CN103784247A - Cold therapy gel - Google Patents
Cold therapy gel Download PDFInfo
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- CN103784247A CN103784247A CN201410076623.7A CN201410076623A CN103784247A CN 103784247 A CN103784247 A CN 103784247A CN 201410076623 A CN201410076623 A CN 201410076623A CN 103784247 A CN103784247 A CN 103784247A
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Abstract
The invention relates to cold therapy gel. The cold therapy gel comprises, by mass (in units of 500g) 5g-15g of Carbomer940GE, 25g-35g of ethanol, 5g-15g of peppermint and the balance de-ionized water. Volatile liquid gel is adopted as the cold therapy gel and contains the peppermint, the water and macromolecular substances. The roll-on mode is adopted, and effective components of the finished gel are directly spread on the forehead, the temples, the neck, the armpits, the inner sides of the thighs, soft tissue contusion parts, an arthralgia part and other parts. Cold therapy and physical cooling are performed on a fever patient, an acute sprain patient, a soft tissue contusion patient, a heatstroke patient and other patients by utilizing the principle of the cold therapy. The cold therapy gel prevents heatstroke, refreshes people and has the advantages of being fast in defervescence, safe, reliable, free of side effects, convenient to use and capable of being used on multiple parts of the whole body, thereby being suitable for adult patients, children patients and other patients.
Description
Technical field
The present invention relates to a kind of cold treatment gel, belong to medical formula technique field.
Background technology
Human body fever is that one drops to normally higher than normal body temperature.The reason that causes human body fever has a lot, can be divided into by and large following three major types: (1) extrinsic factor: body temperature is affected by external environment, during as sky heat, clothes is worn too much, water is drunk very little, space air does not circulate.(2) intrinsic factor: sick, flu, tracheitis, throat inflammation or other diseases.(3) other factors: as protective inoculation, comprise the reactions such as measles, cholera, diphtheria, hundred mouthfuls are coughed, tetanus.
Having a high fever is one of the anti-infective mechanism of supporting in body.The system of defense that our health is transferred self by the body temperature that raises is killed external pathogenic bacteria (in general, pathogenic bacteria will be dead more than 39 ℃ time), thereby shortens the disease time, strengthens antibiotic effect.If (37-38.5 ℃) bring down a fever with medicine in the time having some inkling of a cold, can make the antibacterial in body temporarily become torpor, and they are developed immunity to drugs, once revivable, often more refractory is treated.Because fever is a kind of normal immunoreation, contribute to leukocyte opposing bacteriotoxin, there is certain resistance against diseases; The pattern of fever of observing fever can the assisted diagnosis cause of disease, brings down a fever simply and misleads on the contrary, so not too high body temperature needn't anxiously be brought down a fever.But fever can increase metabolism, causes the consumption of energy; Especially infant fever causes moisture evaporation, causes dehydration; And hyperpyrexia convulsion easily occurs infant, cause that injury is unnecessary therefore let alone fever.
The mode of in general bringing down a fever has following:
(1) physics is brought down a fever: Physical temperature-lowering is applicable to Gao Re and circulates good patient.Feature is that method is simple, and untoward reaction is few.Comprising: (1a) warm sponge bath: be applicable to high hot baby.Water temperature should be a little less than baby's skin temperature (32 ℃-34 ℃).Skin is accepted after cold stimulation, can make blood capillary shrink, and expansion again, reaches cooling-down effect then.When rubbing bath, also can stimulate the passive expansion of blood vessel with massage manipulation, promote dispersing of heat.Note firmly wanting evenly when rubbing bath, massage gently several under, can also promote vasodilation.Wipe to the rich blood vessel such as axillary fossa, groin place's time of staying a little longer, to help heat radiation.The each rubbing bath 3-5 minute in extremity and back.(1b) alcohol bath: will note the concentration of ethanol while using alcohol bath, generally be advisable with 30%-50% concentration.Ethanol is too not cool, and temperature is advisable with 32 ℃-35 ℃.Dip after ethanol wiping regularly with gauze or towel.Normally first from the cervical region of infant, from top to down is wiped to the back of the hand along upper arm outside.Then wipe to the palm of the hand along Medial upper arm through axillary fossa.After upper limb wipes, wipe examination back downwards from cervical region, when rubbing bath, pat back with another have gentle hands forlement, with blood circulation promoting.Finally start wiping lower limb from ilium portion, method is identical with wiping upper limb.About each position wiping 3 minutes., the time of staying should be a little longer when at the position such as wiping oxter, ancon, the centre of the palm, groin, the sufficient heart, to improve radiating effect.(1c) saline enema: it is remarkable that cool brine is filled with the cooling-down effect of soup, but be not suitable for operating in family.