CN103751512A - Traditional Chinese medicament for treating diabetes - Google Patents

Abstract

The invention discloses a traditional Chinese medicament for treating diabetes. The medicament comprises the following Chinese medicinal components in percentage by weight: 12 to 13.6 percent of Radix Astragali, 12 to 13.6 percent of kudzu-vine root, 2.8 to 4.7 percent of dwarf lilyturf tuber, 2.8 to 4.7 percent of root of rehmannia, 3.8 to 5.2 percent of figwort root, 3.8 to 5.2 percent of glossy privet fruit, 12 to 13.6 percent of pollen, 3.8 to 5.2 percent of Chinese yam, 3.8 to 5.2 percent of Ligusticum wallichii, 3.8 to 5.2 percent of safflower, 11 to 13.6 percent of root of red-rooted salvia, 9.5 to 11.8 percent of Chinese wolfberry, 3.8 to 5.2 percent of mulberry, 2.8 to 4.8 percent of cortex moutan and 2.8 to 4.7 percent of licorice. The traditional Chinese medicament is prepared by concentrating and extracting pure Chinese medicaments, effectively and radically treats patients with the diabetes, and prevents the generation and development of chronic complications of the diabetes. The medicament has 30 percent of functions of reducing blood sugar, and 70 percent of functions of resisting complications, and makes the patients with the diabetes return to life of normal people without avoiding certain food.

Description

A kind of Chinese medicine for the treatment of diabetes

Technical field

The present invention relates to technical field of Chinese medicines, be specially a kind of Chinese medicine for the treatment of diabetes.

Background technology

Diabetes are a kind of chronic disease, frequently-occurring disease, commonly encountered diseases, and in general population, sickness rate is very high, serious harm people's orthobiosis, to people, caused great harm, cause very large injury also to patient.Therefore the research of, actively developing diabetes has become a current important topic.The medicine for the treatment of diabetes is a lot of at present, Western medicine mainly contains the compositions such as insulin, for symptomatic treatment, good stabilizing blood sugar, and expense is higher, and have very large dependency after patient's use, main is that Western medicine can not well prevent and control complication, and the key of diabetes is exactly effectively to have controlled the generation of complication when having stablized blood glucose, such medicine is respond well medicine at last.Yet this point Western medicine do not accomplish, we can only control with Chinese medicine.Although Chinese medicine does not have Western medicine blood sugar lowering speed fast, Chinese medicine be the liver of repairing human body, renal function for basic, thereby reach the object of controlling blood glucose, could well control the state of an illness of diabetes like this, make its no longer past downward-extension.

Insulin resistant ubiquity in type 2 diabetes mellitus is found in research, almost accounts for more than 90%.

In after making a definite diagnosis 5 years of type 1 diabetes patient, seldom there is the appearance of chronic complicating diseases.

Type 2 diabetes mellitus patient had just had chronic complicating diseases to occur before making a definite diagnosis.According to statistics, have the 50% new type 2 diabetes mellitus patient who diagnoses to have one or more chronic complicating diseases, some patient just finds to suffer from diabetes because of complication.Diabetic complication shows as: the diseases such as retinopathy, nephropathy and neurological disorder and arteriosclerosis, the disastrous effect that in blood, superfluous glucose corrodes whole body organ and tissue thereof gradually.

Therefore, the Drug therapy of diabetes should be focused on improving insulin resistant for its cause of disease, and the protection to Pancreatic beta cells function, must select the medicine that can improve insulin resistant.

Summary of the invention:

The technical problem to be solved in the present invention is to provide a kind of Chinese medicine and preparation method thereof for type 2 diabetes mellitus, solve the difficulty that patient can also continue to take medicine the in the situation that of liver, impaired renal function, after taking medicine, not only do not stimulate liver, renal function, can also remove to the full extent to repair impaired liver, renal function, thereby reach stabilizing blood sugar, effectively prevent and control the generation of complication.

