CN103893484A - Traditional Chinese medicine composition for treating pruritus cutanea after hematodialysis - Google Patents
Traditional Chinese medicine composition for treating pruritus cutanea after hematodialysis Download PDFInfo
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- CN103893484A CN103893484A CN201410138610.8A CN201410138610A CN103893484A CN 103893484 A CN103893484 A CN 103893484A CN 201410138610 A CN201410138610 A CN 201410138610A CN 103893484 A CN103893484 A CN 103893484A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating pruritus cutanea after hematodialysis. The pruritus cutanea after hematodialysis is caused by damp according to traditional Chinese medicine; the pruritus cutanea of uremia is mainly caused by blood-insufficiency damp, the damp toxin is accumulated in striae and interstitial space and causes that the skin is not moistened and nourished. The traditional Chinese medicine composition is characterized in that the traditional Chinese medicines capable of eliminating dampness and detoxifying, promoting circulation and removing stasis, and warmly invigorating kidney Yang are innovatively selected, including hairy grape stem, glandular showy himalayahoneysuckle herb, laxflower pottsia root, evans begonia root, convallaria majalis, ventilago leiocarpa benth, berb of wusheng clematis, agastache rugosus and shrubby cordyline flower. The clinical test shows that the curing rate and the total effective rate of the treatment group respectively reach 40.0% and 80.0%, which are obviously superior to those of the control group.
Description
Technical field
The invention belongs to medical sanitary technology field, be specifically related to a kind of Chinese medicine composition, relate in particular to a kind for the treatment of Chinese medicine composition of skin pruritus after hemodialysis.
Background technology
The whole patient who enters hemodialysis latter stage of chronic renal failure is in cumulative year after year, occur that after hemodialysis skin pruritus is the common skin symptom of Maintenance Hemodialysis Patients, the reason of chronic kidney hypofunction skin pruritus is still not exclusively clear at present, Recent study shows blood urea nitrogen may be with renal failure time, flesh liver, the metabolite retentions such as uric acid, to skin irritation, smegma reduces and sweat gland atrophy causes xerosis cutis relevant, also likely with secondary hyperparathyroidism, calcium and phosphorus metabolism disorder, hypervitaminosis A, the allergy of heparin and dialyzer composition, and the normal blood middle molecule toxins that is difficult to appear the accumulating in vivo of dialysing is relevant, therefore think how plain coefficient result.Doctor trained in Western medicine is often with Loratadine treatment or the treatment of change dialysis mode, but curative effect is still dissatisfied.Inventor, through clinical practice for many years, utilizes treatment by Chinese herbs skin pruritus after hemodialysis, economical and practical, easy to operate, and patient can carry out by Yu Jiazhong, and evident in efficacy.
Summary of the invention
The object of this invention is to provide a kind for the treatment of Chinese medicine composition of skin pruritus after hemodialysis." itch and come from wind " from motherland's medical angle, Skin Itch in Uremia Patients is take wind syndrome due to blood-deficiency as this, and noxious dampness is strongly fragrant in space between skin and muscles, and skin loses in moistening and supports as mark.Chinese traditional treatment is with eliminating damp, detoxifying, and blood circulation promoting and blood stasis dispelling, weeds out the old and bring forth the new, the kidney invigorating warming YANG, and invigorating the spleen and benefiting QI, makes just to win heresy and moves back, and water Shi Hangqichang road, take the turbid source of the waterproof poison stasis of blood as the rule for the treatment of.Be just accord with the meaning of " control wind and first control blood, blood wind is from going out ".
Treatment is a Chinese medicine composition for skin pruritus after hemodialysis, and this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Anemones vitifoliae 6-9 part, Herba Leycesteriae stenosepalae 9-15 part, Radix Pottsiae Laxiflorae 10-15 part, Radix Bischofiae Javanicae 10-16 part, Herba Convallariae 3-9 part, Radix seu Caulis Verntilaginis Leiocarpae 15-30 part, Herba Clematidis Huchouensis 12-15 part, Herba Pogostemonis 6-12 part, Flos Cycadis Revolute 30-60 part.
Preferably, 7 parts of Herba Anemones vitifoliaes, 12 parts of Herba Leycesteriae stenosepalae, 13 parts of Radix Pottsiae Laxifloraes, 13 parts of Radix Bischofiae Javanicaes, 6 parts of Herba Convallariaes, 22 parts of Radix seu Caulis Verntilaginis Leiocarpae, 14 parts of Herba Clematidis Huchouensiss, 9 parts of Herba Pogostemoniss, 45 parts of Flos Cycadis Revolutes.
Preparation method is made decoction by above-mentioned Chinese medicine by traditional method.
