CN103760374A - Reaction cup for chemiluminescent immunoassay detection - Google Patents
Reaction cup for chemiluminescent immunoassay detection Download PDFInfo
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- CN103760374A CN103760374A CN201310501165.2A CN201310501165A CN103760374A CN 103760374 A CN103760374 A CN 103760374A CN 201310501165 A CN201310501165 A CN 201310501165A CN 103760374 A CN103760374 A CN 103760374A
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- immune assay
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Abstract
The invention provides a reaction cup for chemiluminescent immunoassay detection. The reaction cup comprises a cup body (1), a cup edge (2) and liquid-collecting grooves (3) which are integrated into a whole, and is characterized in that the cup body (1) is of an inverted trapezoidal hollow-cavity shell structure, the top of the cup body (1) is provided with a rectangular opening, and the inner wall of the bottom of the cup body (1) is provided with an arc-shaped curved-surface groove; the cup edge (2) is connected with the top of the cup body (1) and extends outwards in a manner of being parallel to a plane where the top of the cup body (1) is arranged, and the cup edge (2) is provided with the liquid-collecting grooves (3). The bottom of the cup body (1) is of the arc-shaped curved-surface structure, so that generation of air bubbles during addition of a to-be-tested agent can be reduced; with the design of the cup edge (2), stability of the reaction cup in a transmission process is improved, and the to-be-tested agent is avoided from overflowing; and at the same time, the liquid-collecting grooves (3) can collect a part of overflowed to-be-tested agent, and pollution to an instrument is reduced. The whole reaction cup is in an integrated design, and is easy to process and low in manufacturing cost.
Description
Technical field
The present invention relates to a kind of reaction cup, be specially the reaction cup that a kind of chemiluminescence immune assay detects use.
Background technology
In recent years, the range of application of Full-automatic tube-type chemiluminescence immunoassay detector is more and more wider, just progressively replace semi-automatic product and board-like enzyme mark product, become the leading products in immune field, owing in testing process, test agent stirring, the light transmission etc. that holds the reaction cup of test agent being had relatively high expectations, simultaneous reactions cup easily causes the situations such as the excessive pollution instrument of reagent while moving under guide rail effect, therefore need carry out special processing to reaction cup.
The disclosed a kind of composite reaction cup of patent 200680027159.6, have and shorten sample mixing time, the advantages such as impact of inhibition external light source on measurement result, but because it is assembled state, processing technology is had relatively high expectations, simultaneously owing to there being a plurality of turnings in its cup, easily make sample produce bubble when stirring, thereby affect the problems such as measurement result.In patent 200710151356.5, disclosed reaction cup has the advantages such as stirring efficiency that prevent that liquid is excessive in reaction cup, improve liquid, but also exist and need to additionally set up mechanical hook-up and make reaction cup inclination certain angle, just can avoid the shortcoming of the generation of bubble.
Summary of the invention
The deficiency existing for existing reaction cup, the invention provides the reaction cup that a kind of chemiluminescence immune assay detects use, comprise integrated cup 1, cup along 2 with intercepting basin 3, it is characterized in that, the hollow shell body structure that described cup 1 is inverted trapezoidal, rectangular aperture is established at described cup 1 top, and described cup 1 bottom interior wall is established arc-shaped curved surface groove, described cup is along 2 connection described cup 1 tops and be parallel to described cup 1 place, top plane and stretch out, and described cup is along establishing described intercepting basin 3 on 2.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said cup 1 inwall corner all establishes circular chamfering.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said cup 1 cross section of inboard wall size is successively decreased to described cup 1 bottom along described cup 1 top.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said intercepting basin 3 is rectangular recess.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said intercepting basin 3 is parallel to the 1 outer wall setting of close described cup.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said intercepting basin 3 is 2 or 4.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said cup is rectangular configuration along 2.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said cup 1 wall adopts trnaslucent materials.
Preferably, described a kind of chemiluminescence immune assay detects the reaction cup of use, and wherein said cup 1 inwall is done hydrophobicity and processed.
A kind of chemiluminescence immune assay provided by the invention detects the reaction cup of use, and its advantage is:
1) cup 1 bottom interior wall is arc-shaped curved surface structure, can effectively reduce the generation of bubble while adding test agent; 2) cup 1 is inverted trapezoidal structure wide at the top and narrow at the bottom, effectively prevents test agent overflowing in transmitting procedure; 3) cup stretches out along 2, is convenient to the smooth transport of mechanically actuated and reaction cup; 4) design of intercepting basin 3 can be collected excessive test agent, avoids polluting instrument component; 5) cup 1 adopts symmetrical structure, when carrying out optical measurement, can its direction not distinguished, and has reduced the complexity of measuring system, has improved stability; 6) integral body of the present invention is the integrated design, easily processing and low cost of manufacture.
