CN104000945B - A kind of Chinese medicine for treating sports fatigue periostitis and preparation method thereof - Google Patents
A kind of Chinese medicine for treating sports fatigue periostitis and preparation method thereof Download PDFInfo
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- CN104000945B CN104000945B CN201410267031.3A CN201410267031A CN104000945B CN 104000945 B CN104000945 B CN 104000945B CN 201410267031 A CN201410267031 A CN 201410267031A CN 104000945 B CN104000945 B CN 104000945B
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Abstract
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine for treating sports fatigue periostitis and preparation method thereof.This is made up of the Chinese medicine material medicine of following parts by weight：50 70 parts of the root of herbaceous peony, 50 70 parts of Radix Glycyrrhizae, 15 25 parts of motherwort, 25 35 parts of Radix Angelicae Sinensis, 25 35 parts of ginseng, 25 35 parts of the Radix Astragali, 25 35 parts of the fruit of Chinese wolfberry, 15 25 parts of pseudo-ginseng, 15 25 parts of earthworm, 15 25 parts of stiff silkworm, 9 15 parts of frankincense, 9 15 parts of myrrh, 15 25 parts of catechu, 25 35 parts of the root of bidentate achyranthes, 15 25 parts of rheum officinale.Chinese medicine of the present invention has effects that replenishing and activating blood, disperse blood stasis and dredge collateral analgesic, is clinically used for treatment treatment fatigue periostitis, and cure rate is up to 63.75%, total effective rate 100%.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine for treating sports fatigue periostitis and its preparation
Method.
Background technology
Fatigue periostitis is a kind of more typical chronic Stress damage, under direct or indirect external force effect, by
A kind of limitation periosteal reaction for accumulating and gradually producing in local fatigue.Track and field, football, basketball, volleyballer are more common in,
Sundry item is not also rare, and it is primarily due to long-term a large amount of run and jumps training and competition, and fitness is poor, and it is improper to train
Or place is really up to the mark causes localised load excessive and fall ill, damage can form symptom and the signs such as local diffusivity vim and vigour stasis blocking.
When running jump motion, the thumb of shank（Toe）The shank musculus flexor such as muscle group, tibialis posterior shrinks repeatedly, causes accompanying place
Medial tibial periosteal is involved.If now loosen to release the tired sexual tension of Calf muscle not in time, or due to training burden
Increase suddenly, add the weakness on medial tibial periosteal this body structure, can all make medial tibial periosteal relaxation, damage, bleeding, become silted up and swell, generation
Shinbone endurance periostitis.Fatigue periostitis is with bone pain, mostly secret anguish, referred pain or shouting pain, and tenderness substantially, is pedaled and stretches outstanding
The pain increased when it is jump.Skin it is micro- it is red burn hot pain, between severe patient acute stage, locally has pitting edema, night to have
Involving property of having a rest pain, X-ray film has no bone degenerative change, and periostal surface protuberance has " concavo-convex particle " sense, main generation by it
In shin bone, but it is in the majority at 1/3 to be descended in medial leg, and degree, can be temporary transient when resting or reducing exercise using middle severe to be common
Alleviate, but once recover normal training and recur again, be not cured repeatedly, some sportsmen are as long as the sustainable several years.Severe shows as suffering from
There are red, swollen, hot, pain in various degree, periosteum protuberance, night interval involving property pain in portion, it is impossible to run and jumps training；Moderate is showed
For local edema, pain, but rear pain relief is opened in activity can still adhere to that training is jumped in the small race of intensity；The slight part that shows as has pain
Sense, substantially, activity can be adhered to running after opening jumps training to tenderness.
Fatigue periostitis not yet has the medicine for being exclusively used in fatigue periostitis to come out at present to move disease occurred frequently.
The content of the invention
The technical problems to be solved by the invention are to avoid the weak point present in above-mentioned prior art from having there is provided one kind
Chinese medicine of effect treatment treatment sports fatigue periostitis and preparation method thereof.
Another technical problem to be solved by this invention is to provide the preparation method of the Chinese medicine.
