CN103977197A - Traditional Chinese medicine solid preparation for treating anemopyretic cold - Google Patents
Traditional Chinese medicine solid preparation for treating anemopyretic cold Download PDFInfo
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- CN103977197A CN103977197A CN201410238425.6A CN201410238425A CN103977197A CN 103977197 A CN103977197 A CN 103977197A CN 201410238425 A CN201410238425 A CN 201410238425A CN 103977197 A CN103977197 A CN 103977197A
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Abstract
The invention discloses a traditional Chinese medicine solid preparation for treating an anemopyretic cold. The formula comprises the following raw materials in parts by weight: 10-20 parts of herba schizonepetae, 8-16 parts of chrysanthemum, 5-10 parts of mint, 5-10 parts of honeysuckle, 10-20 parts of water chestnut, 3-8 parts of gardenia, 6-12 parts of astragalus membranaceus, 3-8 parts of rhubarb, 5-10 parts of almond and 1-5 parts of liquorice. The traditional Chinese medicine solid preparation is used for treating an exogenous wind hot cold, is used for treating by adopting drugs for relaxing the bowels, and clearing heat and relieving exterior syndrome, and is significant in curative effect, strong in pertinence of pesticide effect, and free of toxic and side effects.
Description
Technical field
The present invention relates to a kind of solid preparation of Chinese medicine, be specifically related to a kind of solid preparation of Chinese medicine for the treatment of anemopyretic cold.
Background technology
Flu is common exterior syndromes of the four seasons, especially common when season alternation.The traditional Chinese medical science thinks that flu generally can be divided into anemofrigid cold and the large class of anemopyretic cold two, and these two kinds flu etiology and pathogenesis, symptom, Therapeutic Principle and medication difference are very large.Many families all have the Chinese patent medicine for the treatment of flu, after somebody catches a cold, have eaten many medicines, but disease do not alleviate, and key is there is no diagnosis and prescription.Anemopyretic cold is more common in summer and autumn, is due to evil criminal table, the lung qi of wind heat become estranged.Its symptom first showed as after constipation a couple of days, heating weight, micro evil wind, distending pain in the head, have that antiperspirant, red swelling and pain of throat, cough, expectorant are sticky or yellow, the yellow thick nasal discharge of having a stuffy nose, thirst and liking drink, the tip of the tongue limit are red, the micro-Huang of white and thin fur.At present, the medicine for the treatment of affection due to external wind and heat flu has a lot, and mostly adopting antipyretic, antiinflammatory is the Western medicine of leading, and side effect is larger, and drug dependence is strong, and therapeutic effect is limited, larger to actual bodily harm.And treatment by Chinese herbs is self to have the immunologic function of adjusting, to improve the advantages such as blood circulation, antipyretic-antalgic, antibacterial bacteriostatic, drug effect good absorbing have no side effect, win vast potential for future development.But natural drug or its compositionss such as traditional Chinese medicine, be often aided with other drug to treat, and the drug effect dependency between prescription is not strong, treat mainly with one-sided clearing away heat and expelling pathogen in the exterior medicine, medicine does not have tangible specific aim, and its onset is slow, curative effect is not good enough, and ordinary people is difficult to accept.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of solid preparation of Chinese medicine for the treatment of anemopyretic cold, this solid preparation of Chinese medicine, to treatment affection due to external wind and heat flu, adopts relieving constipation to coordinate clearing away heat and expelling pathogen in the exterior medicine to treat, evident in efficacy, drug effect essence is with strong points, has no side effect.
For solving the problems of the technologies described above, the present invention by the following technical solutions:
Treat a solid preparation of Chinese medicine for anemopyretic cold, comprise that following weight portion raw material makes: 10~20 parts of Herba Schizonepetae, 8~16 parts of Flos Chrysanthemis, 5~10 parts of Herba Menthaes, 5~10 parts of Flos Loniceraes, 10~20 parts of Corm Eleocharitiss, 3~8 parts of Flos Gardeniaes, 6~12 parts of the Radixs Astragali, 3~8 parts of Radix Et Rhizoma Rhei, 5~10 parts, Semen Armeniacae Amarum, 1~5 part, Radix Glycyrrhizae.
