CN103977046A - Composition for promoting lead removal - Google Patents
Composition for promoting lead removal Download PDFInfo
- Publication number
- CN103977046A CN103977046A CN201410233741.4A CN201410233741A CN103977046A CN 103977046 A CN103977046 A CN 103977046A CN 201410233741 A CN201410233741 A CN 201410233741A CN 103977046 A CN103977046 A CN 103977046A
- Authority
- CN
- China
- Prior art keywords
- lead
- composition
- heme iron
- vitamin
- lead removal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a composition for promoting lead removal. The composition for promoting lead removal comprises ligusticum wallichii, L-zinc lactate, heme iron, active calcium and vitamin C. The composition disclosed by the invention can be used for promoting lead removal, relieving or preventing the damage to a human body caused by the lead, is free of toxic and side effects, fast in lead removal effect, applicable to being taken by people with high blood lead for a long period of time, and especially applicable to being taken by children, and has popularization and application value.
Description
[technical field]
The present invention relates to a kind of compositions that promotes Plumbum removing, belong to Chinese medicine composition technical field.
[background technology]
Lead is a kind of human body non-essential element, and ideal concentration plumbous in blood is zero.But along with the acceleration of urbanization and process of industrialization, Environmental Lead Exposure is on the rise, even have influence on the mankind's health.Lead in environment can enter human body by respiratory tract and skin, and with the formal distribution of phosphoric acid hydrogen lead in whole body, wherein have 90-95% to be converted into orthophosphate and be deposited in skeleton, tooth, internal organs, skin, hair, then transfer to lentamente in blood.The each tissue system of human body is all had to harm, wherein responsive to lead with nervous system and hemopoietic system.Be embodied in: affect growth and the skeleton development of intelligence, cause dyspepsia and endocrine disturbance, cause anemia, hypertension and arrhythmia, destroy renal function and immunologic function etc.In addition, lead also has carcinogenic effect.
According to international children ' s lead poisoning diagnostic criteria (blood lead value > 100ug/L), China's urban children lead poisoning prevalence rate is between 30%-40%, industrial pollution district, urban nearly 100%, even there is no the common urban district of obvious industrial pollution, also there is the children blood lead of 10%-30% to exceed standard.Plumbous to healthy potential hazard, day by day cause people's concern.
At present, preventing and treating saturnine basic principle is that environment intervention, health education and clinical treatment three combine, and environment intervention is basic, and health education is basic means, and more than alignment degree lead poisoning is just considered Drug therapy.The saturnine medicine of clinical treatment mainly contains calcium disodium chelate (CaNa2EDTA), sodium dimercaptosuccinate (DMSA) etc., though driving lead, these medicines can reduce lead load in body, Plumbum removing is effective, but can make micro elements needed by human run off, also can cause damage to kidney, side effect is larger, and drives nervous lesion that plumbous medicine causes lead and reverse and have little significance, so outside medicine Plumbum removing a good appetite suddenly appearing in a serious disease severe lead poisoning, clinically generally do not adopt.
Application number is that 97100452.8 patent of invention discloses one and drives plumbous Jiedu mixture, is to be prepared from by Fructus Lycii, Radix Astragali, Caulis Spatholobi, Semen Plantaginis, Folium Camelliae sinensis and Radix Glycyrrhizae; It is a kind of with raw materials such as Cordyceps that application number is that 201310169778.0 patent of invention discloses, the food health preserving tea electuary of the promotion Plumbum removing of making, the plumbous detoxicating functions of the oral rear-guard of above-mentioned patent of invention is certain, provides a kind of functional food easily and effectively for people's Antagonistic Environment pollutes.But taking tonification class Chinese medicine as main, as the Radix Astragali, Caulis Spatholobi, Cordyceps, be often not suitable for the pediatric population that lead content exceeds standard and take, and production cost is high in foregoing invention Chinese medicine composition.
[summary of the invention]
Drive the problems such as the toxic and side effects existing in plumbous medicine is large, production cost is high according to existing, the invention provides a kind of compositions that promotes Plumbum removing, there is cost low, effective, instant effect, the advantage that toxic and side effects is little.
