CN103874763A - 从胎儿组织制备亲代细胞库 - Google Patents

从胎儿组织制备亲代细胞库 Download PDF

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Publication number
CN103874763A
CN103874763A CN201280034452.0A CN201280034452A CN103874763A CN 103874763 A CN103874763 A CN 103874763A CN 201280034452 A CN201280034452 A CN 201280034452A CN 103874763 A CN103874763 A CN 103874763A
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CN
China
Prior art keywords
fetal
cells
tissue
skin
cartilage
Prior art date
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Pending
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CN201280034452.0A
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English (en)
Chinese (zh)
Inventor
L·A·劳伦-阿普尔盖特
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CT HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
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CT HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
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Publication of CN103874763A publication Critical patent/CN103874763A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/066—Tenocytes; Tendons, Ligaments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
CN201280034452.0A 2011-07-11 2012-07-10 从胎儿组织制备亲代细胞库 Pending CN103874763A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11173452.1 2011-07-11
EP11173452A EP2546335A1 (en) 2011-07-11 2011-07-11 Foetal epiphyseal chondrocyte (FEC) parental cell bank
PCT/IB2012/053512 WO2013008174A1 (en) 2011-07-11 2012-07-10 Preparation of parental cell bank from foetal tissue

Publications (1)

Publication Number Publication Date
CN103874763A true CN103874763A (zh) 2014-06-18

Family

ID=46717923

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280034452.0A Pending CN103874763A (zh) 2011-07-11 2012-07-10 从胎儿组织制备亲代细胞库

Country Status (7)

Country Link
US (2) US8986678B2 (https=)
EP (2) EP2546335A1 (https=)
JP (1) JP5964956B2 (https=)
CN (1) CN103874763A (https=)
ES (1) ES2654292T3 (https=)
PL (1) PL2732030T3 (https=)
WO (1) WO2013008174A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2546335A1 (en) 2011-07-11 2013-01-16 Centre Hospitalier Universitaire Vaudois (CHUV) Foetal epiphyseal chondrocyte (FEC) parental cell bank
CN104789524A (zh) * 2015-04-30 2015-07-22 四川大学 骨质疏松大鼠原代成骨细胞分离培养方法及应用
KR101836475B1 (ko) * 2016-08-02 2018-03-08 아주대학교산학협력단 연골 재생용 조성물 및 이의 제조방법
FR3100652A1 (fr) 2019-09-06 2021-03-12 Schneider Electric Industries Sas Transformateur multi-secondaire

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008128304A1 (en) * 2007-04-24 2008-10-30 The University Of Western Australia Tenocyte containing bioscaffolds and treatment using the same
FR2921668A1 (fr) * 2007-09-28 2009-04-03 Univ Bretagne Occidentale Etab Nouvelles compositions lipophiles et leurs utilisations.
EP2546335A1 (en) 2011-07-11 2013-01-16 Centre Hospitalier Universitaire Vaudois (CHUV) Foetal epiphyseal chondrocyte (FEC) parental cell bank

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANTONIO CARRASCOSA ET AL.: "Morphologic and Metabolic Development of Human Fetal Epiphyseal Chondrocytes in Primary Culture", 《PEDIATRIC RESEARCH》 *
BRINK HE ET AL.: "Influence of serum on adult and fetal dermal fibroblast migration, adhesion, and collagen expression", 《IN VITRO CELL DEV BIOL ANIM.》 *
MAFFULLI N ET AL.: "Tenocytes from ruptured and tendinopathic achilles tendons produce greater quantities of type III collagen than tenocytes from normal achilles tendons. An in vitro model of human tendon healing", 《AM J SPORTS MED》 *

Also Published As

Publication number Publication date
JP2014520546A (ja) 2014-08-25
EP2732030B1 (en) 2017-09-27
US9434923B2 (en) 2016-09-06
PL2732030T3 (pl) 2018-07-31
JP5964956B2 (ja) 2016-08-03
ES2654292T3 (es) 2018-02-13
US20150152388A1 (en) 2015-06-04
EP2546335A1 (en) 2013-01-16
WO2013008174A1 (en) 2013-01-17
EP2732030A1 (en) 2014-05-21
HK1198179A1 (en) 2015-03-13
US20140193377A1 (en) 2014-07-10
US8986678B2 (en) 2015-03-24

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Application publication date: 20140618

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