Preferably, parts by weight of raw materials is: 15 parts of Herba Schizonepetae, 12 parts of Flos Chrysanthemis, 8 parts of Herba Menthaes, 7 parts of Flos Loniceraes, 15 parts of Corm Eleocharitiss, 6 parts of Flos Gardeniaes, 9 parts of the Radixs Astragali, 5 parts of Radix Et Rhizoma Rhei, 8 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae.
Preferably, described solid preparation is clinical acceptance tablet, buccal tablet, capsule or granule.
The preparation method of the solid preparation of Chinese medicine for the treatment of anemopyretic cold of the present invention: take by weight the Chinese herbal medicine in prescription, decoct with water extraction of the juice 1~2 time, merge decoction liquor, add the ethanol of 70~80% concentration to leave standstill 1~2 day, filter, reclaim ethanol to the greatest extent, the clear liquid obtaining is concentrated, dry, and the powder cream of waiting until is made the solid preparation of accepting on medicine according to a conventional method.
Preferably, decoct temperature at every turn and be controlled at 85~95 DEG C, decocting time is 30~60 minutes.
Medicine of the present invention is suitable for crowd: affection due to external wind and heat common cold crowd all can use, but anemia of pregnant woman and 7 years old following child need use under doctor advised.
In each raw material of the present invention:
Herba Schizonepetae, taste is flat, warm in nature, nontoxic, and faint scent is dense, has the power of dispeling the wind strong, and effect that parch to black can hemostasis, commonly uses it in all headache due to invasion of exogenous pathogens diaphoresis, influenza, vomiting, treating measles and treating blood disorders side.Flos Chrysanthemi, sweet in the mouth, hardship, cold nature, the effect of there is wind-dispelling heat-dissipating, letting out clearly liver-heat, nourishing the liver to improve visual acuity, heat-clearing and toxic substances removing, cure mainly affection due to external wind and heat and epidemic febrile disease from the beginning of, companioned with headache person is especially suitable.Herba Menthae, acrid in the mouth, cool in nature, enters lung, Liver Channel, has dispelling wind and heat pathogens, the clear sharp head, effect of dermexanthesis poison thoroughly, is usually used in affection due to external wind and heat and epidemic febrile disease from the beginning of have exterior heat syndrome person, the headache of tap holder order, conjunctival congestion, laryngopharynx swelling and pain etc. in wind heat.Flos Lonicerae, sweet, micro-hardship, delicate fragrance, pungent, cold.Return lung,
stomach, the heart, large intestine channel, dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile diseases, as cards such as fever of the body, dermexanthesis, a speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.Corm Eleocharitis, sweet in the mouth is cold in nature, has clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, the diuresis relieving constipation effects such as de-swelling, conditioning hemorrhoid phlegm-heat cough, discomfort in the throat of eliminating the phlegm, help digestion, and is usually used in prophylaxis of acute infectious disease, measles, epidemic cerebrospinal meningitis.Flos Gardeniae, sweet-bitter flavor cold in nature, has pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body, cures mainly cough due to lung-heat, nose, coughs up phlegm, the diseases such as toxic swelling.The Radix Astragali, sweet in the mouth is warm in nature, has effect of invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.Radix Et Rhizoma Rhei, bitter in the mouth is cold in nature, stomach warp, large intestine channel, Liver Channel, spleen channel, there is heat and toxic materials clearing away, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling, let out damp and hotly to effect clearly, cure mainly excess-heat constipation, the accumulation of heat feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting, have blood in stool, hematuria, lump in the abdomen, pyretic toxicity carbuncle and ulcer, erysipelas etc.Semen Armeniacae Amarum, bitter in the mouth tepor, has the effect such as loosening bowel to relieve constipation, relieving cough and asthma, cures mainly the constipation that ailment said due to cold or exposure, dryness of the intestine cause, flu etc.Radix Glycyrrhizae, has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, timid phlegm and relieving cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, and, shortness of breath and palpitation weak for weakness of the spleen and stomach, tired state, cough with copious phlegm, the anxious pain of extremity contraction, cushion toxicity are strong etc.
