CN103751357B - A kind of Chinese medicine composition for the treatment of spleen-deficient colitis - Google Patents
A kind of Chinese medicine composition for the treatment of spleen-deficient colitis Download PDFInfo
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- CN103751357B CN103751357B CN201410017706.9A CN201410017706A CN103751357B CN 103751357 B CN103751357 B CN 103751357B CN 201410017706 A CN201410017706 A CN 201410017706A CN 103751357 B CN103751357 B CN 103751357B
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- 239000003814 drug Substances 0.000 title claims abstract description 50
- 210000000952 spleen Anatomy 0.000 title claims abstract description 28
- 206010009887 colitis Diseases 0.000 title claims abstract description 23
- 239000000203 mixture Substances 0.000 title claims abstract description 23
- 230000002950 deficient Effects 0.000 title claims abstract description 17
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 8
- 239000009636 Huang Qi Substances 0.000 claims abstract description 7
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 7
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 5
- 230000001225 therapeutic effect Effects 0.000 abstract description 4
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 238000007670 refining Methods 0.000 abstract description 2
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000013872 defecation Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 208000019790 abdominal distention Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010060891 General symptom Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 206010019842 Hepatomegaly Diseases 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
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- 230000035568 catharsis Effects 0.000 description 1
- UNJFKXSSGBWRBZ-BJCIPQKHSA-N ceftibuten Chemical compound S1C(N)=NC(C(=C\CC(O)=O)\C(=O)N[C@@H]2C(N3C(=CCS[C@@H]32)C(O)=O)=O)=C1 UNJFKXSSGBWRBZ-BJCIPQKHSA-N 0.000 description 1
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- NPGNOVNWUSPMDP-UTEPHESZSA-N chembl1650818 Chemical compound N(/[C@H]1[C@@H]2N(C1=O)[C@H](C(S2)(C)C)C(=O)OCOC(=O)C(C)(C)C)=C\N1CCCCCC1 NPGNOVNWUSPMDP-UTEPHESZSA-N 0.000 description 1
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- LZCOQTDXKCNBEE-IKIFYQGPSA-N methscopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3[N+]([C@H](C2)[C@@H]2[C@H]3O2)(C)C)=CC=CC=C1 LZCOQTDXKCNBEE-IKIFYQGPSA-N 0.000 description 1
- 229960001383 methylscopolamine Drugs 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229960004212 pivmecillinam Drugs 0.000 description 1
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- 208000012271 tenesmus Diseases 0.000 description 1
- 229960004659 ticarcillin Drugs 0.000 description 1
- OHKOGUYZJXTSFX-KZFFXBSXSA-N ticarcillin Chemical compound C=1([C@@H](C(O)=O)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)C=CSC=1 OHKOGUYZJXTSFX-KZFFXBSXSA-N 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Abstract
The invention belongs to technical field of Chinese medicines.The object of the invention is according to the understanding mechanism of the traditional Chinese medical science to colitis one disease, a kind of Chinese medicine composition for the treatment of spleen-deficient colitis is provided, it is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 10-15, Radix Paeoniae Alba 18-22, Fructus Aurantii 8-12, Herba Taraxaci 28-32, Radix Glycyrrhizae 2-6, Radix Saposhnikoviae 8-12, Rhizoma Atractylodis Macrocephalae 8-12, Radix Astragali 8-12, Poria 12-18.The Chinese medicine composition refining formula that this invention provides, compatibility science, through tcm clinical practice application, cause colitis one disease to have good therapeutic effect to spleen-deficient, through statistics, its effective percentage reaches more than 90%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of spleen-deficient colitis.
Background technology
Colitis, also known as nonspecific ulcerative colitis, how slow onset is, and state of an illness weight differs, and diarrhoea is cardinal symptom, discharges bloody purulent stool, mucosanguineous feces or hemafecia, often accompany tenesmus, have the feature of stomachache → awareness of defecation → defecation → alleviation.Colitis stomachache mostly generally is dull pain or angor, is often positioned at left lower quadrant or lower abdomen.Other performance has inappetence, abdominal distention, Nausea and vomiting and hepatomegaly etc.; Left lower quadrant can have tenderness, sometimes can touch the colon of spasm.Common General Symptoms is become thin, weak, heating, anemia etc.The Clinical typing of colitis in the traditional Chinese medical science mainly contains 3 kinds, diarrhoeal, constipation type and alternating diarrhea and constipation type.In diagnostic procedure, the pathogenic factor of 3 kinds of typings with insufficiency of the spleen cause let out comparatively common.
