CN103977387A - Traditional Chinese medicinal preparation for treating cerebral thrombosis and preparation method thereof - Google Patents
Traditional Chinese medicinal preparation for treating cerebral thrombosis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating cerebral thrombosis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. Effective components in the traditional Chinese medicinal preparation are prepared from the following raw materials: benzoin, Chinese azalea fruit, chloranthus japonicus, martianus dermestoides chevr, veronicastrum herb, camphor root, nude fern herb, mioga ginger, henbit, crinite pogonatherum herb, Japanese ladyslipper herb with root, divaricate saposhnikovia root, potentilla chinensis, rhizoma arisaematis, style pachysandra herb and mustard. The traditional Chinese medicinal preparation is prepared from compatible medicinal materials, accords with traditional Chinese medicine and modern medical theory, has the effects of dispelling wind and eliminating dampness, regulating qi circulation and activating blood, eliminating stasis to subdue swelling and protecting liver and bile, is convenient to use and good in absorption effect, does not have adverse or toxic or side effects. Clinical verification proves that the traditional Chinese medicinal preparation has extremely good relieving and treating effects on cerebral thrombosis and thrombus extension control, and is suitable for cerebral thrombosis clinical treatment and nursing popularization and application.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of cerebral thrombosis.
Background technology
Cerebral thrombosis refers to and along blood circulation, enters cerebral arteries system because of abnormal solid-state, liquid, gaseous substance (being known as embolus), cause that arterial lumen is inaccessible, cause the necrosis of this tremulous pulse blood supply district local brain tissue, show as clinically hemiplegia, hemianesthesia, the speech office's source property neurologic impairment symptom occurring suddenly such as unclear.This disease accounts for 15～20% of cerebrovascular.Modal embolus derives from heart, 14～48% Patients With Rheumatic Valvular Disease generation cerebral embolism; When myocardial infarction, endocarditis, atrial fibrillation, operation on heart, easily bring out primary disease; Non-heart source property embolus sees that carotid artery atherosclerosis comes off, exogenous injury or pneumothorax, diving or high-altitude flight inadequate decompression, anemia of pregnant woman produce etc.
Cerebral thrombosis morbidity cause is divided into heart source property and non-heart source property.Heart source property is the most common, accounts for normally one of cardiopathic important behaviour of 60%～75%. cerebral embolism of cerebral embolism.The most common immediate cause is Chronic Atrial Fibrillation; In adolescence, rheumatic heart tumor is still the major reason of complicated with brain thromboembolism; Inflammatory vegetation during infective endocarditis on valve comes off.Myocardial infarction or myocardiac mural thrombus, mitral valve prolapse, myxoma of heart and cardiac operation and issue licence etc. and also often to cause.Septal defect person is stopped up in Congenital Heart ward, from the embolus of Venous system, also can cause crossed embolism.
Non-heart source property is rare, and atheromatous plaque and the attachment of aortic arch and the trunk that sends thereof come off, the thromboembolism that can cause, and pulmonary vein thrombosis or blood clot, pulmonary infection, septicemia also etc. can cause cerebral embolism.
The harm of cerebral thrombosis is that it is a kind of of ischemic cerebrovascular, is more common in middle-aged and elderly people greatly.Mainly that pathological changes due to cerebrovascular wall itself causes.The slight person of cerebral thrombosis shows as that a side limb activity is dumb, insensitive, error, and severe patient can occur that stupor, gatism are even dead.Most patients disease is front without any prodrome, unexpected onset in activity, PD is to summit within several seconds or several minutes for most symptoms, and small number of patients is ladder sample or the deterioration of carrying out property within a couple of days, during about half patient onset, sicken for consciousness, but the persistent period is of short duration.Cerebral embolism majority occurs in Internal Carotid System, and particularly middle cerebral artery is the most common, and the delayed ischemic neurological deficits that thromboembolism causes depends on embolus number, and can there be headache at scope and position during Acute onset, dizziness or limitation pain.