The present invention treats the solid preparation of Chinese medicine of anemopyretic cold by scientific and reasonable synergism between relieving constipation, clearing away heat and expelling pathogen in the exterior Chinese medicine, can relieving constipation diuresis, heat-clearing and toxic substances removing, expelling pathogenic factors from muscles relieving the exterior syndrome, can evacuate again the merit of pathogenic factor in the exterior, the preparation making bring into play each drug effect length, can carry out treating both the principal and the secondary aspects of a disease at the same time from the source of disease of anemopyretic cold, clinical efficacy significantly, without drug dependence, have no side effect, cure rear nothing phenomenon repeatedly.
Detailed description of the invention
Be described further with specific embodiment below, but the present invention is not limited to these embodiment.
Embodiment 1
Treat a solid preparation of Chinese medicine for anemopyretic cold, its formula is: 15 parts of Herba Schizonepetae, 12 parts of Flos Chrysanthemis, 8 parts of Herba Menthaes, 7 parts of Flos Loniceraes, 15 parts of Corm Eleocharitiss, 6 parts of Flos Gardeniaes, 9 parts of the Radixs Astragali, 5 parts of Radix Et Rhizoma Rhei, 8 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae.
Take by weight the Chinese herbal medicine in prescription, add 6 times of decoctings at every turn and boil extraction of the juice 2 times, each temperature that decocts is controlled at 90 DEG C, each decocting time is 45 minutes, merges decoction liquor, adds the ethanol of 75% concentration to leave standstill 2 days, filter, reclaim ethanol to the greatest extent, the clear liquid obtaining is concentrated, dry, and the powder cream of waiting until is made the tablet of accepting on medicine according to a conventional method.
Embodiment 2
Treat a solid preparation of Chinese medicine for anemopyretic cold, its formula is: 20 parts of Herba Schizonepetae, 14 parts of Flos Chrysanthemis, 5 parts of Herba Menthaes, 10 parts of Flos Loniceraes, 16 parts of Corm Eleocharitiss, 3 parts of Flos Gardeniaes, 12 parts of the Radixs Astragali, 6 parts of Radix Et Rhizoma Rhei, 5 parts, Semen Armeniacae Amarum, 5 parts, Radix Glycyrrhizae.
Take by weight the Chinese herbal medicine in prescription, decoct with water extraction of the juice 2 times, merge decoction liquor, add the ethanol of 80% concentration to leave standstill 2 days, filter, reclaim ethanol to the greatest extent, the clear liquid obtaining is concentrated, dry, and the powder cream of waiting until is made the buccal tablet of accepting on medicine according to a conventional method.
Embodiment 3
Treat a solid preparation of Chinese medicine for anemopyretic cold, its formula is: 16 parts of Herba Schizonepetae, 8 parts of Flos Chrysanthemis, 10 parts of Herba Menthaes, 8 parts of Flos Loniceraes, 10 parts of Corm Eleocharitiss, 8 parts of Flos Gardeniaes, 10 parts of the Radixs Astragali, 3 parts of Radix Et Rhizoma Rhei, 10 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae.
Take by weight the Chinese herbal medicine in prescription, decoct with water extraction of the juice, add the ethanol of 70% concentration to leave standstill 1 day, filter, reclaim ethanol to the greatest extent, the clear liquid obtaining is concentrated, dry, and the powder cream of waiting until is made the capsule of accepting on medicine according to a conventional method.
