CN103814012B - 吡啶衍生物及其作为鲜味促味剂的用途 - Google Patents

吡啶衍生物及其作为鲜味促味剂的用途 Download PDF

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Publication number
CN103814012B
CN103814012B CN201280046005.7A CN201280046005A CN103814012B CN 103814012 B CN103814012 B CN 103814012B CN 201280046005 A CN201280046005 A CN 201280046005A CN 103814012 B CN103814012 B CN 103814012B
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China
Prior art keywords
ylmethyl
base
compound
pyridine
ethanamide
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Chinese (zh)
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CN103814012A (zh
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J·A·埃林格斯
C·温凯
S·M·弗尔
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Givaudan SA
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Givaudan SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/205—Heterocyclic compounds
    • A23L27/2054—Heterocyclic compounds having nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88—Taste or flavour enhancing agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pyridine Compounds (AREA)
  • Seasonings (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201280046005.7A 2011-09-21 2012-09-20 吡啶衍生物及其作为鲜味促味剂的用途 Active CN103814012B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161537331P 2011-09-21 2011-09-21
US61/537,331 2011-09-21
PCT/EP2012/068495 WO2013041599A1 (en) 2011-09-21 2012-09-20 Pyridine derivates and their use as umami tastants

Publications (2)

Publication Number Publication Date
CN103814012A CN103814012A (zh) 2014-05-21
CN103814012B true CN103814012B (zh) 2016-03-23

Family

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CN201280046005.7A Active CN103814012B (zh) 2011-09-21 2012-09-20 吡啶衍生物及其作为鲜味促味剂的用途

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Country Link
US (1) US9573898B2 (enExample)
EP (1) EP2758374B1 (enExample)
JP (1) JP6180034B2 (enExample)
CN (1) CN103814012B (enExample)
IN (1) IN2014CN02036A (enExample)
WO (1) WO2013041599A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3019034B1 (en) 2013-07-01 2018-10-31 Givaudan SA Organic compounds
JP5805902B1 (ja) * 2015-04-15 2015-11-10 長谷川香料株式会社 香味変調剤
WO2016167153A1 (ja) 2015-04-15 2016-10-20 長谷川香料株式会社 ピリジン誘導体またはその塩を有効成分とする香味変調剤
JP6436890B2 (ja) * 2015-10-20 2018-12-12 長谷川香料株式会社 ピリジン誘導体を有効成分とする香味変調剤
JP6352227B2 (ja) * 2015-09-15 2018-07-04 長谷川香料株式会社 ２−（３−ベンジルオキシプロピル）ピリジンを含有する乳化組成物および粉末組成物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1349485A (zh) * 1999-04-30 2002-05-15 辉瑞产品公司 糖皮质激素受体调制剂
CN1918163A (zh) * 2003-12-23 2007-02-21 赛福伦公司 稠合吡咯并咔唑类化合物及其制备方法
US20100136136A1 (en) * 2006-09-28 2010-06-03 Exelixis, Inc. JAK-2 Modulators and Methods of Use
WO2011095533A1 (en) * 2010-02-04 2011-08-11 Givaudan Sa Oxalamide derivative as umami flavouring agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241779B2 (en) 2003-12-23 2007-07-10 Cephalon, Inc. Fused pyrrolocarbazoles
CN102471270B (zh) 2009-07-10 2014-07-02 奇华顿股份有限公司 具有鲜味香味的吡啶衍生物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1349485A (zh) * 1999-04-30 2002-05-15 辉瑞产品公司 糖皮质激素受体调制剂
CN1918163A (zh) * 2003-12-23 2007-02-21 赛福伦公司 稠合吡咯并咔唑类化合物及其制备方法
US20100136136A1 (en) * 2006-09-28 2010-06-03 Exelixis, Inc. JAK-2 Modulators and Methods of Use
WO2011095533A1 (en) * 2010-02-04 2011-08-11 Givaudan Sa Oxalamide derivative as umami flavouring agent

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CAS号：1190524-60-7;REGISTRY;《STN ON The WEB》;20091029;第3页 *
CAS号：332399-37-8;REGISTRY;《STN ON The WEB》;20010425;第4页 *
CAS号：431927-97-8;REGISTRY;《STN ON The WEB》;20020618;第4页 *
CAS号：432533-21-6;REGISTRY;《STN ON The WEB》;20020620;第3页 *
CAS号：830343-69-6;REGISTRY;《STN ON The WEB》;20050214;第3页 *
Studies on the synthesis of antiulcer agents. V. Synthesis and antiulcer activity of dihydrobenzofuranone derivatives;Kitazawa, M. ET AL;《Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan》;19891231;第109卷(第4期);第241-249页，第244-245页表II *
Studies on the synthesis of antiulcer agents.VI. Synthesis and antiulcer activity of dihydrobenzofuranone derivatives;Kitazawa, M. ET AL;《Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan》;19891231;第109卷(第10期);第718-736页，第728页表IV *

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Publication number Publication date
WO2013041599A1 (en) 2013-03-28
US9573898B2 (en) 2017-02-21
IN2014CN02036A (enExample) 2015-05-29
US20140342073A1 (en) 2014-11-20
CN103814012A (zh) 2014-05-21
EP2758374B1 (en) 2016-08-31
JP6180034B2 (ja) 2017-08-16
JP2014531448A (ja) 2014-11-27
EP2758374A1 (en) 2014-07-30

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