For achieving the above object, the present invention is by the following technical solutions:
Promote a compositions for Plumbum removing, it is characterized in that percentage composition meter is composed of the following components by weight:
Rhizoma Chuanxiong 20%～50% Pfansteihl zinc 10%～30% heme iron 5%～20% activated calcium 10%～40% vitamin C 10%～30%
Wherein said heme iron and ascorbic part by weight are 1: 1.5～2.5
The compositions of above-mentioned promotion Plumbum removing is made up of following method:
(1) by above-mentioned weight proportion, often return water extraction process to extract Rhizoma Chuanxiong, make extractum, dry and pulverize, obtain extract fine powder;
(2) by above-mentioned weight proportion, Pfansteihl zinc, heme iron, activated calcium, vitamin C are mixed with above-mentioned (1) extract fine powder, stir.
The composition powder of promotion Plumbum removing of the present invention, can also pass through further common process, is prepared into routine and can takes medicine or edible functional food; The form of expression that can take medicine is oral liquid, capsule, tablet, electuary etc.; The form of expression of edible functional food is fruit jelly, confection, cookies cake, brew class beverage, directly drink class beverage etc.
Pharmacodynamic analysis of the present invention and being described as follows:
1: Rhizoma Chuanxiong has effect of benefiting QI and nourishing blood, blood-activating and qi-promoting, blood circulation promoting, accelerates discharge plumbous in health.
2:L-zinc lactate can provide zinc element, and plumbous and zinc has mutual antagonism, and when in body, lead tolerance is high, zinc content will decline, and zinc is the trace element that it is essential that human normal growth promoter is kept fit; Pfansteihl zinc has good bioavailability as zinc source, has obvious zinc supplement effect, can combine with the lead salt in body, makes it to excrete.
3: ferrum is the divalent metal element the same with lead with calcium, in small intestinal, belong to same delivery in conjunction with albumen, competitive each other, therefore plumbous high will zinc deficiency, iron deficiency, calcium deficiency, for reducing human body to plumbous absorption, should suitably increase the absorption of zinc, ferrum, calcium.Heme iron is good supplements-iron; Activated calcium is good calcium replenishing agent, can increase bone density, prevention of osteoporosis.
4: vitamin C excretes with feces in conjunction with generation is insoluble in the material of water with plumbous, and vitamin C can promote the absorption of ferrum simultaneously, lay special stress on heme iron and ascorbic ratio in the present invention, through practice, this ratio can significantly improve Plumbum removing effect.
Beneficial effect of the present invention:
1, do not contain tonification class Chinese medicine.Such as Cordyceps, the Radix Astragali etc., be applicable to adult and the children taking of various healths, be particularly suitable for children taking, long-term taking, has no side effect.
2, vitamin C has multiple action in the present invention, can excrete with feces in conjunction with generation is insoluble in the material of water with plumbous, can promote again the absorption of ferrum; Lay special stress on heme iron and ascorbic ratio in the present invention, through practice, in this ratio preparation, can significantly improve Plumbum removing effect and Plumbum removing speed.
3, in the present invention, each raw material is easy to get, and uses raw material type few, and production efficiency is high; Production cost is low simultaneously, and high low-income groups all can permanent consumption.
4, through practice, of the present invention have obvious reduction effect to blood lead, bone lead, liver lead and brain lead, has benefiting QI and nourishing blood simultaneously, effect of blood circulation promoting and blood stasis dispelling, have effective, the advantage of instant effect.
[detailed description of the invention]
Below in conjunction with specific embodiment, the invention will be further described:
Embodiment 1:
A kind of compositions that promotes Plumbum removing of the present invention, its by weight percentage composition comprise following component:
Rhizoma Chuanxiong 20% Pfansteihl zinc 20% heme iron 20% activated calcium 10% vitamin C 30%
The preparation of the present embodiment realizes by following steps:
(1) by above-mentioned weight proportion, often return water extraction process to extract Rhizoma Chuanxiong, make extractum, dry and pulverize, obtain extract fine powder;
(2) by above-mentioned weight proportion, Pfansteihl zinc, heme iron, activated calcium, vitamin C are mixed with above-mentioned (1) extract fine powder, stir.
