CN103829340A - Functional drink and preparation method thereof - Google Patents
Functional drink and preparation method thereof Download PDFInfo
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- CN103829340A CN103829340A CN201410079243.9A CN201410079243A CN103829340A CN 103829340 A CN103829340 A CN 103829340A CN 201410079243 A CN201410079243 A CN 201410079243A CN 103829340 A CN103829340 A CN 103829340A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention provides a functional drink comprising 5-10wt% (weight) of rhizoma polygonati, 3-5wt% of (cauterize) astragalus membranaceus, 3-8wt% of fructus hippophae extractive, 0.1-1wt% of selenium enrichment lucid ganoderma hypha powder, 1-5wt% of dendrobium officinale and 0.01-0.03wt% of epsilon-polylysine. The invention provides a preparation method of the functional drink simultaneously. According to the functional drink provided by the invention, on the one hand, four traditional Chinese medicines with immunoregulation are in compatibility of medicines with the selenium enrichment lucid ganoderma hypha powder cultured by submerged fermentation so that the functional drink has the functions of antifatigue, anti-tumor and anti-aging, and a novel way of manual selenium supplement is developed, on the other hand, each traditional Chinese medicine can be benefited with one another through proper selection of content of each traditional Chinese medicine and content of organic selenium. In addition, the functional drink provided by the invention is not added with any chemical preservative and food additive and is pure natural, stable in component, high in nutrition and good in taste.
Description
Technical field
The invention belongs to health food technology field, be specifically related to a kind of antifatigue, anti-ageing, antineoplastic drinks and preparation method thereof.
Background technology
Along with urbanization, industrialized quickening, environmental pollution is day by day serious, affects the NCDs such as cardiovascular and cerebrovascular diseases, diabetes, tumour and the burnout syndrome of health of people and sharply rises.According to the Ministry of Public Health " 2012 Chinese tumour annual report ", average 6 malignant tumours that detect per minute of hospital of China, average per minute have 5 dead because of tumour, estimate that in nearly 20~30 years, the outburst of blowout formula will appear in neoplastic disease.
60 years old above old man of China reached 1.2 hundred million, will account for the more than 20% of population to the year two thousand twenty 65 years old and above the elderly.The arrival of aging population, various geriatric diseases increase, and how to improve the aged's the general level of the health and quality of life, have become a very important social concern.Meanwhile, the enhancing of people's health care consciousness, market sharply increases health products demand anti-ageing, that improve the aspects such as immunity, and definite, the cost-effective health food of development function and medicine meet people to healthy demand, are imminent.
Selenium is one of trace element of needed by human, has important physiological function.The Keshan disease of human body, cardiovascular and cerebrovascular disease, immunity of organisms go down etc. more than 490, and to plant disease all relevant with scarce selenium, it is reported: the area of China 72% lacks selenium or poor selenium, the intake of these district Selenium In Foods every day only has 20~30ug left and right, proposes the standard of the healthy selenium intake of adult at 50~100ug far below NI of the world.The anti-cancer experiment of carrying out according to another Arizona, USA university, per day for adults is supplemented 200ug Organic Selenium, and cancer total incidence reduces by 37%, and wherein prostate cancer reduces by 63%, and colon cancer reduces by 58%, and lung cancer reduces by 46%, and cancer patient general mortality rate reduces by 50%.Expert has proposed the suggestion of " whole people mend selenium ", but the mankind cannot absorb the selenium of inorganic states, must be that organic human body could absorb through bio-transformation, think at present, to the biological transformation ratio amount of selenium high be Mycophyta, and the highest to the conversion ratio of selenium with medicinal fungi glossy ganoderma.
The method of western medical treatment tumour is the pathology for human organ and tissue at present, and first-selected is operation, radiation and chemotherapy, and the consequence that operation brings is to stimulate tumour diffusion, when radiotherapy and chemotherapy are killed cancer cell, people's immunologic function is also urged in the flue; Chinese traditional treatment tumour, from people's entirety, for pathogenic factor, adopts the methods such as Traditional Chinese Medicine Fuzheng is eliminating evil, promoting blood circulation and removing blood stasis, softening and resolving hard mass, helps human body self-organizing to manage body cell.In natural drug, many saccharide compounds can synthesize multiple glycoprotein, improve human body autoimmunity ability, astragalus polyose has the effect of inducing apoptosis of tumour cell, some luxuriant and rich with fragrance compounds, quinones, triterpene compound and phytosterin compound etc. can have direct inhibition and killing action to tumour cell, and its advantage is confirmed by clinical.
