CN103845468B - A kind ofly treat the bad Chinese medicine composition of involution of uterus of puerperal - Google Patents
A kind ofly treat the bad Chinese medicine composition of involution of uterus of puerperal Download PDFInfo
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- CN103845468B CN103845468B CN201410106310.1A CN201410106310A CN103845468B CN 103845468 B CN103845468 B CN 103845468B CN 201410106310 A CN201410106310 A CN 201410106310A CN 103845468 B CN103845468 B CN 103845468B
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- 241001649190 Campsis Species 0.000 claims abstract description 10
- 241000903946 Clematidis Species 0.000 claims abstract description 10
- 241000628997 Flos Species 0.000 claims abstract description 10
- 239000008280 blood Substances 0.000 abstract description 14
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- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 description 3
- 101800000989 Oxytocin Proteins 0.000 description 3
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- 208000018525 Postpartum Hemorrhage Diseases 0.000 description 3
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 description 3
- 229960001723 oxytocin Drugs 0.000 description 3
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- 208000004998 Abdominal Pain Diseases 0.000 description 1
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- 206010056254 Intrauterine infection Diseases 0.000 description 1
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Abstract
The invention discloses and a kind ofly treat the bad Chinese medicine composition that returns to the past puerperal.Involution of uterus of puerperal bad genus Chinese medicine postpartum lochiorrhea, puerperal abdonimal pain category.Its consumption gas of losing blood, cloudy Tianjin trauma, easily causes insufficiency of vital energy and blood and even virtual loss; Lochia to the greatest extent, does not easily cause blood-stasis internal-depression, disorder of QI movement.The present invention selects to have blood stasis dispersing and fresh blood promoting, tonify deficiency warms up the Chinese medicine Herba Aristolochiae in palace, Radix Clematidis Henryi, Herba jasmini polyanthi, Radix potentillae anserinae, Rhizoma nupharis pumili, Radix Rubiae yunnanensis, Flos Campsis, Cortex seu Radix Euonymi oxyphyllae, Radix Antiotrematis dunniani, and decocting becomes decoction, through clinical trial, total effective rate reaches 86.6%, is obviously better than matched group.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to and a kind ofly treat the bad Chinese medicine composition of involution of uterus of puerperal.
Technical background
The involution of uterus is bad is one commonly encountered diseases in puerperal, frequently-occurring disease.Along with the rising of cesarean delivery rate, the incidence rate of primary disease increases gradually, and primary disease is also one of inducement causing postpartum hemorrhage or late postpartum hemorrhage simultaneously.The bad lochia that shows as of involution of uterus of puerperal drenches the clean or stomachache of drop more.Modern medicine is thought, involution of uterus of puerperal is bad is part Placenta Hominis, fetal membrane is residual or Placenta Hominis attachment area infects, and makes local can not normal restoration, affects uterine contraction and to cause involution of uterus of puerperal bad.At present, be still common with Resident placenta membrane, intrauterine infection.If endometrium and pelvic infection, retroversion, tumor between uterine muscular, multiple pregnancy, uterine fibroid is organized and is relatively increased, and Placenta Hominis attachment makes uterine muscular form, structural change, Placental measurement increases, cause uterus muscle contractility weak, inner membrance vessel open section increases, and amount of bleeding is large, the bleeding time is long.Blood is the stasis of blood in uterine cavity, increases the weight of uterus and contracts bad again, increases retrograde infection.Treat mainly with antibiotic and uterine contraction agent clinically at present.Owing to using larger dose oxytocin puerperal, make uterus tetanic contraction, furthermore the oxytocin half-life is short, often makes uterus secondary contraction bad, and puerpera often occurs insufferable uterine contraction pain and refuses to continue to use.
Summary of the invention
The object of this invention is to provide and a kind ofly treat the bad Chinese medicine composition that returns to the past puerperal.Motherland's medical science thinks involution of uterus of puerperal bad genus Chinese medicine postpartum lochiorrhea, puerperal abdonimal pain category.Its consumption gas of losing blood, cloudy Tianjin trauma, easily causes insufficiency of vital energy and blood and even virtual loss; Lochia to the greatest extent, does not easily cause blood-stasis internal-depression, disorder of QI movement.The suitable blood stasis dispersing and fresh blood promoting of Chinese traditional treatment, tonify deficiency warms up palace.
