CN103859418A - Anthocyanin-containing composition and application thereof - Google Patents
Anthocyanin-containing composition and application thereof Download PDFInfo
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- CN103859418A CN103859418A CN201410087697.0A CN201410087697A CN103859418A CN 103859418 A CN103859418 A CN 103859418A CN 201410087697 A CN201410087697 A CN 201410087697A CN 103859418 A CN103859418 A CN 103859418A
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- anthocyanidin
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- anthocyanin
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- 239000000203 mixture Substances 0.000 title claims abstract description 50
- 235000010208 anthocyanin Nutrition 0.000 title abstract 8
- 229930002877 anthocyanin Natural products 0.000 title abstract 8
- 239000004410 anthocyanin Substances 0.000 title abstract 8
- 150000004636 anthocyanins Chemical class 0.000 title abstract 8
- 235000013709 carrot oil Nutrition 0.000 claims abstract description 9
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- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 6
- 239000008107 starch Substances 0.000 claims abstract description 6
- 229930014669 anthocyanidin Natural products 0.000 claims description 64
- 150000001452 anthocyanidin derivatives Chemical class 0.000 claims description 64
- 235000008758 anthocyanidins Nutrition 0.000 claims description 64
- 239000002775 capsule Substances 0.000 claims description 12
- 239000007901 soft capsule Substances 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 9
- 239000008187 granular material Substances 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
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- 230000004438 eyesight Effects 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
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- 230000001737 promoting effect Effects 0.000 abstract 1
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- MSTNYGQPCMXVAQ-KIYNQFGBSA-N 5,6,7,8-tetrahydrofolic acid Chemical compound N1C=2C(=O)NC(N)=NC=2NCC1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 MSTNYGQPCMXVAQ-KIYNQFGBSA-N 0.000 description 1
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- 206010010741 Conjunctivitis Diseases 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 235000005135 Micromeria juliana Nutrition 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
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- 208000025865 Ulcer Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- CGLXTBACLXZPED-UHFFFAOYSA-N [4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-yl] dihydrogen phosphate Chemical compound Cc1ncc(CO)c(CN)c1OP(O)(O)=O CGLXTBACLXZPED-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
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- AEMOLEFTQBMNLQ-BKBMJHBISA-N alpha-D-galacturonic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-BKBMJHBISA-N 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000007963 capsule composition Substances 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
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- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
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- 238000005507 spraying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
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- 230000000007 visual effect Effects 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an anthocyanin-containing composition and an application thereof. The anthocyanin-containing composition is composed of following ingredients in parts by weight: 25-50 parts of anthocyanin, 10-20 parts of carrot oil, 8-16 parts of Vc, 3-6 parts of VB2, 5-10 parts of VB6 and 49-98 parts of soluble starch; or the anthocyanin-containing composition is composed of following ingredients in parts by weight: 25-50 parts of the anthocyanin, 10-20 parts of the carrot oil, 8-16 parts of the Vc, 3-6 parts of the VB2, 5-10 parts of the VB6 and 49-98 parts of edible oil. The anthocyanin-containing composition has the beneficial effects that the anthocyanin-containing composition has the effects of protecting eyes, removing over-fatigues of human eyes caused by a computer, improving the function of the eyes and promoting the re-synthesis effect of erythrolabe so that the eyesight of people is improved and people can recover from fatigue.
Description
Technical field
The invention belongs to anthocyanidin development technique field, particularly relate to one containing anthocyanidin composition, and the application of said composition.
Background technology
Anthocyanidin is a kind of food additives of being used widely in multiple industry, the multiple products for civilian use such as diet, daily-use chemical industry, medicine.Can promote the synthetic again of erythrolabe on retina, strengthen human eyesight.
Carrot oil: stabilizing agent and antioxidant, improve the powdery excipient in its dissolubility dispersion and water;
VC: promote that folic acid becomes tetrahydrofolic acid, be conducive to nucleic acid synthetic, promote erythrocytic generation, can also make Fe
3+be reduced to Fe
2+thereby, be easy to absorb, be also of value to the generation of cell, participate in the generation of collagen.Have neutralize a toxin, enhancing antibody generate effect, can strengthen the detoxication of body.