The present invention is achieved through the following technical solutions：
A kind of Chinese medicine for treating sports fatigue periostitis, is made up of the Chinese medicine material medicine of following parts by weight：
50-70 parts of the root of herbaceous peony, 50-70 parts of Radix Glycyrrhizae, 15-25 parts of motherwort, 25-35 parts of Radix Angelicae Sinensis, 25-35 parts of ginseng, Radix Astragali 25-
35 parts, 25-35 parts of the fruit of Chinese wolfberry, 15-25 parts of pseudo-ginseng, 15-25 parts of earthworm, 15-25 parts of stiff silkworm, 9-15 parts of frankincense, myrrh 9-
15 parts, 15-25 parts of catechu, 25-35 parts of the root of bidentate achyranthes, 15-25 parts of rheum officinale.
It is preferred that, the Chinese medicine of above-mentioned treatment fatigue periostitis is made up of the Chinese medicine material medicine of following parts by weight：
55-65 parts of the root of herbaceous peony, 55-65 parts of Radix Glycyrrhizae, 18-22 parts of motherwort, 28-32 parts of Radix Angelicae Sinensis, 28-32 parts of ginseng, Radix Astragali 28-
32 parts, 28-32 parts of the fruit of Chinese wolfberry, 18-22 parts of pseudo-ginseng, 18-22 parts of earthworm, 18-22 parts of stiff silkworm, 10-14 parts of frankincense, myrrh
10-14 parts, 18-22 parts of catechu, 28-32 parts of the root of bidentate achyranthes, 18-22 parts of rheum officinale.
It is furthermore preferred that the Chinese medicine of above-mentioned treatment fatigue periostitis, is made up of the Chinese medicine material medicine of following parts by weight：
60 parts of the root of herbaceous peony, 60 parts of Radix Glycyrrhizae, 20 parts of motherwort, 30 parts of Radix Angelicae Sinensis, 30 parts of ginseng, 30 parts of the Radix Astragali, 30 parts of the fruit of Chinese wolfberry, three
7 20 parts, 20 parts of earthworm, 20 parts of stiff silkworm, 12 parts of frankincense, 12 parts of myrrh, 20 parts of catechu, 30 parts of the root of bidentate achyranthes, 20 parts of rheum officinale.
The ratio of above weight proportion is obtained by science screening, for especial patient, such as severe or mild, fat
Or the patient of slight of stature, the proportioning of the amount of composition can be accordingly adjusted, is increased or decreased no more than 100%, drug effect is basically unchanged.
The Chinese medicine of above-mentioned treatment fatigue periostitis, the dosage form of the Chinese medicine is oral formulations.Preferably pill.
The preparation method of the Chinese medicine of above-mentioned treatment fatigue periostitis, is comprised the following steps：
（a）Pseudo-ginseng, that catechu is ground into fine powder is standby；
（b）By the root of herbaceous peony, Radix Glycyrrhizae, motherwort, Radix Angelicae Sinensis, ginseng, the Radix Astragali, the fruit of Chinese wolfberry, earthworm, stiff silkworm, frankincense, myrrh,
The root of bidentate achyranthes, the taste material of rheum officinale 13, which are added, to be stated the decoctings of 8~12 times of weight of medicinal material and boils 2 times, is decocted 1~2 hour every time, merges decocting twice
Go out liquid, filter, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.25~1.28；
（c）By step（a）The fine medicinal material powder and step of gained（b）The clear cream of gained is mixed, and adds honey and small honey pill is made,
Every 10 ball weight 1g.
Chinese medicine of the present invention has effects that replenishing and activating blood, disperse blood stasis and dredge collateral analgesic, is clinically used for treatment treatment fatigability periosteum
It is scorching.
