CN1039878C - Chewing medicinal piece of shiquan dabu Wan and the prepn. method - Google Patents

Chewing medicinal piece of shiquan dabu Wan and the prepn. method Download PDF

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Publication number
CN1039878C
CN1039878C CN94110512A CN94110512A CN1039878C CN 1039878 C CN1039878 C CN 1039878C CN 94110512 A CN94110512 A CN 94110512A CN 94110512 A CN94110512 A CN 94110512A CN 1039878 C CN1039878 C CN 1039878C
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China
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shiquan dabu
excipient
dabu
shiquan
fen
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Expired - Lifetime
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CN94110512A
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CN1122689A (en
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黄贤琦
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Individual
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Abstract

The present invention relates to a preparation method for preparing a Chinese patent medicinal chewing block preparation and a preparation by mixing Chinese herbal medicinal fine powder and an excipient. The preparation is based on a recipe of a perfect major supplementation pill of the Chinese pharmacopoeia of the 90 edition; firstly, medicinal material is pulverized into perfect major supplementation powder and is mixed with excipient milk powder, refined powder, edible vegetable oil, sugar, a foaming agent, spice and water; a machine is used for pressing a mould for molding; then, a molded material blank is placed in a roasting device of 175 to 220 DEG C for roasting the molded material blank for 5 to 20 minutes to obtain a perfect major supplementation chewing block. The medicine has the advantages of original recipe, original medicine, reliable therapeutic effect, wide purposes, plain and thin medicinal tastes, fragrant and brittle mouth feel, convenient administration, stable properties, convenient storage, etc.

Description

Chewing medicinal piece of shiquan dabu Wan and preparation method thereof
The present invention relates to a kind of Chinese herbal medicine fine powder and mixed with excipients used, the Chinese patent medicine of then making is chewed the preparation method of piece and preparation thereof.
Bolus of ten powerful tonics is famous benefiting qi and nourishing blood medicine.It sees Song dynasty " formulary of peaceful benevolent dispensary " volume five " decoction of ten powerful tonics " side the earliest, and the back is recorded by 85 editions pharmacopeia of China and 90 editions pharmacopeia.This medical instrument has the effect of significant temperature compensation QI and blood, is usually used in QI and blood deficiency, pale complexion, the treatment of disease such as the cardiopalmus of breathing hard, dizzy spontaneous perspiration, fatigue and asthenia, extremity are not warm, menorrhagia.90 editions contained medicines of pharmacopeia consist of: Radix Codonopsis 80g, the Rhizoma Atractylodis Macrocephalae (stir-fry) 80g, Poria 80g, Radix Glycyrrhizae (processed with honey) 40g, Radix Angelicae Sinensis 120g, Rhizoma Chuanxiong 40g, Radix Paeoniae Alba (wine stir-fry) 80g, Radix Rehmanniae Preparata 120g, the Radix Astragali (processed with honey) 80g, Cortex Cinnamomi 20g.Traditional method is that above-mentioned ten herbal medicines are ground into fine powder in proportion, sieve, and forms SHIQUAN DABU FEN, makes bolus of ten powerful tonics with Mel as excipient then.For a long time, this pill agent exists all the time that flavour of a drug are dense, mouthfeel is poor, dose is big, absorbs slowly, is not easy to sterilization, the shortcoming such as go mouldy that is easy to damage by worms, and brings great inconvenience for clinical practice and industrialized mass.
The objective of the invention is in order to overcome above-mentioned deficiency, for society provides that a kind of flavour of a drug are thin, mouthfeel delicious and crisp, taking convenience, absorb fully, stable in properties is convenient to novel Chinese patent medicine preparation--the chewing medicinal piece of shiquan dabu Wan of mass industrialized production simultaneously.
The present invention is achieved in that the dosage 100 with SHIQUAN DABU FEN is benchmark, its adjuvant is respectively: milk powder 8-16%, smart powder 180-260%, edible vegetable oil 44-55%, sugared 45-60%, sodium bicarbonate 1.8-2.8%, ammonium bicarbonate 4.8-8.4%, cream flavour 0.2-0.6%, vanillin 0.6-1.2%, water 100-200%, at first Radix Rehmanniae Preparata, Radix Glycyrrhizae Preparata, Radix Astragali Preparata are placed in the baking oven, 60 ℃ of bakings as for.And then Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Poria, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba (parched with wine), Cortex Cinnamomi become fine powder with three medicine pulverize separately of above baking, cross sieve No. six, after the weighing mix homogeneously SHIQUAN DABU FEN.Get edible vegetable oil, cream flavour places to stir in the dosage container and is A liquid; In another dosage container, add water, vanillin, sugar, ammonium bicarbonate stirring and dissolving, and then with milk powder, the back that stirs is B liquid; Take by weighing SHIQUAN DABU FEN, smart powder and sodium bicarbonate, put into spice container and mix, under agitation slowly add earlier A liquid, the B liquid that adds that continues is modulated the medicine soft material, makes it to become agglomerating promptly the loosing of touching of holding and is degree.At last soft material is put into the mould pressing mold and be shaped, material base is sent in the 175-220 ℃ of temperature toasted 5-20 minute, take out cooling, inspection, packing promptly.
The milk powder that the present invention added is the milk powder goods that meet national standard, preferably adopts the above high-grade milk powder of one-level or one-level.Milk powder has seasoning, improves mouthfeel, dilutes medicated powder in chewing medicinal piece of shiquan dabu Wan effect.
Smart powder of the present invention is the wheat flour that meets national standard, preferably uses purified superfine wheat flour.This essence powder also refers to be similar to the flour of other grains of wheat flour, as millet powder, rice meal, Semen Maydis powder etc.Smart powder has dilution medicated powder in chewing medicinal piece of shiquan dabu Wan, the desalination flavour of a drug improve the effect of mouthfeel.
Vegetable oil of the present invention is meant the Oleum Arachidis hypogaeae semen that meets national standard.This vegetable oil also refers to be similar to other edible oil of Oleum Arachidis hypogaeae semen, and as Oleum Glycines, Oleum Brassicae campestris, vegetable oil has certain adhesive effect at chewing medicinal piece of shiquan dabu Wan, and can improve the fragility and the shortcake of chewing medicinal piece of shiquan dabu Wan, makes this medicine more crisp, fragrant and pleasant to taste.
Sugar of the present invention is meant sucrose or the brown sugar that meets national standard.It also can be the xylitol that meets national standard.Sugar has seasoning in chewing medicinal piece of shiquan dabu Wan, improve the effect of mouthfeel, and can improve the fragility of finished product.
Ammonium bicarbonate of the present invention is meant the ammonium bicarbonate that meets national food sanitation standard, and sodium bicarbonate is meant the sodium bicarbonate that meets national medicinal standard, and they are jointly as foaming agent, makes the chewing medicinal piece of shiquan dabu Wan tissue looseness after the baking good to eat, easy to use.
Cream flavour and vanillin that the present invention adds all should meet national food sanitation standard, and they mainly play the seasoning effect in chewing medicinal piece of shiquan dabu Wan.
The present invention also can add excipient such as an amount of dextrin, sodium chloride, the auxiliary seasoning effect of performance.
Of the present invention shape can be multiple shapes such as rectangle, square, circle, triangle, cylindricality.
Of the present invention weight is changeable, be degree to make things convenient for the patient to take, but the piece number of at every turn taking must contain the SHIQUAN DABU FEN of 4.5g ± 5%, to guarantee therapeutic efficiency.
The present invention is through the repeatedly middle trial production of GPA ORLAND1200 type composite production line (Italy makes), and detect according to the quality standard of interrelated data, its quality all reaches the standard of expection, because scientific formulation of the present invention, the dosage form novelty, technology advanced person, of many uses, so chewing medicinal piece of shiquan dabu Wan possesses following advantage:
1, the former medicine of former side, curative effect are reliable;
2, thin, the mouthfeel delicious and crisp of flavour of a drug, taking convenience;
3, effect is rapid, absorption is complete;
4, stable in properties, be difficult for to pollute, be convenient to deposit.