Embodiment 4
Treat a solid preparation of Chinese medicine for anemopyretic cold, its formula is: 10 parts of Herba Schizonepetae, 16 parts of Flos Chrysanthemis, 7 parts of Herba Menthaes, 5 parts of Flos Loniceraes, 20 parts of Corm Eleocharitiss, 5 parts of Flos Gardeniaes, 6 parts of the Radixs Astragali, 8 parts of Radix Et Rhizoma Rhei, 7 parts, Semen Armeniacae Amarum, 1 part, Radix Glycyrrhizae.
Take by weight the Chinese herbal medicine in prescription, decoct with water extraction of the juice, add the ethanol of 75% concentration to leave standstill 1 day, filter, reclaim ethanol to the greatest extent, the clear liquid obtaining is concentrated, dry, and the powder cream of waiting until is made the granule of accepting on medicine according to a conventional method.
Clinical experiment example
Random choose anemopyretic cold patient of the present invention 400 people, are divided into 4 groups, and every group of 100 people, respectively organize symptom similar, take respectively the solid preparation that makes in embodiment 1~4 3 days.The evaluation criteria not disappearing according to healing, symptom disappearance completely, transference cure and symptom respectively, the medicinal liquid that each embodiment is made carries out Comprehensive Assessment.Its result is as following table:
? | Symptom does not disappear | Transference cure | Symptom disappears completely | Cure |
Embodiment 1 | 0 | 3 | 32 | 65 |
Embodiment 2 | 0 | 8 | 34 | 58 |
Embodiment 3 | 0 | 6 | 28 | 66 |
Embodiment 4 | 0 | 2 | 38 | 60 |
As can be seen from the above table, the medicinal liquid that current clinical trial does not have patient to make each embodiment is invalid, and complete layer chromatography >=92% of symptom, illustrates that the solid preparation that the present invention makes is evident in efficacy, is worthy to be popularized.
Claims (3)
1. treat the solid preparation of Chinese medicine of anemopyretic cold for one kind, it is characterized in that, comprise that following weight portion raw material makes: 10~20 parts of Herba Schizonepetae, 8~16 parts of Flos Chrysanthemis, 5~10 parts of Herba Menthaes, 5~10 parts of Flos Loniceraes, 10~20 parts of Corm Eleocharitiss, 3~8 parts of Flos Gardeniaes, 6~12 parts of the Radixs Astragali, 3~8 parts of Radix Et Rhizoma Rhei, 5~10 parts, Semen Armeniacae Amarum, 1~5 part, Radix Glycyrrhizae.
2. the solid preparation of Chinese medicine for the treatment of anemopyretic cold according to claim 1, it is characterized in that, comprise that following weight portion raw material makes: 15 parts of Herba Schizonepetae, 12 parts of Flos Chrysanthemis, 8 parts of Herba Menthaes, 7 parts of Flos Loniceraes, 15 parts of Corm Eleocharitiss, 6 parts of Flos Gardeniaes, 9 parts of the Radixs Astragali, 5 parts of Radix Et Rhizoma Rhei, 8 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae.
3. the solid preparation of Chinese medicine for the treatment of anemopyretic cold according to claim 1 and 2, is characterized in that: tablet, buccal tablet, capsule or granule that described solid preparation is clinical acceptance.
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CN104383332A (en) * | 2014-11-25 | 2015-03-04 | 华润三九(郴州)制药有限公司 | Compound Ganmaoling granules and preparation method thereof |
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CN102451356A (en) * | 2010-10-28 | 2012-05-16 | 罗朝雯 | Chinese medicinal herb cold tea |
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CN102451356A (en) * | 2010-10-28 | 2012-05-16 | 罗朝雯 | Chinese medicinal herb cold tea |
Cited By (1)
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CN104383332A (en) * | 2014-11-25 | 2015-03-04 | 华润三九(郴州)制药有限公司 | Compound Ganmaoling granules and preparation method thereof |
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Application publication date: 20140813 |