CN103800575A - Traditional Chinese medicine preparation for lowering blood pressure - Google Patents

Abstract

The invention aims to provide a traditional Chinese medicine preparation for lowering blood pressure. The traditional Chinese medicine preparation comprises following raw materials: 45 parts of feather cockscomb seeds, 45 parts of cassia seeds, 36 parts of sophora flower buds, 45 parts of crataegus pinnatifida bunge, 25 parts of wild chrysanthemums, 25 parts of lotus plumules, 30 parts of alisma plantago-aquatica, 30 parts of scutellaria baicalensis, 36 parts of uncaria rhynchophylla and 30 parts of gynostemma pentaphylla. According to the traditional Chinese medicine preparation provided by the invention, the materials are easily available and easy to manufacture; the combined utilization and the synergistic effect of traditional Chinese medicine components are realized; the traditional Chinese medicine preparation has the advantages of convenient utilization, low cost and clear use effects, is economical and practical and has no toxin or harms; the traditional Chinese medicine preparation is mainly used for patients with hypertension. The prepared tea beverage is convenient to drink and an extra decocting step is not needed.

Description

A kind of Chinese medicine preparation of blood pressure lowering

Technical field

The invention belongs to Chinese medicine preparation technical field, be specifically related to a kind of Chinese medicine preparation of blood pressure lowering.

Technical background

Hypertension is a kind of take arteriotony rising as feature, can be functional with heart, blood vessel, brain and kidney and other organs or the systemic disease of organic change, be divided into essential hypertension and secondary hypertension.Press the standard of WHO, as systolic pressure >=140mmHg and (or) diastolic pressure >=90mmHg, can be diagnosed as hypertension.Hypertension is early stage, and without obvious pathological change, long-term hypertension can cause whole body small artery pathological changes, and ductus arteriosus wall thickens and luminal stenosis, causes the important target organ heart, brain, nephridial tissue ischemia.Long-term hypertension and the risk factor of following can promote atherosclerotic formation and development, during this pathological changes is mainly involved, large artery trunks.Patient dies from cerebral hemorrhage, myocardial infarction, serious arrhythmia, renal failure more.

Patient has suffered from hypertension and has almost needed to take throughout one's life antihypertensive drugs.Because various depressor has side effect in various degree, patient is because worrying that Long-term taking medicine can cause damage to health, and is reluctant partner treatment; Or because of economic cause, can not adhere to taking medicine, make much Hypertension control bad, finally cause severe complication, even dead.Therefore hypertensive patient must adhere to seriality treatment, makes controlling of blood pressure within normal range.

Treatment hypertension is mainly to take the Western medicine with hypotensive effect at present, but Financial cost is higher, and larger to hepatic and renal function injure.Therefore the medicament that, antihypertensive effect is definite, side effect is little and cheap becomes many patients' demand.

Summary of the invention

The object of this invention is to provide a kind of have remarkable antihypertensive effect, the little and cheap Chinese medicine preparation of side effect, to make up the deficiencies in the prior art.

One is treated hypertensive Chinese medicine preparation, and the raw material packet of Chinese medicine preparation is containing 45 parts of Semen Celosiae, 45 parts of Semen Cassiaes, 36 parts of the Flos Sophorae Immaturus, 45 parts of Fructus Crataegis, 25 parts of Flos Chrysanthemi Indicis, 25 parts of Plumula Nelumbiniss, 30 parts of Rhizoma Alismatis, 30 parts of Radix Scutellariaes, 36 parts of Ramulus Uncariae Cum Uncis, 30 parts of Herb Gynostemmae Pentaphylli.

In order to improve effect, in above-mentioned preparation, be also added with Pheretima as guiding drug; The addition of Pheretima is 2 parts;

Above-mentioned Chinese medicine preparation is applied as tea beverage; While drinking, get 12～15 parts and put into pottery or glass material and the cup with filter mantle, add the hot boiled water of 200ml and brew after approximately 20 minutes, directly drink its medicine juice, and can repeatedly add brewed in hot water and drink, until medicine juice color is light tasteless.

Chinese medicine preparation of the present invention is used for the treatment of hypertension.

Chinese medicine preparation of the present invention is drawn materials conveniently, is easily made, and the Chinese prescription of employing is combined use, and synergism has easy to usely, with low cost, economical and practical, nontoxic, and the result of use advantage such as clearly, is mainly used in hypertensive patient.The tea product of making is drunk conveniently, does not need extra fried step.