The present inventor summarizes by substantial amounts of clinical practice to be thought：Fatigue periostitis etiology and pathogenesis is mainly usually passages through which vital energy circulates
Lose and supported in honor, motion is improper to cause muscle contraction, and damage can form local diffusivity vim and vigour stasis blocking and cause.In the present invention reuse the root of herbaceous peony,
Radix Glycyrrhizae regulating the function of the liver and spleen, relieving spasm to stop pain is monarch；Motherwort, Radix Angelicae Sinensis, pseudo-ginseng, earthworm, catechu, frankincense, myrrh are promoting blood circulation and removing blood stasis, easypro
Through dredging collateral, improve microcirculation analgesic；Ginseng, Radix Astragali tonifying Qi, to strengthen effect of promoting blood circulation and stopping pain, are altogether ministerial drug；The root of bidentate achyranthes, the fruit of Chinese wolfberry
Tonify the liver and kidney so that medicine such as liver kidney enhancing muscles and bones function, rheum officinale is let out clearly because hot in stagnation of blood in the tendons, is adjuvant.It is all
Medicine is shared, and replenishing and activating blood, the work(of disperse blood stasis and dredge collateral analgesic are played altogether so that generally, hemostasis is eliminated tendon and vessel, medial tibial periosteal microcirculation
Improve, so as to fundamentally cure fatigue periostitis.
The advantage of the invention is that：
（1）The invention provides a kind of Chinese medicine of new treatment sports fatigue periostitis, clinical needs are met.
（2）The present invention will treat and pill is prepared into after the traditional Chinese medicine extraction of sports fatigue periostitis, volume-diminished, transport,
Carry, it is convenient to take.
（3）Clinical test results are shown, after 80 fatigue periostitis treat 2 courses for the treatment of through patient, are fully recovered 51, effective
26, take a turn for the better 3, invalid 0, cure rate is up to 63.75%, total effective rate 100%.
Embodiment
The present invention is further described with reference to specific embodiment, so that those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
Prescription：Root of herbaceous peony 600g, Radix Glycyrrhizae 600g, motherwort 200g, Radix Angelicae Sinensis 300g, ginseng 300g, Radix Astragali 300g, the fruit of Chinese wolfberry
300g, pseudo-ginseng 200g, earthworm 200g, stiff silkworm 200g, frankincense 120g, myrrh 120g, catechu 200g, root of bidentate achyranthes 300g, rheum officinale
200g。
Preparation method：
（a）Pseudo-ginseng, that catechu is ground into fine powder is standby；
（b）By the root of herbaceous peony, Radix Glycyrrhizae, motherwort, Radix Angelicae Sinensis, ginseng, the Radix Astragali, the fruit of Chinese wolfberry, earthworm, stiff silkworm, frankincense, myrrh,
The root of bidentate achyranthes, the taste material of rheum officinale 13, which are added, to be stated the decoctings of 10 times of weight of medicinal material and boils 2 times, is decocted 1.5 hours every time, merges twice fried
Liquid, filtration, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.25~1.28；
（c）By step（a）The fine medicinal material powder and step of gained（b）The clear cream of gained is mixed, and adds honey and small honey pill is made,
Every 10 ball weight 1g.
1000g is prepared altogether.Usage and dosage：Orally, each 6-12g, 2-3 times on the one.
Embodiment 2
Prescription：Root of herbaceous peony 650g, Radix Glycyrrhizae 550g, motherwort 220g, Radix Angelicae Sinensis 280g, ginseng 320g, Radix Astragali 280g, the fruit of Chinese wolfberry
320g, pseudo-ginseng 180g, earthworm 220g, stiff silkworm 180g, frankincense 140g, myrrh 100g, catechu 220g, root of bidentate achyranthes 280g, rheum officinale
220g。
Preparation method：
（a）Pseudo-ginseng, that catechu is ground into fine powder is standby；
（b）By the root of herbaceous peony, Radix Glycyrrhizae, motherwort, Radix Angelicae Sinensis, ginseng, the Radix Astragali, the fruit of Chinese wolfberry, earthworm, stiff silkworm, frankincense, myrrh,
The root of bidentate achyranthes, the taste material of rheum officinale 13 are boiled 2 times plus the decocting for stating 8 times of weight of medicinal material, are decocted 1 hour every time, merge fried liquid twice, filter
Cross, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.25~1.28；
（c）By step（a）The fine medicinal material powder and step of gained（b）The clear cream of gained is mixed, and adds honey and small honey pill is made,
Every 10 ball weight 1g.
1000g is prepared altogether.Usage and dosage：Orally, each 6-12g, 2-3 times on the one.
