric cancer. The traditional Chinese medicine for external use is obtained by blending a main drug with an adjuvant, wherein the main dug is prepared from 41 raw materials such as radices trichosanthis, henbane, rhizoma drynariae and eucommia ulmoides, while the adjuvant is prepared from red flower, liquorice, centipede and shanxi overmature vinegar. The traditional Chinese medicine for external use has a remarkable effect on inhibiting gastric tumor, and is safe, effectively, quick, easy to operate, free of pain, and economic.
Description
Technical field
The present invention relates to a kind of external application Chinese medicine, specifically refer to a kind of external application Chinese medicine for the treatment of gastric cancer.
Background technology
Gastric cancer is stomach malignant tumor, and sickness rate ranks first in the various malignant tumor of China, and morbidity is obvious region difference, at the northwest of China and coastal region in east China sickness rate, apparently higher than southern area, sends out well the age more than 50 years old.Research finds, ediblely fire-cures for a long time, the high incidence of crowd's gastric cancer of salted food is carcinogenic with nitrite in food, mycotoxin, polycyclic aromatic hydrocarbon compounds etc. or procarcinogen content height is relevant; Secondly, the morbidity of gastric cancer is also relevant with helicobacter pylori infections, smoking, other pathological changes of stomach and gene etc.
At present, the Therapeutic Method for gastric cancer comprises the methods such as surgical operation, chemotherapy and radiotherapy.Adopt in recent years the method for Biotherapeutics, traditional Chinese medical herbal treatment gastric cancer also increasing.But in above-mentioned Therapeutic Method, the surgical treatments such as operation can cause compared with major injury health, Chinese and western drugs therapy also be take oral drugs as main, can cause damage to internal organs such as liver, kidneys equally.The present invention is under such technical background, and the theory based on traditional Chinese medical science inner disease outer treat proposes a kind of method of using external application Chinese medicine treatment gastric cancer, uses this medicine for external use treatment gastric cancer not need operation, is a kind of safe, effective, quick, easy to operate new therapy of economy again.
Summary of the invention
The object of the invention is to: the theory of Chinese medical science based on inner disease outer treat, proposes a kind of external application Chinese medicine for the treatment of gastric cancer.
The technical scheme that the present invention realizes above-mentioned purpose is:
A kind of external application Chinese medicine for the treatment of gastric cancer is provided, and it is prepared from by principal agent and accessory drugs, and described principal agent is prepared by the crude drug of following weight parts:
Described accessory drugs is made by following raw material medicaments: Flos Carthami 5～15, Radix Glycyrrhizae 5～15, Scolopendra 5～15 and Shanxi mature vinegar 450～500, wherein Flos Carthami, Radix Glycyrrhizae and Scolopendra all in unit of weight Shanxi mature vinegar in volume unit, and described unit of weight be " gram " time corresponding volume unit be " milliliter ".
In preferred embodiments of the present invention, described principal agent is prepared by the crude drug of following weight portion:
In preferred embodiments of the present invention, described accessory drugs is preferably prepared by following raw material: Flos Carthami 10, Radix Glycyrrhizae 10, Scolopendra 10 and Shanxi mature vinegar 485, wherein Flos Carthami, Radix Glycyrrhizae and Scolopendra all in unit of weight Shanxi mature vinegar in volume unit, and described unit of weight be " gram " time corresponding volume unit be " milliliter ".
Principal agent of the present invention is that described crude drug is pulverized in described ratio, mix homogeneously and obtaining.
The preparation method of accessory drugs of the present invention is that described Flos Carthami, Radix Glycyrrhizae, Scolopendra are pulverized as fine powder, is mixed in proportion and with slow fire, endures 30 minutes afterwards with described Shanxi mature vinegar, and to its volume half, concentration doubles, cooling after and get final product.
External application after described principal agent and accessory drugs allotment, the medication weight proportion of described principal agent and accessory drugs is 6-8:2-4, is preferably 7:3.
In pharmaceutical formulation of the present invention, " Sialon " of Bailey Myospalax Born is Tibetan language transliteration, formal name used at school Myospalax baileyi.Myospalax baileyi is lived in 2800 meters of height above sea level to 4300 Alpine Grasslands, all the year round in underground life, and dark 2 meters to 2.5 meters of cave, overhead approximately 30 centimetres of active tunnels, the rhizome specially pasturing, solitary life, copulation in April, 9 monthly output.The vital stage of Myospalax baileyi only had about 3 years.