At present, treatment cerebral thrombosis is definitely not effective medicine also, and along with the development of medical science, acupuncture has curative effect significantly for treatment cerebral thrombosis.After the physical therapy that applies acupuncture, patient also can carry out auxiliary treatment by ancillary drug conventionally, but existing medicament categories is mixed and disorderly, and some patient occurs the problems such as skin allergy after using.Chinese materia medica, as the traditional medicine of China, has by advantages such as strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, if therefrom develop a kind of medicine, replaces existing medicine to have very significant curative effect for cerebral thrombosis.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of cerebral thrombosis; The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine theoretical, the effect with expelling wind and removing dampness, vital energy regualting and blood circulation-promoting, dissipating blood stasis for subsidence of swelling, hepatic cholagogic, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, cerebral thrombosis, the expansion of control thrombosis are had to fabulous alleviation and therapeutic effect, be suitable for cerebral thrombosis clinical treatment and nursing and apply.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for cerebral thrombosis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
52～82 parts of 54～84 parts of Martianus dermestoides Chevr. of 56～86 parts of Herba chloranthi japonicis of 59～89 parts of Fructus Rhododendri Molliss of Benzoinum
39～69 parts of 44～74 parts of Herba Psiloti Nudis of 49～79 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 41～71 Fen Rhizoma zingiberis miogae
30～60 parts of 32～62 parts of Radix Saposhnikoviaes of 34～64 parts of Herba cypripedii japonici of 37～67 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
19～49 parts, 24～54 parts of Semen Sinapiss of 25～55 parts of Herba Pachysandrae Stylosaes of 29～59 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
74 parts of 76 parts of Martianus dermestoides Chevr. of 78 parts of Herba chloranthi japonicis of 81 parts of Fructus Rhododendri Molliss of Benzoinum
61 parts of 66 parts of Herba Psiloti Nudis of 71 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 64 Fen Rhizoma zingiberis miogae
52 parts of 54 parts of Radix Saposhnikoviaes of 56 parts of Herba cypripedii japonici of 60 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
41 parts, 46 parts of Semen Sinapiss of 47 parts of Herba Pachysandrae Stylosaes of 51 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
67 parts of 69 parts of Martianus dermestoides Chevr. of 71 parts of Herba chloranthi japonicis of 74 parts of Fructus Rhododendri Molliss of Benzoinum
54 parts of 59 parts of Herba Psiloti Nudis of 64 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 57 Fen Rhizoma zingiberis miogae
45 parts of 47 parts of Radix Saposhnikoviaes of 49 parts of Herba cypripedii japonici of 53 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
34 parts, 39 parts of Semen Sinapiss of 40 parts of Herba Pachysandrae Stylosaes of 44 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
60 parts of 62 parts of Martianus dermestoides Chevr. of 63 parts of Herba chloranthi japonicis of 67 parts of Fructus Rhododendri Molliss of Benzoinum
47 parts of 52 parts of Herba Psiloti Nudis of 57 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 49 Fen Rhizoma zingiberis miogae
38 parts of 41 parts of Radix Saposhnikoviaes of 42 parts of Herba cypripedii japonici of 43 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
27 parts, 32 parts of Semen Sinapiss of 32 parts of Herba Pachysandrae Stylosaes of 37 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
Treat a preparation method for the Chinese medicine preparation of cerebral thrombosis, comprise following processing step:
(1) get Benzoinum, Herba chloranthi japonici, Herba cypripedii japonici and Rhizoma Arisaematis and remove impurity, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) after Fructus Rhododendri Mollis, Herba veronicastri villosuli, Herba pogonatheri criniti and Herba Potentillae Chinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, standby;
(3) Martianus dermestoides Chevr., Radix Cinnamomi Camphorae, Herba Psiloti Nudi and Semen Sinapis are put in container, added the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.13, dry, standby;
(4) Qu Rhizoma zingiberis miogae, Herba Lamii Amplexicaulis, Radix Saposhnikoviae and Herba Pachysandrae Stylosae are mixed thoroughly vexed with saline, with the micro-stir-fry of little fire, taking-up is dried, and are placed in mortar and grind into powder, cross 200 order fine powders, standby;
(5) thick paste of the fine powder of step (1), step (2), step (4) gained and step (3) gained is made to capsule, be the Chinese medicine preparation for the treatment of cerebral thrombosis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Benzoinum: acrid in the mouth, hardship, property is flat; GUIXIN, spleen channel.Open and steal clear god, promoting flow of QI and blood, pain relieving.For apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, puerperal blood faints, infantile convulsion.< < Bencao Congxin > > carries: " a surname's qi and blood circulation promotion.Grind and take the promoting the circulation of blood therapeutic method to keep the adverse QI flowing downwards, calm the nerves.”
