CN104000917B

CN104000917B - A kind of Chinese medicine preparation treating eczema

Info

Publication number: CN104000917B
Application number: CN201410250329.3A
Authority: CN
Inventors: 徐艳; 苏家茹; 任红; 李翠美
Original assignee: Qingdao Municipal Hospital
Current assignee: Qingdao Municipal Hospital
Priority date: 2014-06-06
Filing date: 2014-06-06
Publication date: 2016-08-24
Anticipated expiration: 2034-06-06
Also published as: CN104000917A

Abstract

The invention discloses a kind of Chinese medicine preparation treating eczema, Chinese medicine material by following parts by weight is formulated: kuh-seng 23 parts, 58 parts of Radix Glycyrrhizae, golden cypress 24 parts, alumen 35 parts and the root of large-flowered skullcap 24 parts, pass through the external application of Chinese medicine, clearing heat and detoxicating, dampness removing of subsiding a swelling, dispel eczema and skin rotten to the corn, exudative that eczema causes damages, take effect rapidly, result for the treatment of good.

Description

A kind of Chinese medicine preparation treating eczema

Technical field

The invention belongs to field of traditional Chinese medicine technology, particularly to a kind of Chinese medicine preparation treating eczema.

Background technology

Medically, skin disease is the disease about skin, be have a strong impact on people's health common disease, One of frequently-occurring disease, such as leprosy, scabies, nosomycosis, bacterial skin infections etc..Skin disease is skin (bag Include hair and first) affected by internal and external factor after, its form, 26S Proteasome Structure and Function all change, produce Raw pathologic process, and produce various clinical successively performance accordingly.The dermopathic incidence of disease is the highest, compares more Relatively light, the most unhealthful, but minority is heavier even can be with threat to life.

Eczema is a kind of scytitis reaction of the acute pruritus caused by multiple internal and external factor.Point acute, Three phases subacute, chronic.Acute stage tool oozes out tendency, and chronic phase then infiltrates, plump.Some patient is straight Connect and show as chronic eczema.Skin damages features such as having polymorphy, symmetry, itch and easy recurrent exerbation.

Eczematosis, because of complexity, is often internal and external reasons interaction result.Internal cause such as chronic digestive system disease, Stress, insomnia, fatigue, emotional change, endocrinopathy, infection, dysbolism Deng, external cause such as living environment, climate change, food etc. all can affect the generation of eczema.Environmental stimuli is such as Daylight, cold, be dried, hot, hot water is scalded and various animal skin, plant, cosmetics, fertilizer Soap, staple fibre etc. all can induce.It it is a kind of delayed allergy that causes of the complicated inside and outside factor.

Skin damage is just papule, papulo-vesicle or the phlysis of most intensive grain grain size, substrate flush, by Gradually merging in flakes, owing to scratching, papule, papulo-vesicle or blister top are oozed out in obvious point-like after scratching And little rotten to the corn face, blur margin.Such as scabies secondary infection, inflammation becomes apparent from, and can form warts, purulence scab, hair Capsulitis, furuncle etc., conscious violent itch.

Summary of the invention

The present invention provides a kind of Chinese medicine preparation treating eczema, by the external application of Chinese medicine, and clearing heat and detoxicating, detumescence Dampness removing, dispel eczema and skin rotten to the corn, exudative that eczema causes damages, take effect rapidly, result for the treatment of good.

The Chinese medicine preparation of the treatment treatment eczema of the present invention, it is characterised in that by the Chinese medicine of following parts by weight Raw material is formulated: kuh-seng 2-3 part, Radix Glycyrrhizae 5-8 part, golden cypress 2-4 part, alumen 3-5 part and the root of large-flowered skullcap 2-4 part.

As preferably, prepare by following parts by weight: kuh-seng 2 parts, 6 parts of Radix Glycyrrhizae, golden cypress 3 parts, withered Alum 4 parts and the root of large-flowered skullcap 3 parts.

Preparation method is to weigh raw material by above-mentioned parts by weight, pulverizes, and crosses 800-1000 mesh sieve, makes The medicinal powder boiling water sieved is melted by the used time, and after naturally cooling down, soak is in affected part, twice on the one, once 15-30 minute, 7 days be a course for the treatment of.