For solving the problems of the technologies described above the technical solution used in the present invention, be:

Treat a Chinese medicine for diabetes, comprise the Chinese medicine ingredients of following percentage by weight:

The Radix Astragali: 12%～13.6%;

Radix Puerariae: 12%～13.6%;

Radix Ophiopogonis: 2.8%～4.7%;

The Radix Rehmanniae: 2.8%～4.7%;

Radix Scrophulariae: 3.8%～5.2%;

Fructus Ligustri Lucidi: 3.8%～5.2%;

Pollen: 12%～13.6%;

Rhizoma Dioscoreae: 3.8%～5.2%;

Rhizoma Chuanxiong: 3.8%～5.2%

Flos Carthami: 3.8%～5.2%;

Radix Salviae Miltiorrhizae: 11%～13.6%;

Fructus Lycii: 9.5%～11.8%;

Fructus Mori: 3.8%～5.2%;

Cortex Moutan: 2.8%～4.8%;

Radix Glycyrrhizae: 2.8%～4.7%.

As preferably, the Chinese medicine ingredients of percentage by weight:

The Radix Astragali: 12.5%;

Radix Puerariae: 12.5%;

Radix Ophiopogonis: 3.6%;

The Radix Rehmanniae: 3.6%;

Radix Scrophulariae: 4.25%;

Fructus Ligustri Lucidi: 4.25%;

Pollen: 12.5%;

Rhizoma Dioscoreae: 4.25%;

Rhizoma Chuanxiong: 4.25%;

Flos Carthami: 4.25%;

Radix Salviae Miltiorrhizae: 12.5%;

Fructus Lycii: 10%;

Fructus Mori: 4.25%;

Cortex Moutan: 3.7%;

Radix Glycyrrhizae: 3.6%.

The optional scope of other compositions:

The Radix Astragali: 12%;

Radix Puerariae: 12%;

Radix Ophiopogonis: 2.8%;

The Radix Rehmanniae: 2.8%;

Radix Scrophulariae: 3.8%;

Fructus Ligustri Lucidi: 3.8%;

Pollen: 12%;

Rhizoma Dioscoreae: 3.8%;

Rhizoma Chuanxiong: 3.8%;

Flos Carthami: 3.8%;

Radix Salviae Miltiorrhizae: 11%;

Fructus Lycii: 9.5%;

Fructus Mori: 3.8%;

Cortex Moutan: 2.8%;

Radix Glycyrrhizae: 2.8%.

Optional scope again:

The Radix Astragali: 13.6%;

Radix Puerariae: 13.6%;

Radix Ophiopogonis: 4.7%;

The Radix Rehmanniae: 4.7%;

Radix Scrophulariae: 5.2%;

Fructus Ligustri Lucidi: 5.2%;

Pollen: 13.6%;

Rhizoma Dioscoreae: 5.2%;

Rhizoma Chuanxiong: 5.2%;

Flos Carthami: 5.2%;

Radix Salviae Miltiorrhizae: 13.6%;

Fructus Lycii: 11.8%;

Fructus Mori: 5.2%;

Cortex Moutan: 4.8%;

Radix Glycyrrhizae: 4.7%;

According to drug matching, dosage is moderate, monarch, minister in composition, helps, makes respectively to execute its effect, and each is mended, and it is short, interacts, and can reach optimum therapeuticing effect, equal like this can effectively control and stabilizing blood sugar.

In composition, take the Radix Astragali, Radix Puerariae, Radix Ophiopogonis organizes medicine as monarch.There is air making-up and spleen enlivening, inducing diuresis to remove edema, promoting the production of body fluid to quench thirst, nourishing YIN and moistening the lung, the effect of reinforcing stomach reg fluid.The Radix Astragali hypoglycemia that can raise, reduces hyperglycemia, strengthens myocardial contraction, protection cardiovascular system, and arrhythmia, coronary artery dilator and peripheral blood vessel, reduce blood pressure, and blood fat reducing, defying age, the effect such as protects the liver; Radix Puerariae enters taste warp, can expand arteria coronaria blood vessel and cerebrovascular, increases coronary flow and cerebral blood flow, reduces myocardial oxygen consumption, increases oxygen supply, and has slight hypoglycemic activity; Enter stomach, lung, heart channel Radix Ophiopogonis, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire.Can heighten immunologic function, strengthen pituitary adrenal system effect, improve organism adaptation.

