CN104000847A - Method for improving solubility and clarity of Maoxijiao - Google Patents
Method for improving solubility and clarity of Maoxijiao Download PDFInfo
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- CN104000847A CN104000847A CN201410246381.1A CN201410246381A CN104000847A CN 104000847 A CN104000847 A CN 104000847A CN 201410246381 A CN201410246381 A CN 201410246381A CN 104000847 A CN104000847 A CN 104000847A
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Abstract
The invention relates to a method for improving the solubility and clarity of Maoxijiao. The method comprises the following steps: (1) alkalizing and soaking the yak skin, thus obtaining the yak skin soaked in alkali; (2) carrying out primary mechanical unhairing on the yak skin soaked in alkali; (3) soaking the yak skin after primary unhairing, thus obtaining the dealkalized yak skin; (4) carrying out secondary mechanical unhairing on the dealkalized yak skin; (5) soaking the yak skin after secondary unhairing, thus obtaining the dealkalized and unhaired yak skin; (6) adding protease to degrease the dealkalized and unhaired yak skin; (7) blanching the degreased yak skin; (8) extracting the blanched yak skin with water, thus obtaining filtrate A; (9) concentrating the filtrate A, then adding an alum solution, and standing and refrigerating to obtain filtrate B; (10) concentrating the filtrate B, and then extracting the foam, thus obtaining glue juice; (11) preparing a rock sugar solution; (12) adding the rock sugar solution to the glue juice, and then drying the solution, thus obtaining Maoxijiao powder; (13) mixing prepared rehmannia root, radix astragali, angelica sinensis, Chinese dates, medlar and dried longan pulp, then extracting the mixture with water, and concentrating and drying the mixture, thus obtaining accessory powder; (14) mixing the Maoxijiao powder with the accessory powder uniformly, and granulating the mixture, thus obtaining Maoxijiao. The method is simple in process and low in cost.
Description
Technical field
The present invention relates to Chinese medicine composition preparing technical field, relate in particular to a kind of method of improving Yak skin glue dissolubility, clarity.
Background technology
Yak skin glue be take yak skin as primary raw material, is aided with Qinghai-Tibet special medicinal material---and Radix Rehmanniae Preparata, the Radix Astragali, Radix Angelicae Sinensis, Fructus Jujubae, Fructus Lycii, Arillus Longan, can be made into the granule with blood tonification effect through extracting.Its production process is generally: pretreated yak skin dry product is put in multi-function extractor, first added the water of 1 ~ 2 times of weight, then add weight 1/300 ~ 1/1000NaOH defat, airtight extraction pot, heats, and boils 0.5 ~ 1 hour, pressure 0.11 ~ 0.12MPa, repeatedly adds water and rinses to pH value to neutral, puts water purification, add again 1 ~ 2 times, water, heating, pressure 0.1 ~ 0.15MPa, extract, time is 8 ~ 20 hours, and extract filters, filtrate for later use; Filtering residue adds 1 ~ 2 times of water of weight, second extraction, and 1 ~ 8 hour time, extract filters, merging filtrate, in extraction, once, 5 minutes time, 60 ℃ of concentrated medicaments are to density 1.074 ~ 1.091g/cm in aerofluxus per hour
3, after spraying is dry, obtain rubber powder.
But there is bad, the muddy problem of dissolubility in the Yak skin glue granule that adopts this explained hereafter.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of technique method of improving Yak skin glue dissolubility, clarity simple, with low cost.