Nineteen ninety, Bailey Myospalax Born is " the new medical material of a national class animal " by national official approval, and this is first " a class animal drug " that the medical authorities of China authority approval is since the establishment of the nation assert.
Bailey Myospalax Born nature and flavor " pungent salty, tepor is returned stomach, stomach warp ".Function cures mainly: have dispel the wind, the effect of cold expelling, dehumidifying, removing obstruction in the collateral to relieve pain, tonification stomach stomach, the diseases such as the limbs joint pain and swelling causing for anemofrigid-damp arthralgia, joint stuffiness, numbness of the skin, soreness of the waist and knees.Studies have shown that, Bailey Myospalax Born and Os Tigris have similar flavor efficacy.Its main chemical compositions and drug effect are extremely similar to Os Tigris.
Quality standard:
Adopted name: Bailey Myospalax Born
The Chinese phonetic alphabet: sai long gu
Standard No.: WS-207 (Z-46)-90
Character:
Skull is flat and wide, slightly triangular in shape; Nasal bone is longer, and end is blunted cone shape, two nasal bone leading edge comissures are recessed incise shallow; Cheekbone is interior to external expansion; Two top ridges are not joined forwardly mutually; Pillow back rigidity is strong, and pillow median ridge is undeveloped; Incisive foramen is little, the downward encirclement incisive foramen of premaxilla; Upper jaw bone has front tooth a pair of, without three pairs, canine tooth molar.After the normal tool one of third molar, stretch lobule, mandibular bone also has front tooth a pair of, large compared with upper front tooth, is cutter shape.
The Fructus Akebiae using in the present invention is the fruit of Akebia plants of Lardizabalaceae Caulis Akebiae; Property bitter, flat; Return liver, stomach warp; Effect: depressed liver-energy dispersing and QI regulating, eliminating stagnation.
The Herba Senecionis Argunensis using in external application Chinese medicine of the present invention is called large Herba Artemisiae Sieversianae, volume river Herba Senecionis Scandentis, is the herb of Compositae Senecio plant leatherleaf Herba Senecionis Scandentis, nature and flavor: micro-hardship, cold; Function cures mainly: heat-clearing and toxic substances removing, for venom, scorpion, bee sting wound, furuncle toxic swelling, eczema, dermatitis, acute conjunctivitis, pharyngitis.
The Gekko Swinhonis using in the present invention is that Gekkonidae animal is all without being dried of web Gekko Swinhonis, Gekko japonicus, webbed toe Gekko Swinhonis etc.; Nature and flavor: salty, cold; Mild toxicity; Return stomach warp; Function cures mainly: expelling wind for relieving convulsion, detoxicating and resolving stagnation of pathogens, for paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion.
In external application Chinese medicine side of the present invention, Scorpio, Radix Aconiti, Radix Aconiti Kusnezoffii mainly play the effect of killing cancerous cell; Hirudo, Bombyx Batryticatus, Moschus can promote drug osmotic to arrive focus to organization internal, and promote toxin to discharge, and draw out pus by applying a plaster to the affected part; Bailey Myospalax Born, Camphora, Flos Carthami all have eliminating evil effect, can removing obstruction in the collateral to relieve pain; By cooperatively interacting of all medicines, reach the effect of effective treatment gastric cancer.
By the great advantage of the method treatment gastric cancer of the external application of Chinese medicine, being need not be by operating on operation, and radiotherapy chemotherapy has thoroughly solved the various drawbacks of Chinese and western medicine traditional remedies, only by the external application of Chinese medicine, can cure, and treatment cost is low, and patient is without treatment misery.
The using method of external application Chinese medicine of the present invention: determine lesions position external application dispenser nearby according to doctor trained in Western medicine iconography means (nuclear-magnetism and CT), clinical people is 15-30g/ times/day by total amount, 4-5 days is 1 course for the treatment of, needs 6-7 the course for the treatment of can completed treatment altogether.1 routine patients with gastric cancer treatment whole process needs the total consumption 400-500 of accessory drugs milliliter, and the medication proportioning of described principal agent and described accessory drugs is 6-8:2-4, external application after principal agent and auxiliary medicine allotment.