The object of the invention is to be achieved through the following technical solutions, the bad Chinese medicine composition of this treatment involution of uterus of puerperal is made up of the Chinese medicine of following weight portion: Herba Aristolochiae 7-10 part, Radix Clematidis Henryi 10-15 part, Herba jasmini polyanthi 25-30 part, Radix potentillae anserinae 16-28 part, Rhizoma nupharis pumili 9-15 part, Herba Rubiae Yunnanensis 35-45 part, Flos Campsis 3-6 part, Cortex seu Radix Euonymi oxyphyllae 15-30 part, Radix Antiotrematis dunniani 9-12 part.
Preferably, Herba Aristolochiae 8.5 parts, Radix Clematidis Henryi 13 parts, Herba jasmini polyanthi 28 parts, Radix potentillae anserinae 22 parts, Rhizoma nupharis pumili 12 parts, Herba Rubiae Yunnanensis 40 parts, Flos Campsis 5 parts, Cortex seu Radix Euonymi oxyphyllae 22 parts, Radix Antiotrematis dunniani 10 parts.
Preparation method by above-mentioned Chinese medicine traditionally decocting make decoction.
Fang Zhong: Herba Aristolochiae circulation of qi promoting removing dampness, promoting blood circulation and stopping pain; Radix Clematidis Henryi promoting the circulation of QI to relieve pain, invigorate blood circulation, antiinflammatory; Herba jasmini polyanthi promoting the circulation of QI to relieve pain, to invigorate blood circulation; Radix potentillae anserinae vigorate qi and replenish the blood, invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst, dampness removing; Rhizoma nupharis pumili tonify deficiency, stomach invigorating, regulating menstruation; Herba Rubiae Yunnanensis enrich blood invigorate blood circulation, expelling wind and removing dampness, softening the hard mass removing mass; Flos Campsis blood stasis dispelling removing heat from blood; Cortex seu Radix Euonymi oxyphyllae blood circulation promoting competent silt, to stimulate the menstrual flow; Radix Antiotrematis dunniani yin nourishing tonify deficiency, heat-clearing and toxic substances removing.
Clinical data
1, physical data all cases is the court and is in hospital from year May in January, 2006 to 2009 primipara of spontaneous labor, totally 90 examples.Be divided into treatment group and matched group at random.At 23 ~ 35 years old age, full-term pregnancy, without pregnancy complication, complication and postpartum hemorrhage.Wherein treatment group 45 example, the mean age (26.30 ± 1.89) year; Matched group 45 example, the mean age (26.47 ± 1.87) year.Two groups through statistical test, there was no significant difference.
2, diagnostic criteria diagnostic criteria is drafted with reference to Ministry of Public Health programming textbook " obstetrics and gynecology ".Uterus in puerperal flat umbilicus at the bottom of the 1st Heavenly Palace, should decline every day 1-2cm later, and all decline is less than 1cm, or lochia increases, or lochia duration extension, and diagnosable is that the involution of uterus is bad.
3, Therapeutic Method treatment group: take above-mentioned Chinese medicine composition, takes Herba Aristolochiae 8.5g, Radix Clematidis Henryi 13g, Herba jasmini polyanthi 28g, Radix potentillae anserinae 22g, Rhizoma nupharis pumili 12g, Herba Rubiae Yunnanensis 40g, Flos Campsis 5g, Cortex seu Radix Euonymi oxyphyllae 22g, Radix Antiotrematis dunniani 10g.1 dose/d, decoct juice 120-150mL at every turn, take for 3 times for early, middle and late point.Matched group: oxytocin 10U, intramuscular injection, 6h or 12h is once; Or 10-20u adds the injection of liquid medium-sized vein.Two groups all with 1 week for observing treatment time, observe involution of uterus situation to evaluate curative effect.
4, efficacy assessment standard is cured: uterus to decline 1-2cm every day, and lochia vaginae amount is few or stop, the transference cures such as stomachache.Take a turn for the better: uterus decline every day is less than 1-2cm, and vaginal hemorrhage reduces, and colic symptoms alleviates.Do not heal: symptom is without improvement.
