CN103977261B - A kind of treat Chinese medicine composition of freckle and preparation method thereof - Google Patents
A kind of treat Chinese medicine composition of freckle and preparation method thereof Download PDFInfo
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- CN103977261B CN103977261B CN201410246166.1A CN201410246166A CN103977261B CN 103977261 B CN103977261 B CN 103977261B CN 201410246166 A CN201410246166 A CN 201410246166A CN 103977261 B CN103977261 B CN 103977261B
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Abstract
A kind of treat Chinese medicine composition of freckle and preparation method thereof, by following each raw materials, weigh by weight：8 12 parts of Squama Maniss, 59 parts of Flos persicae, 8 12 parts of Radix Ginseng, 13 17 parts of % of the Radix Astragali, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae 3-7 part, Serissa foetida 3-7 part, above-mentioned spice is pulverized to load in mixture adds the ethanol of 1.5 times of its gross mass to cover tightly in container, after soaking 72 hours, filter out medicinal liquid, again plus 34 times of Chinese medicine weight plasma water in container, fry 10 30 minutes by slow fire, it is cooled to room temperature, filter, to filtrate mix homogeneously twice, addition Carbomer is fully swelling both to have obtained finished product, the present invention treats the Chinese medicine composition of freckle, to treatment freckle, there is good therapeutic efficiency, using pure Chinese medicinal preparation, Small side effects, low cost.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly to a kind of Chinese medicine composition treating freckle and its preparation side
Method..
Background technology
Freckle is a kind of light brown fleck, and freckle, in addition to heredity, also can lead to because passages through which vital energy circulates is obstructed stop in congestion,
Retardance is not smooth, and painstaking effort can not reach skin face, nutrition skin, and the metabolism rubbish in skin, nuisance and melanin are just not
Can discharge with the eubolism of human body, gradually deposition is the formation of freckle.Increase the cheese in dermal melanin cell
Propylhomoserin enzymatic activity, under ultraviolet irradiation, generates a large amount of melanin, also can form freckle.Freckle often comes across forehead, the bridge of the nose
With cheek etc., also occur in cervical region, shoulder, the back of the hand etc. once in a while, hinder beauty treatment.Using Therapeutic Method high cost, effect
Really undesirable.
Content of the invention
The technical problem to be solved is：There is provided a kind of Chinese medicine composition treating freckle, by selecting to close
Suitable compound ratio, reaches the good purpose of Small side effects, low cost, therapeutic effect.
Technical scheme is as follows：
A kind of treat Chinese medicine composition of freckle and preparation method thereof it is characterised in that：Each former by following portions by weight
Material medicine is made：8 12 parts of Squama Maniss, 59 parts of Flos persicae, 8 12 parts of Radix Ginseng, 13 17 parts of % of the Radix Astragali, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis
15 parts, Folium Vaccinii vitis-idaeae 3-7 part, Serissa foetida 3-7 part, Carbomer 1-3 part, deionized water 35-45 part.
The preferred weight number of described each crude drug is：9 11 parts of Squama Maniss, 68 parts of Flos persicae, 9 11 parts of Radix Ginseng, Huang
14 16 parts of % of stilbene, 24 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 24 parts of Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae 4-6 part, Serissa foetida 4-6 part, 2 parts of Carbomer, deionized water
38-42 part.
The parts by weight of described each crude drug are most preferably elected as：10 parts of Squama Maniss, 7 parts of Flos persicae, 10 parts of Radix Ginseng, 15 parts of the Radix Astragali,
3 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Radix Angelicae Sinensis, 5 parts of Folium Vaccinii vitis-idaeae, 5 parts of Serissa foetida, 2 parts of Carbomer, 40 parts of deionized water.
Described a kind of treat Chinese medicine composition of freckle and preparation method thereof, its preparation technology is as follows：
Step one, sorting, by Squama Maniss, Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida Chinese medicine in mass ratio
Weigh.
Step 2, it is pulverized and mixed, each spice of above-mentioned steps is carried out mixing, pulverizes and load in mixture in container；Plus ethanol lid
Tightly.
Step 3, immersion, the crushed mixture spice in above-mentioned steps is added ethanol rear enclosed to carry out soaking, filter.
Step 4, each spice in above-mentioned steps two is loaded in mixture in container plus plasma water is in container, slow fire is fried
10 30 minutes, it is subsequently cooled to room temperature, filter.
Step 5, will after the medicinal liquid mix homogeneously that filter twice in step 3 and step 4 add Carbomer fully swelling both
Obtain finished product.
Described a kind of treat Chinese medicine composition of freckle and preparation method thereof it is characterised in that：Add in described step 3
The amount of ethanol is 1.5 times of Chinese medicine quality；Described soak time is 72 hours.