Fructus Rhododendri Mollis: puckery, hardship, warm in nature, poisonous.Wind-expelling pain-stopping, dissipating blood stasis for subsidence of swelling.For anemofrigid-damp arthralgia, severe and migratory arthralgia pain, traumatic injury, carbuncle furunculosis.< < Bencao Congxin > > carries: " a surname, promoting the circulation of blood.Control anemofrigid-damp arthralgia, severe and migratory arthralgia swelling, flutters damage pain.”
Herba chloranthi japonici: acrid in the mouth, hardship, warm in nature, poisonous.Cold expelling dispels the wind, clots absorbing removing toxic substances.For cough due to wind and cold, women's amenorrhea, pruritus due to wind pathogen traumatic injury, carbuncle furuncle.< < Fujian traditional herbal medicine > > carries: " removing blood stasis and activating blood flow, heat-clearing and toxic substances removing.”
Martianus dermestoides Chevr.: acrid in the mouth, sweet, warm in nature; Return stomach, lung, large intestine channel.Warming middle-JIAO is regulated the flow of vital energy, promoting blood circulation and stopping pain, expelling wind and removing dampness.For heart peratodynia, abdominal distention is vomited and diarrhoea, hemiplegia, limbs flaccidity syndrome and arthralgia syndrome, epersalgia cough.The < < detailed outline > > that picks up any lost article from the road carries: " promoting the circulation of blood divides, warming the spleen and stomach, and the five internal organs, and muscle reinforcing and bone strengthening, dries and searches wind, and tonifying YANG road, controls timidity.”
Herba veronicastri villosuli: bitter in the mouth, pungent, cool in nature, slightly poisonous; Return liver, lung, kidney channel.Inducing diuresis to remove edema, dissipating blood stasis removing toxic substances.For ascites edema, dysuria, menoxenia, traumatic injury, burn and scald, venom.The herbal > > in east, < < Fujian: " herb: restore menstrual flow and invigorate blood circulation, removing blood stasis to promote tissue regeneration, relaxing muscles and tendons detumescence.Control menoxenia, year gout of a specified duration, traumatic injury, edema tympanites.”
Radix Cinnamomi Camphorae: acrid in the mouth, warm in nature; Return liver, spleen channel.Vital energy regualting and blood circulation-promoting, except rheumatism.For vomiting and dirarrhea, trusted subordinate's distending pain, rheumatic arthralgia, traumatic injury, scabies pruritus.< < Hunan medicine will > > carries: " deliver, cold expelling, circulation of qi promoting, invigorates blood circulation, detumescence, pain relieving.”
Herba Psiloti Nudi: sweet in the mouth, pungent, slightly warm in nature; GUIXIN, liver, stomach warp.Promoting blood circulation to restore menstrual flow, wind-damp dispelling.For rheumatic arthralgia, women's amenorrhea, traumatic injury.< < Quanzhou book on Chinese herbal medicine > > carries: " promoting blood circulation to restore menstrual flow, by blood removing blood stasis with potent drugs, wind-damp dispelling, sharp joint.Control arthragra, regurgitation vomiting, married woman's amenorrhea.”
Rhizoma zingiberis miogae: acrid in the mouth, light, warm in nature, slightly poisonous.Promoting blood flow to regulate menstruation, relieving cough and expelling phlegm, subduing swelling and detoxicating.For menoxenia, old cough, the skin ulcer scrofula that swells, conjunctival congestion sore throat.< < Guizhou side's medicine among the people collection > > carries: " restore menstrual flow and invigorate blood circulation, again can relieving cough and expelling phlegm.External can be drawn out pus by applying a plaster to the affected part, and the skin ulcer that disappears is swollen.”
Herba Lamii Amplexicaulis: bitter in the mouth, pungent, property is flat.Clearing away heat-damp and promoting diuresis, promoting blood circulation by removing wind, subduing swelling and detoxicating.For hypertension, facial paralysis, hemiplegia, traumatic pain, fracture, impetigo.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > > carries: " control muscles and bones phlegm-fire pain, numb hand and foot is meciless.The dispel wind of whole body migration, loose scrofula brothers sucutaneous nodule.Control traumatic injury, synthetism.Stop sinusitis with purulent discharge nasal sinusitis.Bag phlegm-fire congestion and swelling pain.”
