CN103751333A - Medicinal composition for treating burns and preparation method thereof - Google Patents
Medicinal composition for treating burns and preparation method thereof Download PDFInfo
- Publication number
- CN103751333A CN103751333A CN201310752028.6A CN201310752028A CN103751333A CN 103751333 A CN103751333 A CN 103751333A CN 201310752028 A CN201310752028 A CN 201310752028A CN 103751333 A CN103751333 A CN 103751333A
- Authority
- CN
- China
- Prior art keywords
- preparation
- pharmaceutical composition
- oleum
- brassicae campestris
- mel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a medicinal composition, and in particular relates to a medicinal composition for treating burns. The medicinal composition is prepared from the following bulk drugs: carbonized sanguisorba root, spatholobus suberctu, coptidis rhizome, polygonum cuspidatum, ginseng and honey. Clinical tests prove that the medicinal composition has a remarkable curative effect to burns, and can be used for effectively shortening the course of treatment.
Description
Technical field
The present invention relates to pharmaceutical composition, specifically, relate to a kind of pharmaceutical composition for the treatment of burn and preparation method thereof.
Background technology
Burn is to act on body and the acute injury that causes by various factorss such as physics, chemistry, lonizing radiation.The traditional Chinese medical science claims " baked wheaten cake skin ulcer ", " burn and scald ", and its origin cause of formation is due to flame, and the factors such as hot water cause human body skin and subcutaneous tissue to be burnt, and fur is not deposited, sepage stream Tianjin, usur skin.Gently affect attractive in appearancely, heavy cause multiple General Symptoms, the order of severity of burn depends on scope and the degree of depth of wounded tissue.
Western medical treatment burn, hinder face through cleaning, then wound is carried out adding medicine to after the processing of downright bad muscular tissue and rigorous sterilization, then wrapping.Doctor trained in Western medicine does not advocate to hinder face medicine-feeding, mainly take innerlich anwenden as main, hinders face and with any medicine, directly processes hardly.But this method seems science, in fact effect is not ideal, and cost is extremely expensive.And the traditional Chinese medical science is when treating burn, to add medicine to immediately, pain relieving at once, alleviates and eliminates the pain of injury, fully stimulates the regeneration capacity of human body cell by external used medicine, impels muscular tissue to regrow.But its formula is complicated, effect is still undesirable, and treatment is longer the course for the treatment of.
Summary of the invention
In order to solve problems of the prior art, the object of this invention is to provide a kind of Chinese medicine composition of comparing the shorter treatment burn of prior art the course for the treatment of for the treatment of.
In order to realize the object of the invention, first the present invention provides a kind of pharmaceutical composition for the treatment of burn it is characterized in that, described pharmaceutical composition is made by following crude drug: charred Radix Sanguisorbae, Caulis Spatholobi, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, Radix Ginseng and Mel.
As preferably, described pharmaceutical composition is made by the crude drug of following weight portion:
Charred Radix Sanguisorbae 25-30 part Caulis Spatholobi 10-30 part
Rhizoma Coptidis 20-30 part Rhizoma Polygoni Cuspidati 10-30 part
Radix Ginseng 5-10 part Mel 10-30 part.
More preferred, described pharmaceutical composition is made by the crude drug of following weight portion:
20 parts of 28 portions of Caulis Spatholobis of charred Radix Sanguisorbae
10 parts of 26 parts of Rhizoma Polygoni Cuspidati of Rhizoma Coptidis
10 parts of 6 parts of Mel of Radix Ginseng.
The present invention also further provides the preparation that contains aforementioned pharmaceutical composition, and as preferably, described preparation is unguentum.
The preparation method of described unguentum comprises the steps:
1) above Six-element crude drug, except Mel, is ground into fine powder by five tastes crude drug such as all the other charred Radix Sanguisorbae, crosses 80-200 mesh sieve, with Oleum Brassicae campestris-Oleum Sesami 60-70 part, stirs evenly, and places 2 days;
2) separately get 60 parts of white vaseline 770-780 part, lanolines, 130 ℃ of heating, after 30 minutes, let cool to 100 ℃, add the medicated powder of above-mentioned Oleum Brassicae campestris-Oleum Sesami infiltration, and 100 ℃ of constant temperature stir 20 minutes, let cool to 60 ℃, add Mel, stir evenly, and make 1000g, obtain.