Claims (5)

1, chewing medicinal piece of shiquan dabu Wan comprises SHIQUAN DABU FEN and excipient, it is characterized in that: it be by SHIQUAN DABU FEN and excipient through mixing, suppress, toast the block of making, said excipient is milk powder, smart powder, edible vegetable oil, sugar, ammonium bicarbonate, sodium bicarbonate, cream flavour, vanillin and water.
2, chewing medicinal piece of shiquan dabu Wan according to claim 1, the dosage that it is characterized in that excipient should be respectively the following percentage ratio of SHIQUAN DABU FEN: milk powder 8-16%, smart powder 180-260%, edible vegetable oil 44-55%, sugared 45-60%, sodium bicarbonate 1.6-2.8%, ammonium bicarbonate 4.8-8.4%, cream flavour 0.2-0.6%, vanillin 0.6-1.2%, water 100-200%.
3, chewing medicinal piece of shiquan dabu Wan according to claim 1 and 2 is characterized in that said sugar is xylitol or sucrose.
4, the preparation method of chewing medicinal piece of shiquan dabu Wan according to claim 1 and 2, it is characterized in that SHIQUAN DABU FEN and mixed with excipients, and press forming, place 175 ℃-220 ℃ temperature to toast the medicinal piece of shiquan dabu material base of molding, its stoving time is 5-20 minute.
5, the preparation method of chewing medicinal piece of shiquan dabu Wan according to claim 4 is characterized in that the dissolving of SHIQUAN DABU FEN and excipient, and hybrid technique should be: edible vegetable oil and cream flavour are placed in the dosage container, and the back that stirs is A liquid; In another container, add water, vanillin, sugar, ammonium bicarbonate stirring and dissolving, be B liquid after stirring with milk powder then; Take by weighing SHIQUAN DABU FEN, smart powder and sodium bicarbonate, put into the spice container mix homogeneously, under agitation at first add A liquid, the B liquid that adds that continues is modulated the medicine soft material, and making becomes hold agglomerating, and promptly loosing of touching is degree, and last machine press mold is shaped, and toasts to get final product.
CN94110512A 1994-03-28 1994-03-28 Chewing medicinal piece of shiquan dabu Wan and the prepn. method Expired - Lifetime CN1039878C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN94110512A CN1039878C (en) 1994-03-28 1994-03-28 Chewing medicinal piece of shiquan dabu Wan and the prepn. method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN94110512A CN1039878C (en) 1994-03-28 1994-03-28 Chewing medicinal piece of shiquan dabu Wan and the prepn. method

Publications (2)

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CN1122689A CN1122689A (en) 1996-05-22
CN1039878C true CN1039878C (en) 1998-09-23

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108741076A (en) * 2018-05-25 2018-11-06 李红光 A kind of nourishing qi and blood chewable tablets
CN113101219B (en) * 2021-05-19 2023-11-10 河北太行农牧供应链有限公司 Traditional Chinese medicine pill making machine with function of removing smell of pills and using method of traditional Chinese medicine pill making machine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中华人民共和国药典 1990.1.1 编写组,人民卫生出版社 *

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