The specific embodiment

Doctor trained in Western medicine thinks that mostly hypertension is because of blood fat and hypercholesterolemia, causes angiostenosis and vasospasm to cause, the suitable calmness for the treatment of, relaxing smooth muscle, blood fat reducing, diuresis etc.Inventor, by long-term research, has determined various component used in the present invention and proportioning.Wherein Semen Celosiae, the Flos Sophorae Immaturus, Flos Chrysanthemi Indici, Ramulus Uncariae Cum Uncis have effect of suppressing the hyperactive liver, pathogenic fire purging, endogenous wind stopping; Radix Scutellariae has calmness, relieves inflammation or internal heat, diuresis effect; Rhizoma Alismatis has the wet effect of diuretic; Plumula Nelumbinis energy tranquilizing by nourishing the heart, heat-clearing and toxic substances removing; Semen Cassiae has liver heat removing item, sharp kidney fat-reducing effect, Fructus Crataegi energy vessel softening, blood fat reducing, calmness, hepatoprotective; And Herb Gynostemmae Pentaphylli energy blood vessel dilating, prevent arteriosclerosis and thrombosis, can blood pressure lowering, blood fat, blood glucose; Pheretima has dredge the meridian passage, the effect of blood circulation promoting and blood stasis dispelling, thereby add Pheretima as extra conductant ingredient, more improve blood pressure lowering dredging collateral effect.Above-mentioned all medicines are assisted a ruler in governing a country mutually, play altogether effect of suppressing the hyperactive liver to relieve the wind syndrome, nourishing YIN for suppressing the hyperactive YANG, disperse blood stasis and dredge collateral.

Below in conjunction with example, Chinese medicine tea-drinking preparation of the present invention and effect thereof are described in detail.

Embodiment 1:

Get Semen Celosiae 45g, Semen Cassiae 45g, Flos Sophorae Immaturus 36g, Fructus Crataegi 45g, Flos Chrysanthemi Indici 25g, Plumula Nelumbinis 25g, Rhizoma Alismatis 30g, Radix Scutellariae 30g, Ramulus Uncariae Cum Uncis 36g, Herb Gynostemmae Pentaphylli 30g, Pheretima 2g mixes.Get 12～15g and add boiled water and brew after 20 minutes, just can drink.Mixture can add boiled water repeatedly, brews and drinks, until color is shallow tasteless.In the time that systolic pressure is greater than 180mmHg or diastolic pressure and is greater than 110mmHg, can every day 2 equivalent medicaments for tea-drinking, method for pouring is the same.

Embodiment 2:

Get Semen Celosiae 45g, Semen Cassiae 45g, Flos Sophorae Immaturus 36g, Fructus Crataegi 45g, Flos Chrysanthemi Indici 25g, embryo nelumbinis 25g, Rhizoma Alismatis 30g, Radix Scutellariae 30g, Ramulus Uncariae Cum Uncis 36g, Herb Gynostemmae Pentaphylli 30g, Pheretima 2g mixes; Mixture is got to 30 grams and enter marmite, the 300ml that adds water, little fire is decocted 10 minutes, then soaks after 20 minutes and make tea-drinking product; Every bu is converted warm water 5 times and is drunk.

First utilize zoopery to carry out the effect of verifying articles: to adopt the raw large squirrel (more easily bringing out successfully than purebred rat) of rat and home mouse hybridization, 4 monthly ages, putting into soundproof room raises in cages, noise stimulation can be sent by electric bell or speaker, tone generator is an audio oscillator, connects a 20W high pitch loudspeaker.Noise stimulation converts in 700～1000 cycle per seconds, and noise stimulation once also can stimulate 30 seconds every 1 minute for every 30 seconds.Such stimulation causes large squirrel hypertension, and average systolic is 130～140mmHg, has the 40% animal systolic pressure can be up to 160mmHg.Then the goods of being prepared by the present embodiment, with after brewed in hot water, offer experimental mouse as drinking water and quote, and drink after 24h, record average systolic and can be down to 115～130mmHg, and after the lasting week, experimental mouse has 95% hypertension symptom elimination; There is obvious antihypertensive effect than matched group.

In order to improve the effect of preparation, in mixture, be also added with Pheretima as guiding drug; The addition of Pheretima is 2 parts.Show by zoopery, than the matched group that does not add Pheretima, will shorten 2-3 days the course for the treatment of of the vascular hypertension treatment of the Chinese medicine preparation of the embodiment 2 of interpolation Pheretima to experimental mouse, and have meaning statistically.

Further illustrate its beneficial effect below in conjunction with clinical data and model case.