(1d) cold compress: if hyperpyrexia cannot tolerate, can adopt cold compress to help to reduce body temperature.On forehead, wrist, shank, respectively put a clammy towel, other positions should cover with medicated clothing.In the time that cold compress reaches body temperature, should change once, repeatedly until burn move back.Also ice cube can be wrapped in cloth bag, be placed on forehead.(1e) hot compress: if body temperature is not too high, can adopt hot compress to bring down a fever.With hot wet towel wiping patient forehead, extremity repeatedly, make heat dissipating body, until bring down a fever.But, if more than body temperature rise to 39 ℃, be sure not to re-use hot compress and bring down a fever, should be with cold compress processing, in order to avoid body temperature continues to raise.(1f) bath: bath and can play the symptom of alleviating heating.(1g) liquid make-up: in the time having a high fever, the health heat radiation of can sweating; But while having a high fever, health can be closed sweat gland because running off too many moisture, and to stop further water loss, this cannot dispel the heat health.Solution is exactly liquid make-up, drinks a large amount of boiled water and fruit and vegetable juice, and wherein fruit and vegetable juice is containing abundant vitamin and mineral, especially beet juice and Radix Dauci Sativae juice.If you want to drink Fructus Lycopersici esculenti juice, should select the product of low sodium.During fever, should avoid food, until situation takes a turn for the better.If vomiting situation is not serious, can also eats ice cube and bring down a fever.In ice making box, pour fruit juice into, ice becomes ice cube, also can in ice tray, put into Fructus Vitis viniferae or Fructus Fragariae Ananssae, and the child that this is especially had a high fever welcomes.
(2) medicine is brought down a fever: general febrifuge has water preparation, lozenge, suppository and injection, the using priciple that they are had nothing in common with each other.Specifically comprise: (2a) water preparation is gentleer, what the most generally use is the syrup containing acetaminophen, as children's Merrill Lynch syrup, children's's bufferin drop etc.(2b) aspirin lozenge is brought down a fever effective.But Lei Shi syndrome may be caused in aspirin, thus some specific period can not use.(2c) suppository is the medicine of filling in from anus, is mainly absorbed by rectum, and effect ratio faster.(2d) adopt injection injection.(2e) suitably take analgesic.Adult takes 2 tablets of aspirin or 2 acetaminophen, within every 4 hours, takes once.The advantage of acetaminophen is that less people is to its allergy.Due to the model of action of aspirin and acetaminophen, some is different, if therefore you feel to use and anyly all cannot effectively control and have a high fever, there is no harm in two kinds and use.Within every 6 hours, take 2 tablets of aspirin and 2 acetaminophen.
The above-mentioned mode of bringing down a fever, adopts febrifuge, if dosage control is bad, has hidden danger.And the general physics mode of bringing down a fever, because need various media, causes the inconvenience of use, therefore, also need to be improved the mode that adopts suitable physics to bring down a fever.
Summary of the invention
The object of the present invention is to provide a kind of cold treatment gel, bring down a fever to carry out physics for patient better, more convenient to use, and the effect of bringing down a fever is remarkable, is applicable to various crowds and uses.
To achieve these goals, technical scheme of the present invention is as follows.
A kind of cold treatment gel, be made up of Carbomer940GE, ethanol, Oleum menthae and deionized water, above-mentioned each component is respectively take quality (500 grams as unit): 5~15 grams of Carbomer940GE, 25~35 grams of ethanol, 5~15 grams of Oleum menthae, surplus is deionized water.
Further, above-mentioned each component is respectively take quality (500 grams as unit): 10 grams of Carbomer940GE, 30 grams of ethanol, 10 grams of Oleum menthae, 450 grams of deionized waters.
Further, the concrete preparation process of above-mentioned cold treatment gel is:
(1) Oleum menthae of above-mentioned mass fraction is joined in ethanol, obtain A component solution.
(2) under stirring, Carbomer940 is dispersed in deionized water, dissolve completely, at the A component solution that adds the prepared acquisition of step (1).
(3) in the solution of preparing in step (2), adding mass percent is that 18% sodium hydroxide neutralizes.
(4) adopt step (3) method to prepare the latex that is creamy white, its PH=7, viscosity is 32200 centipoises.
(5) make finished product after adding hydroxy benzoic acid to process in the prepared latex of step (4).
The mechanism of action of above-mentioned cold treatment gel is, utilizes transdermal drag delivery that the compositions such as pure natural Herba Menthae are seen through to skin surface and is deep into subcutaneous skin corium, pyretic toxicity in body given out external, arrives the object that physics is brought down a fever.Use position: be applied in the positions such as forehead, temple, cervical region, axillary fossa, femoribus internus, do not affect wearing clothes, multiple location is smeared simultaneously, and onset is faster, better effects if.Effective time: smear and once can keep more than 30 minutes, can also continue subsequently to smear, until somatosensory is comfortable.Using method, multiple location ballpoint is smeared, and every bottle can use up to a hundred times.Ease of use: liquid gel water white transparency, without using vestige, easy to carry, use at any time, smear in the time and can act on one's own.