Described a kind of treat Chinese medicine composition of freckle and preparation method thereof, add plasma water in described step 4
Quality is 34 times of Chinese medicine spice.
The present invention treats the Chinese medicine composition of freckle, has good therapeutic efficiency to treatment freckle, using pure Chinese medicine system
Agent, Small side effects, low cost.Over one hundred example, effective percentage is used in Nanyang and Puyang each city-level the People's Hospital between 2010 to 2013 years
Big more than 90%.
The pharmacological effect of each crude drug of the present invention is as follows：
Squama Maniss：For the scale of Manidae animal Squama Maniss, be good at walking to alter, open blood stasis, open blood gather, have the work(such as promoting blood circulation to remove obstruction in the collateral
Energy.
Flos persicae：There is sterilizing and itch-relieving, blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, dispelling wind for relieving itching, skin ulcer of dispelling brighten, Glycerin.Improve blood
Liquid circulates, and promotes skin-nourishing and oxygen supply, makes the lipofuscin element of promotion human senility accelerate excretion, prevents melanin in skin
Interior chronic deposition, reaches whitening effect.
Radix Ginseng：Nourish skin, skin moistening wrinkle removing, Whitening, spot, make skin smooth flexible.
The Radix Astragali：The Radix Astragali can dramatically increase the total white blood cellses in blood, promotes the phagocytosis of neutrophilic granulocyte and macrophage
Function and sterilizing ability, it has enhancing human body immunity function, the Radix Astragali to have：Dispelling speckles and whitening face suppresses face pigmentation.
The Pseudobulbus Bletillae (Rhizoma Bletillae)：The Pseudobulbus Bletillae (Rhizoma Bletillae) has whitening and speckle dispelling, astringing to arrest bleeding, detumescence and promoting granulation.And the skins such as acne, tinea corporis, cicatrix can be treated
Skin disease.Contain the compositions such as abundant starch, volatile oil and phlegmatic temperament in the Pseudobulbus Bletillae (Rhizoma Bletillae), the vestige that acne stays on the face can be eliminated, and can
Moist, skin whitening, makes skin as smooth as jade.
Radix Angelicae Sinensis：Abundant vitamin A, vitamin B12, Vitamin E, cobalamine, volatile oil and human body is contained in Radix Angelicae Sinensis powder
Required 17 kinds of aminoacid, including 7 kinds of aminoacid that are needed by human but can not synthesizing；Contain 23 kinds of inorganic elementss, wherein simultaneously
16 kinds is necessary to human body, such as calcium, copper, zinc, phosphorus, potassium, ferrum etc..Radix Angelicae Sinensis are anti-ageing, speckle removing, beauty treatment, effect of skin and complexion improving.
Folium Vaccinii vitis-idaeae：Arbutin passes through the activity that suppression produces melanic ferment Tyrosinase, reduces melanic generation, it
Skin can be rapidly permeated into, while not affecting skin cell proliferation concentration, effectively suppress the work of tryrosinase in skin
Property, blocking melanic formation, by itself combination with tryrosinase, accelerating melanic decomposition and excretion, thus reducing
Skin pigmentation, dispelling stain and freckle.
Serissa foetida：Dispelling wind to relieve the exterior syndrome, clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral.Skin of face blood circulation can effectively be accelerated, promote newly old
Metabolism, suppresses melanin, regenerative cell is moistened in nutrition, thus reaching whitening and speckle dispelling, the effect of skin care skin care.
Carbomer：Carbomer (conventional amount used 0.25-0.5%) under very low consumption just can produce efficient thickening power,
Thus preparing the very emulsion of wide range of viscosities and different rheological characteristic, cream, gel and preparation capable of permeating skin
Deionized water：There are calcium ions and magnesium ions in water, easily formed and precipitate with Organic substance, deionized water is exactly pure water.Specifically
Embodiment
Below in conjunction with specific embodiment, technical scheme is further detailed, but the guarantor of the present invention
Shield scope is not limited thereto：
Embodiment 1
Weigh by weight：10 parts of Squama Maniss, 7 parts of Flos persicae, 10 parts of Radix Ginseng, 15 parts of the Radix Astragali, 3 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Radix Angelicae Sinensis, Bearss
Really 5 parts, 5 parts of Serissa foetida, 2 parts of Carbomer, 40 parts of deionized water.
First, the Squama Maniss in above-mentioned spice, Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida are pulverized and mixed
It is contained in container, plus the ethanol of 1.5 times of Chinese medicine quality covers tightly, after soaking 72 hours, filter out medicinal liquid；Secondly, then by Squama Maniss,
Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida pulverize after respectively to expect add the plasma water of 3 times of its gross weight in
In container, fry by slow fire 10 minutes, be cooled to room temperature, filter；Finally, will filtrate mix homogeneously twice, add Carbomer fully molten
Swollen both finished product.