Accompanying drawing explanation
Fig. 1 is the side view that a kind of chemiluminescence immune assay that the present invention proposes detects the reaction cup of use.
Fig. 2 is the vertical view that a kind of chemiluminescence immune assay that the present invention proposes detects the reaction cup of use.
embodiment
Below in conjunction with accompanying drawing, the present invention is described in further detail, to make those skilled in the art can implement according to this with reference to instructions word.
Please refer to Fig. 1, the invention provides the reaction cup that a kind of chemiluminescence immune assay detects use, comprise integrated cup 1, cup along 2 with intercepting basin 3, it is characterized in that, the hollow shell body structure that described cup 1 is inverted trapezoidal, rectangular aperture is established at described cup 1 top, and described cup 1 bottom interior wall is established arc-shaped curved surface groove, described cup is along 2 connection described cup 1 tops and be parallel to described cup 1 place, top plane and stretch out, and described cup is along establishing described intercepting basin 3 on 2.
In the present invention,
Cup 1 inwall corner all establishes circular chamfering, and cup 1 cross section of inboard wall size is successively decreased to described cup 1 bottom along described cup 1 top.
Cup is rectangular configuration along 2.
Cup 1 wall adopts trnaslucent materials, and inwall is done hydrophobicity processing.
The course of work that a kind of chemiluminescence immune assay provided by the invention detects the reaction cup of use is: the cup of reaction cup, along 2, can utilize connecting gear, firm reaction cup is sent to sample application zone, educates the position that warm area, cleaning area, measurement zone etc. need.In transport process, because reaction cup is inverted trapezoidal structure wide at the top and narrow at the bottom, therefore the suffered pressure in bottom is greater than top pressure, can effectively slow down liquid due to overflowing that the vibration of reaction cup causes, cup can avoid test agent to drop on instrument along 2 design as far as possible simultaneously, pollute instrument, and can the test agent of overflowing be collected by intercepting basin 3.
Cup 1 bottom is arc-shaped curved surface structure, when carrying out application of sample, sample needle is first placed in needle body slightly high-order bit, cup 1 bottom, then liquid injection is gone out, and detecting liquid level parts are housed on sample needle, rising along with liquid, sample needle also constantly rises, and due to the existence of cambered surface, can slow down the impact of flow rate of liquid, reduce greatly the possibility that produces bubble, be conducive to the accuracy of final detection result.
When reaction cup is when carrying out optical measurement, this reaction cup is placed in to one and measures darkroom, and required exciting liquid is injected in reaction cup, material in reaction cup is because chemical action starts to carry out autoluminescence, detector is placed near the medium position outside reaction cup, and because cup is translucent, front and back are also symmetrical, therefore the direction position of reaction cup does not affect test result, has reduced the complexity of test macro.
Cup 1 width can be according to width setting between guide rail, cup can suitably be widened according to guide rail width along 2 width, be conducive to the stability of reaction cup in moving process, and can avoid test agent to drop on instrument, pollute instrument, simultaneously cup can be done the bending that radian is small along 2, and intercepting basin 3 positions, top are made as to lowest part, the recovery of the test agent that is conducive to overflow.
Although embodiment of the present invention are open as above, but it is not restricted to listed utilization in instructions and embodiment, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other modification, therefore do not deviating under the universal that claim and equivalency range limit, the present invention is not limited to specific details and illustrates here and the legend of describing.
Claims (9)
1. a chemiluminescence immune assay detects the reaction cup of use, comprise that integrated cup (1), cup are along (2) and intercepting basin (3), it is characterized in that, the hollow shell body structure that described cup (1) is inverted trapezoidal, rectangular aperture is established at described cup (1) top, and described cup (1) bottom interior wall is established arc-shaped curved surface groove, described cup connects described cup (1) top and is parallel to described cup (1) place, top plane along (2) and stretches out, and described cup is along establishing described intercepting basin (3) on (2).
2. a kind of chemiluminescence immune assay according to claim 1 detects the reaction cup of use, it is characterized in that, described cup (1) inwall corner all establishes circular chamfering.
3. a kind of chemiluminescence immune assay according to claim 1 detects the reaction cup of use, it is characterized in that, described cup (1) cross section of inboard wall size is successively decreased bottom along described cup (1) top to described cup (1).