For addressing the above problem, a kind of method of improving Yak skin glue dissolubility, clarity of the present invention, comprises the following steps:
(1) yak skin 3000 ~ 5000g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 24 ~ 48 hours, then by 2 ~ 3 times of its weight, adding mass concentration is 0.5 ~ 10% alkali, in temperature, be to soak 24 ~ 72 hours under the condition of 20 ~ 38 ℃, obtain the yak skin after caustic dip;
(2) the yak skin after described caustic dip is put into electronic rotary drum, every 2 ~ 4 hours rotary drums, rotate 5 ~ 20 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers;
(3) the yak skin after described once depilation is added to water soaking by 3 ~ 5 times of its weight, after 2 ~ 4 hours, obtain the yak skin after dealkalize;
(4) the yak skin after described dealkalize is cut into the bulk of 50 ~ 70cm, then by 2 ~ 3 times of its weight, adding mass concentration is 0.5 ~ 10% alkali, soak 24 ~ 72 hours under temperature is the condition of 20 ~ 38 ℃ after, insert in described electronic rotary drum, every 2 ~ 4 hours rotary drums, rotate 5 ~ 20 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation;
(5) by the yak skin after the depilation of described secondary, in water temperature, be to soak dealkalize under the condition of 20 ~ 30 ℃, repeat 1 ~ 4 time, each 10 ~ 30 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers;
(6) in the yak skin of described dealkalize depilation, adding the protease of its weight 0.2 ~ 0.8%, is defat 3 ~ 15 minutes under the condition of 30 ~ 60 ℃ in temperature, obtains the yak skin after defat;
(7) by scald skin 1 ~ 3 time of the water of 5 ~ 20 times of its quality for the yak skin after described defat, wherein scald in 50 ~ 80 ℃ of hot water of the 1st temperature skin 3 ~ 10 minutes, dewatering is placed half an hour, again change water, scald in 40 ~ 60 ℃ of water of the 2nd temperature skin 5 ~ 10 minutes, again change water, the skin 3 ~ 10 minutes of scalding in 50 ~ 80 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin;
(8) described yak skin of scalding after skin is extracted with the water of 8 ~ 12 times of its quality, after 2 ~ 10 hours, filter, discard residue, obtain filtrate A;
(9) after described filtrate A being concentrated into proportion and being 1:1.1 ~ 1:1.3, adding mass concentration is 2 ~ 10% alum solution, stirs, and standing 4 ~ 12h at 25 ~ 35 ℃, then, at 5 ~ 10 ℃ of cold preservation 6 ~ 12h, removes by filter precipitate, obtains liquor B;
By described liquor B when 60 ~ 80 ℃ are concentrated into proportion and are 1:1.3 ~ 1:1.5, add 0 ~ 10 ℃ of pure water to start to carry foam, repeatable operation 3 ~ 8 times, obtains water content and is 50 ~ 70% shinny glue juice;
(11) crystal sugar is filtered after the water dissolution by 3 ~ 8 times of its quality, obtain crystal sugar solution;
(12) in described glue juice, add the described crystal sugar solution of its volume 0.2 ~ 0.5%, stir, obtain glue, the spray-dried Yak skin glue powder that obtains of this glue;
(13) after 20 ~ 500g Radix Rehmanniae Preparata, 30 ~ 80g Radix Astragali, 50 ~ 400g Radix Angelicae Sinensis, 10 ~ 500g Fructus Jujubae, 10 ~ 300g Fructus Lycii, 20 ~ 400g Arillus Longan being mixed, press 3 ~ 10 water extraordinarily of mixture quality, in temperature, be to extract 1 ~ 4 time under the condition of 70 ~ 100 ℃, each extraction time is 1 ~ 4 hour, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 60 ~ 90 ℃, the spray-dried ingredient powder that obtains;
(14) described Yak skin glue powder is mixed homogeneously with described ingredient powder, granulate according to a conventional method.
Described step (1) or the alkali of described step in (4) refer to a kind of in sodium hydroxide solution, potassium hydroxide solution, sodium bicarbonate solution.
The protease of described step in is (6) a kind of in alkaline protease, papain, neutral protease, pepsin, trypsin.
Described step (12) with described step (13) in spray-dired condition refer to mist flow 20 ~ 25mL/min, 35 ~ 45 ℃ of feeding temperatures, 170 ~ 180 ℃ of inlet temperature.
The present invention compared with prior art has the following advantages:
1, the present invention has strengthened the process procedure of depilation, by alkaline process, is lost hair or feathers and is combined with mechanical rotary drum depilation, and depilation fast effectively.
2, the present invention has increased the processing step of defat, by enzyme process fast defat, adopts this processing step effectively to improve dissolubility.
3, the present invention has increased except foreign protein operation, by adding 2 ~ 20% alum solutions effectively to remove impurity and foreign protein.
4, the present invention, by the increase skin operation of scalding, adds crystal sugar, has effectively improved clarity.
5, the present invention has increased and has put forward foam operation, by adding 0 ~ 10 ℃ of pure water repeatedly to carry foam, obtains shinny glue juice.