Summary of the invention
The present invention adopts biological selenium-enriched technology, has strengthened the functional of beverage, and good stability is nutritious, has opened up the new way that human body is mended selenium; Adopt biological antiseptic technology simultaneously, guarantee pure natural, reach the target useful and harmless to human body, started beverage/food corrosion-resistant new method.
The invention provides a kind of drinks, described in contain sealwort 5~10wt%, (moxibustion) Radix Astragali 3~5 wt%, Sha sour jujube berry extract 3~8 wt%, Se-rich lucid ganoderma hypha powder 0.1~1 wt%, dendrobium candidum 1~5 wt% and polylysine 0.01~0.03 wt%.
The present invention also provides a kind of preparation method of drinks, comprises following two steps:
A, raw-material preparation: Sha sour jujube is extracted and obtains extract by fruit in proportion; After Radix Astragali section, make with honey (honey); Be added in fluid nutrient medium with two selenium sugar, through submerged fermentation cultivate Se-rich lucid ganoderma hypha powder, dendrobium candidum is for subsequent use after crushed.
B, beverage preparation: first sealwort crude drug is cleaned, add after dendrobium candidum, (moxibustion) Radix Astragali, Se-rich lucid ganoderma hypha powder and soak one hour with 3 times of pure water, be heated to again 100 ℃ and extract filtration in 40 minutes, extract 1 hour with 100 ℃ of 2 times of pure water for the second time, extracted twice filtrate is incorporated in blend tank Sha sour jujube berry extract and epsilon-polylysine is added, strand is stumbled several minutes, then essence filter, filling, sterilizing.
Drinks provided by the invention, adopt on the one hand four tastes all to have and regulate immune Chinese medicine and Se-rich lucid ganoderma hypha powder compatibility, make to there is antifatigue, antitumor, antidotal effect, suitably select by the content to each Chinese medicine and organic selenium content, make the help mutually of each Chinese medicine, coordinated with each other, nutritious, ingredient stability; On the other hand, adopt biological antiseptic technology, do not add any chemical preservative and food additives, pure natural, mouthfeel are good.
The preparation method of drinks provided by the invention, by according to each Chinese medicine different components, adopts respectively diverse ways and step processing, extracts, effective ingredient is not destroyed, it is the highest that content reaches, and then mixes in proportion, allocates, and preparation technology is simple, easy to implement.
the specific embodiment:
The invention provides a kind of antifatigue, anti-ageing, antineoplastic drinks, described in contain sealwort 5~10wt%, (moxibustion) Radix Astragali 3~5 wt%, Sha sour jujube berry extract 3~8 wt%, Se-rich lucid ganoderma hypha powder 0.1~1 wt%, dendrobium candidum 1~5 wt% and epsilon-polylysine 0.01~0.03 wt%.
The present invention provides the preparation method of described drinks simultaneously.Drinks provided by the invention, one side adopts four tastes all to have and regulates immune Chinese medicine and the Se-rich lucid ganoderma hypha powder compatibility of cultivating by biological selenium-enriched technology, make to have antifatigue, antitumor, antidotal effect, has opened up the new way that human body is mended selenium; On the other hand, suitably select by the content to each Chinese medicine and organic selenium content, make the help mutually of each Chinese medicine; In addition, drinks provided by the invention does not add any chemical preservative and food additives, and pure natural, high nutrition, ingredient stability, mouthfeel are good.
Particularly, sealwort, the Radix Astragali, Sha sour jujube fruit and dendrobium candidum in the present invention are medicine and food, and Se-rich lucid ganoderma hypha powder is no more than under the prerequisite of the human normal demand upper limit at Se content, can be used as the material that health products use, and all has no side effect.
In drinks provided by the invention, wherein sealwort has merit nourshing Yin and drynsessmoistening prescription, that kidney-nourishing is mended essence, the Radix Astragali has the effect of nourishing qi and blood, Sha sour jujube has the energy of strengthening spleen and nourishing stomach, promoting blood circulation, and dendrobium candidum more has reinforcing stomach reg fluid, nourishing Yin and clearing heat power, and Se-rich lucid ganoderma hypha powder can not only make human body Selenium Supplement element, can also on control consumptive disease asthma, in control indigestion, inside protect liver kidney, control malignant tumor, improve immunity.