Herba pogonatheri criniti: sweet in the mouth, light, cool in nature; Return spleen, kidney, urinary bladder channel.Heat clearing away, diuretic.For calentura excessive thirst, icterohepatitis, diabetes, drench erosion hematuria, dysuria.The conventional Chinese herbal medicine handbook > > of < < carries: " control urinary tract infection, nephritis, edema, the high heat of flu, icterohepatitis, diabetes.”
Herba cypripedii japonici: mildly bitter flavor, property is flat, poisonous; Return liver, lung, kidney channel.Vital energy regualting and blood circulation-promoting, preventing the attack (or recurrence) of malaria removing toxic substances.For impairment caused by overstrain lumbago, traumatic injury, rheumatic arthralgia, menoxenia, venom, skin pruritus.
Radix Saposhnikoviae: acrid in the mouth, sweet, warm in nature; Return bladder, liver, spleen channel.Deliver and dispel the wind, removing dampness to relieve pain.For affection of exogenous wind-cold, headache and dizziness, anemofrigid-damp arthralgia, joint is ached, and extremity contraction is anxious.< < Changsha medicine solution > > carries: " network of passing through, by wet excessive, gets round by bribery, and pain relieves the pain; relaxing muscles and tendons arteries and veins, stretches anxious contraction, and the podomere of living; play paralysis, hold back spontaneous perspiration, helmet antiperspirant breaks, metrorrhagia.”
Herba Potentillae Chinensis: bitter in the mouth, micro-peppery, cold in nature.Wind-damp dispelling, removing toxic substances.For dysentery, rheumatism bones and muscles pain, paralysis, epilepsy, skin ulcer scabies.< < Kweiyang medicinal herbs > among the people > carries: " heat-clearing and toxic substances removing.Control under dysentery with red and white feces rheumatalgia, paralysis.”
Rhizoma Arisaematis: bitter in the mouth, pungent, warm in nature, poisonous; Return liver, lung, spleen channel.Drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia.< < herbal classic > > carries: " main pained, cold and heat, stagnation of QI, gathers, fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times, muscle and tendon injury, flaccidity, arrests and delays, dredging water passages.”
Herba Pachysandrae Stylosae: acrid in the mouth, hardship, warm in nature, poisonous; Return spleen, kidney channel.Expelling wind and removing dampness, promoting blood circulation and stopping pain.For rheumatic arthralgia, numb limbs and tense tendons, impairment caused by overstrain lumbago, traumatic injury, headache.< < Guizhou medical herbs > > carries: " invigorate blood circulation, blood stasis dispelling, pain relieving.”
Semen Sinapis: acrid in the mouth, hot in nature, poisonous; Return lung meridian.Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison.For cold syndrome of the stomach, tell food, trusted subordinate's pain, lung cold cough, arthralgia aggravated by cold sore throat, traumatic injury.< < detailed outline > > carries: " warming spleen and stomach for dispelling cold, eliminating phlegm profit key.Control cold syndrome of the stomach and tell food, lung cold cough, air-cooled pain due to disorder of QI, locked mouth lockjaw.Dissipation carbuncle, blood stasis.”
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine theoretical, the effect with expelling wind and removing dampness, vital energy regualting and blood circulation-promoting, dissipating blood stasis for subsidence of swelling, hepatic cholagogic, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, to cerebral thrombosis, thrombosis expansion has fabulous alleviation and therapeutic effect, is suitable for cerebral thrombosis clinical treatment and nursing and applies.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Benzoinum 88g Fructus Rhododendri Mollis 85g Herba chloranthi japonici 83g Martianus dermestoides Chevr. 81g
Herba veronicastri villosuli 88g Radix Cinnamomi Camphorae 73g Herba Psiloti Nudi 70g Rhizoma zingiberis miogae 68g
Herba Lamii Amplexicaulis 66g Herba pogonatheri criniti 63g Herba cypripedii japonici 61g Radix Saposhnikoviae 59g
Herba Potentillae Chinensis 58g Rhizoma Arisaematis 54g Herba Pachysandrae Stylosae 53g Semen Sinapis 48g.
