CN103768538A - Medicine for treating knee osteoarthritis - Google Patents
Medicine for treating knee osteoarthritis Download PDFInfo
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- CN103768538A CN103768538A CN201410061359.XA CN201410061359A CN103768538A CN 103768538 A CN103768538 A CN 103768538A CN 201410061359 A CN201410061359 A CN 201410061359A CN 103768538 A CN103768538 A CN 103768538A
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Abstract
The invention discloses a medicine for treating knee osteoarthritis. The medicine is prepared from pinfa raspberry root and leaf, crateva unilocularis, hexaphyllous radix gentianae, cynanchum paniculatum, wengbo (Chinese character), jasmine, aspongopus, notopterygium root, radix curcumae longae and borneol. The medicine can be clinically applied to treatment of the knee osteoarthritis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of medicine for the treatment of knee osteoarthritis.
Background technology
Knee osteoarthritis is sclerotin, synovial membrane, the joint capsule and multi-faceted, the chronic inflammatory disease at many levels, in various degree of other structures of joint of involving take articular cartilage degeneration as core.Its clinical manifestation mostly is that the gonalgia, swelling, dysfunction, joint are thick, Varus deformity etc.Knee osteoarthritis mostly be old people, be the disease of deficiency in origin and excess in superficiality, the long-term lacking activity due to the gonalgia in addition, causes local QI-blood circulation deficiency, muscle is become homeless foster, the numbness of aching, of a specified duration myoatrophy and the osteoporosis of easily causing.
Summary of the invention
The object of the present invention is to provide the medicine of the treatment knee osteoarthritis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix seu Folium Rubi Pinfaensis, a tree dish, Radix Gentianae, Radix Cynanchi Paniculati, Weng Bo, Fructus Gardeniae, Aspongopus, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Borneolum Syntheticum according to certain compatibility requirement, through being processed into.
Preparing medicine of the present invention is made up of following raw material medicaments: Radix seu Folium Rubi Pinfaensis 40-60 part, tree dish 30-50 part, Radix Gentianae 30-50 part, Radix Cynanchi Paniculati 20-30 part, Weng Bo 20-30 part, Fructus Gardeniae 20-30 part, Aspongopus 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Rhizoma Curcumae Longae 10-20 part, Borneolum Syntheticum 8-12 part.
Optimum weight part of medicine material medicine of the present invention is: 50 parts of Radix seu Folium Rubi Pinfaensis, 40 parts of dishes of tree, 40 parts of Radix Gentianae, 25 parts of Radix Cynanchi Paniculatis, 25 parts of Weng Bo, 25 parts of Fructus Gardeniaes, 15 parts of Aspongopuss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts, Rhizoma Curcumae Longae, 10 parts of Borneolum Syntheticums.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix seu Folium Rubi Pinfaensis: salty, cool.Return liver, kidney channel.Cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment.It is clinical that for heat in blood haematemesis, hematuria, has blood in stool, metrorrhagia, and rheumatic arthritis, eczema, is with inferior disease.
A tree dish: bitter, cold.Heat-clearing and toxic substances removing, stomach invigorating.Clinical in acute filthy disease heating, rotten skin ulcer, venom, stomachache, the diseases such as rheumatic arthritis.
Radix Gentianae: bitter, warm.Removing toxic substances, dampness.Clinical in anthrax, rheumatic arthralgia.
Radix Cynanchi Paniculati: pungent, hot, return spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching, promoting blood circulation and detoxication, detumescence.Clinical in gastropathy, toothache, rheumatic arthralgia, lumbago, epigastric pain, cholecystitis, urine water conservancy, has loose bowels, dysentery, eczema, urticaria, venom.
Weng Bo: sweet, warm.Yang invigorating is dispersed, removing toxic substances rash, dispelling wind for relieving itching.Cure mainly measles without adequate eruption, high heat, cough, parotitis, rheumatic arthritis, rubella pruritus etc.
Fructus Gardeniae: bitter, cold, GUIXIN, liver, lung, stomach warp.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.For calentura unhappiness, sore swollen toxin.
Aspongopus: salty, warm.Return liver,kidney,spleen warp.Promoting the circulation of QI to relieve pain, warming the kidney to invigorate YANG.For incoordination between the liver and stomach, abdominal distention, lumbago, the diseases such as sexual impotence.
Rhizoma Et Radix Notopterygii: acrid, bitter, warm.Return bladder, kidney channel.Cold expelling dispels the wind, removing dampness to relieve pain.For anemofrigid cold, headache general pain, rheumatic arthralgia, shoulder pain etc.
Rhizoma Curcumae Longae: bitter in the mouth, pungent, warm in nature.Return spleen, Liver Channel.Removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.The all cards of stagnation of QI and blood, born of the same parents' abdomen hypochondriac pain, dysmenorrhes, the stagnant stomachache of the stasis of blood in puerperal, rheumatic arthralgia, traumatic injury, carbuncle etc.
