CN104940889B - Traditional Chinese medicine preparation for patients with internal medicine neurosis - Google Patents
Traditional Chinese medicine preparation for patients with internal medicine neurosis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for patients with medical neurosis, which is prepared from the following raw materials in parts by weight: 7-15 parts of vinegar tortoise plastron, 3-10 parts of ginseng, 25-30 parts of arillus longan, 7-9 parts of fried jujube kernel, 16-25 parts of rhizoma acori graminei, 15-25 parts of polygala tenuifolia, 3-5 parts of akebia stem, 7-15 parts of rush, 1-2 parts of raw liquorice, 3-5 parts of fructus cannabis, 25-35 parts of poria cocos, 8-15 parts of ginger, 5-9 parts of coptis chinensis, 7-13 parts of concha haliotidis and 5-9 parts of vine of multiflower knotweed. The Chinese medicinal preparation has the advantages of good treatment effect, high reliability, wide adaptability and no toxic or side effect on patients with the internal neurosis.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of Chinese medicine preparation for internal medicine Patients with Neurosis.
Background technology
Neurosis refers to one kind based on phrenoblabia caused by many factors such as society, environment, psychology, physiology
Disease.It is mainly shown as the decline of cerebration ability, worry, anxiety, anxiety, depression, terror, obsessive symptoms, depressive symptom, divides
From symptom, conversion symptom or various Somatic discomfort senses.Belong to the diseases scopes such as traditional Chinese medicine melancholia, demented, insomnia, hysteria.In recent years
Morbidity increases year by year, and since the etiology and pathogenesis of the disease is complicated, extent of disease is wider, and clinical manifestation is changeable, more than Western medicine side effect and
Unsatisfactory curative effect brings certain difficulty to clinical diagnosis and treatment.Neurosis is the illness of the more difficult pool of Neurology, at present both at home and abroad
Generally use control method be using calm and medicine against depressive disorders, take these drugs not only the state of an illness be difficult to control curative effect compared with
Difference, and toxic side effect and some adverse reactions are will produce, new body and mind sufferings are caused to patient.
Chinese patent CN103599398A disclose it is a kind for the treatment of the Chinese medicine preparation of neurosis, and specifically disclose using from
The following heavy part composition of drug：4-12 grams of rhizoma anemarrhenae, 7-13 grams of Radix Polygalae, 3-10 grams of Rhizoma Gastrodiae, 14-23 grams of arillus longan, Polygonum multiflower knotweed 25-32
Gram, 9-15 grams of jujube kernel, 3-6 grams of kuh-seng, 3-5 grams of the coptis, 2-10 grams of root of Aucklandia lappa Decne, 3-6 grams of the fruit of Chinese wolfberry, 1-5 grams of Chinese cassia tree, rhizoma atractylodis macrocephalae 5-15
Gram, it is processed by above-mentioned Chinese medicine and weight.
A kind of Chinese medicine preparations for treating neurosis of Chinese patent CN1562105A, it is characterised in that by following drug weight part
Composition：8~12 grams of rhizoma anemarrhenae, 7~13 grams of Radix Polygalae, 6~10 grams of Rhizoma Gastrodiae, 28~35 grams of arillus longan, 25~32 grams of Polygonum multiflower knotweed, jujube kernel 9
~15 grams, 6~12 grams of kuh-seng, 6~10 grams of the coptis, 0~10 gram of root of Aucklandia lappa Decne, 6~12 grams of the fruit of Chinese wolfberry, 0~10 gram of Chinese cassia tree, Rhizoma Atractylodis Macrocephalae 10~
15 grams, 8~15 grams of Fructus Corni, 0~10 gram of radix rehmanniae preparata.
A kind of Chinese medicine preparations for treating neurosis of Chinese patent CN102225186A, the drug that the present invention treats neurosis are
Medicament made of the raw material matched following weight parts：20-40 parts of vinegar tortoiseshell, 3-10 parts of ginseng, 10-20 parts of arillus longan, lily
8-12 parts of 15-25 parts, 15-25 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 8-12 parts of grass-leaved sweetflag, 10-20 parts of Radix Polygalae and Radix Curcumae.
But the Chinese medicine preparation generally existing therapeutic effect of existing treatment internal medicine neurosis is poor, reliability is low, adapts to
The problems such as property is poor.