Wherein, in described Oleum Brassicae campestris-Oleum Sesami, the proportioning ratio of Oleum Brassicae campestris and Oleum Sesami is 15:1.
The preparation method of described Oleum Brassicae campestris-Oleum Sesami is: the machine of getting squeezes Oleum Brassicae campestris and is stirred and heated to 215～225 ℃, is incubated 5～10 minutes, lets cool; Separately get Oleum Sesami and mix homogeneously in the ratio of 1:15 with the Oleum Brassicae campestris after above-mentioned refining, under constantly stirring, be heated to 105 ℃, be incubated 30 minutes, discard floating thing, obtain.
Another object of the present invention is to provide the application of described pharmaceutical composition in the medicine of preparation treatment burn.
In pharmaceutical composition of the present invention:
Charred Radix Sanguisorbae: cooling blood for hemostasis, pathogenic fire purging sore.After Radix Sanguisorbae parch to black, can strengthen its hemostasis and sore effect.
Caulis Spatholobi: the promoting the circulation of blood of enriching blood, the meridian dredging.
Rhizoma Polygoni Cuspidati: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis is not Xiaed ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
Radix Ginseng: strongly invigorating primordial QI, Gu de-, promote the production of body fluid, calm the nerves.
Mel: skin moistening granulation promoting; Removing toxic substances.
Beneficial effect of the present invention is:
Rhizoma Polygoni Cuspidati in the present invention's prescription: expelling wind and removing dampness, dissipating blood stasis analgesic therapy, heat-clearing and toxic substances removing, for burn due to hot liquid or fire, the swollen sore of pain.Charred Radix Sanguisorbae: cooling blood for hemostasis, pathogenic fire purging sore.Caulis Spatholobi: the promoting the circulation of blood of enriching blood, the meridian dredging.Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Radix Ginseng: strongly invigorating primordial QI, Gu de-, promote the production of body fluid, to calm the nerves, in pain is contained, gaseous pulse must be anxious, therefore calm the nerves with Radix Ginseng.Mel, skin moistening granulation promoting, removing toxic substances.Oleum Sesami: lubricant and excipient, removing toxic substances and promoting granulation.For ulcer, the skin ulcer chapped skin that swells.All medicine compatibilities, play heat-clearing and toxic substances removing altogether, putrefaction-removing granulation-promoting, the merit of sore closing in and analgesic therapy.
Pharmaceutical composition of the present invention verifies through clinical trial, evident in efficacy to burn symptom, and treatment to compare prior art the course for the treatment of shorter, thereby shortened patient's the recovery time, alleviated patient's the pain of injury.
The specific embodiment
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.
Embodiment 1 drug combination preparation of the present invention (unguentum)
Prescription: charred Radix Sanguisorbae 28g, Caulis Spatholobi 20g, Rhizoma Coptidis 26g, Rhizoma Polygoni Cuspidati 10g, Radix Ginseng 6g, Mel 10g.
Method for making: above Six-element, except Mel (refining), the five tastes such as all the other charred Radix Sanguisorbae are pulverized and claimed fine powder, cross 80-200 mesh sieve, with Oleum Brassicae campestris-Oleum Sesami (15:1) (refining) 60-70g, stir evenly, and place 2 days.Separately get white vaseline 770-780g, lanoline 60g, 130 ℃ of heating, after 30 minutes, let cool to 100 ℃, add the medicated powder of above-mentioned Oleum Brassicae campestris-Oleum Sesami (15:1) (refining) infiltration, constant temperature (100 ℃) stirs 20 minutes, lets cool to 60 ℃, adds Mel (refining), stir evenly, make 1000g, obtain.
Wherein: the method for making of Oleum Brassicae campestris-Oleum Sesami (15:1) (refining): the machine of getting squeezes Oleum Brassicae campestris and is stirred and heated to 215～225 ℃, is incubated 5～10 minutes, lets cool; Separately get Oleum Sesami and mix homogeneously in the ratio of 1:15 with the Oleum Brassicae campestris after above-mentioned refining, under constantly stirring, be heated to 105 ℃, be incubated 30 minutes, discard floating thing, obtain.
