CN103860947B - A kind of medicament for the treatment of alopecia totalis and alopecia universalis - Google Patents
A kind of medicament for the treatment of alopecia totalis and alopecia universalis Download PDFInfo
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- CN103860947B CN103860947B CN201410135389.0A CN201410135389A CN103860947B CN 103860947 B CN103860947 B CN 103860947B CN 201410135389 A CN201410135389 A CN 201410135389A CN 103860947 B CN103860947 B CN 103860947B
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Abstract
The present invention relates to a kind of medicament for the treatment of alopecia totalis and alopecia universalis, it is made up of the material of following weight proportioning: Herba Anagallidis Arvensis, Folium Rhododendri Mucronati, Radix seu herba Heteropogonis Contorti, Semen Ciceris Arietini, Herba Commelinae Diffusae, work as medicine, Arillus Longan, Radix Stephaniae hemandifoliae, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Averrhoae Carambolae, fernleaf hedge bamboo, the Radix Pulsatillae, Herba Iresines Herbstii, Herba Blumeae Lacerae, Radix Maesae Japonicae, Rabdosia rubescens, Herba Glechomae, Radix et Rhizoma Iridis Sanguineae, Radix seu Herba Pegaeophytonis Scapiflori, Herba Polygalae Japonicae, Herba suadeae glaucae, Rhizoma Imperatae, the Fructus Kochiae, Diplazium lanceum (Thunb), Folium Sauropi, Herba Agrimoniae, Herba Euphorbiae Humifusae, Cacumen Tamaricis, Radix Cynanchi Atrati, Caulis Bambusae In Taenia, Semen Cassiae, Pericarpium Zanthoxyli, Herba Lycopodii, Ophicalcitum, Herba abutili indici, Flos Celosiae Cristatae, Celastrus gemmatus Loes. and Pericarpium Citri Reticulatae Viride.Whole compositions of the medicament for the treatment of alopecia totalis of the present invention and alopecia universalis are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of alopecia totalis and alopecia universalis.
Background technology
Alopecia areata is clinical common skin diseases, can be divided into: single stove alopecia areata, multifocal alopecia areata, alopecia totalis and alopecia universalis 4 types.Wherein alopecia totalis and alopecia universalis are comparatively obstinate, are the serious types of alopecia areata, relative difficulty in treatment, and easily recur.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of alopecia totalis and alopecia universalis.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of alopecia totalis and alopecia universalis, it is made up of the material of following weight proportioning: Herba Anagallidis Arvensis 10 parts, Folium Rhododendri Mucronati 10 parts, Radix seu herba Heteropogonis Contorti 15 parts, Semen Ciceris Arietini 10 parts, Herba Commelinae Diffusae 10 parts, when medicine 6 parts, Arillus Longan 10 parts, Radix Stephaniae hemandifoliae 10 parts, Ilex purpurea Hassk.[I.chinensis Sims 15 parts, Fructus Averrhoae Carambolae (Classification system AverrhoacarambolaL.) 20 parts, fernleaf hedge bamboo 10 parts, the Radix Pulsatillae 10 parts, Herba Iresines Herbstii 15 parts, Herba Blumeae Lacerae 10 parts, Radix Maesae Japonicae 15 parts, Rabdosia rubescens 30 parts, Herba Glechomae 15 parts, Radix et Rhizoma Iridis Sanguineae 10 parts, Radix seu Herba Pegaeophytonis Scapiflori 3 parts, Herba Polygalae Japonicae 15 parts, Herba suadeae glaucae 6 parts, Rhizoma Imperatae 10 parts, the Fructus Kochiae 10 parts, Diplazium lanceum (Thunb) 15 parts, Folium Sauropi 10 parts, Herba Agrimoniae 5 parts, Herba Euphorbiae Humifusae 10 parts, Cacumen Tamaricis 3 parts, Radix Cynanchi Atrati 5 parts, Caulis Bambusae In Taenia 5 parts, Semen Cassiae 10 parts, 3 parts, Pericarpium Zanthoxyli, Herba Lycopodii 5 parts, Ophicalcitum 5 parts, Herba abutili indici 10 parts, Flos Celosiae Cristatae 6 parts, Celastrus gemmatus Loes. 10 parts and 3 parts, Pericarpium Citri Reticulatae Viride.