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) get Benzoinum, Herba chloranthi japonici, Herba cypripedii japonici and Rhizoma Arisaematis and remove impurity, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) after Fructus Rhododendri Mollis, Herba veronicastri villosuli, Herba pogonatheri criniti and Herba Potentillae Chinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, standby;
(3) Martianus dermestoides Chevr., Radix Cinnamomi Camphorae, Herba Psiloti Nudi and Semen Sinapis are put in container, added the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.13, dry, standby;
(4) Qu Rhizoma zingiberis miogae, Herba Lamii Amplexicaulis, Radix Saposhnikoviae and Herba Pachysandrae Stylosae are mixed thoroughly vexed with saline, with the micro-stir-fry of little fire, taking-up is dried, and are placed in mortar and grind into powder, cross 200 order fine powders, standby;
(5) thick paste of the fine powder of step (1), step (2), step (4) gained and step (3) gained is made to capsule, be the Chinese medicine preparation for the treatment of cerebral thrombosis of the present invention.
Usage and dosage: oral, each 3, every day 3 times, the morning, noon and afternoon each once, warm water delivery service in a hour after meal, 15 days is a course for the treatment of, common 3～4 courses for the treatment of are effective, pertinacious disease needs 5～6 courses for the treatment of.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Benzoinum 81g Fructus Rhododendri Mollis 78g Herba chloranthi japonici 76g Martianus dermestoides Chevr. 74g
Herba veronicastri villosuli 71g Radix Cinnamomi Camphorae 66g Herba Psiloti Nudi 64g Rhizoma zingiberis miogae 61g
Herba Lamii Amplexicaulis 60g Herba pogonatheri criniti 56g Herba cypripedii japonici 54g Radix Saposhnikoviae 52g
Herba Potentillae Chinensis 51g Rhizoma Arisaematis 47g Herba Pachysandrae Stylosae 46g Semen Sinapis 41g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Benzoinum 74g Fructus Rhododendri Mollis 71g Herba chloranthi japonici 69g Martianus dermestoides Chevr. 67g
Herba veronicastri villosuli 64g Radix Cinnamomi Camphorae 59g Herba Psiloti Nudi 57g Rhizoma zingiberis miogae 54g
Herba Lamii Amplexicaulis 53g Herba pogonatheri criniti 49g Herba cypripedii japonici 47g Radix Saposhnikoviae 45g
Herba Potentillae Chinensis 44g Rhizoma Arisaematis 40g Herba Pachysandrae Stylosae 39g Semen Sinapis 34g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Benzoinum 67g Fructus Rhododendri Mollis 63g Herba chloranthi japonici 62g Martianus dermestoides Chevr. 60g
Herba veronicastri villosuli 57g Radix Cinnamomi Camphorae 52g Herba Psiloti Nudi 49g Rhizoma zingiberis miogae 47g
Herba Lamii Amplexicaulis 43g Herba pogonatheri criniti 42g Herba cypripedii japonici 41g Radix Saposhnikoviae 38g
Herba Potentillae Chinensis 37g Rhizoma Arisaematis 32g Herba Pachysandrae Stylosae 32g Semen Sinapis 27g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
The routine clinical observation of cerebral thrombus patient 400 of selecting Wo Yuanhuo outer court to make a definite diagnosis, patient is divided into two groups at random, treatment group 200 examples, male's 100 examples wherein, women's 100 examples, 28～78 years old age, 48.3 years old mean age, the course of disease 5 months～20 years, average 8 years; Matched group 200 examples, male's 102 examples wherein, women's 98 examples, 30～75 years old age, 43 years old mean age, the course of disease 6 months～23 years, average 7 years.
The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, usage and dosage: oral, each 3, every day 3 times, the morning, noon and afternoon each once, warm water delivery service in a hour after meal, 15 days is a course for the treatment of, common 3～4 courses for the treatment of are effective, pertinacious disease needs 5～6 courses for the treatment of.
Matched group is taken breviscapus pulse-engendering capsule, oral, one time 2,3 times on the one, within 30 minutes after meal, take.Within two months, be a course for the treatment of, the course for the treatment of can be continuous.Consolidate curative effect or prevention of recurrence, one time 1,3 times on the one.
3, efficacy determination:
(1) cure: traction property headache, eye are opened the transference cures such as stupor, vascular occlusion, numb limbs and tense tendons; Clearheaded, activity freely.
(2) effective: above-mentioned symptom is alleviated to some extent, clearheaded, and activity freely.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 145 examples, effective 45 examples, invalid 10 examples, cure rate 72.5%, total effective rate 95%.
In matched group, cure 70 examples, effective 80 examples, invalid 50 examples, cure rate 35%, total effective rate 75%.
