CN103919825A - Compound radix bupleuri combination medicine used for cold and preparation method - Google Patents
Compound radix bupleuri combination medicine used for cold and preparation method Download PDFInfo
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- CN103919825A CN103919825A CN201310008521.7A CN201310008521A CN103919825A CN 103919825 A CN103919825 A CN 103919825A CN 201310008521 A CN201310008521 A CN 201310008521A CN 103919825 A CN103919825 A CN 103919825A
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- radix bupleuri
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- catechin
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- tea
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Abstract
The invention discloses a compound radix bupleuri combination medicine used for cold and a preparation method. The combination medicine includes microencapsulated radix bupleuri with a weight percentage being 35%-65% and microencapsulated catechin-tea flavonoids crystals. Because the medicine is processed to be in nanoscale, active ingredients in the medicine are easy to absorb and medicinal effects of the medicine are increased. The beneficial effects of the invention are that the radix bupleuri is processed into a traditional Chinese medicine powder in nanoscale fineness and is manufactured into a compound with saikosaponin, radix bupleuri flavone, ginger and the like, so that nutrition components in the medicine can be absorbed and utilized efficiently. The radix bupleuri is subjected to an emulsification shearing process through microencapsulated liposome so that the radix bupleuri is effectively prevented from oxidative deterioration due to air. The microencapsulated catechin-tea flavone crystal can effectively kill microbes such as aspergillus flavus and dermatophagoides farinae and the like in an infected radix bupleuri during a storage process. Silver ions, which are safe and nontoxic, can absorb microbes and viruses in human organs and cells.
Description
Technical field
The present invention relates to a kind of drug products, relate in particular to a kind of Radix Bupleuri compound recipe flu composition of medicine and preparation method.
Background technology
The main effective ingredient of Radix Bupleuri is saikoside.What up to the present, Yi Bei the world of medicine accepted extensively is that saikoside has antiinflammatory, anti-flu, the effect of bringing down a fever, protects the liver, reduces the effects such as blood cholesterol and blood fat.The present invention is Radix Bupleuri compounded anti-cold class composition of medicine, and main component is saikoside and bupleurum flavone and catechin.The effective ingredient of its medicine is higher than common drug on market, so dose is little, and anti-flu and the effect of bringing down a fever are good.
Exactly because, also there is on the market the multiple product that Radix Bupleuri is raw material of take in the function that Radix Bupleuri itself is abundant.But, current Radix Bupleuri is all the coarse granules that adopt common grinding and produce through 80-200 object sieve conventionally, this processing method is not as adopting the Chinese medicine powder that Radix Bupleuri is processed into nanoscale fineness, our invention is to be processed into nanoscale, play the effect of antiinflammatory, antiviral, preventing cold, make the method for complex, improve drug effect.
In addition,, because current Chaihu product is exposed in air, material is wherein very easily oxidized; In the process that Chaihu product is stored in a warehouse, the very easily pollution of microbial contamination, especially Aspergillus flavus and dust mite, the health that has serious threat eater of these microorganisms.
The present invention consults " a kind of preparation method of saikoside ", patent publication No.: CN101229204A with reference to the producing of saikoside of high-load.The bupleurum flavone of high-load is produced and is consulted " bupleurum flavone composition of a kind of anti-cold virus and preparation method thereof ", patent publication No.: CN1180781C.Our invention is in a kind of compound formulation, to add Rhizoma Zingiberis Recens, increased cold removing effect, has added catechin, and catechin has the effect that suppresses virus activity, effectively flu-prevention.
Summary of the invention
For the problem of above-mentioned existence, the object of this invention is to provide a kind of Radix Bupleuri product that can be fully absorbed, carry out microencapsulation processing, prevent oxidizedly, be beneficial to the storage time that extends; Catechin-tea flavone the crystal that adds microencapsulation, can play the effect of sterilization and anti-bacteria and anti-virus effectively.
The object of the invention is to be achieved through the following technical solutions:
A compositions that contains Radix Bupleuri, comprises microencapsulation Radix Bupleuri, and the percentage by weight of described microencapsulation Radix Bupleuri is 35%-65%, wherein, also comprises microencapsulation catechin-tea pyrite crystal, and the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 20%-30%.
The above-mentioned compositions that contains Radix Bupleuri, wherein, the percentage by weight of described microencapsulation Radix Bupleuri is 40%-55%, the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 40%-55%.
The above-mentioned compositions that contains Radix Bupleuri, wherein, also comprises silver ion, and the percentage by weight of described silver ion is 0.3%-0.6%.
Saikoside, bupleurum flavone, catechin are processed into the Chinese medicine powder of nanoscale fineness, coordinate carboxymethyl starch sodium, carbon dioxide, magnesium stearate, Rhizoma Zingiberis Recens etc., make effective formula, various medicated powder according to nano bupleurum saponin, bupleurum flavone 60g, carboxymethyl starch sodium 10g, carbon dioxide 18g, magnesium stearate 0.5g, Rhizoma Zingiberis Recens 2g proportioning preparation of nano level fineness add catechin 10 g, mix and make solution, extraction is concentrated, spraying is dry, pulverize, conventional method is made hard capsule and tablet product.
Compared with the prior art, beneficial effect of the present invention is: Radix Bupleuri is processed into the Chinese medicine powder of nanoscale fineness, and wherein nutrition can be absorbed and utilize efficiently; Radix Bupleuri progress emulsifying with microencapsulation liposome after to micronizing is sheared, and can effectively prevent Radix Bupleuri ingress of air oxidation deterioration; Catechin-tea flavone the crystal that adds microencapsulation, can kill the microorganisms such as Aspergillus flavus that Radix Bupleuri infects in storage process and dust mite effectively, improves the antiviral ability of human antimicrobial simultaneously; Add silver ion, can reach absorption human organ and intracellular microorganism and virus, silver ion safety non-toxic, is a kind of protective agent of human body cell and Radix Bupleuri and catechin simultaneously.