Embodiment 3
Prescription：Root of herbaceous peony 550g, Radix Glycyrrhizae 650g, motherwort 180g, Radix Angelicae Sinensis 320g, ginseng 280g, Radix Astragali 320g, the fruit of Chinese wolfberry
280g, pseudo-ginseng 220g, earthworm 180g, stiff silkworm 220g, frankincense 100g, myrrh 140g, catechu 180g, root of bidentate achyranthes 320g, rheum officinale
180g。
Preparation method：
（a）Pseudo-ginseng, that catechu is ground into fine powder is standby；
（b）By the root of herbaceous peony, Radix Glycyrrhizae, motherwort, Radix Angelicae Sinensis, ginseng, the Radix Astragali, the fruit of Chinese wolfberry, earthworm, stiff silkworm, frankincense, myrrh,
The root of bidentate achyranthes, the taste material of rheum officinale 13 are boiled 2 times plus the decocting for stating 12 times of weight of medicinal material, are decocted 2 hours every time, merge fried liquid twice,
Filtration, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.25~1.28；
（c）By step（a）The fine medicinal material powder and step of gained（b）The clear cream of gained is mixed, and adds honey and small honey pill is made,
Every 10 ball weight 1g.
1000g is prepared altogether.Usage and dosage：Orally, each 6-12g, 2-3 times on the one.
Embodiment 4
Prescription：Root of herbaceous peony 700g, Radix Glycyrrhizae 500g, motherwort 250g, Radix Angelicae Sinensis 250g, ginseng 50g, Radix Astragali 250g, the fruit of Chinese wolfberry
350g, pseudo-ginseng 150g, earthworm 250g, stiff silkworm 150g, frankincense 150g, myrrh 90g, catechu 250g, root of bidentate achyranthes 250g, rheum officinale
250g。
Preparation method be the same as Example 1.1000g is prepared altogether.Usage and dosage：Orally, each 6-12g, 2-3 times on the one.
Embodiment 5
Prescription：Root of herbaceous peony 500g, Radix Glycyrrhizae 700g, motherwort 150g, Radix Angelicae Sinensis 350g, ginseng 250g, Radix Astragali 350g, the fruit of Chinese wolfberry
250g, pseudo-ginseng 250g, earthworm 150g, stiff silkworm 250g, frankincense 90g, myrrh 150g, catechu 150g, root of bidentate achyranthes 350g, rheum officinale
150g。
Preparation method be the same as Example 1.1000g is prepared altogether.Usage and dosage：Orally, each 6-12g, 2-3 times on the one.
Clinical pharrnacokinetics experiment has been carried out to embodiments of the invention l preparation, it is as a result as follows：
1 data and method
1st, physical data treats 80, man 58, female 22 altogether；It is 10~28 years old age, average 19.7 years old；The course of disease 2 months
~5 years, average 1.9 years, shin, periosteitis of fibula were with patient 60, periosteitis of tibia 18, periosteitis of fibula 2.
2nd, treatment method
Give the Chinese medicine of the treatment hyperthyroid patient bone density reduction of the present invention, each 10g, 3 times a day.It is within 7 days 1 course for the treatment of.
2 courses for the treatment of are treated altogether.
3rd, criterion of therapeutical effect is fully recovered：Pain, tenderness, swelling are wholly absent, and functional rehabilitation is normal.It is effective：It is pain, tenderness, swollen
Swollen obvious disappearance, function is accessible.Take a turn for the better：Pain, tenderness, swelling have mitigated, and dysfunction makes moderate progress.It is invalid：Pain,
Tenderness, swelling are without improvement, and dysfunction is without improvement.
4th, after 80 fatigue periostitis of therapeutic effect treat 2 courses for the treatment of through patient, fully recover 51, effective 26, take a turn for the better
3, invalid 0, cure rate is up to 63.75%, total effective rate 100%.
Claims (6)
1. a kind of Chinese medicine for treating sports fatigue periostitis, is made up of the Chinese medicine material medicine of following parts by weight：
50-70 parts of the root of herbaceous peony, 50-70 parts of Radix Glycyrrhizae, 15-25 parts of motherwort, 25-35 parts of Radix Angelicae Sinensis, 25-35 parts of ginseng, Radix Astragali 25-35
Part, 25-35 parts of the fruit of Chinese wolfberry, 15-25 parts of pseudo-ginseng, 15-25 parts of earthworm, 15-25 parts of stiff silkworm, 9-15 parts of frankincense, myrrh 9-15
Part, 15-25 parts of catechu, 25-35 parts of the root of bidentate achyranthes, 15-25 parts of rheum officinale.