Borneolum Syntheticum: pungent, bitter, cool.GUIXIN, lung meridian.The refreshment of having one's ideas straightened out, heat radiation pain relieving, improving eyesight removing nebula.For apoplexy, calentura coma, deafness with qi stagnation, sore throat, aphtha, carbuncle, hemorrhoid, the diseases such as enterobiasis.
Motherland's medical science is thought its morbidity and caused by liver and kidney deficiency, cold-damp invasion, and retardance meridians, due to phlegm-turbidity and blood stasis blood stasis is stagnant, are very important pathological factors at acute attack stage especially.Radix seu Folium Rubi Pinfaensis expelling wind and removing dampness, removing toxic substances in the present invention are monarch drug; A tree dish heat-clearing and toxic substances removing, Radix Gentianae removing toxic substances, dampness, be ministerial drug; Radix Cynanchi Paniculati promoting blood circulation and detoxication, Weng Bo dispels the wind, detoxifies, Fructus Gardeniae dampness removing, removing toxic substances, Aspongopus promoting the circulation of QI to relieve pain, notopterygium wind dispelling, removing dampness to relieve pain, Rhizoma Curcumae Longae circulation of qi promoting stops, Borneolum Syntheticum pain relieving.Find that through clinical practice knee osteoarthritis is had to unique curative effect, reach the object for the treatment of knee osteoarthritis.
Medicine of the present invention was in 2008 to 2011 the routine patients of clinical observation knee osteoarthritis 55, and clinical report is as follows:
1, physical data
In 55 routine patients, age 45-76 year, the course of disease is many at 3 months to 10 years, 62 years old mean age.
2, diagnostic criteria
Draft with reference to " arthritis diagnosis and treatment guide draft gonarthritis in 2002 diagnostic criteria of rheumatism branch of Chinese Medical Association ":
1. nearly one month frequent gonalgia repeatedly; 2. X-ray film (erect position or Weight carrying position) joint space narrows; 3. limpid, the thickness of joint fluid (at least 2 times), WBC≤200/ml; 4. person in middle and old age person (>=40 years old); 5. knee joint deadlock≤30 minute in morning; 6. when movable, there is friction sound.Meet and 1. 2. or 3. 5. 6. or 1. 4. 5. 6. form diagnosis.According to sign: the 1. gonalgia, walking function obstacle, when fatigue and stair activity, symptom increases the weight of, and involves periarticular myalgia.2. health check-up knee joint is unrestrained swollen, patella and inside and outside Xiyan place tenderness+, patella grinds pain, floating patella test+, it is limited that knee joint is stretched flex, atrophy of quadriceps femoris.
3, Therapeutic Method
3.1 prescriptions: Radix seu Folium Rubi Pinfaensis 50g, tree a dish 40g, Radix Gentianae 40g, Radix Cynanchi Paniculati 25g, Weng Bo 25g, Fructus Gardeniae 25g, Aspongopus 15g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Curcumae Longae 15g, Borneolum Syntheticum 10g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 10 days were 1 course for the treatment of at 1 dose of every day.
4, therapeutic outcome:
4.1 treatment evaluation criterias, " traditional Chinese medical science disease Standardization of diagnosis and curative effect " formulated according to State Administration of Traditional Chinese Medicine judged:
Clinical cure: knee joint swelling, pain disappear, bends and stretches range of activity and recovers normal, and walking freely;
Effective: knee joint swelling substantially disappears or obviously goes down, and pain obviously alleviates, bend and stretch range of activity normal;
Take a turn for the better: knee joint swelling and pain all have and alleviates in various degree and alleviate, and bend and stretch range of activity and are also improved;
Invalid: knee joint swelling and pain are all without alleviating.
4.2 results: in 55 routine patients, clinical cure 31 examples (56.4%), effective 11 examples (20%), 9 examples that take a turn for the better (16.4%), invalid 4 examples (7.2%), total effective rate is 92.8%.