The specific embodiment
Below in conjunction with concrete operations embodiment, the invention will be further described.
A kind of compositions that contains Radix Bupleuri of the present invention, comprise microencapsulation Radix Bupleuri, the percentage by weight of described microencapsulation Radix Bupleuri is 35%-65%, wherein, also comprise microencapsulation catechin-tea pyrite crystal, the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 20%-30%.Wherein, take Radix Bupleuri as raw material, adopt micronizing unit to carry out micronizing, when Radix Bupleuri, through charging aperture spiral, send in pulverizing chamber, be subject to high speed impact and the shearing of grating disk, the while is also subject to the dither of eddy current generation and is pulverized.Powder body after pulverizing is crossed spreader and is covered into grading room under suction function.Due to the high speed rotating of grading wheel, powder body is subject to the effect of air force and centrifugal force simultaneously.When centrifugal force > air force, illustrate that powder body is greater than predefined Cut size particle size, powder body is got rid of to be returned to pulverizing chamber to tapered sleeve and continues to pulverize, and the qualified powder body of the pulverizing that meets the standard of setting in advance, now air force > centrifugal force is subject to dynamic action, after entering the pipeline that gathers materials, to subsidiary engine, be discharged from, after collection, become the Radix Bupleuri powder body of micronizing.Adopt the method for micronizing to process Radix Bupleuri raw material, thereby obtain 300-500 object micron and nano level ultra micro Radix Bupleuri powder body, this ultra micro Radix Bupleuri powder body can enter cyton in human body, reaches kill bacteria and virus, improves the effect of body immunity; Afterwards, resulting ultra micro Radix Bupleuri powder body is carried out to microencapsulation processing: take albumen NP and carbohydrate CA, CB as wall material making microencapsulation liposome, the ultra micro Radix Bupleuri powder body of simultaneously take is core, and microencapsulation liposome is that wall material carries out emulsifying and shears and make microencapsulation Radix Bupleuri.
Various medicated powder according to nano bupleurum saponin, bupleurum flavone 60g, carboxymethyl starch sodium 10g, carbon dioxide 18g, magnesium stearate 0.5g, Rhizoma Zingiberis Recens 2g proportioning preparation of nano level fineness add catechin 10g, mix and make solution, extraction is concentrated, spraying is dry, pulverize, conventional method is made hard capsule and tablet product.On this basis, adding percentage by weight is microencapsulation catechin-tea flavone crystal of 20%-30%, after mix homogeneously, can make capsule or tablet by capsule machine or tablet machine.
For obtaining better sterilization and anti-bacteria and anti-virus effect, bring into play better the nutrition of Radix Bupleuri and the anti-bacteria and anti-virus effect of catechin-tea flavone, can select to add percentage by weight is the silver ion of 0.3%-0.6%.
Above specific embodiments of the invention be have been described in detail, but the present invention is not restricted to specific embodiment described above, it is just as example.To those skilled in the art, any equivalent modifications that this is carried out and alternative also all among category of the present invention.Therefore, equalization conversion and the modification done without departing from the spirit and scope of the invention, all should contain within the scope of the invention.
Claims (4)
1. Radix Bupleuri compound recipe flu composition of medicine and preparation method, comprise microencapsulation Radix Bupleuri, the percentage by weight of described microencapsulation Radix Bupleuri is 35%-65%, it is characterized in that, also comprise microencapsulation catechin-tea pyrite crystal, the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 20%-30%.
2. the compositions that contains Radix Bupleuri according to claim 1, is characterized in that, the percentage by weight of described microencapsulation Flos Camelliae Japonicae powder is 40%-55%, and the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 45%-50%.
3. the compositions that contains Radix Bupleuri according to claim 1 and 2, is characterized in that, also comprises silver ion, and the percentage by weight of described silver ion is 0.3%-0.6%.
4. a compositions that contains Radix Bupleuri, comprises microencapsulation Radix Bupleuri, and the percentage by weight of described microencapsulation Radix Bupleuri is 35%-65%, wherein, also comprises microencapsulation catechin-tea pyrite crystal, and the percentage by weight of described microencapsulation catechin-tea pyrite crystal is 20%-30%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310008521.7A CN103919825A (en) | 2013-01-10 | 2013-01-10 | Compound radix bupleuri combination medicine used for cold and preparation method |
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| CN201310008521.7A CN103919825A (en) | 2013-01-10 | 2013-01-10 | Compound radix bupleuri combination medicine used for cold and preparation method |
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| CN103919825A true CN103919825A (en) | 2014-07-16 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117281884A (en) * | 2023-11-24 | 2023-12-26 | 山东天宇生物科技有限公司 | Traditional Chinese medicine composition for preventing chicken aflatoxin poisoning and preparation process thereof |
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2013
- 2013-01-10 CN CN201310008521.7A patent/CN103919825A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117281884A (en) * | 2023-11-24 | 2023-12-26 | 山东天宇生物科技有限公司 | Traditional Chinese medicine composition for preventing chicken aflatoxin poisoning and preparation process thereof |
| CN117281884B (en) * | 2023-11-24 | 2024-03-01 | 山东畜牧兽医职业学院 | Traditional Chinese medicine composition for preventing chicken aflatoxin poisoning and preparation process thereof |
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Application publication date: 20140716 |