More preferably, described medicament can be tablet, dispersible tablet, lotion or decoction.
In order to understand the present invention better, with reference to " Chinese medicine voluminous dictionary " second edition (Shanghai science tech publishing house, 2005), the explanation of some crude drug used in the present invention sees the following form:
Generally acknowledged that " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " compound recipe use ", " compound compatibility medication is as used military forces " are the traditional Chinese medical science the most effective most scientific several large advantages at present, wherein " compound compatibility medication is as used military forces " is the original theory of Chinese medicine of very science.The tight compatibility that in traditional Chinese medical science prescription, each medicine is all linked with one another as arrayed troops for battle is that it is better than the effective means of Western medicine formula.Tcm prescription theory is thought, each prescription, not only need to select the appropriate compatibility of suitable medicament according to etiology and pathogenesis, also should meet the basic structure of prescription simultaneously, the i.e. prescription compatibility theory of " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make " is exactly that it is based upon the scientific matching on the comprehensive judgement basis of disease pathogenesis.In medical side by too many levels, Mutiple Targets Integrate adjustment biological mechanism, can to obtain than Western medicine more lastingly, the more therapeutic effect that has no side effect of green natural, and this curative effect be based upon the above-mentioned traditional Chinese medical science tradition original theory accurate instruction on, the present invention just have followed this principle.
For compositions of the present invention, according to the prescription compatibility theory of " monarch, minister, help, make ", Herba Anagallidis Arvensis, Folium Rhododendri Mucronati, Radix seu herba Heteropogonis Contorti, Semen Ciceris Arietini, Herba Commelinae Diffusae are monarch drug; When medicine, Arillus Longan, Radix Stephaniae hemandifoliae, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Averrhoae Carambolae, fernleaf hedge bamboo, the Radix Pulsatillae, Herba Iresines Herbstii, Herba Blumeae Lacerae, Radix Maesae Japonicae are ministerial drug; Rabdosia rubescens, Herba Glechomae, Radix et Rhizoma Iridis Sanguineae, Radix seu Herba Pegaeophytonis Scapiflori, Herba Polygalae Japonicae, Herba suadeae glaucae, Rhizoma Imperatae, the Fructus Kochiae, Diplazium lanceum (Thunb), Folium Sauropi, Herba Agrimoniae, Herba Euphorbiae Humifusae, Cacumen Tamaricis, Radix Cynanchi Atrati, Caulis Bambusae In Taenia are adjuvant drug; Semen Cassiae, Pericarpium Zanthoxyli, Herba Lycopodii, Ophicalcitum, Herba abutili indici, Flos Celosiae Cristatae, Celastrus gemmatus Loes. and Pericarpium Citri Reticulatae Viride are for making medicine.Whole compositions of the medicament for the treatment of alopecia totalis of the present invention and alopecia universalis are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment lotion of the present invention
Take Herba Anagallidis Arvensis 10 grams, Folium Rhododendri Mucronati 10 grams, Radix seu herba Heteropogonis Contorti 15 grams, Semen Ciceris Arietini 10 grams, Herba Commelinae Diffusae 10 grams, when medicine 6 grams, Arillus Longan 10 grams, Radix Stephaniae hemandifoliae 10 grams, Ilex purpurea Hassk.[I.chinensis Sims 15 grams, Fructus Averrhoae Carambolae 20 grams, fernleaf hedge bamboo 10 grams, the Radix Pulsatillae 10 grams, Herba Iresines Herbstii 15 grams, Herba Blumeae Lacerae 10 grams, Radix Maesae Japonicae 15 grams, Rabdosia rubescens 30 grams, Herba Glechomae 15 grams, Radix et Rhizoma Iridis Sanguineae 10 grams, Radix seu Herba Pegaeophytonis Scapiflori 3 grams, Herba Polygalae Japonicae 15 grams, Herba suadeae glaucae 6 grams, Rhizoma Imperatae 10 grams, the Fructus Kochiae 10 grams, Diplazium lanceum (Thunb) 15 grams, Folium Sauropi 10 grams, Herba Agrimoniae 5 grams, Herba Euphorbiae Humifusae 10 grams, Cacumen Tamaricis 3 grams, Radix Cynanchi Atrati 5 grams, Caulis Bambusae In Taenia 5 grams, Semen Cassiae 10 grams, 3 grams, Pericarpium Zanthoxyli, Herba Lycopodii 5 grams, Ophicalcitum 5 grams, Herba abutili indici 10 grams, Flos Celosiae Cristatae 6 grams, Celastrus gemmatus Loes. 10 grams and 3 grams, Pericarpium Citri Reticulatae Viride, add 1000 milliliters, water, heat 3 hours at 100 DEG C in the flask that condensing tube is housed, filter, filtrate is cooled to room temperature, be lotion of the present invention.