Above result demonstration, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is given an example:
1, money * *, man, 72 years old, peasant, people from changzhou.Originally there is numb hand and foot, kraftlos symptom in patient, follows of short duration losing the sight of both eyes, parathria, after just recover very soon normal.Later stage falls in a swoon suddenly on ground, and eye is opened stupor.To our hospital, be diagnosed as cerebral thrombosis.Take Chinese medicine preparation of the present invention after 3 courses for the treatment of, numb limbs and tense tendons, the transference cure such as have a dizzy spell, laboratory indexes is all normal.Follow up a case by regular visits to not recurrence so far.
2, grandson * *, female, 60 years old, retired worker, people from Handan, Hebei.Patient takes a walk in way, and prominent sense is dizzy, bitterly, right side weakness of the lower extremities then, the towing of walking, in right upper extremity sense, lift unable, roadside have a rest in upper right weakness of the lower extremities continue to increase the weight of.Medical by my institute, find brain in patients supply imbalance, intractable singultus, is diagnosed as cerebral thrombosis.Take Chinese medicine preparation of the present invention, take after 2 courses for the treatment of, health is rehabilitation gradually, and no headache, the symptom such as dizzy are obviously alleviated, and continue to take 3 courses for the treatment of, above transference cure.Follow up a case by regular visits to not recurrence so far.
3, Lee * *, female, 54 years old, private owner, Tonghua, Jilin Province people.How the symptoms such as numb limbs and tense tendons once appearred in patient, unable, fall ill in nighttime sleep, and wake up morning next day and just find half body quadriplegia, and with disturbance of consciousness in various degree.Bei Wo institute is diagnosed as cerebral thrombosis.Take Chinese medicine preparation of the present invention after 2 courses for the treatment of, symptom takes a turn for the better, continue to take after 3 courses for the treatment of, and transference cure, activity freely, is not recurred.
4, week * *, man, 46 years old, sales manager, people from Jiamusi, Heilungkiang.Patient starts to occur the symptoms such as aphasia, lower limb hemiplegia, stupor without obvious inducement, rear to our hospital, and the arterial blood tube wall generation pathologic that discovery patient intracranial is supplied brain outward changes, slow blood flow, and blood viscosity increases.Bei Wo institute is diagnosed as cerebral thrombosis.Take Chinese medicine preparation of the present invention after 4 courses for the treatment of, symptom disappears completely, clearheaded, and activity freely, livelihood restoration is normal.
5, Wu * *, female, 40 years old, university teacher, people from Yingkou, Liaoning.Patient suffers from arteriosclerosis, diabetes disease, occurs in the recent period the symptoms such as hemidysesthesia, hemianopsia, is diagnosed as cerebral thrombosis, once takes various hormones, analgesic etc., and effect is all not obvious, lethargy.Taking Chinese medicine preparation of the present invention after 3 courses for the treatment of, symptom takes a turn for the better, continue to take after 2 courses for the treatment of, and transference cure, activity freely, is not recurred.
6, Zheng * *, man, 38 years old, builder, people from Siping., there is dizzy, nystagmus in patient's oblongata back of the body lateral part infraction, the symptoms such as glossopharyngeum, vagus nerve paralysis, and Bei Wo institute is diagnosed as cerebral thrombosis.Take Chinese medicine preparation of the present invention after 3 courses for the treatment of, symptom obviously alleviates, and then takes after 2 courses for the treatment of, and physical recovery is normal, and activity freely.Follow up a case by regular visits to not recurrence so far.