6, the former technique glue by dynamic light scattering, the present invention being extracted carries out DLS mensuration, can find out that in former technique extract, molecular weight disperses, and has occurred 3 peaks.(referring to table 1, table 2, Fig. 1, Fig. 2).
Table 1 extracts former technique glue DLS measurement result
Note: Item is for to measure number of times to same batch sample.
Table 2 extracts former technique glue and measures different-grain diameter peak Distribution
7, by dynamic light scattering, new_type treatment gained sample of the present invention is carried out to DLS mensuration, can find out that molecular weight is concentrated, only have a peak.(referring to table 3, table 4, Fig. 3, Fig. 4).
Table 3 glue DLS of the present invention measurement result
Note: Item is for to measure number of times to same batch sample
Table 4 glue of the present invention is measured different-grain diameter peak Distribution
8, by dynamic light scattering, the present invention being beaten to foam colloid and carry out DLS mensuration, can find out that the residue molecular weight of dozen foam is larger, is the critical impurities that affects dissolubility and clarity.(referring to table 5, table 6, Fig. 5, Fig. 6).
Table 5 is beaten foam colloid DLS measurement result
Note: Item is for to measure number of times to same batch sample
Table 6 Jiao Droplets measures different-grain diameter peak Distribution
9, technique of the present invention is simple, with low cost.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the specific embodiment of the present invention is described in further detail.
Fig. 1 is that the percentage composition of the former technique glue of the present invention different radii collagen protein distributes.
Fig. 2 is that the present invention extracts former technique glue mensuration different-grain diameter content distribution.
Fig. 3 is that the percentage composition of glue different radii collagen protein of the present invention distributes.
Fig. 4 is that glue of the present invention is measured different-grain diameter content distribution.
Fig. 5 is that the percentage composition of Jiao Droplets different radii collagen protein of the present invention distributes.
Fig. 6 is that Jiao Droplets of the present invention measures different-grain diameter content distribution.
The specific embodiment
embodiment 1a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 3000g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 24 hours, then by 2 times of its weight, adding mass concentration is 0.5% alkali, in temperature, be to soak 72 hours under the condition of 20 ℃, obtain the yak skin after caustic dip.
Wherein: alkali refers to sodium hydroxide solution.
(2) the yak skin after caustic dip is put into electronic rotary drum, every 2 hours rotary drums, rotate 5 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers.
(3) the yak skin after once losing hair or feathers is added to water soaking by 3 times of its weight, after 2 hours, obtain the yak skin after dealkalize.
(4) the yak skin after dealkalize is cut into the bulk of 50cm, then by 2 times of its weight, adding mass concentration is 0.5% alkali, soak 72 hours under temperature is the condition of 20 ℃ after, insert in electric rotating drum, every 2 hours rotary drums, rotate 5 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation.
Wherein: alkali refers to sodium hydroxide solution.
(5) by the yak skin after secondary depilation, in water temperature, be to soak dealkalize 10 minutes under the condition of 20 ℃, then clear water rinses, and cleans remaining soft flocks, and measures pH value, obtains the yak skin of dealkalize depilation.
(6) in the yak skin of dealkalize depilation, adding the protease of its weight 0.2%, is defat 15 minutes under the condition of 30 ℃ in temperature, obtains the yak skin after defat.
Wherein: protease is alkaline protease.
(7) by scald skin 1 time of the water of 5 times of its quality for the yak skin after defat, wherein scald in the 1st temperature 50 C hot water skin 10 minutes, dewatering is placed half an hour, again change water, scald in 40 ℃ of water of the 2nd temperature skin 10 minutes, again change water, the skin 10 minutes of scalding in the 3rd temperature 50 C water, the yak skin that finally obtains scalding after skin.
(8) the yak skin of scalding after skin is extracted with the water of 8 times of its quality, after 2 hours, filter, discard residue, obtain filtrate A.
(9) after filtrate A being concentrated into proportion and being 1:1.1, adding mass concentration is 2% alum solution, stirs, and standing 12h at 25 ℃, then, at 5 ℃ of cold preservation 12h, removes by filter precipitate, obtains liquor B.