Aging is the general performance of body at degeneration function reduction in period and physiologic derangement.Old and feeble reason has many-side, and the reason of such as genetic aspect has that chromosome telomere is said, free oxygen theory etc.Chinese medicine delays senility, and the one, help is prolonged life, and the 2nd, eliminating evil eliminating disease and prolong life.And drinks of the present invention haves both at the same time.And in the present invention, help only tonifying Qi is enriched blood, but improve human immunity level, reach help object thereby adjust and transfer each internal organs function.Glossy ganoderma and sealwort are that Zhang Jingren teaches traditional anti-ageing side, in RPMI-1640, be respectively diluted to 50Ug/ml according to the use glossy ganodermas such as Jiang Yong, sealwort and three kinds of medicines of sealwort Ganoderma Mixture and carry out animal cell culture, in sealwort glossy ganoderma group passage to 58 generation, is still mellow and full glossy, have splitting ability, and in cellular control unit to 49 generation, almost do not have splitting ability.Astragalus polyose has bidirectional modulation blood sugar, reduces blood viscosity, improves lung and respiratory system immunocompetence; In Sha sour jujube fruit, be rich in multivitamin, there is radioresistance, antifatigue, strong body and be healthy and strong, promote longevity; Polysaccharide, alkaloid in dendrobium candidum all have the effect of building up health, nourishing skin.
Cancer is that the oncogene of body tissue cell is subject to the stimulation of adverse circumstances and activates, cause cell Disordered Splitting and self organization ability is out of control, it is a process by quantitative change to qualitative change, be closely related with human body autoimmune level, human immune system's three lines of defence is firm, and self-organizing control ability is strong, and cancer just can not occur, even if having minority cancer cell to disturb, also can it be swallowed up by macrophage.Phenolic compound in luxuriant and rich with fragrance compounds, quinones and Sha sour jujube fruit in triterpene compound, ergosterol compounds and dendrobium candidum in glossy ganoderma etc. can suppress and kill cancer cell effectively, astragalus polyose has effect of inducing apoptosis of tumour cell, and makes this beverage have anticancer function.
Fatigue, is a kind of subjective uncomfortable sensation, is divided into physiological fatigue and mental fatigue.From physiological mutation analysis, be the accumulation due to lactic acid and other metabolites,
muscle tonedecline, motion durability reduces; Due to the accumulation of carbon dioxide, stimulate respiratory center, also can cause yawning.Every disease progression all can occur tired to certain phase.Fatigue is that the asthenic symptoms of first gas consumption wound change with psychology, belongs to inferior health category, relates to the vital organs of the human body, mainly take spleen, liver, kidney as main.Chinese traditional treatment fatigue take strong kidney controlling nocturnal emission with astringent drugs, replenish qi to invigorate the spleen, Yangyin Rougan liver, nourish heart and allay excitement as main, and this drink formula all haves both at the same time.
Epsilon-polylysine described in the present invention, it is a kind of homotype monomer-polymer that contains 25~30 1B residues by streptomyces albus fermenting and producing, forming ε-amido link by the epsilon-amino of essential amino acid 1B and the α-carboxyl of another 1B is formed by connecting, have that security performance is high, dissolubility in water strong, the antibacterial biological preservative of broad-spectrum sterilization of Heat stability is good, can be absorbed completely as nutrition by human body, without any side effects to human body, there is long feature of the time of guaranteeing the quality.
The present invention also provides the preparation method of drinks, comprises the steps:
A, raw-material preparation: Sha sour jujube fruit extract in proportion obtain after extract, Radix Astragali section with honey moxibustion system, with two selenium sugar be added in fluid nutrient medium through submerged fermentation cultivate Se-rich lucid ganoderma hypha powder, the pulverizing of dendrobium candidum process is for subsequent use.
B, beverage preparation: first sealwort crude drug is cleaned, add after dendrobium candidum, (honey) Radix Astragali, Se-rich lucid ganoderma hypha powder and soak one hour with 3 times of pure water, be heated to again 100 ℃ and extract filtration in 40 minutes, extract 1 hour with 100 ℃ of 2 times of pure water for the second time, extracted twice filtrate is incorporated in blend tank Sha sour jujube berry extract and epsilon-polylysine is added, strand is stumbled several minutes, then ultrafiltration, filling, sterilizing.
Because sealwort selected in the present invention contains abundant polysaccharide and compound sugar, in Sha sour jujube berry extract, containing organic acid, make the sweet middle band acid of beverage, good taste, mouthfeel is good.