Instructions of taking：The finished product obtaining medicament is applied in affected part.
Embodiment 2：
Weigh by weight：12 parts of Squama Maniss, 9 parts of Flos persicae, 12 parts of Radix Ginseng, 17 parts of the Radix Astragali, 5 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 4 parts of Radix Angelicae Sinensis, Bearss
Really 5 parts, 5 parts of Serissa foetida, 3 parts of Carbomer, 45 parts of deionized water.
First, the Squama Maniss in above-mentioned spice, Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida are pulverized and mixed
It is contained in container, plus the ethanol of 1.5 times of Chinese medicine quality covers tightly, after soaking 72 hours, filter out medicinal liquid；Secondly, then by Squama Maniss,
Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida pulverize after respectively to expect add the plasma water of 4 times of its gross weight in
In container, fry by slow fire 30 minutes, be cooled to room temperature, filter；Finally, will filtrate mix homogeneously twice, add Carbomer fully molten
Swollen both finished product.
Instructions of taking：The finished product obtaining medicament is applied in affected part.
Embodiment 3：
Weigh by weight：8 parts of Squama Maniss, 5 parts of Flos persicae, 8 parts of Radix Ginseng, 13 parts of the Radix Astragali, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae 3
Part, 3 parts of Serissa foetida, 1 part of Carbomer, 35 parts of deionized water.
First, the Squama Maniss in above-mentioned spice, Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida are pulverized and mixed
It is contained in container, plus the ethanol of 1.5 times of Chinese medicine quality covers tightly, after soaking 72 hours, filter out medicinal liquid；Secondly, then by Squama Maniss,
Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida pulverize after respectively to expect add the plasma water of 3.5 times of its gross weight
In container, fry by slow fire 20 minutes, be cooled to room temperature, filter；Finally, will filtrate mix homogeneously twice, add Carbomer abundant
Swelling both finished product.
Instructions of taking：The finished product obtaining medicament is applied in affected part.
Curative effect judging standard：
1. cure：Diagnostic criteria recovers normal.Symptom all disappears, and freckle is wholly absent；
2. effective：Clinical symptoms disappear substantially, and freckle still could not be wholly absent.
3. effective：Clinical fundamental symptomss mitigate, and main freckle significantly reduces.
4. invalid：Before and after treatment, result is unchanged.
Table 1 all ages and classes clinical data counts
| Age | Case load（Number） | Cure | Significantly | Effectively | Invalid |
| 40-50 | 20 | 11 | 5 | 4 | 0 |
| 50-55 | 40 | 23 | 10 | 7 | 0 |
| 55-60 | 15 | 5 | 2 | 4 | 4 |
| Effective percentage | 52% | 22.7% | 20% | 5.3% |
From above clinical data, the advantage of medicine of the present invention be can treating both the principal and secondary aspects of a disease, can alleviate faster and cure
The pain disease that wind-cold damp pathogen causes.Easy to use, toxic and side effects are little.No pain is economical and practical, can warming the meridian relieve the pain, promoting blood circulationization
The stasis of blood, dredging the meridian, and energy expelling wind and removing dampness, improve microcirculation, the effect of especially severe are become apparent from.
Case one：
Zhang：Female, 23 years old, Changge City people from South Street, preschool teacher's school.My facial freckle, about in mid-March, 2006
The laser therapy of this city beauty parlor, rebound out freckle for 1 year about again., at inventor, to meet it on October 3rd, 2008
All there is freckle at the positions such as portion, forehead, eyelid, eye pouch, the bridge of the nose, cheek, upperlip.In here after one week treatment decrustation,
Begin to use here Chinese medicine formula to switch within one week normally, after two weeks, the colour of skin is ruddy glossy, terminate after three months, more closely
Through multiple call-on back by phone in several years, no rebound so far.
Case two：
Connect so-and-so：Female, 21 years old, Yuzhou City Dong Shili people from village, my facial freckle in August in 2009 15 days about, in Zheng
State cosmetic surgery hospital is treated with glory, does within 15 days 1 time, even does 6 times.Spot colors do not mitigate, and ungodliness does again.In 2009
November 6 came at inventor, saw that all there is freckle at the positions such as its face, forehead, eyelid, eye pouch, the bridge of the nose, cheek, upperlip.Through controlling
After treating one week decrustation, here Chinese medicine formula is begun to use to switch within one week normally, after two weeks, the colour of skin is ruddy glossy,
Terminate after three months, the more multiple call-on back by phone of interior warp in recent years, no rebound so far.