4. a kind of chemiluminescence immune assay according to claim 1 detects the reaction cup of use, it is characterized in that, described intercepting basin (3) is rectangular recess.
5. a kind of chemiluminescence immune assay according to claim 4 detects the reaction cup of use, it is characterized in that, described intercepting basin (3) is parallel to close described cup (1) outer wall setting.
6. a kind of chemiluminescence immune assay according to claim 5 detects the reaction cup of use, it is characterized in that, described intercepting basin (3) is 2 or 4.
7. a kind of chemiluminescence immune assay according to claim 1 detects the reaction cup of use, it is characterized in that, described cup is rectangular configuration along (2).
8. a kind of chemiluminescence immune assay according to claim 1 detects the reaction cup of use, it is characterized in that, described cup (1) wall adopts trnaslucent materials.
9. a kind of chemiluminescence immune assay according to claim 8 detects the reaction cup of use, it is characterized in that, described cup (1) inwall is done hydrophobicity and processed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310501165.2A CN103760374B (en) | 2013-10-23 | 2013-10-23 | The reaction cup that a kind of chemiluminescence immune assay detects |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310501165.2A CN103760374B (en) | 2013-10-23 | 2013-10-23 | The reaction cup that a kind of chemiluminescence immune assay detects |
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| Publication Number | Publication Date |
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| CN103760374A true CN103760374A (en) | 2014-04-30 |
| CN103760374B CN103760374B (en) | 2015-09-02 |
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| CN201310501165.2A Active CN103760374B (en) | 2013-10-23 | 2013-10-23 | The reaction cup that a kind of chemiluminescence immune assay detects |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108107227A (en) * | 2018-02-09 | 2018-06-01 | 深圳市活水床旁诊断仪器有限公司 | A kind of chemiluminescence immune assay chip cartridges and operating method |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3580686A (en) * | 1969-03-17 | 1971-05-25 | Coulter Electronics | Vessel having intersample anticontamination construction |
| CN1115027A (en) * | 1993-12-28 | 1996-01-17 | 东亚医用电子株式会社 | Cuvette |
| US20050271550A1 (en) * | 2004-06-08 | 2005-12-08 | Mark Talmer | Tapered cuvette and method of collecting magnetic particles |
| CN101228430A (en) * | 2005-07-27 | 2008-07-23 | 希森美康株式会社 | Cuvette |
| CN202372516U (en) * | 2011-08-16 | 2012-08-08 | 杨晓勇 | Reaction cup applied to full-automatic chemiluminescent analyzer |
| EP2607883A1 (en) * | 2011-12-19 | 2013-06-26 | F. Hoffmann-La Roche AG | System for photometric measurement of liquids |
| CN203490235U (en) * | 2013-10-23 | 2014-03-19 | 中国科学院苏州生物医学工程技术研究所 | Reaction cup for chemiluminiscence immune assay detection |
-
2013
- 2013-10-23 CN CN201310501165.2A patent/CN103760374B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3580686A (en) * | 1969-03-17 | 1971-05-25 | Coulter Electronics | Vessel having intersample anticontamination construction |
| CN1115027A (en) * | 1993-12-28 | 1996-01-17 | 东亚医用电子株式会社 | Cuvette |
| US20050271550A1 (en) * | 2004-06-08 | 2005-12-08 | Mark Talmer | Tapered cuvette and method of collecting magnetic particles |
| CN101228430A (en) * | 2005-07-27 | 2008-07-23 | 希森美康株式会社 | Cuvette |
| CN202372516U (en) * | 2011-08-16 | 2012-08-08 | 杨晓勇 | Reaction cup applied to full-automatic chemiluminescent analyzer |
| EP2607883A1 (en) * | 2011-12-19 | 2013-06-26 | F. Hoffmann-La Roche AG | System for photometric measurement of liquids |
| CN203490235U (en) * | 2013-10-23 | 2014-03-19 | 中国科学院苏州生物医学工程技术研究所 | Reaction cup for chemiluminiscence immune assay detection |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108107227A (en) * | 2018-02-09 | 2018-06-01 | 深圳市活水床旁诊断仪器有限公司 | A kind of chemiluminescence immune assay chip cartridges and operating method |
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| CN103760374B (en) | 2015-09-02 |
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Application publication date: 20140430 Assignee: Suzhou Guoke Junhao Biotechnology Co., Ltd. Assignor: Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Contract record no.: 2018320010060 Denomination of invention: Reaction cup for chemiluminescent immunoassay detection Granted publication date: 20150902 License type: Exclusive License Record date: 20181126 |
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