This beneficial effect of the invention is: above-mentioned cold treatment gel adopts volatile liquid gel to contain Oleum menthae, water, polymer substance, and adopt ballpoint pattern, the effective ingredient of finished product is directly applied to forehead, temple, cervical region, axillary fossa, femoribus internus, soft tissue contusion, the positions such as arthralgia, utilize the principle of cold treatment to heating, acute sprain, soft tissue contusion, the patients such as heatstroke carry out cold compress physical therapy Physical temperature-lowering, sunstroke prevention is refreshed oneself, have and bring down a fever soon, safe and reliable, have no side effect, easy to use, the advantage that whole body multiple location uses, be applicable to adult, the patients such as child.
Above-mentioned Leng Liao gel application section office are as follows: (1) department of pediatrics: fever of children utilizes the principle of cold treatment, patient is carried out to Physical temperature-lowering, and have no side effect, evident in efficacy.(2) internal medicine: to fever patient, carry out Physical temperature-lowering.Heatstroke patient, smears forehead, temple, cervical region, has sunstroke prevention, refreshment effect.(3) orthopaedics: acute sprain, soft tissue contusion carried out cold compress physical therapy to injury in injured 24 hours, extenuated pain with red and swollen.(4) surgery: low grade fever patient after operation, can be used for physics and bring down a fever, evident in efficacy.
The specific embodiment
Below in conjunction with embodiment, the specific embodiment of the present invention is described, to better understand the present invention.
embodiment 1:
A kind of cold treatment gel, is made up of Carbomer940GE, ethanol, Oleum menthae and deionized water, and above-mentioned each component is respectively take quality (500 grams as unit): 5 grams of Carbomer940GE, and 25 grams of ethanol, 5 grams of Oleum menthae, surplus is deionized water.
The concrete preparation process of above-mentioned cold treatment gel is:
(1) Oleum menthae of above-mentioned mass fraction is joined in ethanol, obtain A component solution.
(2) under stirring, Carbomer940 is dispersed in deionized water, dissolve completely, at the A component solution that adds the prepared acquisition of step (1).
(3) in the solution of preparing in step (2), adding mass percent is that 18% sodium hydroxide neutralizes.
(4) adopt step (3) method to prepare the latex that is creamy white, its PH=7, viscosity is 32200 centipoises.
(5) make finished product after adding hydroxy benzoic acid to process in the prepared latex of step (4).
implement 2:
A kind of cold treatment gel, is made up of Carbomer940GE, ethanol, Oleum menthae and deionized water, and above-mentioned each component is respectively take quality (500 grams as unit): 15 grams of Carbomer940GE, and 35 grams of ethanol, 15 grams of Oleum menthae, surplus is deionized water.
The concrete preparation process of above-mentioned cold treatment gel is:
(1) Oleum menthae of above-mentioned mass fraction is joined in ethanol, obtain A component solution.
(2) under stirring, Carbomer940 is dispersed in deionized water, dissolve completely, at the A component solution that adds the prepared acquisition of step (1).
(3) in the solution of preparing in step (2), adding mass percent is that 18% sodium hydroxide neutralizes.
(4) adopt step (3) method to prepare the latex that is creamy white, its PH=7, viscosity is 32200 centipoises.
(5) make finished product after adding hydroxy benzoic acid to process in the prepared latex of step (4).
embodiment 3:
A kind of cold treatment gel, is made up of Carbomer940GE, ethanol, Oleum menthae and deionized water, and above-mentioned each component is respectively take quality (500 grams as unit): 10 grams of Carbomer940GE, 30 grams of ethanol, 10 grams of Oleum menthae, 450 grams of deionized waters.
The concrete preparation process of above-mentioned cold treatment gel is:
(1) Oleum menthae of above-mentioned mass fraction is joined in ethanol, obtain A component solution.
(2) under stirring, Carbomer940 is dispersed in deionized water, dissolve completely, at the A component solution that adds the prepared acquisition of step (1).
(3) in the solution of preparing in step (2), adding mass percent is that 18% sodium hydroxide neutralizes.
(4) adopt step (3) method to prepare the latex that is creamy white, its PH=7, viscosity is 32200 centipoises.
(5) make finished product after adding hydroxy benzoic acid to process in the prepared latex of step (4).
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.