Case three：
Zhao so-and-so：Man, 23 years old, Luohe City dragon people from cities and towns, facial freckle in person, in mid-May, 2010 in Luohe City
Hospital dermatology department, using Therapeutic Method of fulgerizing, recurred freckle less than 1 year after treatment again.Carry out inventor in August in 2011 within 22nd
Place.See that all there is freckle at the positions such as its face, forehead, eyelid, eye pouch, the bridge of the nose, cheek, upperlip.Through one week treatment decrustation
Afterwards, begin to use here Chinese medicine formula to switch within one week normally, after two weeks, the colour of skin is ruddy glossy, terminate after three months, then
Closely in two years through multiple call-on back by phone, no rebound so far.
Case four：
Lee so-and-so：Man, 24 years old, the Taikang County Yang Miao township Li great village administrative village Li great village 2, facial freckle in person, in 2009
On March 18, in does grinding in Taikang County hospital and changes skin art, controls the freckle that again rebounds out latter 2 years, to send out within 20th in September in 2011
At a person of good sense.See that all there is freckle at the positions such as its face, forehead, eyelid, eye pouch, the bridge of the nose, cheek, upperlip.Through one week treatment crust
After coming off, begin to use here Chinese medicine formula to switch within one week normally, after two weeks, the colour of skin is ruddy glossy, tie after three months
Bundle, more at no distant date through multiple call-on back by phone, no rebound so far.
Claims (6)
1. a kind of Chinese medicine composition treating freckle it is characterised in that：It is made up of each crude drug of following portions by weight：Squama Maniss
8 12 parts, 59 parts of Flos persicae, 8 12 parts of Radix Ginseng, 13 17 parts of the Radix Astragali, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae 3-7
Part, Serissa foetida 3-7 part, Carbomer 1-3 part, deionized water 35-45 part.
2. a kind of Chinese medicine composition treating freckle according to claim 1 it is characterised in that：Described each crude drug
Parts by weight are：9 11 parts of Squama Maniss, 68 parts of Flos persicae, 9 11 parts of Radix Ginseng, 14 16 parts of the Radix Astragali, 24 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), when
Return 24 parts, Folium Vaccinii vitis-idaeae 4-6 part, Serissa foetida 4-6 part, 2 parts of Carbomer, deionized water 38-42 part.
3. a kind of Chinese medicine composition treating freckle according to claim 1 it is characterised in that：Described each crude drug
Parts by weight are：10 parts of Squama Maniss, 7 parts of Flos persicae, 10 parts of Radix Ginseng, 15 parts of the Radix Astragali, 3 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Radix Angelicae Sinensis, 5 parts of Folium Vaccinii vitis-idaeae, June
5 parts of snow, 2 parts of Carbomer, 40 parts of deionized water.
4. a kind of preparation method of the Chinese medicine composition for the treatment of freckle as claimed in claim 1 is it is characterised in that it prepares work
Skill is as follows：Step one, sorting, by Squama Maniss, Flos persicae, Radix Ginseng, the Radix Astragali, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Angelicae Sinensis, Folium Vaccinii vitis-idaeae, Serissa foetida Chinese medicine in mass ratio
Weigh, step 2, be pulverized and mixed, each spice in above-mentioned steps one is carried out mixing, pulverizes and load in mixture in container, step 3,
Soak, the crushed mixture spice in above-mentioned steps two is added ethanol rear enclosed to carry out soaking, filter, step 4, will be above-mentioned
Each spice in step 3 loads in mixture in container plus deionized water is in container, fried 10 30 minutes of slow fire, then cools down
To room temperature, filter, step 5, Carbomer will be added after the medicinal liquid mix homogeneously filtering twice in step 3 and step 4 fully molten
Swollen both finished product, step 6, bag distribution packaging.
5. according to claim 4 treatment freckle Chinese medicine composition preparation method it is characterised in that：Described step 3
The amount of middle addition ethanol is 1.5 times of Chinese medicine quality；Described soak time is 72 hours.
6. the Chinese medicine composition for the treatment of freckle according to claim 4 preparation method it is characterised in that：Described step
In rapid four, the quality of addition deionized water is 34 times of Chinese medicine spice.
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| CN105902846A (en) * | 2016-04-23 | 2016-08-31 | 包晓娜 | Traditional Chinese medicinal composition for treating freckles |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0060092B1 (en) * | 1981-03-05 | 1985-07-03 | Sunstar Kabushiki Kaisha | Topical skin depigmenting composition |
| CN103816087A (en) * | 2014-03-05 | 2014-05-28 | 长春中医药大学 | Whitening, sun-resistant and spot removing cosmetic of traditional Chinese medicine composition, and preparation method thereof |
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2014
- 2014-06-05 CN CN201410246166.1A patent/CN103977261B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0060092B1 (en) * | 1981-03-05 | 1985-07-03 | Sunstar Kabushiki Kaisha | Topical skin depigmenting composition |
| CN103816087A (en) * | 2014-03-05 | 2014-05-28 | 长春中医药大学 | Whitening, sun-resistant and spot removing cosmetic of traditional Chinese medicine composition, and preparation method thereof |
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