The present invention is the medicine for external use that inventor passes through a kind of Chinese medicinal external application treatment gastric cancer of clinical experience research and development for many years.Its therapy apparatus built in: by infiltration function, arrive at focus, blocking-up cancerous cell existence, kills cancerous cell and dead cancer cell tissue liquid is excreted, and improves body's immunity simultaneously, finally reaches the object of curing gastric cancer.
External application Chinese medicine of the present invention can be with reference to the pharmacodynamics test of following animal model to the therapeutic effect of gastric cancer:
Select mice S
180solid tumor, 2 kinds of animal models for tumour of nude mice BGC-823 people transplantability gastric cancer, verify the antitumor action of external application Chinese medicine of the present invention.
Select 50 of SPF level ICR mices as S
180solid tumor laboratory animal; Select 50 of BALB/c male nude mouses as BGC-823 people's transplantability gastric cancer laboratory animal.
Two kinds of tumor model animals are all divided into 5 groups at random, 10 every group; The external application Chinese medicine that embodiment 1,2,3 is obtained, as 3 kinds of experimental drugs, adds starch as required to form the pasty state of conveniently smearing, and is respectively used to 3 experimental group A, B, C; The docetaxel injection of usining is used for positive controls as positive control drug; Remaining set, as blank group, gives the paste that Shanxi mature vinegar and starch allotment obtain;
The external application Chinese medicine of experimental group adopts and smears administration at tumor locus skin surface, smears dosage and is advisable with uniform fold tumor locus skin, successive administration 10 days; The docetaxel of positive controls adopts tail vein injection administration, and dosage is 20mg/kg/ time, and administration is 2 times weekly; The same experimental group of blank group administering mode and dosage.
Result shows:
1. mice S
180solid tumor animal model experiment: experimental group is respectively organized the continuous skin of external application Chinese medicine and smeared administration 10d, each experimental group gross tumor volume RTV compares significantly and reduces (P<0.01) with blank group, tumor proliferation rate T/C is respectively 21.10%, 22.00% and 25.89%, all be less than 40%, tumor weight tumour inhibiting rate is respectively 61.89%, 81.52% and 57.39%, all be greater than 30%, show that external application Chinese medicine of the present invention is to S
180the volume and weight growth of tumor has significant inhibitory action; The docetaxel injection of positive controls also can significantly suppress S
180the growth of tumor.Mouse Weight is respectively organized in experiment and appetite is showed no significantly abnormal.The docetaxel injection of positive controls is to S
180the body weight of transplanted tumor mice and appetite have all shown inhibitory action.
2. BGC-823 people's transplantability animal modal of gastric carcinoma experiment: the continuous skin of external application Chinese medicine of each experimental group is smeared administration 10d, respectively organizing of two batches of experiments significantly suppresses RTV after administration, be respectively: A:37.42%, B:35.13%, C:30.98%, T/C is all less than 40%, tumor weight tumour inhibiting rate is respectively A:53.80%, B:74.13%, C:73.89%, is all greater than 30%; Show that external application Chinese medicine of the present invention increases and all has remarkable inhibitory action BGC-823 people's transplantability gastric cancer volume and weight.The RTV of positive controls compares and also has significant reduction with blank group, and T/C is all less than 40%, and tumour inhibiting rate is greater than 30%, has shown the effect that significantly suppresses BGC-823 people's transplantability gastric cancer under same experimental condition.Mouse Weight is respectively organized in experiment and appetite is showed no significantly abnormal.The docetaxel injection of positive controls has all shown inhibitory action to body weight and the appetite of BGC-823 people's transplantability gastric cancer mice.
Above-mentioned description of test external application Chinese medicine of the present invention gastric cancer tool is had significant therapeutic effect.
The specific embodiment
Embodiment 1.
Treat an external application Chinese medicine for gastric cancer, by principal agent and the compound allotment of accessory drugs, formed, described principal agent is prepared by the crude drug of following weight (g):
Described accessory drugs is prepared by following raw material: Flos Carthami 10g, Radix Glycyrrhizae 10g, Scolopendra 10g and Shanxi mature vinegar 485ml.
