CN103948956A - Medical composite shaping restoration material layer for cavity - Google Patents
Medical composite shaping restoration material layer for cavity Download PDFInfo
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- CN103948956A CN103948956A CN201410125330.3A CN201410125330A CN103948956A CN 103948956 A CN103948956 A CN 103948956A CN 201410125330 A CN201410125330 A CN 201410125330A CN 103948956 A CN103948956 A CN 103948956A
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Abstract
The invention aims at providing a safe medical composite shaping restoration material layer for cavity, capable of effectively stopping bleeding, promoting healing, adsorbing the secretion and plasticize-shaping the umbilical region. The material layer comprises a medical PU sponge layer, an adsorption layer covering the periphery of the medical PU sponge layer, and an antibiotic protection layer positioned in the periphery of the adsorption layer, and the medical PU sponge layer is hot-pressed through a die to form a shape matching with the shape of the focal position of the cavity. The material layer can be applied to the field of medical apparatuses.
Description
Technical field
The present invention relates to a kind of cavity repair materials layer, relate in particular to the medical compound plastotype repair materials layer of a kind of neonatal umbilical cord.
Background technology
At present, along with the improving constantly of medical level and equipment, various physics operations are in a large amount of the carrying out of different department of each medical institutions.And postoperative tradition is protected the backward in technique of traumatic material, the Gospel that synchronously sophisticated equipment brings to patient.Neonatal umbilical cord nursing is very important postoperative care.After neonatal umbilical cord is cut off, just formed wound surface, this is that antibacterial is invaded an important door in neonate body, and the lighter can cause omphalitis, and severe one often causes septicemia and death, so the nursing of umbilical cord is very important.
Due to the particularity (recess) of umbilical cord formation wound surface, tradition care method uses alcohol wipe, be merely able to play the effect of interim sterilization, and traditional tourniquet, nursing plaster etc., because cannot useful effect in lesions position, for the functions of stanching and promoting healing of wound surface, adsorb secretions, prevent that umbilical hernia from not having effect substantially, so market there is no the Novel nursing means that can play functions of stanching and promoting healing, absorption secretions, umbilical part plastotype in Neonatal umbilical part nursing field at present.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, and a kind of safe, effective medical compound plastotype repair materials layer of cavity of functions of stanching and promoting healing, absorption secretions, umbilical part plastotype is provided.
The technical solution adopted in the present invention is: material layer of the present invention comprises medical PU spongy layer, is coated on the adsorption layer of described medical PU spongy layer periphery and is positioned at the antibacterial and protective layer of described adsorption layer periphery, and described medical PU spongy layer is made the shape matching with the shape of cavity lesions position by mould heat pressure.
Further, described medical PU spongy layer, adsorption layer and described antibacterial and protective layer are integrated through being hot pressed into.
Further, described antibacterial and protective layer is modified chitosan anti-bacteria material layer, nano silver antibacterial material layer, iodine ketone anti-biotic material layer or quaternary ammonium salt anti-biotic material layer.
Further, described adsorption layer is medical adsorption material layer, and the iodine sorption value of described medical adsorption material layer is 1200～3000mg/g.
Further, described antibacterial and protective layer is modified chitosan anti-bacteria material layer, and described modified chitosan anti-bacteria material layer is formed through blending by chitin fiber layer and nonwoven layer.
Further, the chitin fiber content of described modified chitosan anti-bacteria material layer is 3～99%.
Particularly, the chitin fiber content of described modified chitosan anti-bacteria material layer is 9%, and deacetylation is 99.9%.
The invention has the beneficial effects as follows: the present invention utilizes the slow resilience of medical PU sponge, anti-biotic material is delivered to as special in neonatal umbilical cord wound surface etc. and the indefinite form lesions position of cavity and is reached anti-inflammation and impel the effect of healing, the bad secretions of adsorbing material absorption wound surface simultaneously, for privileged sites wound healing provides actively good recovery environment, effectively accelerate wound healing, suppress the growth of pathogenic bacteria, to erosion, the refractory wound surface healing accelerations such as ulcer have remarkable meaning, and effectively prevent the superinfection that traditional material adhesion wound surface causes, at utmost reduce special wound surface cicatrization in the cavitys such as neonatal umbilical cord.