The present invention, in preparation method, for preventing organic acid and other Chinese medicine generation chemical reaction in Sha sour jujube fruit, prevents the destroyed decomposition of multivitamin simultaneously, makes extract and adopt to extract separately; The Radix Astragali adopts after sweet moxibustion, and effect of its tonifying middle-Jiao and Qi is more remarkable; The dissolution rate such as polysaccharide and dendrobine is the highest after crushed for dendrobium candidum; Selenium accumulation of Ganoderma Lucidum submerged fermentation is cultivated and is adopted two selenium sugar to make selenium source, can reduce following of other heavy metal element, than cultivating rich selenium effect and better quality with sodium selenate, sodium selenite and selenium mineral powder as selenium source.
Under preferable case, in steps A, the mass ratio of Sha sour jujube fruit crude drug and extract is 10:1; The mass ratio of moxibustion Radix Astragali crude drug and honey is 5:1.
In order to make technical problem solved by the invention, technical scheme and beneficial effect clearer, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
Embodiment 1:
Clean sealwort 100g, dendrobium candidum 50g are pulverized, add sweet Radix Astragali 50g, Se-rich lucid ganoderma hypha powder (selenium content 600ug/kg) 10g, soak 1 hour with 600ml pure water, be heated to 100 ℃ and extract and filter for 40 minutes, then extract filtration after 1 hour with 100 ℃ of 400ml pure water, extracted twice filtrate merges, add 80g Sha sour jujube berry extract, 200mg epsilon-polylysine, after fully strand is mixed, ultrafiltration, canned, sterilizing, obtain 1000ml drinks, S1.
Embodiment 2:
Se-rich lucid ganoderma hypha powder 0.5%, (honey) Radix Astragali 5%, sealwort 10%, the dendrobium candidum 2% that adopts S1 material preparation method to obtain adds for the first time 3 times of pure water and extracts 40 minutes, adding for the second time 2 times of pure water extracts 1 hour, twice pinch of liquid merges after filtration, in blend tank, add again Sha sour jujube berry extract of 3% and 0.02% epsilon-polylysine, mix after dissolving through strand, ultrafiltration again, filling, sterilizing, obtain feature capability beverage S2.
S1 and S2 test through animal model, all have following functions:
1, anti-tumor function: check the inhibitory action of this beverage on animal used as test mice with tumor S180 and the impact on superoxide dismutase through zoopery, result shows, S1 and S2 all have the effect that suppresses mice with tumor S180, high dose group reaches 79.3%, average inhibitory rate to 68.37%, with negative control group comparison, difference is extremely remarkable; Have the effect that improves SOD activity in body, with negative control group comparison, difference reaches (P ∠ 0.01) simultaneously.
2, anti-fatigue effect: mouse is divided into 4 groups at random, negative control group and basic, normal, high three dosage groups.Its mouse oral gavage various dose S1 and S2 sample 30 days, observe the variation of the rear blood lactic acid of each group of mice burden swimming time, liver glycogen and swimming, urea nitrogen, creatine kinase, leucocyte and hemoglobin index, compared with negative control group, three equal significant prolongations of dosage group mice burden swimming time, blood lactic acid and creatine kinase content all significantly reduce, difference has statistical significance, proves to improve exercise tolerance and accelerates to eliminate tired.
3, anti-senescence function: through old rats being carried out to more than 4 weeks feeding experiment with S1 and S2, employing sterilized water compares, measuring 12 old and feeble physiological and biochemical indexs sees, all have significantly or utmost point significant difference with contrasting, the wherein active high 125~175u/ml of SOD, low 22.7~the 32.2(LPO/nmol of heart LPO), part old rats grows black fur.
Above embodiment is only illustrated this drinks, does not limit the present embodiment.It should be pointed out that and do not breaking through the improvement of the processing method of having done under the prerequisite of this beverage function and the change of stem of noble dendrobium kind, also should belong to the protection domain of this patent.
Claims (8)
1. a drinks, it is characterized in that, described sealwort 5~10wt%, (moxibustion) Radix Astragali 3~5 wt%, Sha sour jujube berry extract 3~8 wt%, Se-rich lucid ganoderma hypha powder 0.1~1 wt%, dendrobium candidum 1~5 wt% and polylysine 0.01~0.03 wt% of containing is prepared from after extraction, filtration, allotment, ultrafiltration, filling, sterilization process.
2. drinks according to claim 1, it is characterized in that, described epsilon-polylysine is a kind of homotype monomer-polymer that contains 25~30 1B residues by streptomyces albus fermenting and producing, has that security performance is high, dissolubility in water strong, the antibacterial biological preservative of broad-spectrum sterilization of Heat stability is good.