Preparation method:
The crude drug of described principal agent is pulverized, and mix homogeneously obtains principal agent; Described Flos Carthami, Radix Glycyrrhizae, Scolopendra are pulverized as fine powder, endured 30 minutes with slow fire with after described Shanxi mature vinegar mixes, to its volume half, concentration doubles, and obtains accessory drugs after cooling; Gained principal agent and accessory drugs are made to paste medicine for external use after according to the weight ratio allotment evenly of 7:3.
Embodiment 2.
Treat an external application Chinese medicine for gastric cancer, by principal agent and the compound allotment of accessory drugs, formed, described principal agent is prepared by the crude drug of following weight (g):
Described accessory drugs is prepared by following raw material: Flos Carthami 15g, Radix Glycyrrhizae 15g, Scolopendra 5g and Shanxi mature vinegar 480ml.
Preparation method:
The crude drug of described principal agent is pulverized, and mix homogeneously obtains principal agent; Described Flos Carthami, Radix Glycyrrhizae, Scolopendra are pulverized as fine powder, endured 30 minutes with slow fire with after described Shanxi mature vinegar mixes, to its volume half, concentration doubles, and obtains accessory drugs after cooling; Gained principal agent and accessory drugs are made to paste medicine for external use after according to the weight ratio allotment evenly of 6:3.
Embodiment 3.
Treat an external application Chinese medicine for gastric cancer, by principal agent and the compound allotment of accessory drugs, formed, described principal agent is prepared by the crude drug of following weight (g):
Described accessory drugs is prepared by following raw material: Flos Carthami 12g, Radix Glycyrrhizae 15g, Scolopendra 12g and Shanxi mature vinegar 500ml.
Preparation method:
The crude drug of described principal agent is pulverized, and mix homogeneously obtains principal agent; Described Flos Carthami, Radix Glycyrrhizae, Scolopendra are pulverized as fine powder, endured 30 minutes with slow fire with after described Shanxi mature vinegar mixes, to its volume half, concentration doubles, and obtains accessory drugs after cooling; Gained principal agent and accessory drugs are made to paste medicine for external use after according to the weight ratio allotment evenly of 8:2.
Claims (6)
1. an external application Chinese medicine for the treatment of gastric cancer, is characterized in that, it is formed by principal agent and accessory drugs allotment, and described principal agent is prepared by the crude drug of following weight parts:
Described accessory drugs is made by following raw material medicaments: Flos Carthami 5～15, Radix Glycyrrhizae 5～15, Scolopendra 5～15 and Shanxi mature vinegar 450～500, wherein Flos Carthami, Radix Glycyrrhizae and Scolopendra all in unit of weight Shanxi mature vinegar in volume unit, and described unit of weight be " gram " time corresponding volume unit be " milliliter ".
2. external application Chinese medicine claimed in claim 1, is characterized in that, described principal agent is prepared by the crude drug of following weight portion:
。
3. external application Chinese medicine claimed in claim 1, it is characterized in that, described accessory drugs is prepared by following raw material: Flos Carthami 10, Radix Glycyrrhizae 10, Scolopendra 10 and Shanxi mature vinegar 485, wherein Flos Carthami, Radix Glycyrrhizae and Scolopendra all in unit of weight Shanxi mature vinegar in volume unit, and described unit of weight be " gram " time corresponding volume unit be " milliliter ".
4. external application Chinese medicine claimed in claim 1, is characterized in that: described principal agent and accessory drugs allotment weight ratio are 6-8:2-4.
5. external application Chinese medicine claimed in claim 1, is characterized in that: described principal agent and accessory drugs allotment weight ratio are 7:3.