VB
2: participate in many redox friends in body and close and sugar, protein and fatty metabolism, maintain emmetropia visual performance.Be used for the treatment of aviboflavinosis, conjunctivitis, trophic ulcer, nutrition of whole body obstacle and other diseases.
VB
6: after absorption of human body, forming in vivo phosphopyridoxal pyridoxal phosphate and the phosphopyridoxamine of tool physiologically active, is nervous centralis inhibitory transmitter, plays a part to suppress or reconcile excitatory state, gathers around anti-spasm and reduces the abnormal usefulness of electroencephalogram.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of containing anthocyanidin composition and in the application of preparing in granule, tablet, capsule, soft capsule and drink oral liquid.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of containing anthocyanidin composition, composed of the following components:
Anthocyanidin 25~50 weight portions; Carrot oil 10~20 weight portions; Vc8~16 weight portion; VB
23~6 weight portions; VB
65~10 weight portions; Soluble starch 49~98 weight portions;
Or, should be composed of the following components containing anthocyanidin composition:
Anthocyanidin 25~50 weight portions; Carrot oil 10~20 weight portions; Vc8~16 weight; VB
23~6 weight portions; VB
65~10 weight portions; Edible oil 49~98 weight portions.
As above containing anthocyanidin composition, preferred, anthocyanidin 30~40 weight portions.
As above containing anthocyanidin composition, preferred, carrot oil 12~16 weight portions.
As above containing anthocyanidin composition, preferred, Vc10~12 weight portion.
As above containing anthocyanidin composition, preferred, VB
24~5 weight portions.
As above containing anthocyanidin composition, preferred, VB
66~8 weight portions.
As above containing anthocyanidin composition, preferred, soluble starch 60~80 weight portions.
As above containing anthocyanidin composition, preferred, VB
65~10 weight portion edible oil 60~80 weight portions.
The anthocyanidin composition that contains as above is in the application of preparing in granule, tablet, capsule, soft capsule and drink oral liquid.
The anthocyanidin that the present invention's anthocyanidin used preferably extracts from wild berry cowberry, blackcurrant, elder, black rice, Mulberry fruit, purple wild cabbage, roselle, celestial being's jujube, black fruit lyceum berry, grape pip, Grape Skin.
The invention has the beneficial effects as follows: the composition consisting of the rational proportioning of each component can asthenopia relief, to eye health, remove computer overtired to human eye, improve eye function and promote to look the synthesis again of haematochrome, thereby the eyesight that strengthens people, sets up.
Product of the present invention is taking anthocyanidin as main navy blue, sweet and sour, slightly sticking pectic substance, and savory and extract the refining product forming by modern ultralow temperature.Wherein the scale dimension of content 13% left and right, fructose and the glucose of sugar is held in 1:1.2 left and right, and organic acid maintains 1% left and right, and organic acid is almost to exist and account for 83%-93% small part as quininic acid and malic acid taking citric acid form entirely.Vitamin C, B
2, B
6stable complex is called as antipellagra factor, and people's pellagroid and dog class black tongue disease are had to certain curative effect.The anthocyanidin extracting, the content of trace element, iron, potassium, manganese is very high, synthetic, the eyesight that strengthens people again to eye retina erythrolabe, delay cranial nerve aging, improve the function of the circulatory system, PVR that function, instinct vascular hypertension, vein tumour, hypertension and the diabetes of active oxygen of going out cause has good curative effect.
Detailed description of the invention
Below in conjunction with embodiment, principle of the present invention and feature are described, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Anthocyanidin preparation method of the present invention is as follows:
Step 1, from cowberry, in blackcurrant, elder, black rice, Mulberry fruit, purple wild cabbage, roselle, celestial being's jujube, black fruit lyceum berry, choose fresh raw material low-temperature transport and enter after factory and process at once.Grape pip, Grape Skin select dry raw material to enter factory and office's reason.