Brief description of the drawings
Fig. 1 is easy structure schematic diagram of the present invention.
Detailed description of the invention
As shown in Figure 1, the present invention includes medical PU spongy layer, be coated on the adsorption layer of described medical PU spongy layer periphery and be positioned at the antibacterial and protective layer of described adsorption layer periphery, described medical PU spongy layer is made the shape matching with the shape of cavity lesions position by mould heat pressure.Whole repair materials layer is fixed by the sticker fixed layer that is arranged on described medical PU spongy layer side.Described medical PU spongy layer, described adsorption layer and described antibacterial and protective layer are integrated through being hot pressed into.Described antibacterial and protective layer is modified chitosan anti-bacteria material layer, nano silver antibacterial material layer, iodine ketone anti-biotic material layer or quaternary ammonium salt anti-biotic material layer.In the present invention, described antibacterial and protective layer is modified chitosan anti-bacteria material layer, and described modified chitosan anti-bacteria material layer is formed through blending by chitin fiber layer and nonwoven layer.The chitin fiber content of described modified chitosan anti-bacteria material layer is 3～99%.Particularly, the chitin fiber content of described modified chitosan anti-bacteria material layer is 9%, and deacetylation is 99.9%.Described adsorption layer is medical adsorption material layer, and the iodine sorption value of described medical adsorption material layer is 1200～3000mg/g, and specifically choosing iodine sorption value is the strong enclosure material layer of medical suction of 1300 mg/g.
With specific embodiment, the present invention is further illustrated below.
embodiment mono-:
The present embodiment is the column that by mould, medical PU sponge is pressed into shape (10 ± 1) × (6 ± 1) mm close with neonatal umbilicus depression position size, again length and width are of a size of to the sticky medical PU sponge of the column column skin that is pressed on of medical strong adsorption layer (Medical carbon fiber) of (11 ± 1) × (7 ± 1) mm, again by sticky the modification of chitosan material layer of (12 ± 1) × (9 ± 1) the mm skin that is pressed on medical strong adsorption layer (Medical carbon fiber), by this coalition, according to medical institutions' requirement, packaging, sterilizing is stand-by.
embodiment bis-:
The present embodiment is the sticky medical PU sponge of the column column skin that is pressed on of medical strong adsorption layer (Medical carbon fiber) that the column that by mould, medical PU sponge is pressed into shape (12 ± 1) × (5 ± 1) mm close with the nasal cavity position size of being grown up is of a size of length and width (13 ± 1) × (6 ± 1) mm again, again by sticky the modification of chitosan layer of (14 ± 1) × (7 ± 1) the mm skin that is pressed on medical strong adsorption layer (Medical carbon fiber), by this coalition, according to medical institutions' requirement, packaging, sterilizing is stand-by.
embodiment tri-:
The present embodiment be by mould by medical PU sponge be pressed into pregnant age woman vagina in the column of close shape (48 ± 1) × (13 ± 1) mm of tract position size again length and width are of a size of to the sticky medical PU sponge of the column column skin that is pressed on of medical strong adsorption layer (Medical carbon fiber) of (49 ± 1) × (14 ± 1) mm, again by sticky the modification of chitosan material layer of (50 ± 1) × (15 ± 1) the mm skin that is pressed on medical strong adsorption layer (Medical carbon fiber), by this coalition, according to medical institutions' requirement, packaging, sterilizing is stand-by.
In above embodiment product be mainly used in neonatal umbilicus functions of stanching and promoting healing, absorption secretions, umbilical part plastotype and special surgical operation wound surface as the hemostasis of: polyp of nasal cavity excision, gynecological's physics operation, gynecological (leep, swash optical, electrical ring cutting etc.), drain, promoting healing with and the operation of tract physics before the aspect such as cleaning action.