Take the Radix Rehmanniae, Radix Scrophulariae, Fructus Ligustri Lucidi, pollen, Rhizoma Dioscoreae is ministerial drug, the effects such as YIN nourishing and the production of body fluid promoting, nourishing the liver and kidney, promoting the production of body fluid to quench thirst, spleen reinforcing lung kidney.The Radix Rehmanniae has hormonal regulation effect, can adjust carbohydrate metabolism disturbance.Radix Scrophulariae and Radix Rehmanniae mutual reinforcement between energy YIN nourishing and the production of body fluid promoting, and have the effects such as antiinflammatory, calmness.And Fructus Ligustri Lucidi has heart tonifying, diuresis, blood sugar lowering and hepatoprotective effect.Pollen enters lung, stomach warp, and glycopenia activity falls in the non-osmosizing portion potential energy of pollen water extract.Rhizoma Dioscoreae enters spleen, lung, kidney channel, has supplementing QI and nourishing YIN, the effect of spleen reinforcing lung kidney.And can play good hypoglycemic activity.Above five ministerial drugs have and fall hypoglycemic effect, go, with exopathogen, to radically reform.

Take Flos Carthami, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Fructus Lycii is the effects such as adjuvant drug, promoting blood circulation to restore menstrual flow, blood-activating and qi-promoting, nourishing the liver and kidney.Flos Carthami enters the heart, Liver Channel.Flos Carthami can be protected and improve myocardial ischemia, dwindles myocardial infarct size, expansion peripheral vessels, the effect reducing blood pressure.Rhizoma Chuanxiong enters liver, gallbladder, pericardium channel.There is coronary artery dilator, increase coronary artery blood flow, improve myocardium blood oxygen supply, and reduce the myocardium effects such as oxygen consumption.Radix Salviae Miltiorrhizae enters the heart, pericardium, Liver Channel.Radix Salviae Miltiorrhizae has the effect that improves renal function, protection Ischemic kieney injury, has the effect of antiinflammatory.Fructus Lycii enters liver, kidney channel.Fructus Lycii has facilitation to immunity, has immunoregulation effect simultaneously, also has defying age, mutation, blood fat reducing, protects the liver and anti-fatty liver, blood sugar lowering, hypotensive activity.

With Fructus Mori, Cortex Moutan, Radix Glycyrrhizae, for making medicine group, all medicines of balance, alleviate the property of medicine, whole standardized, improve curative effect.Fructus Mori enters liver, kidney channel.There is promoting the production of body fluid to quench thirst, the thirsty effect of Tianjin wound.Cortex Moutan enters the heart, liver, kidney channel.There is the effect of blood circulation promoting and blood stasis dispelling.Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, and separate the poison of hundred medicines.

Monarch of the present invention, minister, help, make respectively to execute its effect; each is mended, and it is short; interact; there is the effect of obvious reparation liver function and renal function; reached and fundamentally repaired human liver, renal function; control the object of blood glucose, because the protective effect to other organ of human body, thereby complication effectively resisted.Suppress the generation of virus and inflammation, effectively reduce blood glucose, reach the object for the treatment of both the principal and secondary aspects of a disease, effect is very obvious, and treatment cycle is short and relapse rate is low.

Preparation clinical test results of the present invention is as follows:

Through 220 examples, observe, this 220 routine case is divided into 2 groups at random, the wherein capsule treatment for the treatment of diabetes of the present invention for 120 examples, gliclazide western drug treatment for 100 examples.Treatment is front and start rear blood glucose of every 1～2 weekly check, glucose in urine to observe its variation, require patient must adhere to taking medicine one more than the course for the treatment of, it within two months, is a course for the treatment of, during treatment, continue to keep diet and physical exertion constant, forbid adding other hypoglycemic in, western drug, viewing duration requires suitably to keep on a diet, and takes continuously we after two courses for the treatment of, and total effective rate reaches 95%.

Treatment diabetes capsule agent group of the present invention (120), each oral 2～3, every day 3, this, two months be a course for the treatment of.

Gliclazide treatment group (100 people): each oral 40mg, every day 2～3 times.

2 group of 220 routine case treatment Comparison of therapeutic is as following table:

Beneficial effect of the present invention is: pure traditional Chinese drug inspissation extraction forms, and makes diabetics obtain treatment timely and effective and fundamentally, the generation of prevent diabetes chronic complicating diseases and development.This medicine major function is 30% blood sugar lowering, 70% antagonism complication.Do not need dieting, make diabetics return normal person's life.