Summary of the invention
The object of the invention is according to the understanding mechanism of the traditional Chinese medical science to colitis one disease, provide that a kind of compatibility science, prescription are easy, the Chinese medicine composition of the treatment spleen-deficient colitis with good therapeutic effect.
The technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of spleen-deficient colitis, is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 10-15, Radix Paeoniae Alba 18-22, Fructus Aurantii 8-12, Herba Taraxaci 28-32, Radix Glycyrrhizae 2-6, Radix Saposhnikoviae 8-12, Rhizoma Atractylodis Macrocephalae 8-12, Radix Astragali 8-12, Poria 12-18.
The instructions of taking of above-mentioned Chinese medicine composition is: after getting the raw material Chinese medicine mixing of above-mentioned weight proportion, adopt the mode of traditional fried Chinese medicine to get its medicine juice, every day one is secondary, and a point morning and evening takes for twice, within 7th, is a course for the treatment of.
Spleen is dependent territory in the five elements, belongs to the Zhiyin in the moon in organ yin-yang.The spleen has the function to transport and transform nutrients, and system blood, the lucid yang sending up, defeated cloth essence of water and grain, is " source of generating QI and blood ".After human body birth, each internal organs organ all relies on spleen institute, and to change raw essence of water and grain foster to moisten, therefore title spleen is " the foundation of acquired constitution ".Ferritic is insufficiency of the spleen to be caused damp and occupies for a long time, damage temper, causes the source of vital function not enough.Biochemical not enough, the raw wood of water, the wooden strongly fragrant stagnation of QI, disgruntled raw wind, the main catharsis of wind, it is eclipsed to be born in then blood depletion, and then have loose bowels under being born in more than, that therefore treats spleen-deficient colitis is spleen invigorating dispelling wind at all.In Chinese medicine composition provided by the present invention, get Poria and let out Middle Palace damp; Extracting liquorice, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Radix Astragali air making-up and spleen enlivening, to hold up spleen sun; Get Radix Bupleuri, the Radix Paeoniae Alba, Radix Saposhnikoviae under-stocking fresh breeze; Herba Taraxaci heat-clearing and toxic substances removing in addition.Above-mentioned all medicines share, and let out spleen and wet, and help spleen sun, dispelling wind evil, and Middle Palace is then wooden quiet wind breath, colitis so that recovery from illness by force.The Chinese medicine composition refining formula that this invention provides, compatibility science, through tcm clinical practice application, cause colitis one disease to have good therapeutic effect to spleen-deficient, through statistics, its effective percentage reaches more than 90%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for spleen-deficient colitis, it is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 12g, Radix Paeoniae Alba 15g, Fructus Aurantii 10g, Herba Taraxaci 30g, Radix Glycyrrhizae 3g, Radix Saposhnikoviae 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Astragali 10g, Poria 15g.
Embodiment 2
Treat a Chinese medicine composition for spleen-deficient colitis, it is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 10g, Radix Paeoniae Alba 22g, Fructus Aurantii 8g, Herba Taraxaci 32g, Radix Glycyrrhizae 2g, Radix Saposhnikoviae 12g, Rhizoma Atractylodis Macrocephalae 8g, Radix Astragali 12g, Poria 12g.
Embodiment 3
Treat a Chinese medicine composition for spleen-deficient colitis, it is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 15g, Radix Paeoniae Alba 18g, Fructus Aurantii 12g, Herba Taraxaci 28g, Radix Glycyrrhizae 6g, Radix Saposhnikoviae 8g, Rhizoma Atractylodis Macrocephalae 12g, Radix Astragali 8-g, Poria 18g.
Clinical verification is as follows:
Select 60 routine spleen-deficient colitis disease, age 18-45 year, symptom is as follows: diarrhoea, stomachache, the disease such as constipation has abdominal distention feeling of fullness concurrently, limb of becoming thin is weary, rushes down time half congealed during stool, delay repeatedly, aqueous-grainy diarrhea, slightly enter greasy food then times of defecation increase, shallow complexion, tired, pale tongue with white fur, thready and weak pulse has slow pulse concurrently and delays, and above symptom can regard as spleen-deficient colitis.Above-mentioned patient is divided at random treatment by Chinese herbs group and western medicine group two groups, often organize 30 people, wherein treatment by Chinese herbs group adopts Chinese medicine composition provided by the invention, after being mixed in proportion by raw material Chinese medicine provided by the invention, traditionally the mode of fried Chinese medicine is got it and is got its medicine juice, every day one is secondary, divide and sooner or later take for twice, 7 as a course for the treatment of; Western medical treatment group adopts oral or injection methscopolamine bromide, pivmecillinam, ticarcillin sodium, one or more in ceftibuten.Rehabilitation standard: treatment 1-2 week transference cure, 1 year afterwards pay a return visit without more repeatedly person be thorough rehabilitation.Statistical result is as follows:
Can be found out by above-mentioned statistics, fast for spleen-deficient colitis Western medicine traditional Chinese medicine composition for treating speed more provided by the invention in treatment speed, but the therapeutic effect of Chinese medicine composition provided by the invention to spleen-deficient colitis is more thorough.