Model case
1, Zhao, man, 59 years old, nearly 1 year of two gonalgia, over nearly 1 month, right swelling and pain in knee obviously increases the weight of, and upper all needs staircase downstairs, seat dysstasia is met overcast and rainy symptom obvious, morning deadlock, idol has interlocking phenomenon.Check: inner side tenderness under kneecap: left knee joint (+), right knee joint (++); Right knee joint is micro-swollen, right Range of motion of knee joint: 45 °; Tongue is greasy in vain, stringy and rolling pulse.Diagnosis: knee osteoarthritis.Take medicine of the present invention, treat 2 courses for the treatment of, two swelling and pain in knee obviously alleviate, and all the other symptoms are also alleviation trend, continue to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
2, Lee, female, 68 years old, existing 15 years of two knee joint sorenesses, had Knee Trauma history and the history of catching cold.Though through treatments such as Chinese medicine and western medicine pain relievings, stop when two knee joint sorenesses are done still time, recently, knee joint soreness increases the weight of, stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: knee joint is bone hypertrophy, and joint space narrows.Check: two knee joints are tenderness (+) around, mild swelling and limping, two knee joint mobilities are limited to 45 °, have interlocking to levy, McMurray's test (+), lateroflexion (±), floating kneecap (±).Diagnosis: knee osteoarthritis.Take medicine of the present invention, 1 dose of every day, after 3 courses for the treatment of, rear two knee joints are ached and are alleviated, and swelling disappears, and all the other symptoms alleviate.Continue to take 4 courses for the treatment of, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of medicine for the treatment of knee osteoarthritis, is to be made up of Radix seu Folium Rubi Pinfaensis 40g, tree a dish 30g, Radix Gentianae 30g, Radix Cynanchi Paniculati 20g, Weng Bo 20g, Fructus Gardeniae 20g, Aspongopus 10g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Curcumae Longae 10g, Borneolum Syntheticum 8g.
Embodiment 2, a kind of medicine for the treatment of knee osteoarthritis, is to be made up of Radix seu Folium Rubi Pinfaensis 50g, tree a dish 40g, Radix Gentianae 40g, Radix Cynanchi Paniculati 25g, Weng Bo 25g, Fructus Gardeniae 25g, Aspongopus 15g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Curcumae Longae 15g, Borneolum Syntheticum 10g.
Embodiment 3, a kind of medicine for the treatment of knee osteoarthritis, is to be made up of Radix seu Folium Rubi Pinfaensis 60g, tree a dish 50g, Radix Gentianae 50g, Radix Cynanchi Paniculati 30g, Weng Bo 30g, Fructus Gardeniae 30g, Aspongopus 20g, Rhizoma Et Radix Notopterygii 20g, Rhizoma Curcumae Longae 20g, Borneolum Syntheticum 12g.
Claims (2)
1. treat a medicine for knee osteoarthritis, it is characterized in that it is to be made up of following raw material medicaments:
Radix seu Folium Rubi Pinfaensis 40-60 part, tree dish 30-50 part, Radix Gentianae 30-50 part, Radix Cynanchi Paniculati 20-30 part, Weng Bo 20-30 part, Fructus Gardeniae 20-30 part, Aspongopus 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Rhizoma Curcumae Longae 10-20 part, Borneolum Syntheticum 8-12 part.
2. medicine according to claim 1, is characterized in that it is to be made up of following raw material medicaments:
50 parts of Radix seu Folium Rubi Pinfaensis, 40 parts of dishes of tree, 40 parts of Radix Gentianae, 25 parts of Radix Cynanchi Paniculatis, 25 parts of Weng Bo, 25 parts of Fructus Gardeniaes, 15 parts of Aspongopuss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts, Rhizoma Curcumae Longae, 10 parts of Borneolum Syntheticums.
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| CN201410061359.XA CN103768538B (en) | 2014-02-24 | 2014-02-24 | A kind of medicine for the treatment of knee osteoarthritis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327144A (en) * | 2015-11-24 | 2016-02-17 | 李玲亮 | Traditional Chinese medicine for treating knee osteoarthritis |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196948A (en) * | 1998-03-04 | 1998-10-28 | 刘煌清 | Full presciption medicine for treating rheumatism disease |
| CN101721537A (en) * | 2009-12-25 | 2010-06-09 | 黄毅 | Traditional Chinese medicine for treating rheumatic and rheumatoid arthritis |
| CN102178759A (en) * | 2011-04-21 | 2011-09-14 | 张庆珍 | Traditional Chinese medicine composition for treating rheumatism and preparation method of composition |
| CN102727833A (en) * | 2012-07-12 | 2012-10-17 | 李琦 | Plaster for treating rheumatoid bone disease |
-
2014
- 2014-02-24 CN CN201410061359.XA patent/CN103768538B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196948A (en) * | 1998-03-04 | 1998-10-28 | 刘煌清 | Full presciption medicine for treating rheumatism disease |
| CN101721537A (en) * | 2009-12-25 | 2010-06-09 | 黄毅 | Traditional Chinese medicine for treating rheumatic and rheumatoid arthritis |
| CN102178759A (en) * | 2011-04-21 | 2011-09-14 | 张庆珍 | Traditional Chinese medicine composition for treating rheumatism and preparation method of composition |
| CN102727833A (en) * | 2012-07-12 | 2012-10-17 | 李琦 | Plaster for treating rheumatoid bone disease |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327144A (en) * | 2015-11-24 | 2016-02-17 | 李玲亮 | Traditional Chinese medicine for treating knee osteoarthritis |
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