Invention content
The above problem existing for Chinese medicine preparation for existing treatment internal medicine neurosis, the object of the present invention is to provide one kind
Therapeutic effect is preferable, and reliability is higher, and adaptability is wider, and the pure Chinese medicinal preparation for the treatment nerve having no toxic side effect.
The technical scheme is that the drug that the present invention treats internal medicine neurosis is the raw material matched by following weight parts
Manufactured medicament：
7-15 parts of vinegar tortoiseshell, 3-10 parts of ginseng, 25-30 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 16-25 parts of grass-leaved sweetflag, Radix Polygalae
15-25 parts, 3-5 parts of akebi, 7-15 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, 25-35 parts of Poria cocos, ginger 8-15
5-9 parts part, 5-9 parts of the coptis, 7-13 parts of the shell of seaear of fleece-flower root rattan.
Above-mentioned each component preferred content be 8-12 parts of vinegar tortoiseshell, 5-9 parts of ginseng, 25-28 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE,
20-23 parts of grass-leaved sweetflag, 20-25 parts of Radix Polygalae, 3-5 parts of akebi, 10-12 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, Fu
5-7 parts 30-35 parts of Siberian cocklebur, 10-15 parts of ginger, 5-7 parts of the coptis, 9-11 parts of the shell of seaear of fleece-flower root rattan.
Above-mentioned each component preferred content be 9-10 parts of vinegar tortoiseshell, 7-9 parts of ginseng, 26-28 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE,
20-23 parts of grass-leaved sweetflag, 23-25 parts of Radix Polygalae, 3-5 parts of akebi, 10-12 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, Fu
5-7 parts 30-35 parts of Siberian cocklebur, 10-15 parts of ginger, 5-7 parts of the coptis, 9-11 parts of the shell of seaear of fleece-flower root rattan.
Above-mentioned each component preferred content is 9 parts of vinegar tortoiseshell, 8 parts of ginseng, 27 parts of arillus longan, 8 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, grass-leaved sweetflag 23
Part, 23 parts of Radix Polygalae, 3 parts of akebi, 10 parts of rush, 1 part of licorice, 5 parts of fructus cannabis, 33 parts of Poria cocos, 13 parts of ginger, 6 parts of the coptis,
11 parts of the shell of seaear, 7 parts of fleece-flower root rattan.
The preparations such as graininess can be made in the Chinese medicine preparation for the treatment of internal medicine neurosis provided by the present invention, and preparation method is adopted
With existing conventional method.
The present invention is improved innovation on the basis of Chinese patent CN102225186A, by the arduous examination of scientific research personnel
It testing, we finally found that the Chinese medicine preparation for the treatment of internal medicine neurosis provided by the present invention, and that there are therapeutic effects is good, and reliability is high,
Cure rate is high, and remarkable advantages are extensively waited using crowd.
Specific implementation mode
Embodiment 1
7 parts of vinegar tortoiseshell, 3 parts of ginseng, 25 parts of arillus longan, 7 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 16 parts of grass-leaved sweetflag, 15 parts of Radix Polygalae, 3 parts of akebi, lamp
7 parts of heart grass, 1 part of licorice, 3 parts of fructus cannabis, 25 parts of Poria cocos, 8 parts of ginger, 5 parts of the coptis, 7 parts of the shell of seaear, 5 parts of fleece-flower root rattan.
Embodiment 2
15 parts of vinegar tortoiseshell, 10 parts of ginseng, 30 parts of arillus longan, 9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 25 parts of grass-leaved sweetflag, 25 parts of Radix Polygalae, 5 parts of akebi,
13 parts of 15 parts of rush, 2 parts of licorice, 5 parts of fructus cannabis, 35 parts of Poria cocos, 15 parts of ginger, 9 parts of the coptis, shell of seaear fleece-flower root rattans 9
Part.
Embodiment 3
10 parts of vinegar tortoiseshell, 5 parts of ginseng, 27 parts of arillus longan, 8 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 20 parts of grass-leaved sweetflag, 20 parts of Radix Polygalae, 4 parts of akebi,
10 parts of 10 parts of rush, 1 part of licorice, 3 parts of fructus cannabis, 30 parts of Poria cocos, 10 parts of ginger, 6 parts of the coptis, shell of seaear fleece-flower root rattans 8
Part.