Claims (1)
1. treat a Chinese medicine composition for spleen-deficient colitis, it is characterized in that: described Chinese medicine composition adopts the material medicine of following weight proportion to adopt the mode of conventional fried Chinese medicine to get its medicine juice to make: Radix Bupleuri 10-15, Radix Paeoniae Alba 18-22, Fructus Aurantii 8-12, Herba Taraxaci 28-32, Radix Glycyrrhizae 2-6, Radix Saposhnikoviae 8-12, Rhizoma Atractylodis Macrocephalae 8-12, Radix Astragali 8-12, Poria 12-18.
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| CN201410017706.9A CN103751357B (en) | 2014-01-16 | 2014-01-16 | A kind of Chinese medicine composition for the treatment of spleen-deficient colitis |
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| CN201410017706.9A CN103751357B (en) | 2014-01-16 | 2014-01-16 | A kind of Chinese medicine composition for the treatment of spleen-deficient colitis |
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| CN103751357A CN103751357A (en) | 2014-04-30 |
| CN103751357B true CN103751357B (en) | 2016-03-23 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107260851B (en) * | 2017-06-14 | 2020-07-31 | 广州中医药大学第一附属医院 | Traditional Chinese medicine composition for treating deficiency constipation |
| CN114366795A (en) * | 2020-10-15 | 2022-04-19 | 石家庄以岭药业股份有限公司 | Traditional Chinese medicine composition and medicine for irritable bowel syndrome, and preparation method and application thereof |
Citations (5)
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| CN1231202A (en) * | 1998-01-17 | 1999-10-13 | 吴书西 | Traditional Chinese medicine preparation for treating colitis |
| CN101007155A (en) * | 2007-01-19 | 2007-08-01 | 广州陈李济药厂 | Gastric-dissolved and enteric-dissolved pills of traditional Chinese medicine capable of strengthening spleen and nourishing intestine and its preparation method |
| CN101129692A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating middle-jiaoenergy deficiency-cold type gastralgia |
| CN102100817A (en) * | 2010-11-29 | 2011-06-22 | 闫成秀 | Chinese medicinal preparation for treating infection of upper respiratory tracts |
| CN103054954A (en) * | 2012-12-28 | 2013-04-24 | 青岛爱维互动信息技术有限公司 | Traditional Chinese medicine composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101271054B1 (en) * | 2010-10-18 | 2013-07-26 | 동국대학교 경주캠퍼스 산학협력단 | Pharmaceutical composition for preventing and treating diseases related to renal failure containing extract from Salvia miltiorrhiza radix, Atractylodis macrocephalae rhizome, Polyporus, Poria, Pinelliae rhizome, Coptis rhizome and Rhei radix et rhizoma |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1231202A (en) * | 1998-01-17 | 1999-10-13 | 吴书西 | Traditional Chinese medicine preparation for treating colitis |
| CN101007155A (en) * | 2007-01-19 | 2007-08-01 | 广州陈李济药厂 | Gastric-dissolved and enteric-dissolved pills of traditional Chinese medicine capable of strengthening spleen and nourishing intestine and its preparation method |
| CN101129692A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating middle-jiaoenergy deficiency-cold type gastralgia |
| CN102100817A (en) * | 2010-11-29 | 2011-06-22 | 闫成秀 | Chinese medicinal preparation for treating infection of upper respiratory tracts |
| CN103054954A (en) * | 2012-12-28 | 2013-04-24 | 青岛爱维互动信息技术有限公司 | Traditional Chinese medicine composition |
Non-Patent Citations (1)
| Title |
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| 玉屏风散合四逆散治疗慢性结肠炎48例疗效观察;林志荣;《新中医》;19971231;第29卷(第7期);第35页左栏第3-4段，提要 * |
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