In side: Herba Anemones vitifoliae clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, hemostasis, wind-damp dispelling; Herba Leycesteriae stenosepalae dampness removing, antiinflammatory, invigorate blood circulation; Radix Pottsiae Laxiflorae blood circulation, evil-wind expelling and dampness removing; Radix Bischofiae Javanicae blood circulation promoting and blood stasis dispelling, clearing away heat to stop bleeding; Herba Convallariae warming YANG to promote diuresis, promoting blood circulation by removing wind; Radix seu Caulis Verntilaginis Leiocarpae benefiting vital QI and blood, dispelling, collateral-activating; Herba Clematidis Huchouensis dispels the wind, subsides a swelling; Herba Pogostemonis damp eliminating, ward off turbid and in, fast gas; Flos Cycadis Revolute promoting blood circulation by removing blood stasis.
Clinical data
1, all cases of physical data are my institute calendar year 2001 February～2009 year Augusts, outpatient service and Maintenance Hemodialysis Patients totally 60 examples of being in hospital, all there are refractory pruritus and xerosis cutis in various degree, desquamation, erythra etc., companion's hypertension, anemia and electrolyte disturbance in various degree.Be divided at random 2 groups, wherein treatment group 30 examples, male 17 examples, female's 13 examples, 25～79 years old age, on average (47.2 ± 14.9) year, protopathy comprises chronic glomerulonephritis 12 examples, diabetic nephropathy 5 examples, hypertensive renal damage 4 examples, lupus nephritis 2 examples, Adult Polycystic Kidney 7 examples, on average dialyse 3 years.Light-duty 14 examples of skin pruritus, medium-sized 10 examples, heavy 6 examples; The skin pruritus course of disease is the shortest 1.3 months, the longest 7 months, average 2.9 months.Matched group 30 examples, male 17 examples, female's 13 examples, 20～78 years old age, average (46.7 ± 15.7) year.Protopathy comprises chronic glomerulonephritis 10 examples, diabetic nephropathy 6 examples, hypertensive cerebral renal damage 5 examples, lupus nephritis 3 examples, Adult Polycystic Kidney 4 examples, drug-induced renal impairment: 2 examples.Light-duty 15 examples of skin pruritus, medium-sized 11 examples, heavy 4 examples; The skin pruritus course of disease is the shortest 1.3 months, the longest 5.4 months, average 2.8 months.
2, diagnostic criteria selects to meet the patient that 1. following condition meets the diagnostic criteria of chronic renal failure in " nephrology " and serum creatinine > 700I μ mol/L and maintain conventional hemodialysis (CHD); 2. meet " modern dermatological " skin pruritus diagnostic criteria: there is skin pruritus, but without the dermatosis of former skin lesion; 3. skin pruritus and the eliminating got rid of due to other reasons are associated with serious cardio cerebrovascular affection person.
3, Therapeutic Method treatment group: patient takes Chinese medicine composition of the present invention, take Herba Anemones vitifoliae 7g, Herba Leycesteriae stenosepalae 12g, Radix Pottsiae Laxiflorae 13g, Radix Bischofiae Javanicae 13g, Herba Convallariae 6g, Radix seu Caulis Verntilaginis Leiocarpae 22g, Herba Clematidis Huchouensis 14g, Herba Pogostemonis 9g, Flos Cycadis Revolute 45g decocting extracting juice, 1 dose of every day, decocting, to 600ml, divides 3 inferior to taking medicine after meal.Matched group: patient gives 1% Calamine Lotion, be outward coated with skin 2-3 every day, and all treating for two groups 4 weeks is a course for the treatment of.
4, curative effect determinate standard is cured: pruritus transference cure, and Secondary cases skin lesion disappears; Effective: pruritus symptom obviously alleviates, Secondary cases skin lesion disappears 80%; Take a turn for the better: pruritus symptom alleviates, Secondary cases skin lesion 50% left and right of disappearing; Invalid: pruritus symptom is without alleviating or increasing the weight of, the Secondary cases skin lesion < 50% that disappears.
5, curative effect comparison after the course for the treatment of of two groups of therapeutic outcomes treatment: treatment group 30 examples, wherein cure 12 examples (40.0%), effective 7 examples (23.3%), 5 examples that take a turn for the better (16.7%), invalid 6 examples (20.0%) total effective rate 80.0%; Matched group 30 examples, wherein cure 7 examples (23.3%), effective 8 examples (26.7%), 4 examples that take a turn for the better (13.3%), invalid 11 examples (36.7%), total effective rate 63.3%.Two groups of comparisons, treatment group obvious effective rate, total effective rate are obviously better than matched group, have comparability.P＜0.05。
The specific embodiment
Embodiment mono-: take Herba Anemones vitifoliae 7g, Herba Leycesteriae stenosepalae 12g, Radix Pottsiae Laxiflorae 13g, Radix Bischofiae Javanicae 13g, Herba Convallariae 6g, Radix seu Caulis Verntilaginis Leiocarpae 22g, Herba Clematidis Huchouensis 14g, Herba Pogostemonis 9g, Flos Cycadis Revolute 45g, above-mentioned Chinese medicine is made to decoction by traditional method.