5, therapeutic outcome two groups treatment one week rear comparitive study, treatment group 45 example, wherein cures 20 examples (44.4%), 19 examples that take a turn for the better (42.2%), and do not heal 6 examples (13.3%), total effective rate 86.6%; Matched group 45 example, wherein cures 13 examples (28.9%), 15 examples that take a turn for the better (33.3%), and do not heal 17 examples (37.8%), total effective rate 62.2%.Two groups are compared, and treatment group cure rate, total effective rate are obviously better than matched group, have comparability.P＜0.05。
Detailed description of the invention
Embodiment one: take Herba Aristolochiae 8.5g, Radix Clematidis Henryi 13g, Herba jasmini polyanthi 28g, Radix potentillae anserinae 22g, Rhizoma nupharis pumili 12g, Herba Rubiae Yunnanensis 40g, Flos Campsis 5g, Cortex seu Radix Euonymi oxyphyllae 22g, Radix Antiotrematis dunniani 10g, by above-mentioned Chinese medicine decocting extracting juice, 1 dose/d, decoct juice 120-150mL at every turn, take for 3 times for early, middle and late point.
Embodiment two: take Herba Aristolochiae 10g, Radix Clematidis Henryi 15g, Herba jasmini polyanthi 25g, Radix potentillae anserinae 16g, Rhizoma nupharis pumili 15g, Herba Rubiae Yunnanensis 45g, Flos Campsis 6g, Cortex seu Radix Euonymi oxyphyllae 15g, Radix Antiotrematis dunniani 12g, by above-mentioned Chinese medicine decocting extracting juice, 1 dose/d, decoct juice 120-150mL at every turn, take for 3 times for early, middle and late point.
Embodiment three: take Herba Aristolochiae 7g, Radix Clematidis Henryi 10g, Herba jasmini polyanthi 30g, Radix potentillae anserinae 28g, Rhizoma nupharis pumili 9g, Herba Rubiae Yunnanensis 30g, Flos Campsis 3g, Cortex seu Radix Euonymi oxyphyllae 30g, Radix Antiotrematis dunniani 9g, by above-mentioned Chinese medicine decocting extracting juice, 1 dose/d, decoct juice 120-150mL at every turn, take for 3 times for early, middle and late point.
Claims (2)
1. treat the Chinese medicine composition that involution of uterus of puerperal is bad, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Aristolochiae 7-10 part, Radix Clematidis Henryi 10-15 part, Herba jasmini polyanthi 25-30 part, Radix potentillae anserinae 16-28 part, Rhizoma nupharis pumili 9-15 part, Herba Rubiae Yunnanensis 35-45 part, Flos Campsis 3-6 part, Cortex seu Radix Euonymi oxyphyllae 15-30 part, Radix Antiotrematis dunniani 9-12 part.
2. a kind ofly as claimed in claim 1 treat the bad Chinese medicine composition of involution of uterus of puerperal, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Aristolochiae 8.5 parts, Radix Clematidis Henryi 13 parts, Herba jasmini polyanthi 28 parts, Radix potentillae anserinae 22 parts, Rhizoma nupharis pumili 12 parts, Herba Rubiae Yunnanensis 40 parts, Flos Campsis 5 parts, Cortex seu Radix Euonymi oxyphyllae 22 parts, Radix Antiotrematis dunniani 10 parts.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105250905A (en) * | 2015-10-22 | 2016-01-20 | 范东梅 | Traditional Chinese medicine composition for treating postpartum uterus subinvol ution and preparation method thereof |
| CN105169295A (en) * | 2015-11-02 | 2015-12-23 | 程志娟 | Traditional Chinese medicine pills for treating puerperal uterine subinvolution and preparation method thereof |
| CN105560629A (en) * | 2015-12-29 | 2016-05-11 | 孙天虹 | Medicinal composition for treating postpartum abdominalgia with blood stasis, and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600419A (en) * | 2012-03-27 | 2012-07-25 | 高丽丽 | Chinese medicinal composition for treating chronic appendagitis, and preparation method thereof |
| CN102935211A (en) * | 2012-11-13 | 2013-02-20 | 陈维爱 | Medicine for treating undesirable involution of uterus after childbirth or abortion |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600419A (en) * | 2012-03-27 | 2012-07-25 | 高丽丽 | Chinese medicinal composition for treating chronic appendagitis, and preparation method thereof |
| CN102935211A (en) * | 2012-11-13 | 2013-02-20 | 陈维爱 | Medicine for treating undesirable involution of uterus after childbirth or abortion |
Non-Patent Citations (1)
| Title |
|---|
| 中医妇科常见病的诊治;李祥云;<<中国农村医学>>;19880131(第1期);第41-42页 * |
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