Pharmacology analysis:

Kuh-seng: bitter, cold in nature；Matrine can reduce the release of Anaphylactic mediator, for immunodepressant, its The concentration of suppression 50%T cell proliferation is 0.55-0.56m part/ml；The concentration of suppression IL-2 yield is 0.1m Part/k part.Having heat-clearing and damp-drying drug, effect of desinsection, kuh-seng bath can remove damp-heat in lower-JIAO, and desinsection is only Itch, pruitus had good mitigation, vegetable Chinese herbal medicine can Bergamot Mint Extract, dredging also Convergence pore, removes skin endotoxin contamination, abundant herbal nutrition, promotes damaged blood vessels nerve cell Growth and reparation, recover subcutaneous capillary cell viability, skin reappears and compacts fine and smooth, plays beauty treatment The effect of skin care.

Radix Glycyrrhizae: invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription, for spleen Stomach is weak, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction urgency pain, carbuncle sore tumefacting virus, Cushion toxicity, strong；Radix Glycyrrhizae also has anti-inflammatory, anti-allergic effects, and the throat that can protect inflammation is gentle Pipe mucous membrane.Extract of licorice root and glycyrrhizic acid have the detoxication of similar glucuronic acid to some poisonous substance.

Golden cypress: bitter, cold in nature.Return kidney, bladder, large intestine channel；Heat-clearing, eliminating dampness, purging intense heat, removing toxic substances. Control hot dysentery, have loose bowels, quench one's thirst, jaundice, impotence, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, also under leukorrhea, Hectic fever due to yin labor heat, red eye, swell pain, aphthae, sore swollen toxin.Golden cypress can be resisted caused by many factors Inflammatory reaction.Golden cypress has obvious antiinflammatory action to the skin of infection of staphylococcus aureus.Golden cypress is permissible Effectively resisting the mouse ear profile swelling caused by croton oil, that can effectively suppress caused by acetic acid is little The inflammatory effects that mouse abdominal cavity capillary permeability strengthens.Use mouse hot way throe Germicidal efficacy tetrandra root The analgesic activity of golden cypress gel.Result shows, golden cypress can effectively reduce the penetrating of mouse capillary Property, the inflammatory reaction of many of croton oil of suppression, alleviate the arthritis of mouse, by mouse macrophage The observation of function finds that golden cypress can improve the cytophagous function of mouse, effectively suppresses inflammatory effect.Cause This golden cypress can be used for treatment of arthritis.

Alumen: puckery, cool, slightly poisonous；External application can be detoxified desinsection, and eliminating dampness is antipruritic；Interior hemostasis, antidiarrheal, Reduce phlegm.Cure mainly: apoplexy；Epilepsy；Larynx numbness；The wet sore of mange；Swollen ulcer drug；Scald；Dispute is raw Sore；Belepharitis ciliaris eye；Discharging ear；Polyp in nose；Sore hemorrhoid pain；Uterine bleeding；Bleeding from five sense organs or subcutaneous tissue；Bleeding due to trauma； Rush down nine dysentery for a long time；The lower pruritus vulvae of band；Prolapse of the anus；Metroptosis etc..Nature and flavor are sour and astringent, cold, poisonous.Therefore have antibacterial Effect, astriction etc., can be used as Chinese medicine.

The root of large-flowered skullcap: Gui Jing: bitter, cold in nature, return lung, courage, spleen, stomach, large intestine, small intestinl channel；Can heat-clearing Eliminating dampness, purging intense heat and detonicating, hemostasis, the effect such as antiabortive；For damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, Rushing down dysentery, jaundice, cough with lung heat, high hot polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.Have: 1, antibacterial action: to shigella dysenteriae, typhoid bacillus, paratyphosum Bacterium, comma bacillus, Escherichia coli, Proteus, Pseudomonas aeruginosa, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus (a, B), Diplococcus pneumopniae, white Larynx bacillus etc. has inhibitory action；2, antifungic action: suppression dog denticle born of the same parents bacterium and trichophyton, is permitted Lan Shi achorion, the mutation of Lan Shi achorion Mongolia, homocentricity trichophyta and rust trichophyta, violet hair Tinea bacterium, Trichophyton concentricum, oidium schoenleinii, Microsporon audouini, wool sample microspore Tinea bacterium, epidermophyton rubrum, K, W, family name Epidermophyton, star nocardia etc.；3, antiviral work With: hepatitis B virus DNA is replicated with inhibitory action；4, anti-inflammatory antiallergic action: to adjuvanticity Arthritis has inhibitory action, and passive cutaneous anaphylaxis (PCA) is had inhibitory action.