Experimental example
Physical data
Treatment alopecia totalis, alopecia universalis 50 example, wherein alopecia totalis 20 example, alopecia universalis 30 example, man 25 example, female 25 example, age 29-56 year, the shortest course of disease 2 months, the longest course of disease 3 years, course of disease person 20 example within 1 year and 1 year, the course of disease is greater than 1 year person 30 example.
Inclusion criteria alopecia totalis: head hair all comes off, or the patients with alopecia areata having alopecia totalis medical history.Alopecia universalis: the patients with alopecia areata that eyebrow, hair, armpit hair, eyelashes, pubes come off.
Exclusion standard (1) health check-up has pulmonary tuberculosis, diabetes, hypertension, gastric ulcer, psychosis; (2) pseudopelade; (3) toxic and physiologic alopecia, as alopecia medicamentosa (using hyperthyroidism medicine, immunosuppressant and hyperthyroidism hypothyroidism, puerperal alopecia); (4) alopecia traumatica, as hair dyeing, curly hair, chemical boiling hot, trichotillomania.
The lotion prepared in embodiment is used to treat.Treat 1 every day.When treating, take Herba Anagallidis Arvensis 10 grams, Folium Rhododendri Mucronati 10 grams, Radix seu herba Heteropogonis Contorti 15 grams, Semen Ciceris Arietini 10 grams, Herba Commelinae Diffusae 10 grams, when medicine 6 grams, Arillus Longan 10 grams, Radix Stephaniae hemandifoliae 10 grams, Ilex purpurea Hassk.[I.chinensis Sims 15 grams, Fructus Averrhoae Carambolae 20 grams, fernleaf hedge bamboo 10 grams, the Radix Pulsatillae 10 grams, Herba Iresines Herbstii 15 grams, Herba Blumeae Lacerae 10 grams, Radix Maesae Japonicae 15 grams, Rabdosia rubescens 30 grams, Herba Glechomae 15 grams, Radix et Rhizoma Iridis Sanguineae 10 grams, Radix seu Herba Pegaeophytonis Scapiflori 3 grams, Herba Polygalae Japonicae 15 grams, Herba suadeae glaucae 6 grams, Rhizoma Imperatae 10 grams, the Fructus Kochiae 10 grams, Diplazium lanceum (Thunb) 15 grams, Folium Sauropi 10 grams, Herba Agrimoniae 5 grams, Herba Euphorbiae Humifusae 10 grams, Cacumen Tamaricis 3 grams, Radix Cynanchi Atrati 5 grams, Caulis Bambusae In Taenia 5 grams, Semen Cassiae 10 grams, 3 grams, Pericarpium Zanthoxyli, Herba Lycopodii 5 grams, Ophicalcitum 5 grams, Herba abutili indici 10 grams, Flos Celosiae Cristatae 6 grams, Celastrus gemmatus Loes. 10 grams and 3 grams, Pericarpium Citri Reticulatae Viride, add 1000 milliliters, water, heat 3 hours at 100 DEG C in the flask that condensing tube is housed, filter, filtrate is cooled to room temperature, then towel dipping is used, the wiping patient crown repeatedly, till the conscious skin of patient has heating sense.Continuous treatment 2 months.
Efficacy assessment standard
Recovery from illness: hair recovers completely or recovers more than 95%; Effective: hair recovers 95%-70%; Take a turn for the better: hair recovers at 70%-20%, eyebrow recovers no longer to come off; Invalid: without new piliation, hair recovers 20% or following.