By the powder obtaining, technique is made oral tablet routinely.
Embodiment 2:
A kind of compositions that promotes Plumbum removing of the present invention, its by weight percentage composition comprise following component:
Rhizoma Chuanxiong 43% Pfansteihl zinc 10% heme iron 5% activated calcium 30% vitamin C 12%
The preparation of the present embodiment realizes by following steps:
(1) by above-mentioned weight proportion, often return water extraction process to extract Rhizoma Chuanxiong, make extractum, dry and pulverize, obtain extract fine powder;
(2) by above-mentioned weight proportion, Pfansteihl zinc, heme iron, activated calcium, vitamin C are mixed with above-mentioned (1) extract fine powder, stir.
By the powder obtaining, technique granulation electuary routinely.
Evaluation of effect of the present invention
The present invention is higher as example taking blood lead, through 30 routine clinical observations.Selecting tcm diagnosis blood lead higher is standard: there is close Effects of Lead Exposure history, have the symptoms such as weak, abdominal part dull pain, abdominal distention, constipation, and blood lead >=100 μ g/L, lead in urine >=70 μ g/L.As above symptom, can make a definite diagnosis.In the object of making a definite diagnosis observation, male's 18 examples, women's 12 examples, without other serious disease, the age is 8～56 years old, the mean age is 28.5 years old.
Efficacy determination:
1, effective: weak disappearance, with it energetically; Abdominal pain and distension is significantly alleviated; Constipation disappears, free movement of the bowels; Blood lead content declines more than 10%, and lead in urine output increases more than 30%.
2, effective: weak, abdominal part dull pain, abdominal distention, constipation have clear improvement; Blood lead declines to some extent, and lead in urine output increases to some extent.
3, invalid: symptom is unchanged.
When clinical trial, withdraw other medicines and nutrient and healthcare products, take the oral tablet of the promotion Plumbum removing that the specific embodiment of the invention 1 makes, take after 3 months, symptom is obviously improved.In 30 people of clinical experiment, effective 15 people, effective 13 people, invalid 2 people, total effective rate 93.33%.
Claims (1)
1. promote a compositions for Plumbum removing, it is characterized in that percentage composition meter is composed of the following components by weight:
Rhizoma Chuanxiong 20%～50% Pfansteihl zinc 10%～30% heme iron 5%～20% activated calcium 10%～40% vitamin C 10%～30%
Wherein said heme iron and ascorbic part by weight are 1: 1.5～2.5
The compositions of above-mentioned promotion Plumbum removing is made up of following method:
(1) by above-mentioned weight proportion, often return water extraction process to extract Rhizoma Chuanxiong, make extractum, dry and pulverize, obtain extract fine powder;
(2) by above-mentioned weight proportion, Pfansteihl zinc, heme iron, activated calcium, vitamin C are mixed with above-mentioned (1) extract fine powder, stir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410233741.4A CN103977046A (en) | 2014-05-27 | 2014-05-27 | Composition for promoting lead removal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410233741.4A CN103977046A (en) | 2014-05-27 | 2014-05-27 | Composition for promoting lead removal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103977046A true CN103977046A (en) | 2014-08-13 |
Family
ID=51269373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410233741.4A Pending CN103977046A (en) | 2014-05-27 | 2014-05-27 | Composition for promoting lead removal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103977046A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105831771A (en) * | 2016-03-23 | 2016-08-10 | 江南大学 | Probiotics and microelement dietary supplement with function of alleviating lead toxicity |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006273735A (en) * | 2005-03-29 | 2006-10-12 | Ebs Kk | Harmful metal excretion accelerating activity composition and its manufacturing method |
| CN101461522A (en) * | 2007-12-20 | 2009-06-24 | 北京因科瑞斯医药科技有限公司 | Composition with function for promoting lead-expelling and method for preparing the same |