The specific embodiment

Embodiment: get 30 parts of the Radixs Astragali, 30 parts of Radix Puerariaes, 10 parts of Radix Ophiopogonis, 20 parts of Fructus Lyciis, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts, Radix Glycyrrhizae.First medical material is washed, then by the Radix Astragali, Radix Puerariae, Radix Ophiopogonis, Fructus Lycii, Radix Salviae Miltiorrhizae, six medical material natural dryings of Radix Glycyrrhizae or oven dry, pulverize as 200--300 order medicated powder, mix all medicated powder, the ethanol extraction that is 75% by concentration 1--5 time, extraction time is 20 hours, filter, filtrate merges, concentrated, dry, obtains activity extract; Other medical material is put into extractor, soaks 35--50 minute, decocts for the first time 3～4 hours, leaches; Decoct for the second time 2～2.5 hours, leach; Twice filtrate is merged, obtain extract, and then add the Radix Astragali, Radix Puerariae, Radix Ophiopogonis, Fructus Lycii, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae activity extract, stir, it is 1.50-1.55 thick paste shape that filtrate is condensed into density, dries, is ground into 200--300 order fine powder, obtains powder.With common process, make capsule.Usage is every day 3 times, 0.08g, in ante cibum, meal or one after each meal can.

By above prescription, take medicine, the capsule formulation forming with high-tech means height concentrated extract, has significant effect for the treatment of diabetes.

Concrete case is as follows:

1, patient's name: Tian Cuilian, 51 years old age, obtain medical history 5 years, once used the Western medicine such as metformin, within 2008, took this formula, and from initial monthly 4.8g, started to take, to monthly 0.16g subsequently, some months is just taken 0.16g now, and blood glucose can also steadily be controlled at below 7 like this, and any complication does not appear in medication so long.

2, patient's name: Yao Xiuying, 56 years old age, obtain medical history 6-7, once used the Western medicine such as diabetes pill, diamicron, although glycemic control is fine, there is cataract seldom in eye, illustrates that Western medicine is to not well prevention and control of complication.Within 2008, take this formula, take at first 9.6g, just controlled well blood glucose, taken this formula two months, from 9.6g monthly, reduced to monthly 7g, by the not only not development of bimestrial time eye cataract, and in minimizing slowly, by the time of 2 years, monthly take now 2.4g, blood glucose can also be controlled at below 6, and does not occur any complication.

The foregoing is only embodiments of the invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in claim scope of the present invention.

Claims (2)

1. a Chinese medicine for the treatment of diabetes, is characterized in that: the Chinese medicine ingredients that comprises following percentage by weight:

The Radix Astragali: 12%～13.6%;

Radix Puerariae: 12%～13.6%;

Radix Ophiopogonis: 2.8%～4.7%;

The Radix Rehmanniae: 2.8%～4.7%;

Radix Scrophulariae: 3.8%～5.2%;

Fructus Ligustri Lucidi: 3.8%～5.2%;

Pollen: 12%～13.6%;

Rhizoma Dioscoreae: 3.8%～5.2%;

Rhizoma Chuanxiong: 3.8%～5.2%

Flos Carthami: 3.8%～5.2%;

Radix Salviae Miltiorrhizae: 11%～13.6%;

Fructus Lycii: 9.5%～11.8%;

Fructus Mori: 3.8%～5.2%;

Cortex Moutan: 2.8%～4.8%;

Radix Glycyrrhizae: 2.8%～4.7%.

2. a kind of Chinese medicine for the treatment of diabetes according to claim 1, is characterized in that: the Chinese medicine ingredients that comprises following percentage by weight:

The Radix Astragali: 12.5%;

Radix Puerariae: 12.5%;

Radix Ophiopogonis: 3.6%;

The Radix Rehmanniae: 3.6%;

Radix Scrophulariae: 4.25%;

Fructus Ligustri Lucidi: 4.25%;

Pollen: 12.5%;

Rhizoma Dioscoreae: 4.25%;

Rhizoma Chuanxiong: 4.25%;

Flos Carthami: 4.25%;

Radix Salviae Miltiorrhizae: 12.5%;

Fructus Lycii: 10%;

Fructus Mori: 4.25%;

Cortex Moutan: 3.7%;

Radix Glycyrrhizae: 3.6%.