The results are shown in following table
| Number of cases | Recovery from illness | Effective | Take a turn for the better | Invalid | |
| Alopecia totalis | 20 | 16 | 4 | 0 | 0 |
| Alopecia universalis | 30 | 23 | 6 | 1 | 0 |
Model case
High certain, 41 years old, female, enterprise personnel, accepted for medical treatment on April 26th, 2013, all coming off, meeting exclusion standard through inquiry through observing patients head's hair.The lotion prepared in embodiment is used to treat, the same experimental example of Therapeutic Method.Wiping every day once, is treated 2 months continuously.Patients head has grown new sending out, and hair quality black, head has not had the position of not long hair.Observe 3 months after the treatment, find that the natural on-off cycles of hair growth of patient is good, grew the basal part of the ear.
Grandson, 38 years old, female, street clerical worker, accepted for medical treatment on May 12nd, 2013, through observing patients head's top head falling out, being formed and being commonly called as " Mediterranean " hair style.Exclusion standard is met through inquiry.The lotion prepared in embodiment is used to treat, the same experimental example of Therapeutic Method.Wiping every day once, is treated 2 months continuously.Patients head top has grown new sending out, hair quality black.Observe 3 months after the treatment, find that the natural on-off cycles of hair growth of patient is good, top hair has not seen the obvious difference with other positions.
Wu so-and-so, man, 50 years old, peasant, accepted for medical treatment on June 9th, 2013, all coming off, meeting exclusion standard through inquiry through observing patients head hair.The lotion prepared in embodiment is used to treat, the same experimental example of Therapeutic Method.Wiping every day once, is treated 2 months continuously.Patients head has grown new sending out, and hair quality black, head has not had the position of not long hair.Observe 3 months after the treatment, find that the natural on-off cycles of hair growth of patient is good, grew the basal part of the ear.
Claims (1)
1. treat the medicament of alopecia totalis and alopecia universalis for one kind, it is characterized in that, it is made up of the material of following weight proportioning: Herba Anagallidis Arvensis 10 parts, Folium Rhododendri Mucronati 10 parts, Radix seu herba Heteropogonis Contorti 15 parts, Semen Ciceris Arietini 10 parts, Herba Commelinae Diffusae 10 parts, when medicine 6 parts, Arillus Longan 10 parts, Radix Stephaniae hemandifoliae 10 parts, Ilex purpurea Hassk.[I.chinensis Sims 15 parts, Fructus Averrhoae Carambolae 20 parts, fernleaf hedge bamboo 10 parts, the Radix Pulsatillae 10 parts, Herba Iresines Herbstii 15 parts, Herba Blumeae Lacerae 10 parts, Radix Maesae Japonicae 15 parts, Rabdosia rubescens 30 parts, Herba Glechomae 15 parts, Radix et Rhizoma Iridis Sanguineae 10 parts, Radix seu Herba Pegaeophytonis Scapiflori 3 parts, Herba Polygalae Japonicae 15 parts, Herba suadeae glaucae 6 parts, Rhizoma Imperatae 10 parts, the Fructus Kochiae 10 parts, Diplazium lanceum (Thunb) 15 parts, Folium Sauropi 10 parts, Herba Agrimoniae 5 parts, Herba Euphorbiae Humifusae 10 parts, Cacumen Tamaricis 3 parts, Radix Cynanchi Atrati 5 parts, Caulis Bambusae In Taenia 5 parts, Semen Cassiae 10 parts, 3 parts, Pericarpium Zanthoxyli, Herba Lycopodii 5 parts, Ophicalcitum 5 parts, Herba abutili indici 10 parts, Flos Celosiae Cristatae 6 parts, Celastrus gemmatus Loes. 10 parts and 3 parts, Pericarpium Citri Reticulatae Viride.
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Effective date of registration: 20160330 Address after: Hospital pharmacy Rencheng District No. 127 Jining City, Shandong province 272000 Mu Ge Lu in Rencheng District of Jining City Applicant after: Zhang Fangyuan Address before: 100026, Daxing District Zhongguancun science and Technology Park, Daxing pharmaceutical industry base, Tianhe West Road, No. 18, Beijing Applicant before: Jiang Xiaoyun |
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