The Chinese medicine preparation of the present invention, is externally applied to affected part, uses in kuh-seng, golden cypress, alumen and the root of large-flowered skullcap four taste Medicine, clearing heat and detoxicating, detumescence dampness removing, remove the toxin in skin, impurity, promote that damaged blood vessels is neural thin The growth of born of the same parents and reparation, treat eczema, eliminate erosion, skin damage symptom that eczema causes, compatibility Radix Glycyrrhizae Anti-inflammatory, antiallergy and detoxicating functions, alleviate the toxicity of alumen, and external application uses, and has no side effect.

Outcome measure: eczema Symptoms is the most intensive papule of grain grain size, papulo-vesicle or little water Blister, substrate flush, gradually merges in flakes, owing to scratching, after papule, papulo-vesicle or blister top are scratched Oozing out in obvious point-like and little rotten to the corn face, blur margin, such as scabies secondary infection, inflammation becomes apparent from, can shape Become warts, purulence scab, folliculitis, furuncle etc., conscious violent itch.

Recovery from illness: symptom is wholly absent, skin damages or rotten to the corn without papule, skin.

Take a turn for the better: symptom disappears substantially.

Invalid: all diseases are without improving.

Treatment results: treatment eczema 147 example, weighs raw material by the parts by weight of the formula of the present invention, grinds Grinds, crosses 800-1000 mesh sieve, is melted by the medicinal powder boiling water sieved during use, naturally wet after cooling Spreading on affected part, twice on the one, one time 15-30 minute, 7 days be a course for the treatment of, and 134 examples of fully recovering are good Turn 6 examples, invalid 7 examples, cure rate 95%, inefficiency 5%.

Attached a few example case is described further:

Case 1: Wang, man, 34 years old, hand papule, substrate flush, Symptoms last 15 days, by In scratching, become obvious point-like to ooze out and rotten to the corn face, be diagnosed as acute eczema, external application medicine of the present invention 3 It takes effect, the healing of rotten to the corn face, and base flush fades away, and fully recovers after 7 days, follows up a case by regular visits to 2 months without recurrence.

Case 1: Zhang, female, 37 years old, the back of the hand and ten referred to that eczema illing skin thickens, infiltrates, palm fibre Redness, rough surface, cover the scales of skin that peel off, or form a scab because scratching, conscious acute pruritus, the course of disease is indefinite, easily Recurrence, prolonged does not heals, and is diagnosed as chronic eczema, and external application medicine of the present invention takes effect for 7 days, itch alleviates, The scales of skin that peel off gradually comes off, and after 21 days, the scales of skin that peel off comes off, skin smooth, follows up a case by regular visits to 1 year without recurrence.

Detailed description of the invention

Embodiment 1

Kuh-seng 2 parts, 6 parts of Radix Glycyrrhizae, golden cypress 3 parts, alumen 4 parts and the root of large-flowered skullcap 3 parts.

Claims

1. the Chinese medicine coating agent treating eczema, it is characterised in that the Chinese medicine by following parts by weight is former Expect formulated: kuh-seng 2-3 part, Radix Glycyrrhizae 5-8 part, golden cypress 2-4 part, alumen 3-5 part and root of large-flowered skullcap 2-4 Part.

The Chinese medicine coating agent for the treatment of eczema the most according to claim 1, it is characterised in that by following The Chinese medicine material of parts by weight is formulated: kuh-seng 2 parts, 6 parts of Radix Glycyrrhizae, golden cypress 3 parts, alumen 4 Part and the root of large-flowered skullcap 3 parts.