6. the method for preparation external application Chinese medicine claimed in claim 1, comprises the following steps: the crude drug of described principal agent is pulverized in described ratio, and mix homogeneously obtains principal agent; The crude drug Flos Carthami of described accessory drugs, Radix Glycyrrhizae, Scolopendra are pulverized as fine powder, be mixed in proportion and with slow fire, endure 30 minutes afterwards with described Shanxi mature vinegar, to its volume half, concentration doubles, and obtains accessory drugs after cooling; Gained principal agent and accessory drugs are obtained to described external application Chinese medicine with the weight ratio mixing preparation of 6-8:2-4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410272848.XA CN104013757A (en) | 2014-06-18 | 2014-06-18 | Traditional Chinese medicine for external use for treating gastric cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410272848.XA CN104013757A (en) | 2014-06-18 | 2014-06-18 | Traditional Chinese medicine for external use for treating gastric cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104013757A true CN104013757A (en) | 2014-09-03 |
Family
ID=51430940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410272848.XA Pending CN104013757A (en) | 2014-06-18 | 2014-06-18 | Traditional Chinese medicine for external use for treating gastric cancer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104013757A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539455A (en) * | 2003-10-27 | 2004-10-27 | 李林龙 | Medical combination possessing effect for turning cancer off and rejuvenation |
| CN101167820A (en) * | 2006-11-21 | 2008-04-30 | 张财 | External-applied traditional Chinese medicine for curing uterus cancer and its preparation method |
-
2014
- 2014-06-18 CN CN201410272848.XA patent/CN104013757A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539455A (en) * | 2003-10-27 | 2004-10-27 | 李林龙 | Medical combination possessing effect for turning cancer off and rejuvenation |
| CN101167820A (en) * | 2006-11-21 | 2008-04-30 | 张财 | External-applied traditional Chinese medicine for curing uterus cancer and its preparation method |
Non-Patent Citations (3)
| Title |
|---|
| 刘沈林: "《难治性消化病辨治与验案》", 31 March 2011, 科学技术文献出版社 * |
| 曹雯等: ""中药治疗胃癌的用药规律"", 《中西医结合学报》 * |
| 范先基等: ""中医治疗胃癌研究进展"", 《中国医药指南》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101234188B (en) | Pharmaceutical composition for treating pain and preparation thereof | |
| CN107007714B (en) | A topical medicated liquor with effect in promoting callus formation | |
| CN101095933A (en) | Chinese traditional medicine compound recipe for healing bones and treating wound | |
| CN105878533A (en) | Chinese herbal medicine used for preventing and treating gosling plagues during anser cygnoides breeding | |
| CN102727693B (en) | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof | |
| CN105148230B (en) | Medicine for treating cancer pain and preparation method thereof | |
| CN104000946A (en) | Externally-applied traditional Chinese medicine for treating carcinoma of urinary bladder | |
| CN106265894A (en) | A kind of herbal medicine treating fowl bacterial diarrhoea and its production and use | |
| CN104013757A (en) | Traditional Chinese medicine for external use for treating gastric cancer | |
| CN104001121A (en) | External use traditional Chinese medicine for curing cerebral arteriosclerosis | |
| CN104721427A (en) | Traditional Chinese medicine preparation for treating rheumatic bone diseases | |
| CN1861119B (en) | Traditional Chinese medicine for treating rheumatosis and its preparation method | |
| CN104043043A (en) | Externally applied traditional Chinese medicine for treatment of lung cancer | |
| CN109125733A (en) | A kind of composition for the treatment of of arthritis and its application | |
| CN103861007A (en) | Chinese herbal medicine compound preparation for treating diarrhea of chicken | |
| CN104001122A (en) | External use traditional Chinese medicine for curing liver cancer | |
| CN102698204A (en) | Zhuang nationality transdermal patch for treating hyperplasia of mammary glands and preparation method of Zhuang nationality transdermal patch | |
| CN104000939A (en) | External use traditional Chinese medicine for curing bone cancer | |
| CN104001069A (en) | External use traditional Chinese medicine for curing kidney cancer | |
| CN103611032B (en) | The dyspeptic composition and method of making the same for the treatment of dog cat | |
| CN1064536C (en) | Full-divergence promoting medicine for curing fourth-phase carcinoma of stomach and its processing method | |
| CN106266500B (en) | A kind of Chinese medicine composition for treating the proliferation of mammary gland | |
| CN104491283A (en) | Traditional Chinese medicine powder for preventing and treating sow sterility | |
| CN1287829C (en) | Shenjin pill for treating hyperplastic osteoarthritis and rheumatism and its preparing method | |
| CN105106882A (en) | Traditional Chinese medicine composition for treating frostbite |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140903 |
|
| RJ01 | Rejection of invention patent application after publication |