Claims (3)
1. a cold treatment gel, it is characterized in that: be made up of Carbomer940GE, ethanol, Oleum menthae and deionized water, above-mentioned each component is respectively take quality (500 grams as unit): 5~15 grams of Carbomer940GE, 25~35 grams of ethanol, 5~15 grams of Oleum menthae, surplus is deionized water.
2. cold treatment gel according to claim 1, is characterized in that: each component of described cold treatment gel is respectively take quality (500 grams as unit): 10 grams of Carbomer940GE, 30 grams of ethanol, 10 grams of Oleum menthae, 450 grams of deionized waters.
3. cold treatment gel according to claim 1 and 2, is characterized in that: the concrete preparation process of described cold treatment gel is:
(1) Oleum menthae of above-mentioned mass fraction is joined in ethanol, obtain A component solution;
(2) under stirring, Carbomer940 is dispersed in deionized water, dissolve completely, at the A component solution that adds the prepared acquisition of step (1);
(3) in the solution of preparing in step (2), adding mass percent is that 18% sodium hydroxide neutralizes;
(4) adopt step (3) method to prepare the latex that is creamy white, its PH=7, viscosity is 32200 centipoises;
(5) make finished product after adding hydroxy benzoic acid to process in the prepared latex of step (4).
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CN201410076623.7A CN103784247A (en) | 2014-03-05 | 2014-03-05 | Cold therapy gel |
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Cited By (3)
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CN105412994A (en) * | 2015-12-16 | 2016-03-23 | 安徽苗德堂药业有限公司 | Bead material of collateral-activating cold therapy bead device and preparation method of bead material |
CN108159023A (en) * | 2017-12-22 | 2018-06-15 | 杭州高斯博医疗用品有限公司 | A kind of preparation method and product of cold compress hydrogel plaster |
CN108671021A (en) * | 2018-05-08 | 2018-10-19 | 长沙爱扬医药科技有限公司 | A kind of Chinese herbal medicine temperature-reducing paste containing mint ingredient |
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CN1879665A (en) * | 2006-05-15 | 2006-12-20 | 贵州柏强制药有限公司 | Quickly-acting defervescence plaster used for infants and preparation method thereof |
CN101336960A (en) * | 2007-11-02 | 2009-01-07 | 徐宝恒 | Defervescence paste |
CN101756761A (en) * | 2009-12-31 | 2010-06-30 | 武汉天地通生物工程有限公司 | Heating patch with coupling agent and preparation process thereof |
CN102038746A (en) * | 2009-10-22 | 2011-05-04 | 上海中邦斯瑞生物药业技术有限公司 | Antipyretic pharmaceutical composition |
CN102319142A (en) * | 2011-05-26 | 2012-01-18 | 谭波 | Antipyretic gel |
CN103191185A (en) * | 2013-04-20 | 2013-07-10 | 江苏迪沃生物制品有限公司 | Antipyretic gel |
CN103372186A (en) * | 2012-04-20 | 2013-10-30 | 湖北精耕医用材料有限公司 | Polymer plant gel |
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2014
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Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1325740A (en) * | 2001-06-18 | 2001-12-12 | 崔丹阳 | Quick-acting defervescent wet tissue |
CN1879665A (en) * | 2006-05-15 | 2006-12-20 | 贵州柏强制药有限公司 | Quickly-acting defervescence plaster used for infants and preparation method thereof |
CN101336960A (en) * | 2007-11-02 | 2009-01-07 | 徐宝恒 | Defervescence paste |
CN102038746A (en) * | 2009-10-22 | 2011-05-04 | 上海中邦斯瑞生物药业技术有限公司 | Antipyretic pharmaceutical composition |
CN101756761A (en) * | 2009-12-31 | 2010-06-30 | 武汉天地通生物工程有限公司 | Heating patch with coupling agent and preparation process thereof |
CN102319142A (en) * | 2011-05-26 | 2012-01-18 | 谭波 | Antipyretic gel |
CN103372186A (en) * | 2012-04-20 | 2013-10-30 | 湖北精耕医用材料有限公司 | Polymer plant gel |
CN103191185A (en) * | 2013-04-20 | 2013-07-10 | 江苏迪沃生物制品有限公司 | Antipyretic gel |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105412994A (en) * | 2015-12-16 | 2016-03-23 | 安徽苗德堂药业有限公司 | Bead material of collateral-activating cold therapy bead device and preparation method of bead material |
CN108159023A (en) * | 2017-12-22 | 2018-06-15 | 杭州高斯博医疗用品有限公司 | A kind of preparation method and product of cold compress hydrogel plaster |
CN108671021A (en) * | 2018-05-08 | 2018-10-19 | 长沙爱扬医药科技有限公司 | A kind of Chinese herbal medicine temperature-reducing paste containing mint ingredient |
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Application publication date: 20140514 |