By liquor B when 60 ℃ are concentrated into proportion and are 1:1.3, add 0 ℃ of pure water to start to carry foam, repeatable operation 3 times, obtains water content and is 50% shinny glue juice.
(11) crystal sugar is filtered after the water dissolution by 3 times of its quality, obtain crystal sugar solution.
(12) in glue juice, add the crystal sugar solution of its volume 0.2%, stir, obtain glue, this glue is the spray-dried Yak skin glue powder that obtains under the condition of mist flow 20mL/min, 35 ℃ of feeding temperatures, 170 ℃ of inlet temperature.
(13) after 20g Radix Rehmanniae Preparata, the 30g Radix Astragali, 50g Radix Angelicae Sinensis, 10g Fructus Jujubae, 10g Fructus Lycii, 20g Arillus Longan being mixed, press 3 water extraordinarily of mixture quality, in temperature, be to extract 1 time under the condition of 70 ℃, each extraction time is 1 hour, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 60 ℃, the spray-dried ingredient powder that obtains under the condition of mist flow 20mL/min, 35 ℃ of feeding temperatures, 170 ℃ of inlet temperature.
(14) Yak skin glue powder is mixed homogeneously with ingredient powder, granulate according to a conventional method.
embodiment 2a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 5000g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 48 hours, then by 3 times of its weight, adding mass concentration is 10% alkali, in temperature, be to soak 24 hours under the condition of 38 ℃, obtain the yak skin after caustic dip.
Wherein: alkali refers to potassium hydroxide solution.
(2) the yak skin after caustic dip is put into electronic rotary drum, every 4 hours rotary drums, rotate 20 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers.
(3) the yak skin after once losing hair or feathers is added to water soaking by 5 times of its weight, after 4 hours, obtain the yak skin after dealkalize.
(4) the yak skin after dealkalize is cut into the bulk of 70cm, then by 3 times of its weight, adding mass concentration is 10% alkali, soak 24 hours under temperature is the condition of 38 ℃ after, insert in electric rotating drum, every 4 hours rotary drums, rotate 20 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation.
Wherein: alkali refers to potassium hydroxide solution.
(5) by the yak skin after secondary depilation, in water temperature, be to soak dealkalize under the condition of 30 ℃, repeat 4 times, each 30 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers.
(6) in the yak skin of dealkalize depilation, adding the protease of its weight 0.8%, is defat 3 minutes under the condition of 60 ℃ in temperature, obtains the yak skin after defat.
Wherein: protease is papain.
(7) by scald skin 3 times of the water of 20 times of its quality for the yak skin after defat, wherein scald in 80 ℃ of hot water of the 1st temperature skin 3 minutes, dewatering is placed half an hour, again change water, scald in the 2nd temperature 60 C water skin 5 minutes, again change water, the skin 3 minutes of scalding in 80 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin.
(8) the yak skin of scalding after skin is extracted with the water of 12 times of its quality, after 10 hours, filter, discard residue, obtain filtrate A.
(9) after filtrate A being concentrated into proportion and being 1:1.3, adding mass concentration is 10% alum solution, stirs, and standing 4h at 35 ℃, then, at 10 ℃ of cold preservation 6h, removes by filter precipitate, obtains liquor B.
By liquor B when 80 ℃ are concentrated into proportion and are 1:1.5, add 10 ℃ of pure water to start to carry foam, repeatable operation 8 times, obtains water content and is 70% shinny glue juice.
(11) crystal sugar is filtered after the water dissolution by 8 times of its quality, obtain crystal sugar solution.
(12) in glue juice, add the crystal sugar solution of its volume 0.5%, stir, obtain glue, this glue is the spray-dried Yak skin glue powder that obtains under the condition of mist flow 25mL/min, 45 ℃ of feeding temperatures, 180 ℃ of inlet temperature.
(13) after 500g Radix Rehmanniae Preparata, the 80g Radix Astragali, 400g Radix Angelicae Sinensis, 500g Fructus Jujubae, 300g Fructus Lycii, 400g Arillus Longan being mixed, press 10 water extraordinarily of mixture quality, in temperature, be to extract 4 times under the condition of 100 ℃, each extraction time is 4 hours, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 90 ℃, the spray-dried ingredient powder that obtains under the condition of mist flow 25mL/min, 45 ℃ of feeding temperatures, 180 ℃ of inlet temperature.