Embodiment 4
9 parts of vinegar tortoiseshell, 8 parts of ginseng, 27 parts of arillus longan, 8 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 23 parts of grass-leaved sweetflag, 23 parts of Radix Polygalae, 3 parts of akebi, lamp
10 parts of heart grass, 1 part of licorice, 5 parts of fructus cannabis, 33 parts of Poria cocos, 13 parts of ginger, 6 parts of the coptis, 11 parts of the shell of seaear, 7 parts of fleece-flower root rattan.
Comparative example 1
In addition to not having the vine of multiflower knotweed, remaining is the same as embodiment 1.
Comparative example 2
In addition to not having the shell of seaear, remaining is the same as embodiment 1.
Comparative example 3
In addition to not having fructus cannabis, remaining is the same as embodiment 1.
Comparative example 4
In addition to not having grass-leaved sweetflag, remaining is the same as embodiment 1.
Comparative example 5
In addition to shell of seaear content is 6 parts, remaining is the same as embodiment 1.
Comparative example 6
In addition to shell of seaear content is 14 parts, remaining is the same as embodiment 1.
One, case selection standard
(1) diagnostic techniques
1, Western medicine diagnostic criteria
(1) symptom standard, it is 1 at least following：1. frightened；2. forcing；3. panic attack；4. anxiety；5. body shape or
Symptom；6. somzatization disease；7. hypochondriasis symptom；8. neurasthenia symptom.
(2) disease journey standard meets symptom standard at least three moon.
(3) serious standard, the impaired mental disease amount of social function, promotes its active to seek medical advice.
2, tcm diagnosis standard
(1) symptom standard：Easily probably have palpitation, irritable emotion, feel restless, insomnia and dreamful sleep, depressed emotion, suspicious worry too much, is smart
Refreshing nervous, kind sigh, distending pain in the chest and hypochondrium, spiritlessness and weakness, headache and dizzy, burnout are mostly sleeping, forgetful indifferent.
(2) differential diagnosis in tcm standard
1. the insufficiency of heart and spleen：Insomnia and dreamful sleep, lustreless complexion, lassitude hypodynamia, loss of appetite, dizzy forgetful, lassitude, pale tongue
Tongue is white, and arteries and veins is thin and delicate.
2. the heart and gallbladder deficiency of vital energy：Palpitaition is timid, susceptible to fright and fear, suspicious kind worry, absent-minded, irritable emotion, pale tongue with white fur, arteries and veins is thin
It is weak；
3. fire excess from yin deficiency：Anxious, restlessness of asrhenia type and insomnia, the tired forgetful, dizziness and tinnitus of god, dysphoria in chestpalms-soles, soreness and weakness of waist and knees, tongue are red
It is few
Tongue, thready rapid pulse；
4. mental disorder pent-up mental depression, mind are dull-witted, giddy bored, automatic speaking, greasy fur on tongue, wiry and rolling pulse.
(2) case standard is tested
1, it is included in case standard
(1) doctor trained in Western medicine diagnosis meets：Meet fear, anxiety, neurasthenia diagnostic symptom 3 months or more；
(2) tcm diagnosis meets：Tcm diagnosis meets the insufficiency of heart and spleen, the heart and gallbladder deficiency of vital energy, fire excess from yin deficiency or mental disorder pent-up person.2、
Excluded cases standard
Exclude organic mental disorders；Psychoactive drug substance and non-addictive substance caused by mental disorder；Various psychotic diseases
Obstacle, such as schizophrenia, paranoid disorder, mood disorder etc..
Two, therapy
Random grouping own control comparison method is taken, the pretherapy and post-treatment symptom of patient, sign and results change are compared.
1, treatment group every group 50 take treatment neurological disease Gilles de la Tourette's syndrome and drug prepared by embodiment 1-4,6 tablets each time,
3 times a day.
2, control group every group 50 take treatment neurological disease Gilles de la Tourette's syndrome and drug and Western medicine prepared by comparative example 1-6
Common drug, 6 tablets each time, 3 times a day.
Three, parameters for observation on effect
1, the mood, mind of patient, language, behavior, the functions such as sleep；
2, tcm symptom, tongue picture, pulse condition.