Step 2, lixiviate effective active components, with the alcohol steep raw material of 10~20wt% of 4 times of raw material weights 3 times, each 4 hours; Ultrafiltration obtains ultrafiltrate, large pore resin absorption column removal of impurities on ultrafiltrate.
Step 3, step 2 obtain material with this carry out that low temperature is concentrated, vacuum drying, pulverizing, inspection, obtain the product of anthocyanidin content >=25~95wt%.
Application process is as follows:
Produce capsule technique: after said mixture being mixed with embedding medium in GMP workshop,, inspection (every in contain anthocyanidin 0.23 ㎎~0.46 ㎎) % plastic-aluminum, packaging canned with capsule machine, check to obtain finished product.Instructions of taking: each 2 or 2 every days 3 times.
Produce soft capsule technique: in GMP workshop, by said mixture, after mixing, make carrier in edible oil, sprinkling irrigation soft capsule, inspection (in every containing anthocyanidin 0.23mg~0.46mg) plastic-aluminum, packaging, check to obtain finished product.Instructions of taking: each 2 or 2 every days 3 times.
Produce tablet technique: after said mixture being mixed with embedding medium soluble starch in GMP workshop, in tablet press machine compressing tablet, polishing, inspection (containing anthocyanidin 0.23mg~0.46mg in every) plastic-aluminum, packaging, check to obtain finished product.Instructions of taking: each 2 or 2 every days 3 times.
Drink oral liquid technique: after said mixture being mixed with in pure water in GMP workshop, stir, filling on bottle placer, inspection (in every bottle containing anthocyanidin 0.23mg~0.46mg), pack, check and to obtain finished product in emulsifier.Instructions of taking: each 1 bottle, every day 3 times.
Embodiment 1
The present embodiment is as follows containing the formula of anthocyanidin composition:
25 grams of anthocyanidin, 10 grams of carrot oils, Vc8 gram, VB
23 grams, VB
65 grams, 49 grams of soluble starches.
Measure each component by above-mentioned weight fraction another name, mix the composition that makes anthocyanidin of the present invention with mixer.
Utilize medicine comminutor/tablet press machine/capsule filling machine.The composition of the anthocyanidin of the present invention to above-mentioned acquisition carries out granulation, compressing tablet, filling capsule.Obtain 1000 bags/sheet/grain, anthocyanidin particle/sheet/capsule.
Embodiment 2
50 grams of anthocyanidin, 20 grams of carrot oils, Vc16 gram, VB
26 grams, VB
610 grams, 98 grams, soya-bean oil.
Measure each component by above-mentioned weight fraction another name, mix and make anthocyanidin capsule composition of the present invention with mixer.
Utilize medicine sprinkling irrigation encapsulating machine, the present invention of above-mentioned acquisition, containing the composition of the anthocyanidin soft capsule of spraying, is obtained to 2000 soft capsules that contain anthocyanidin.
200 testers that the sheet/capsule/soft capsule containing anthocyanidin of preparation in embodiment 1,2 is worked before computer to every day 3~6 hours test, each 2 every days 3 times.Tester's asthenopia relief rate reaches 86%.
Embodiment 3
The present embodiment is as follows containing the formula of the composition of anthocyanidin:
37.5 grams of anthocyanidin, 15 grams of carrot oils, Vc12 gram, VB
24.5 grams, VB
67.5 grams, 73.5 grams of soluble starches.
Measure each component by above-mentioned weight fraction another name, mix the composition that makes anthocyanidin of the present invention with mixer.
Utilize medicine comminutor/sheet machine machine/capsule filling machine.The composition of the anthocyanidin of the present invention to above-mentioned acquisition carries out granulation, compressing tablet, filling capsule.Obtain 1500 bags/sheet/grain, anthocyanidin particle/sheet/capsule.
Embodiment 4
37.5 grams of anthocyanidin, 15 grams of carrot oils, Vc12 gram, VB
24.5 grams, VB
67.5 grams, 73.5 grams, soya-bean oil;
Measure each component by above-mentioned weight fraction another name, mix with mixer, make the composition of anthocyanidin of the present invention.
Utilize medicine soft capsule bottle placer.The composition of the anthocyanidin of the present invention to above-mentioned acquisition carries out filling soft capsule.Obtain 1500 anthocyanidin soft capsules.