(14) Yak skin glue powder is mixed homogeneously with ingredient powder, granulate according to a conventional method.
embodiment 3a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 4000g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 36 hours, then by 2.5 times of its weight, adding mass concentration is 5% alkali, in temperature, be to soak 48 hours under the condition of 28 ℃, obtain the yak skin after caustic dip.
Wherein: alkali refers to sodium bicarbonate solution.
(2) the yak skin after caustic dip is put into electronic rotary drum, every 3 hours rotary drums, rotate 15 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers.
(3) the yak skin after once losing hair or feathers is added to water soaking by 4 times of its weight, after 3 hours, obtain the yak skin after dealkalize.
(4) the yak skin after dealkalize is cut into the bulk of 60cm, then by 2.5 times of its weight, adding mass concentration is 5% alkali, soak 48 hours under temperature is the condition of 28 ℃ after, insert in electric rotating drum, every 3 hours rotary drums, rotate 15 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation.
Wherein: alkali refers to sodium bicarbonate solution.
(5) by the yak skin after secondary depilation, in water temperature, be to soak dealkalize under the condition of 25 ℃, repeat 2 times, each 20 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers.
(6) in the yak skin of dealkalize depilation, adding the protease of its weight 0.5%, is defat 9 minutes under the condition of 45 ℃ in temperature, obtains the yak skin after defat.
Wherein: protease is neutral protease.
(7) by scald skin 2 times of the water of 15 times of its quality for the yak skin after defat, wherein scald in 65 ℃ of hot water of the 1st temperature skin 6 minutes, dewatering is placed half an hour, again change water, scald in the 2nd temperature 50 C water skin 7 minutes, again change water, the skin 6 minutes of scalding in 75 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin.
(8) the yak skin of scalding after skin is extracted with the water of 10 times of its quality, after 6 hours, filter, discard residue, obtain filtrate A.
(9) after filtrate A being concentrated into proportion and being 1:1.2, adding mass concentration is 6% alum solution, stirs, and standing 8h at 30 ℃, then, at 8 ℃ of cold preservation 9h, removes by filter precipitate, obtains liquor B.
By liquor B when 70 ℃ are concentrated into proportion and are 1:1.4, add 5 ℃ of pure water to start to carry foam, repeatable operation 5 times, obtains water content and is 60% shinny glue juice.
(11) crystal sugar is filtered after the water dissolution by 5 times of its quality, obtain crystal sugar solution.
(12) in glue juice, add the crystal sugar solution of its volume 0.3%, stir, obtain glue, this glue is the spray-dried Yak skin glue powder that obtains under the condition of mist flow 22mL/min, 40 ℃ of feeding temperatures, 175 ℃ of inlet temperature.
(13) after 250g Radix Rehmanniae Preparata, the 50g Radix Astragali, 250g Radix Angelicae Sinensis, 250g Fructus Jujubae, 150g Fructus Lycii, 200g Arillus Longan being mixed, press 6 water extraordinarily of mixture quality, in temperature, be to extract 2 times under the condition of 80 ℃, each extraction time is 2 hours, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 80 ℃, the spray-dried ingredient powder that obtains under the condition of mist flow 22mL/min, 40 ℃ of feeding temperatures, 175 ℃ of inlet temperature.
(14) Yak skin glue powder is mixed homogeneously with ingredient powder, granulate according to a conventional method.
embodiment 4a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 3500g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 30 hours, then by 2 times of its weight, adding mass concentration is 2% alkali, in temperature, be to soak 36 hours under the condition of 25 ℃, obtain the yak skin after caustic dip.
Wherein: alkali refers to sodium hydroxide solution.
(2) the yak skin after caustic dip is put into electronic rotary drum, every 2 hours rotary drums, rotate 5 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers.
(3) the yak skin after once losing hair or feathers is added to water soaking by 3.5 times of its weight, after 2 hours, obtain the yak skin after dealkalize.
(4) the yak skin after dealkalize is cut into the bulk of 50cm, then by 2 times of its weight, adding mass concentration is 2% alkali, soak 36 hours under temperature is the condition of 25 ℃ after, insert in electric rotating drum, every 2 hours rotary drums, rotate 5 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation.
Wherein: alkali refers to sodium hydroxide solution.