One, clinical observation

1. clinical data

This group case is totally 43 examples.Wherein, male's 24 examples, women's 19 examples, 52 years old mean age.Diagnosis all meets 2010 editions Chinese hypertension prevention and control guide Evaluation of Diagnostic Criteria of Hypertension.Wherein 1 grade of hypertension 13 example, 2 grades of hypertension 21 examples, 3 grades of hypertension 9 examples; Hypertension history 2～5 years, does not pass through the treatment of system or drug withdrawal more than 1 month voluntarily.

2. Therapeutic Method: all patients all require less salt, low fat diet, in the situation that not taking other drug, takes blood pressure lowering tea-drinking preparation, every day respectively at 9 in the morning and afternoons 4 point measurement blood pressure record, get twice meansigma methods as pressure value every day.

3. the effective standard of hypertension therapeutic: according to 2010 editions Chinese hypertension prevention and control guides, general hyperpietic's blood pressure lowering desired value is below 140/90mmHg, be associated with coronary heart disease, cardiac hypertrophy and cerebral blood supply insufficiency person, controlling of blood pressure is below 130/85mmHg, and patient is without dizzy uncomfortable.

4. safety is observed: before patient treatment and after treatment, within 1,3,6 month, carry out respectively routine blood test, routine urinalysis, and the inspections such as liver function, no abnormality seen changes.

5. therapeutic effect: after patient takes blood pressure lowering tea-drinking, 24 hours blood pressures have obvious decline.The 7 days blood pressures of taking medicine, 20～40/10～20mmHg that on average declines; Take medicine 14 days, 96.6% 2 grades and 3 grades of its blood pressures of hypertensive patient can maintain 130～140/90～95mmHg, and 1 grade of hypertension can be controlled at 120～130/80～90mmHg.Take medicine 4 weeks, patient all can maintain above-mentioned blood pressure level.

Two, model case

Case 1 Song, man, 49 years old, while being in hospital because of hemorrhoid, Measure blood pressure was 170/110mmHg, without uncomfortable.Give blood pressure lowering tea-drinking preparation 15g heating water for tea-drinking, Instant Drinks repeatedly, cut out blood pressure lowering tea-drinking at 9 in evening.After taking blood pressure lowering tea-drinking the same day, 4 hours blood pressures started to decline, and 8 hours blood pressure drops, to 140/95mmHg, without uncomfortable, are taken medicine 3, and blood pressure is down to 130/85mmHg.

Case 2 Zhao, female, 53 years old, hypertension 6 years, because of economic cause, withdraw depressor more than 50 days, go to a doctor because headache is dizzy, blood pressure is 190/115mmHg, gave blood pressure lowering tea-drinking preparation the same day and drink, next day, blood pressure was reduced to 150/95mmHg, the dizzy transference cure of patient's headache, within 7 days, blood pressure is down to 140/90mmHg, and patient feels good.

Case 3 Wang, man, 67 years old, because having the sense of beating, dizziness and distending sensation of the head goes to a doctor, and blood pressure is 190/110mmHg, give Chinese hypotensor tea-drinking preparation 15g hot water Instant Drinks, every day 2 times, after taking medicine 4 hours, blood pressure drops is to 170/105mmHg, and within 8 hours, blood pressure is down to 160/100mmHg, within 12 hours, blood pressure is down to 130/95mmHg, maintains this blood pressure patient suitable symptom invariably.Keep equal medication dose, every day, measuring blood pressure remained on 135～140/85～95mmHg, and patient is without discomfort.

Claims (6)

1. a Chinese medicine composition, is characterized in that described Chinese medicine composition comprises 45 parts of Semen Celosiae, 45 parts of Semen Cassiaes, 36 parts of the Flos Sophorae Immaturus, 45 parts of Fructus Crataegis, 25 parts of Flos Chrysanthemi Indicis, 25 parts of Plumula Nelumbiniss, 30 parts of Rhizoma Alismatis, 30 parts of Radix Scutellariaes, 36 parts of Ramulus Uncariae Cum Uncis, 30 parts of Herb Gynostemmae Pentaphylli.

2. Chinese medicine composition as claimed in claim 1, is characterized in that, in described Chinese medicine composition, is added with Pheretima.

3. Chinese medicine composition as claimed in claim 2, is characterized in that, described Pheretima addition is 2 parts.

4. the using method of Chinese medicine composition claimed in claim 1, is characterized in that, gets 12～15 parts and puts into pottery or glass material and the cup with filter mantle, after heating boiled water brews approximately 20 minutes, drinks.

5. the application of Chinese medicine composition claimed in claim 1 in the hypertensive goods of preparation treatment.

6. the hypertensive goods for the treatment of, is characterized in that the aqueous extract that described goods are Chinese medicine composition claimed in claim 1.