3. drinks according to claim 1, is characterized in that, the preparation method of described function energy beverage, comprises following two steps:
A, raw material preparation: the sweet moxibustion of the Radix Astragali, the processing of Se-rich lucid ganoderma hypha powder, the extraction of Sha sour jujube fruit, dendrobium candidum are pulverized;
B, beverage processing allotment: comprise extraction, filtration, allotment, ultrafiltration, filling, the sterilizing of Chinese medicine.
4. drinks preparation method according to claim 3, described (moxibustion) Radix Astragali, is that honey and astragalus mongholicus tablet are formed in the ratio moxibustion system of 1:5.
5. drinks preparation method according to claim 3, it is characterized in that described Se-rich lucid ganoderma hypha powder is the lucidum strain high through screening polyoses content, selenium rich ability is strong, cultivate by the rich selenium deep layer of liquid, its selenium source is artificial two synthetic selenium sugar.
6. the preparation method of drinks according to claim 3, is characterized in that, described Sha sour jujube berry extract, and the mass ratio of Sha sour jujube fruit crude drug and extract is 10:1, pure water extracts, concentrated, spraying is dry obtains.
7. the preparation method of drinks according to claim 3, beverage processing preparation in step B, it is characterized in that, first sealwort crude drug is cleaned, add after the dendrobium candidum, (honey) Radix Astragali, Se-rich lucid ganoderma hypha powder through pulverizing with 3 times of pure water immersions one hour, be heated to again 100 ℃ and extract filtration in 40 minutes, extract 1 hour with 100 ℃ of 2 times of pure water for the second time, extracted twice filtrate is incorporated in blend tank Sha sour jujube berry extract and epsilon-polylysine is added, strand is stumbled several minutes, then essence filter, filling, sterilizing.
8. drinks according to claim 1, is characterized in that, described drinks is prepared by claim 3~7.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104287031A (en) * | 2014-07-29 | 2015-01-21 | 汤兴华 | Dendrobium officinale oral liquid capable of tranquilizing and tonifying qi |
CN105662942A (en) * | 2016-01-13 | 2016-06-15 | 时代生物科技(深圳)有限公司 | Composition for keeping skin's moisture and resisting oxidation as well as preparation method thereof |
CN105876029A (en) * | 2016-06-11 | 2016-08-24 | 邵则信 | Dendrobium candidum compound beverage and preparing method thereof |
CN106261281A (en) * | 2016-08-19 | 2017-01-04 | 铜仁市金农绿色农业科技有限公司 | A kind of Herba Dendrobii hippophae rhamnoides beverage and preparation method thereof |
CN106306885A (en) * | 2016-08-19 | 2017-01-11 | 铜仁市金农绿色农业科技有限公司 | Method for preparing dendrobium officinale drink |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1436560A (en) * | 2002-02-07 | 2003-08-20 | 阮沸翔 | Kidney and spleen invigorating Chinese medicine beverage for delaying senility |
CN1524453A (en) * | 2003-09-16 | 2004-09-01 | 任志田 | Sea-buckthorn astragalus root beverage |
KR100999436B1 (en) * | 2010-05-18 | 2010-12-09 | 주식회사 태경식품 | A method for preparation of garlic beverage having good flavor and taste |
-
2014
- 2014-03-06 CN CN201410079243.9A patent/CN103829340B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1436560A (en) * | 2002-02-07 | 2003-08-20 | 阮沸翔 | Kidney and spleen invigorating Chinese medicine beverage for delaying senility |
CN1524453A (en) * | 2003-09-16 | 2004-09-01 | 任志田 | Sea-buckthorn astragalus root beverage |
KR100999436B1 (en) * | 2010-05-18 | 2010-12-09 | 주식회사 태경식품 | A method for preparation of garlic beverage having good flavor and taste |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104287031A (en) * | 2014-07-29 | 2015-01-21 | 汤兴华 | Dendrobium officinale oral liquid capable of tranquilizing and tonifying qi |
CN105662942A (en) * | 2016-01-13 | 2016-06-15 | 时代生物科技(深圳)有限公司 | Composition for keeping skin's moisture and resisting oxidation as well as preparation method thereof |
CN105876029A (en) * | 2016-06-11 | 2016-08-24 | 邵则信 | Dendrobium candidum compound beverage and preparing method thereof |
CN106261281A (en) * | 2016-08-19 | 2017-01-04 | 铜仁市金农绿色农业科技有限公司 | A kind of Herba Dendrobii hippophae rhamnoides beverage and preparation method thereof |
CN106306885A (en) * | 2016-08-19 | 2017-01-11 | 铜仁市金农绿色农业科技有限公司 | Method for preparing dendrobium officinale drink |
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