(5) by the yak skin after secondary depilation, in water temperature, be to soak dealkalize under the condition of 22 ℃, repeat 3 times, each 15 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers.
(6) in the yak skin of dealkalize depilation, adding the protease of its weight 0.4%, is defat 5 minutes under the condition of 40 ℃ in temperature, obtains the yak skin after defat.
Wherein: protease is pepsin.
(7) by scald skin 1 time of the water of 8 times of its quality for the yak skin after defat, wherein scald in 55 ℃ of hot water of the 1st temperature skin 5 minutes, dewatering is placed half an hour, again change water, scald in the 2nd temperature 45 C water skin 6 minutes, again change water, the skin 5 minutes of scalding in 55 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin.
(8) the yak skin of scalding after skin is extracted with the water of 9 times of its quality, after 4 hours, filter, discard residue, obtain filtrate A.
(9) after filtrate A being concentrated into proportion and being 1:1.1, adding mass concentration is 4% alum solution, stirs, and standing 6h at 28 ℃, then, at 6 ℃ of cold preservation 10h, removes by filter precipitate, obtains liquor B.
By liquor B when 65 ℃ are concentrated into proportion and are 1:1.3, add 4 ℃ of pure water to start to carry foam, repeatable operation 4 times, obtains water content and is 55% shinny glue juice.
(11) crystal sugar is filtered after the water dissolution by 4 times of its quality, obtain crystal sugar solution.
(12) in glue juice, add the crystal sugar solution of its volume 0.3%, stir, obtain glue, this glue is the spray-dried Yak skin glue powder that obtains under the condition of mist flow 20mL/min, 35 ℃ of feeding temperatures, 170 ℃ of inlet temperature.
(13) after 100g Radix Rehmanniae Preparata, the 60g Radix Astragali, 100g Radix Angelicae Sinensis, 100g Fructus Jujubae, 100g Fructus Lycii, 100g Arillus Longan being mixed, press 4 water extraordinarily of mixture quality, in temperature, be to extract 1 time under the condition of 75 ℃, each extraction time is 1 hour, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 65 ℃, the spray-dried ingredient powder that obtains under the condition of mist flow 20mL/min, 35 ℃ of feeding temperatures, 170 ℃ of inlet temperature.
(14) Yak skin glue powder is mixed homogeneously with ingredient powder, granulate according to a conventional method.
embodiment 5a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 4500g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 40 hours, then by 3 times of its weight, adding mass concentration is 8% alkali, in temperature, be to soak 60 hours under the condition of 36 ℃, obtain the yak skin after caustic dip.
Wherein: alkali refers to potassium hydroxide solution.
(2) the yak skin after caustic dip is put into electronic rotary drum, every 3 hours rotary drums, rotate 15 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers.
(3) the yak skin after once losing hair or feathers is added to water soaking by 5 times of its weight, after 4 hours, obtain the yak skin after dealkalize.
(4) the yak skin after dealkalize is cut into the bulk of 70cm, then by 3 times of its weight, adding mass concentration is 8% alkali, soak 60 hours under temperature is the condition of 36 ℃ after, insert in electric rotating drum, every 3 hours rotary drums, rotate 15 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation.
Wherein: alkali refers to potassium hydroxide solution.
(5) by the yak skin after secondary depilation, in water temperature, be to soak dealkalize under the condition of 28 ℃, repeat 3 times, each 25 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers.
(6) in the yak skin of dealkalize depilation, adding the protease of its weight 0.6%, is defat 10 minutes under the condition of 50 ℃ in temperature, obtains the yak skin after defat.
Wherein: protease is trypsin.
(7) by scald skin 2 times of the water of 15 times of its quality for the yak skin after defat, wherein scald in 75 ℃ of hot water of the 1st temperature skin 8 minutes, dewatering is placed half an hour, again change water, scald in the 2nd temperature 50 C water skin 8 minutes, again change water, the skin 5 minutes of scalding in 75 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin.
(8) the yak skin of scalding after skin is extracted with the water of 11 times of its quality, after 8 hours, filter, discard residue, obtain filtrate A.
(9) after filtrate A being concentrated into proportion and being 1:1.3, adding mass concentration is 8% alum solution, stirs, and standing 10h at 32 ℃, then, at 8 ℃ of cold preservation 10h, removes by filter precipitate, obtains liquor B.