2. the Chinese medicine for the treatment of sports fatigue periostitis according to claim 1, it is characterised in that by following parts by weight
Chinese medicine material medicine is made：
55-65 parts of the root of herbaceous peony, 55-65 parts of Radix Glycyrrhizae, 18-22 parts of motherwort, 28-32 parts of Radix Angelicae Sinensis, 28-32 parts of ginseng, Radix Astragali 28-32
Part, 28-32 parts of the fruit of Chinese wolfberry, 18-22 parts of pseudo-ginseng, 18-22 parts of earthworm, 18-22 parts of stiff silkworm, 10-14 parts of frankincense, myrrh 10-
14 parts, 18-22 parts of catechu, 28-32 parts of the root of bidentate achyranthes, 18-22 parts of rheum officinale.
3. the Chinese medicine for the treatment of sports fatigue periostitis according to claim 2, it is characterised in that by following parts by weight
Chinese medicine material medicine is made：
60 parts of the root of herbaceous peony, 60 parts of Radix Glycyrrhizae, 20 parts of motherwort, 30 parts of Radix Angelicae Sinensis, 30 parts of ginseng, 30 parts of the Radix Astragali, 30 parts of the fruit of Chinese wolfberry, pseudo-ginseng 20
Part, 20 parts of earthworm, 20 parts of stiff silkworm, 12 parts of frankincense, 12 parts of myrrh, 20 parts of catechu, 30 parts of the root of bidentate achyranthes, 20 parts of rheum officinale.
4. the Chinese medicine of the treatment sports fatigue periostitis according to claim 1 or 2 or 3, it is characterised in that the Chinese medicine
Dosage form is oral formulations.
5. the Chinese medicine for the treatment of sports fatigue periostitis according to claim 4, it is characterised in that the form of the Chinese medicine
Formula is pill.
6. the preparation method of the Chinese medicine of the treatment sports fatigue periostitis according to claim 1 or 2 or 3, comprising as follows
Step：
（a）Pseudo-ginseng, that catechu is ground into fine powder is standby；
（b）By the root of herbaceous peony, Radix Glycyrrhizae, motherwort, Radix Angelicae Sinensis, ginseng, the Radix Astragali, the fruit of Chinese wolfberry, earthworm, stiff silkworm, frankincense, myrrh, the root of bidentate achyranthes,
The taste medicinal material of rheum officinale 13, which is added, to be stated the decoctings of 8~12 times of weight of medicinal material and boils 2 times, is decocted 1~2 hour every time, merges twice fried
Liquid, filtration, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.25~1.28；
（c）By step（a）The fine medicinal material powder and step of gained（b）The clear cream of gained is mixed, and adds honey and small honey pill, every 10 is made
Ball weight 1g.
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| CN104645021A (en) * | 2015-03-12 | 2015-05-27 | 肖冻 | Traditional Chinese medicine preparation with effect of eliminating exercise induced physical fatigue |
| CN104644876A (en) * | 2015-03-12 | 2015-05-27 | 肖冻 | Traditional Chinese medicine preparation for treating periostitis caused by sports fatigue |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103656510A (en) * | 2013-12-11 | 2014-03-26 | 张晨 | Traditional Chinese medicine decoction for treating periostitis |
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| CN103656510A (en) * | 2013-12-11 | 2014-03-26 | 张晨 | Traditional Chinese medicine decoction for treating periostitis |
Non-Patent Citations (3)
| Title |
|---|
| 应用经方治疗痹症的心得体会;温桂荣;《中华中医药杂志》;20140201;第29卷(第2期);第467-470页 * |
| 空勤学员运动性胫腓骨骨膜炎的预防及处理;段宗礼等;《中国疗养医学》;20090830;第18卷(第08期);第705页 * |
| 芍药甘草汤临床应用举隅;钟宝源等;《河北中医》;19860630(第03期);第30页 * |
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