Claims (5)
1. a Chinese medicine preparation for the treatment of cerebral thrombosis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
52～82 parts of 54～84 parts of Martianus dermestoides Chevr. of 56～86 parts of Herba chloranthi japonicis of 59～89 parts of Fructus Rhododendri Molliss of Benzoinum
39～69 parts of 44～74 parts of Herba Psiloti Nudis of 49～79 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 41～71 Fen Rhizoma zingiberis miogae
30～60 parts of 32～62 parts of Radix Saposhnikoviaes of 34～64 parts of Herba cypripedii japonici of 37～67 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
19～49 parts, 24～54 parts of Semen Sinapiss of 25～55 parts of Herba Pachysandrae Stylosaes of 29～59 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
2. a Chinese medicine preparation for the treatment of cerebral thrombosis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
74 parts of 76 parts of Martianus dermestoides Chevr. of 78 parts of Herba chloranthi japonicis of 81 parts of Fructus Rhododendri Molliss of Benzoinum
61 parts of 66 parts of Herba Psiloti Nudis of 71 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 64 Fen Rhizoma zingiberis miogae
52 parts of 54 parts of Radix Saposhnikoviaes of 56 parts of Herba cypripedii japonici of 60 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
41 parts, 46 parts of Semen Sinapiss of 47 parts of Herba Pachysandrae Stylosaes of 51 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
3. a Chinese medicine preparation for the treatment of cerebral thrombosis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
67 parts of 69 parts of Martianus dermestoides Chevr. of 71 parts of Herba chloranthi japonicis of 74 parts of Fructus Rhododendri Molliss of Benzoinum
54 parts of 59 parts of Herba Psiloti Nudis of 64 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 57 Fen Rhizoma zingiberis miogae
45 parts of 47 parts of Radix Saposhnikoviaes of 49 parts of Herba cypripedii japonici of 53 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
34 parts, 39 parts of Semen Sinapiss of 40 parts of Herba Pachysandrae Stylosaes of 44 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
4. a Chinese medicine preparation for the treatment of cerebral thrombosis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
60 parts of 62 parts of Martianus dermestoides Chevr. of 63 parts of Herba chloranthi japonicis of 67 parts of Fructus Rhododendri Molliss of Benzoinum
47 parts of 52 parts of Herba Psiloti Nudis of 57 parts of Radix Cinnamomi Camphoraes of Herba veronicastri villosuli, 49 Fen Rhizoma zingiberis miogae
38 parts of 41 parts of Radix Saposhnikoviaes of 42 parts of Herba cypripedii japonici of 43 parts of Herba pogonatheri crinitis of Herba Lamii Amplexicaulis
27 parts, 32 parts of Semen Sinapiss of 32 parts of Herba Pachysandrae Stylosaes of 37 parts of Rhizoma Arisaematiss of Herba Potentillae Chinensis.
5. a preparation method for the Chinese medicine preparation of the treatment cerebral thrombosis as described in claim 1～4, is characterized in that: comprise following processing step:
(1) get Benzoinum, Herba chloranthi japonici, Herba cypripedii japonici and Rhizoma Arisaematis and remove impurity, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) after Fructus Rhododendri Mollis, Herba veronicastri villosuli, Herba pogonatheri criniti and Herba Potentillae Chinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, standby;
(3) Martianus dermestoides Chevr., Radix Cinnamomi Camphorae, Herba Psiloti Nudi and Semen Sinapis are put in container, added the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.13, dry, standby;
(4) Qu Rhizoma zingiberis miogae, Herba Lamii Amplexicaulis, Radix Saposhnikoviae and Herba Pachysandrae Stylosae are mixed thoroughly vexed with saline, with the micro-stir-fry of little fire, taking-up is dried, and are placed in mortar and grind into powder, cross 200 order fine powders, standby;
(5) thick paste of the fine powder of step (1), step (2), step (4) gained and step (3) gained is made to capsule, be the Chinese medicine preparation for the treatment of cerebral thrombosis of the present invention.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6330415A (en) * | 1986-07-23 | 1988-02-09 | Tsumura Juntendo Inc | Antioxidation agent |
| CN101972375A (en) * | 2010-10-29 | 2011-02-16 | 许子建 | Soup for treating hemiplegia and strengthening body resistance |
-
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6330415A (en) * | 1986-07-23 | 1988-02-09 | Tsumura Juntendo Inc | Antioxidation agent |
| CN101972375A (en) * | 2010-10-29 | 2011-02-16 | 许子建 | Soup for treating hemiplegia and strengthening body resistance |
Non-Patent Citations (3)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典：2010年版一部》", 31 January 2010 * |
| 夏丽英等: "《现代中药毒理学》", 31 October 2005 * |
| 江西药科学校革命委员会: "《草药手册》", 31 January 1970 * |
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Effective date of registration: 20151216 Address after: 601, room 1, unit 3, building 35, geological and mineral home, No. 276826, Haibin five road, Donggang District, Shandong, Rizhao City Applicant after: Sun Tingting Address before: The holy city of Shandong province Weifang city 262700 Street No. 98, Shouguang City, Shouguang City Hospital of traditional Chinese Medicine Applicant before: Ren Hongmei |
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