Clinical use is summarized as follows:
1, newborn care aspect:
Treatment group: 36 routine patients without 1 example because of umbilical cord superinfection.Patient monitoring people readme: use after de-umbilicus, wound surface is dry and comfortable, occurs without omphalitis, umbilical hernia symptom, and easy to use, neonate degree of getting to know is high.5 days after operation weekly check: wound surface is clean dry and comfortable, pile up cicatrix without, shift to an earlier date 3-4 days than conventional therapy healing time.
Matched group: after the de-umbilicus of 36 routine patient's 12 example, secretions is more medical, and 4 examples are red and swollen medical, and 7 routine omphalitis are medical, and most of patients secretions is more.5 days after operation checks: protect traumatic material and be difficult to act on wound site, patient monitoring people is turned up for preventing umbilical cord, use voluntarily cotton balls to fill to stick together need to smear after normal saline infiltrates and just take off reluctantly, part wound causes secondary hemorrhage, has cicatrix to pile up and the umbilicus head omen of turning up.
2, gynecological's physics operation (leep, sharp optical, electrical ring cutting etc.)
Treatment group: without 1 example because of postoperative hemorrhage medical, without 1 routine postoperative infection.Patient's readme: postoperative secretions is less, and vagina is without sense of discomfort.Postoperative 1 weekly check: cervical mucosal, without obvious hyperemia, is dispersed in as seen new epithelize and covers, and shifts to an earlier date 3-4 days than conventional therapy healing time.
Matched group: 4 routine postoperative hemorrhages are more medical.The postoperative secretions of most of patients is more.Postoperative 1 weekly check: cervical mucosal is congested in various degree, has 6 routine secondary vaginal infection.
In the present invention, the shape that medical PU sponge can be made any identical lesions position according to the hot pressing of special lesions position feature is simultaneously effectively effectively sent antibacterial and protective layer and adsorption layer and is passed slight action by contact to lesions position, and patient's comfort level is high, have plastotype effect concurrently, it is splendid antibacterial that modification of chitosan material (specified molecular weight and composite than the composites of row) molecular structure and physicochemical property have this material, promoting healing, prevent the multiple effects such as sticky, thereby organically combine and make the medical compound plastotype repair materials of this novel cavity wound surface possess following performance and the mechanism of action with medical strong adsorption layer:
1, medical PU sponge can be made according to the hot pressing of special lesions position feature the shape of any identical lesions position, simultaneously effectively antibacterial and protective layer and adsorption layer are effectively sent and pass slight action by contact to lesions position, and patient's comfort level is high, has plastotype effect concurrently;
2, utilize the adsorption of medical strong adsorption layer, effectively the pathogenic bacterium absorption in cavity is attached on modified chitosan fiber;
3, anti-microbial property
Effectively antibacterial bacteriostatic of the material of the distinctive cation of modification of chitosan material and 50000 dalton units, the material of 2000 dalton's unit formula amounts provides antibacterial barrier layer.Pathogenic microorganism (as: pathogenic bacteria such as gram positive bacteria, Candida albicans, staphylococcus aureus) is adsorbed to modification of chitosan material layer by adsorption layer material, negative charge in the adsorbable bacterial cell of Zhunyang ion positive charge that modified chitosan fiber carries, there is flocculation, upset cell normal physiological activity, or in blocking-up bacterial body, transcribing of DNA copied, anti-bacteria breeding, plays good inhibitory action).
4, biocompatibility
Modification of chitosan material low-molecular-weight is high deacetylized, and spiral hinge molecular structure kept the active ingredient of the low and active amino of degree of crystallinity to the full extent, has excellent biocompatibility, nontoxic, non-stimulated to human-body safety, without sensitization.
In sum: the present invention is nontoxic, harmless, non-stimulated to human-body safety, absorption effectively improves wound surface and recovers environment, easy to use.The physical characteristic of this new composite wound surface material for quickly repairing self, reach the effect of auxiliary treatment, and the Related product such as traditional common medical adhesive-bonded fabric, single blending chitosan non-woven fabrics, antibiotic, Chinese medicine easily produces drug resistance and occupancy has incomparable advantage.
The present invention can be applicable to medical instruments field.