Four, curative effect judging standard
1, it is almost recovered：Symptom after taking medicine disappears, and 2 years again without repeatedly；
2, effective：Medication control, 1 year or more again without repeatedly；
3, effectively：Symptom is reduced, and is mitigated；
4, invalid：Symptom is without substantially changeing.
Five, treatment results
Table 1
By embodiment 1-4 it can be seen from the data in table 1 comparative example 1- is substantially better than in terms of the effect for the treatment of neurosis
6 and Western medicine group therapeutic effect, in conjunction with the embodiments 1-4 and comparative example 1-6 and table 1 can obtain, each component content and group
Final therapeutic effect is had a significant impact at the adjustment of ingredient.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair
Change, equivalent replacement, improvement etc., be all included in the scope of protection of the present invention.
Claims (4)
1. a kind of Chinese medicine preparation for internal medicine Patients with Neurosis, which is characterized in that the raw material matched by following weight parts forms：
7-15 parts of vinegar tortoiseshell, 3-10 parts of ginseng, 25-30 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 16-25 parts of grass-leaved sweetflag, 15-25 parts of Radix Polygalae,
3-5 parts of akebi, 7-15 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, 25-35 parts of Poria cocos, 8-15 parts of ginger, coptis 5-9
5-9 parts part, 7-13 parts of the shell of seaear of fleece-flower root rattan.
2. the Chinese medicine preparation according to claim 1 for internal medicine Patients with Neurosis, which is characterized in that by following weight parts
The raw material of proportioning forms：8-12 parts of vinegar tortoiseshell, 5-9 parts of ginseng, 25-28 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, grass-leaved sweetflag 20-23
Part, 20-25 parts of Radix Polygalae, 3-5 parts of akebi, 10-12 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, 30-35 parts of Poria cocos, life
5-7 parts 10-15 parts of ginger, 5-7 parts of the coptis, 9-11 parts of the shell of seaear of fleece-flower root rattan.
3. the Chinese medicine preparation according to claim 2 for internal medicine Patients with Neurosis, which is characterized in that by following weight parts
The raw material of proportioning forms：9-10 parts of vinegar tortoiseshell, 7-9 parts of ginseng, 26-28 parts of arillus longan, 7-9 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, grass-leaved sweetflag 20-23
Part, 23-25 parts of Radix Polygalae, 3-5 parts of akebi, 10-12 parts of rush, 1-2 parts of licorice, 3-5 parts of fructus cannabis, 30-35 parts of Poria cocos, life
5-7 parts 10-15 parts of ginger, 5-7 parts of the coptis, 9-11 parts of the shell of seaear of fleece-flower root rattan.
4. the Chinese medicine preparation for internal medicine Patients with Neurosis according to one of claim 1-3, which is characterized in that by
The raw material composition of following weight parts proportioning：It is 9 parts of vinegar tortoiseshell, 8 parts of ginseng, 27 parts of arillus longan, 8 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 23 parts of grass-leaved sweetflag, remote
23 parts of will, 3 parts of akebi, 10 parts of rush, 1 part of licorice, 5 parts of fructus cannabis, 33 parts of Poria cocos, 13 parts of ginger, 6 parts of the coptis, Shi Jue
Bright 7 parts of 11 parts of fleece-flower root rattans.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102225186A (en) * | 2011-06-27 | 2011-10-26 | 史建钢 | Medicine for treating neurosis and preparation method thereof |
| CN104324347A (en) * | 2014-11-13 | 2015-02-04 | 山东中大药业有限公司 | Traditional Chinese medicine composition for treating insomnia caused by insufficiency of heart and spleen |
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2015
- 2015-07-27 CN CN201510447845.XA patent/CN104940889B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102225186A (en) * | 2011-06-27 | 2011-10-26 | 史建钢 | Medicine for treating neurosis and preparation method thereof |
| CN104324347A (en) * | 2014-11-13 | 2015-02-04 | 山东中大药业有限公司 | Traditional Chinese medicine composition for treating insomnia caused by insufficiency of heart and spleen |
Non-Patent Citations (2)
| Title |
|---|
| 中西医结合治疗广泛性焦虑症临床研究;王任昌等;《实用中医药杂志》;20130731;第29卷(第7期);563－564 * |
| 归脾汤治疗心脾两虚型郁病30例;李光英;《中国中医药现代远程教育》;20131031;第11卷(第19期);35－36 * |
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