| CN103142946A (en) * | 2011-12-06 | 2013-06-12 | 王春晖 | Health-care medicine for expelling lead in human body |
| CN103211065A (en) * | 2013-05-10 | 2013-07-24 | 北京绿源求证科技发展有限责任公司 | Pabular health tea electuary for promoting lead excretion |
-
2014
- 2014-05-27 CN CN201410233741.4A patent/CN103977046A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006273735A (en) * | 2005-03-29 | 2006-10-12 | Ebs Kk | Harmful metal excretion accelerating activity composition and its manufacturing method |
| CN101461522A (en) * | 2007-12-20 | 2009-06-24 | 北京因科瑞斯医药科技有限公司 | Composition with function for promoting lead-expelling and method for preparing the same |
| CN103142946A (en) * | 2011-12-06 | 2013-06-12 | 王春晖 | Health-care medicine for expelling lead in human body |
| CN103211065A (en) * | 2013-05-10 | 2013-07-24 | 北京绿源求证科技发展有限责任公司 | Pabular health tea electuary for promoting lead excretion |
Non-Patent Citations (4)
| Title |
|---|
| 刘清等: "维生素C-钙配方制品对儿童驱铅作用研究", 《中国卫生检验杂志》, vol. 16, no. 2, 28 February 2006 (2006-02-28), pages 224 - 226 * |
| 范青生: "《保健食品配方原理与依据》", 31 January 2007, article "促进排铅功能", pages: 40 * |
| 赵佩琦: "《家庭生活小窍门》", 31 January 2005, article "可助排铅的食物", pages: 142 * |
| 陈兆和等: "复方排铅口服液治疗铅高婴幼儿166例", 《广东微量元素科学》, vol. 7, no. 8, 31 December 2000 (2000-12-31), pages 32 - 34 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105831771A (en) * | 2016-03-23 | 2016-08-10 | 江南大学 | Probiotics and microelement dietary supplement with function of alleviating lead toxicity |
| CN105831771B (en) * | 2016-03-23 | 2019-04-23 | 江南大学 | A kind of dietary supplements with the probiotics and microelement of alleviating lead poisoning sexual function |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN101297889B (en) | Chinese medicine preparation for treating foot-and-mouth disease and preparation method thereof | |
| CN102389473A (en) | Traditional Chinese medicine used for treating diabetic constipation | |
| CN102172374A (en) | Traditional Chinese medicine for treating hyperplasia of prostate | |
| CN102258628B (en) | Chinese medicinal composition with lead removal promoting effect | |
| CN103768529A (en) | Traditional Chinese medicine composition for treating postchole cystomy syndrome and application thereof | |
| CN100350954C (en) | Chinese medicine preparation for promoting lead-removal and its preparation process | |
| CN103705796A (en) | Medicinal composition for treating diarrhea, and preparation method thereof | |
| CN101548993B (en) | Application of Japanese climbing fern spore in preparing lead excretion medicines or health products | |
| CN103977046A (en) | Composition for promoting lead removal | |
| CN103444957A (en) | Health tea electuary for treating constipation based on food therapy | |
| CN102940839A (en) | Traditional Chinese medicine composition for treating chronic atrophic gastritis | |
| CN101972349A (en) | Traditional Chinese medicine for treating benign prostatic hyperplasia | |
| CN102389472A (en) | Traditional Chinese medicine for treating diabetic constipation | |
| CN102614344B (en) | Traditional Chinese medicine for treating qi-blood deficiency periodontitis, preparation method and administration method thereof | |
| CN103479960A (en) | Chronic Hepatitis B disease treatment Chinese herbal | |
| CN102114122A (en) | Traditional Chinese medicine for treating chronic prostatitis | |
| CN101884747B (en) | Traditional Chinese medicine for treating chronic nephritis | |
| CN102389474A (en) | Chinese medicine for treating diabetic constipation | |
| CN102294012A (en) | Chinese medicinal composition for treating diarrhoea | |
| CN101554426B (en) | Traditional Chinese medicine for treating diabetic obstipation | |
| CN101972426A (en) | Traditional Chinese medicine for treating chronic prostatitis | |
| CN101850020B (en) | Chinese medicament for treating chronic kidney failure | |
| CN103961384A (en) | Traditional Chinese medicinal composition for promoting lead removal and preparation method thereof | |
| CN104587280B (en) | A kind of medicament for the treatment of Rickets In Infants And Children |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140813 |