Embodiment bis-: take Herba Anemones vitifoliae 6g, Herba Leycesteriae stenosepalae 15g, Radix Pottsiae Laxiflorae 10g, Radix Bischofiae Javanicae 16g, Herba Convallariae 3g, Radix seu Caulis Verntilaginis Leiocarpae 15g, Herba Clematidis Huchouensis 12g, Herba Pogostemonis 12g, Flos Cycadis Revolute 60g, above-mentioned Chinese medicine is made to decoction by traditional method.
Embodiment tri-: take Herba Anemones vitifoliae 9g, Herba Leycesteriae stenosepalae 9g, Radix Pottsiae Laxiflorae 15g, Radix Bischofiae Javanicae 10g, Herba Convallariae 9g, Radix seu Caulis Verntilaginis Leiocarpae 30g, Herba Clematidis Huchouensis 15g, Herba Pogostemonis 6g, Flos Cycadis Revolute 30g, above-mentioned Chinese medicine is made to decoction by traditional method.
Claims (2)
1. treat a Chinese medicine composition for skin pruritus after hemodialysis, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Anemones vitifoliae 6-9 part, Herba Leycesteriae stenosepalae 9-15 part, Radix Pottsiae Laxiflorae 10-15 part, Radix Bischofiae Javanicae 10-16 part, Herba Convallariae 3-9 part, Radix seu Caulis Verntilaginis Leiocarpae 15-30 part, Herba Clematidis Huchouensis 12-15 part, Herba Pogostemonis 6-12 part, Flos Cycadis Revolute 30-60 part.
A kind for the treatment of according to claim 1 after hemodialysis the Chinese medicine composition of skin pruritus it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: 7 parts of Herba Anemones vitifoliaes, 12 parts of Herba Leycesteriae stenosepalae, 13 parts of Radix Pottsiae Laxifloraes, 13 parts of Radix Bischofiae Javanicaes, 6 parts of Herba Convallariaes, 22 parts of Radix seu Caulis Verntilaginis Leiocarpae, 14 parts of Herba Clematidis Huchouensiss, 9 parts of Herba Pogostemoniss, 45 parts of Flos Cycadis Revolutes.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645069A (en) * | 2015-02-10 | 2015-05-27 | 青岛市市立医院 | Formula of Chinese medicament for treating hemodialysis complications |
| CN104666639A (en) * | 2015-02-10 | 2015-06-03 | 青岛市市立医院 | Traditional Chinese medicine formula for treating pruritus cutanea after hematodialysis |
| CN104666597A (en) * | 2015-02-10 | 2015-06-03 | 青岛市市立医院 | Traditional Chinese medicine emulsifiable paste for treating pruritus cutanea after hematodialysis |
| CN104940503A (en) * | 2015-05-31 | 2015-09-30 | 相丽 | Traditional Chinese medicine combination for treating itchy skins of patients undergoing hemodialysis |
| CN105381345A (en) * | 2015-11-17 | 2016-03-09 | 杨继丽 | Traditional Chinese medicine fumigating and washing agent for treating uremia skin itch and nursing method |
| CN105381089A (en) * | 2015-11-17 | 2016-03-09 | 邵开艳 | Traditional Chinese medicine lotion for treating skin itch of uremia patient and nursing method |
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| CN101537123A (en) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | Pharmaceutical composition for curing skin tinea and preparation method thereof |
| CN101664482A (en) * | 2009-07-24 | 2010-03-10 | 温益雄 | Externally-applied Zhuang medicine for treating beriberi and skin pruritus and preparation method thereof |
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2014
- 2014-03-30 CN CN201410138610.8A patent/CN103893484A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101537123A (en) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | Pharmaceutical composition for curing skin tinea and preparation method thereof |
| CN101664482A (en) * | 2009-07-24 | 2010-03-10 | 温益雄 | Externally-applied Zhuang medicine for treating beriberi and skin pruritus and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645069A (en) * | 2015-02-10 | 2015-05-27 | 青岛市市立医院 | Formula of Chinese medicament for treating hemodialysis complications |
| CN104666639A (en) * | 2015-02-10 | 2015-06-03 | 青岛市市立医院 | Traditional Chinese medicine formula for treating pruritus cutanea after hematodialysis |
| CN104666597A (en) * | 2015-02-10 | 2015-06-03 | 青岛市市立医院 | Traditional Chinese medicine emulsifiable paste for treating pruritus cutanea after hematodialysis |
| CN104940503A (en) * | 2015-05-31 | 2015-09-30 | 相丽 | Traditional Chinese medicine combination for treating itchy skins of patients undergoing hemodialysis |
| CN105381345A (en) * | 2015-11-17 | 2016-03-09 | 杨继丽 | Traditional Chinese medicine fumigating and washing agent for treating uremia skin itch and nursing method |
| CN105381089A (en) * | 2015-11-17 | 2016-03-09 | 邵开艳 | Traditional Chinese medicine lotion for treating skin itch of uremia patient and nursing method |
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