By liquor B when 75 ℃ are concentrated into proportion and are 1:1.5, add 8 ℃ of pure water to start to carry foam, repeatable operation 7 times, obtains water content and is 65% shinny glue juice.
(11) crystal sugar is filtered after the water dissolution by 7 times of its quality, obtain crystal sugar solution.
(12) in glue juice, add the crystal sugar solution of its volume 0.4%, stir, obtain glue, this glue is the spray-dried Yak skin glue powder that obtains under the condition of mist flow 24mL/min, 42 ℃ of feeding temperatures, 178 ℃ of inlet temperature.
(13) after 300g Radix Rehmanniae Preparata, the 70g Radix Astragali, 300g Radix Angelicae Sinensis, 300g Fructus Jujubae, 200g Fructus Lycii, 300g Arillus Longan being mixed, press 9 water extraordinarily of mixture quality, in temperature, be to extract 3 times under the condition of 90 ℃, each extraction time is 3 hours, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 85 ℃, the spray-dried ingredient powder that obtains under the condition of mist flow 24mL/min, 42 ℃ of feeding temperatures, 178 ℃ of inlet temperature.
(14) Yak skin glue powder is mixed homogeneously with ingredient powder, granulate according to a conventional method.
Claims (4)
1. a method of improving Yak skin glue dissolubility, clarity, comprises the following steps:
(1) yak skin 3000 ~ 5000g is fresh or the dry Qinghai-Tibet Platean peculiar cattle kind yak wild yak after infiltrating, softening cleans up, fleshing is also soaked in water 24 ~ 48 hours, then by 2 ~ 3 times of its weight, adding mass concentration is 0.5 ~ 10% alkali, in temperature, be to soak 24 ~ 72 hours under the condition of 20 ~ 38 ℃, obtain the yak skin after caustic dip;
(2) the yak skin after described caustic dip is put into electronic rotary drum, every 2 ~ 4 hours rotary drums, rotate 5 ~ 20 minutes, carry out one-time mechanical depilation, the yak skin after once being lost hair or feathers;
(3) the yak skin after described once depilation is added to water soaking by 3 ~ 5 times of its weight, after 2 ~ 4 hours, obtain the yak skin after dealkalize;
(4) the yak skin after described dealkalize is cut into the bulk of 50 ~ 70cm, then by 2 ~ 3 times of its weight, adding mass concentration is 0.5 ~ 10% alkali, soak 24 ~ 72 hours under temperature is the condition of 20 ~ 38 ℃ after, insert in described electronic rotary drum, every 2 ~ 4 hours rotary drums, rotate 5 ~ 20 minutes, carry out secondary mechanical depilation, obtain the yak skin after secondary depilation;
(5) by the yak skin after the depilation of described secondary, in water temperature, be to soak dealkalize under the condition of 20 ~ 30 ℃, repeat 1 ~ 4 time, each 10 ~ 30 minutes, then clear water rinsed, and cleaned remaining soft flocks, and measured pH value, obtained the yak skin that dealkalize is lost hair or feathers;
(6) in the yak skin of described dealkalize depilation, adding the protease of its weight 0.2 ~ 0.8%, is defat 3 ~ 15 minutes under the condition of 30 ~ 60 ℃ in temperature, obtains the yak skin after defat;
(7) by scald skin 1 ~ 3 time of the water of 5 ~ 20 times of its quality for the yak skin after described defat, wherein scald in 50 ~ 80 ℃ of hot water of the 1st temperature skin 3 ~ 10 minutes, dewatering is placed half an hour, again change water, scald in 40 ~ 60 ℃ of water of the 2nd temperature skin 5 ~ 10 minutes, again change water, the skin 3 ~ 10 minutes of scalding in 50 ~ 80 ℃ of water of the 3rd temperature, the yak skin that finally obtains scalding after skin;
(8) described yak skin of scalding after skin is extracted with the water of 8 ~ 12 times of its quality, after 2 ~ 10 hours, filter, discard residue, obtain filtrate A;