It should be noted that, above-mentionedly only describe the present invention with preferred embodiment, can not limit to interest field of the present invention at this point, therefore in the situation that not departing from inventive concept, the equivalence that the content of all utilizations description of the present invention and accompanying drawing part is carried out changes, and all reason is with being included within the scope of claim of the present invention.
Claims (7)
1. the medical compound plastotype repair materials layer of cavity, it is characterized in that: this material layer comprises medical PU spongy layer, is coated on the adsorption layer of described medical PU spongy layer periphery and is positioned at the antibacterial and protective layer of described adsorption layer periphery, described medical PU spongy layer is made the shape matching with the shape of cavity lesions position by mould heat pressure.
2. the medical compound plastotype repair materials layer of a kind of cavity according to claim 1, is characterized in that: described medical PU spongy layer, adsorption layer and described antibacterial and protective layer are integrated through being hot pressed into.
3. the medical compound plastotype repair materials layer of a kind of cavity according to claim 1, is characterized in that: described antibacterial and protective layer is modified chitosan anti-bacteria material layer, nano silver antibacterial material layer, iodine ketone anti-biotic material layer or quaternary ammonium salt anti-biotic material layer.
4. the medical compound plastotype repair materials layer of a kind of cavity according to claim 1, is characterized in that: described adsorption layer is medical adsorption material layer, and the iodine sorption value of described medical adsorption material layer is 1200～3000mg/g.
5. the medical compound plastotype repair materials layer of a kind of cavity according to claim 3, it is characterized in that: described antibacterial and protective layer is modified chitosan anti-bacteria material layer, described modified chitosan anti-bacteria material layer is formed through blending by chitin fiber layer and nonwoven layer.
6. the medical compound plastotype repair materials layer of a kind of cavity according to claim 5, is characterized in that: the chitin fiber content of described modified chitosan anti-bacteria material layer is 3～99%.
7. the medical compound plastotype repair materials layer of a kind of cavity according to claim 6, is characterized in that: the chitin fiber content of described modified chitosan anti-bacteria material layer is 9%, and deacetylation is 99.9%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410125330.3A CN103948956A (en) | 2014-04-01 | 2014-04-01 | Medical composite shaping restoration material layer for cavity |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410125330.3A CN103948956A (en) | 2014-04-01 | 2014-04-01 | Medical composite shaping restoration material layer for cavity |
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| CN103948956A true CN103948956A (en) | 2014-07-30 |
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| CN201410125330.3A Pending CN103948956A (en) | 2014-04-01 | 2014-04-01 | Medical composite shaping restoration material layer for cavity |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101340871A (en) * | 2004-12-23 | 2009-01-07 | 赫姆孔公司 | Antimicrobial barriers, systems, and methods formed from hydrophilic polymer structures such as chitosan |
| CN101816803A (en) * | 2009-07-21 | 2010-09-01 | 王剑峰 | Disposable female biopolymer adsorbing suppository with functions of stanching and promoting healing |
| US20110237994A1 (en) * | 2010-03-25 | 2011-09-29 | Combat Medical Systems, Llc | Void-filling wound dressing |
| CN203874166U (en) * | 2014-04-01 | 2014-10-15 | 王剑峰 | Medical composite material layer for molding and repairing cavity |
-
2014
- 2014-04-01 CN CN201410125330.3A patent/CN103948956A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101340871A (en) * | 2004-12-23 | 2009-01-07 | 赫姆孔公司 | Antimicrobial barriers, systems, and methods formed from hydrophilic polymer structures such as chitosan |
| CN101816803A (en) * | 2009-07-21 | 2010-09-01 | 王剑峰 | Disposable female biopolymer adsorbing suppository with functions of stanching and promoting healing |
| US20110237994A1 (en) * | 2010-03-25 | 2011-09-29 | Combat Medical Systems, Llc | Void-filling wound dressing |
| CN203874166U (en) * | 2014-04-01 | 2014-10-15 | 王剑峰 | Medical composite material layer for molding and repairing cavity |
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Application publication date: 20140730 |