Embodiment 5
25 grams of anthocyanidin, 10 grams of carrot oils, Vc8 gram, VB
23 grams, VB
65 grams,
Measure each component by above-mentioned weight fraction another name, mix and in emulsification stirred vessel, add pure water 990ml to make the composition of anthocyanidin drink of the present invention, oral liquid with mixer.Utilize pharmaceutical oral liquid bottle placer.Anthocyanidin drink of the present invention to above-mentioned acquisition, the composition of oral liquid carry out filling.Obtain 1000ml, every 10ml anthocyanidin drink oral liquid.
200 testers that worked every day before computer 3~6 hours containing anthocyanidin drink oral liquid of preparation in embodiment 5 are tested, each 1 bottle, every day 2 times.Tester's asthenopia relief rate reaches 90%.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. containing an anthocyanidin composition, composed of the following components:
Anthocyanidin 25~50 weight portions; Carrot oil 10~20 weight portions; Vc8~16 weight portion; VB
23~6 weight portions; VB
65~10 weight portions; Soluble starch 49~98 weight portions;
Or, composed of the following components:
Anthocyanidin 25~50 weight portions; Carrot oil 10~20 weight portions; Vc8~16 weight; VB
23~6 weight portions; VB
65~10 weight portions; Edible oil 49~98 weight portions.
2. according to claim 1 containing anthocyanidin composition, it is characterized in that anthocyanidin 25~50 weight portions.
3. according to claim 1 containing anthocyanidin composition, it is characterized in that carrot oil 10~20 weight portions.
4. according to claim 1 containing anthocyanidin composition, it is characterized in that Vc8~16 weight portion.
5. according to claim 1 containing anthocyanidin composition, it is characterized in that VB
23~6 weight portions.
6. according to claim 1 containing anthocyanidin composition, it is characterized in that VB
65~10 weight portions.
According to described in claim 1-6 any one containing anthocyanidin composition, it is characterized in that soluble starch 49~weight portion.
According to described in claim 1-6 any one containing anthocyanidin composition, it is characterized in that edible oil 60~80 weight portions.
According to described in claim 1-8 any one containing anthocyanidin composition in the application of preparing in granule, tablet, capsule, soft capsule and drink oral liquid.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106136242A (en) * | 2016-08-10 | 2016-11-23 | 西安杨健药业有限公司 | A kind of formula for bowel relieving beauty treatment and preparation method thereof |
CN106360241A (en) * | 2016-11-22 | 2017-02-01 | 青岛农业大学 | Refreshing electronic game beverage modifier formula and making method and use method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101837032A (en) * | 2010-05-22 | 2010-09-22 | 通化腾龙生物科技有限公司 | Blueberry anthocyanin oral solution |
CN103300373A (en) * | 2013-06-26 | 2013-09-18 | 重庆艾视生物科技有限公司 | Lutein and procyanidine composite soft capsule and preparation method thereof |
CN103610842A (en) * | 2013-11-15 | 2014-03-05 | 天津金耀集团有限公司 | Kudzuvine root extract and grape seed extract-containing composition |
-
2014
- 2014-03-11 CN CN201410087697.0A patent/CN103859418A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101837032A (en) * | 2010-05-22 | 2010-09-22 | 通化腾龙生物科技有限公司 | Blueberry anthocyanin oral solution |
CN103300373A (en) * | 2013-06-26 | 2013-09-18 | 重庆艾视生物科技有限公司 | Lutein and procyanidine composite soft capsule and preparation method thereof |
CN103610842A (en) * | 2013-11-15 | 2014-03-05 | 天津金耀集团有限公司 | Kudzuvine root extract and grape seed extract-containing composition |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106136242A (en) * | 2016-08-10 | 2016-11-23 | 西安杨健药业有限公司 | A kind of formula for bowel relieving beauty treatment and preparation method thereof |
CN106360241A (en) * | 2016-11-22 | 2017-02-01 | 青岛农业大学 | Refreshing electronic game beverage modifier formula and making method and use method thereof |
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