(9) after described filtrate A being concentrated into proportion and being 1:1.1 ~ 1:1.3, adding mass concentration is 2 ~ 10% alum solution, stirs, and standing 4 ~ 12h at 25 ~ 35 ℃, then, at 5 ~ 10 ℃ of cold preservation 6 ~ 12h, removes by filter precipitate, obtains liquor B;
By described liquor B when 60 ~ 80 ℃ are concentrated into proportion and are 1:1.3 ~ 1:1.5, add 0 ~ 10 ℃ of pure water to start to carry foam, repeatable operation 3 ~ 8 times, obtains water content and is 50 ~ 70% shinny glue juice;
(11) crystal sugar is filtered after the water dissolution by 3 ~ 8 times of its quality, obtain crystal sugar solution;
(12) in described glue juice, add the described crystal sugar solution of its volume 0.2 ~ 0.5%, stir, obtain glue, the spray-dried Yak skin glue powder that obtains of this glue;
(13) after 20 ~ 500g Radix Rehmanniae Preparata, 30 ~ 80g Radix Astragali, 50 ~ 400g Radix Angelicae Sinensis, 10 ~ 500g Fructus Jujubae, 10 ~ 300g Fructus Lycii, 20 ~ 400g Arillus Longan being mixed, press 3 ~ 10 water extraordinarily of mixture quality, in temperature, be to extract 1 ~ 4 time under the condition of 70 ~ 100 ℃, each extraction time is 1 ~ 4 hour, merge and obtain extracting solution, it is 1:1.5 that this extracting solution is concentrated into proportion at 60 ~ 90 ℃, the spray-dried ingredient powder that obtains;
(14) described Yak skin glue powder is mixed homogeneously with described ingredient powder, granulate according to a conventional method.
2. a kind of method of improving Yak skin glue dissolubility, clarity as claimed in claim 1, is characterized in that: described step (1) or the alkali of described step in (4) refer to a kind of in sodium hydroxide solution, potassium hydroxide solution, sodium bicarbonate solution.
3. a kind of method of improving Yak skin glue dissolubility, clarity as claimed in claim 1, is characterized in that: the protease of described step in is (6) a kind of in alkaline protease, papain, neutral protease, pepsin, trypsin.
4. a kind of method of improving Yak skin glue dissolubility, clarity as claimed in claim 1, it is characterized in that: described step (12) with described step (13) in spray-dired condition refer to mist flow 20 ~ 25mL/min, 35 ~ 45 ℃ of feeding temperatures, 170 ~ 180 ℃ of inlet temperature.
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| CN201410246381.1A CN104000847A (en) | 2014-06-05 | 2014-06-05 | Method for improving solubility and clarity of Maoxijiao |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105147727A (en) * | 2015-09-21 | 2015-12-16 | 西南科技大学 | Preparation method of Qinghai-Tibet plateau yak skin colla corii asini |
| CN107412268A (en) * | 2016-12-29 | 2017-12-01 | 青海高原红绿色保健制品有限公司 | A kind of Yak skin glue and preparation method thereof |
| CN109287970A (en) * | 2018-12-03 | 2019-02-01 | 重庆明海食品有限公司 | A kind of preparation method of instant halogen pork head meat |
| CN109315767A (en) * | 2018-08-31 | 2019-02-12 | 河北共永生物科技有限公司 | A kind of formula and its preparation process of Islamic oxhide gelatin |
| CN112426483A (en) * | 2020-12-03 | 2021-03-02 | 中国科学院西北高原生物研究所 | Compound yak hide product with blood replenishing effect and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147727A (en) * | 2015-09-21 | 2015-12-16 | 西南科技大学 | Preparation method of Qinghai-Tibet plateau yak skin colla corii asini |
| CN107412268A (en) * | 2016-12-29 | 2017-12-01 | 青海高原红绿色保健制品有限公司 | A kind of Yak skin glue and preparation method thereof |
| CN109315767A (en) * | 2018-08-31 | 2019-02-12 | 河北共永生物科技有限公司 | A kind of formula and its preparation process of Islamic oxhide gelatin |
| CN109287970A (en) * | 2018-12-03 | 2019-02-01 | 重庆明海食品有限公司 | A kind of preparation method of instant halogen pork head meat |
| CN112426483A (en) * | 2020-12-03 | 2021-03-02 | 中国科学院西北高原生物研究所 | Compound yak hide product with blood replenishing effect and preparation method thereof |
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