Function cures mainly: heat-clearing and toxic substances removing, granulation promoting pain relieving.For shallow/dark two degrees and three degrees, burn/scald, the area of burning is less than 10%.
Usage and dosage: with normal saline, clean wound surface, ointment is evenly spread upon on antiseptic gauze, the thick about 2mm of powder, flap coverage, is optionally wrapped up or half exposure.1 time on the one.
Embodiment 2 drug combination preparation of the present invention (unguentum)
Prescription: charred Radix Sanguisorbae 25g, Caulis Spatholobi 10g, Rhizoma Coptidis 20g, Rhizoma Polygoni Cuspidati 30g, Radix Ginseng 10g, Mel 15g.
All the other are with embodiment 1.
Embodiment 3 drug combination preparation of the present invention (unguentum)
Prescription: charred Radix Sanguisorbae 30g, Caulis Spatholobi 30g, Rhizoma Coptidis 30g, Rhizoma Polygoni Cuspidati 15g, Radix Ginseng 5g, Mel 30g.
All the other are with embodiment 1.
The clinical trial of experimental example 1 pharmaceutical composition of the present invention
1. clinical data
Clinical observation 161 examples (wherein experimental group 86 examples, matched group 75 examples).Patient is divided into two groups at random, respectively external application ointment of the present invention and ZIHUA SHAOSHANGGAO.
2. Therapeutic Method
2.1 embodiment of the present invention 1 unguentum are applied to affected part equably, change dressings every day once, within 7 days, are a course for the treatment of.
2.2 ZIHUA SHAOSHANGGAO (Shandong Mei Bao pharmaceutcal corporation, Ltd produces, the accurate word Z10930029 of traditional Chinese medicines), external application affected part, determines by affected part size, changes once every day, within 7 days, be a course for the treatment of.
3. criterion of therapeutical effect
Criterion of cure: subcutaneous swelling is obviously being disappeared, private prosecution pain and heating obviously alleviate, and initial stage medication is without the Tension Vesicle person of appearance.
According to above-mentioned standard, by the time evaluation curative effect that continues medication.Learn and process by statistics, two groups of curative effects have significant difference (P <0.01), and experimental group curative effect is better than matched group, and efficacy result is in Table 1.
Table 1 liang is formed the average healing days comparison of face (note: P<0.05)
| Group | Number of cases | Shallow two degree | Dark two degree | Three degree |
| Of the present invention group | 86 | 8±3.5 | 12±4.5 | 21±5.5 |
| ZIHUA SHAOSHANGGAO group | 75 | 11±4.0 | 18±3.5 | 35±6.5 |
Through verification experimental verification, the embodiment of the present invention 2 all has therapeutic effect similarly to Example 1 with embodiment 3.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements, all belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (8)
1. a pharmaceutical composition for the treatment of burn, is characterized in that, described pharmaceutical composition is made by following crude drug: charred Radix Sanguisorbae, Caulis Spatholobi, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, Radix Ginseng and Mel.
2. pharmaceutical composition according to claim 1, is characterized in that, described pharmaceutical composition is made by the crude drug of following weight portion:
Charred Radix Sanguisorbae 25-30 part Caulis Spatholobi 10-30 part
Rhizoma Coptidis 20-30 part Rhizoma Polygoni Cuspidati 10-30 part
Radix Ginseng 5-10 part Mel 10-30 part.
3. pharmaceutical composition according to claim 2, is characterized in that, described pharmaceutical composition is made by the crude drug of following weight portion:
20 parts of 28 portions of Caulis Spatholobis of charred Radix Sanguisorbae
10 parts of 26 parts of Rhizoma Polygoni Cuspidati of Rhizoma Coptidis
10 parts of 6 parts of Mel of Radix Ginseng.
4. the preparation that contains the pharmaceutical composition described in claim 1-3 any one, is characterized in that, described preparation is unguentum.
5. the preparation method of preparation described in claim 4, is characterized in that, comprises the steps:
1) above Six-element crude drug, except Mel, is ground into fine powder by five tastes crude drug such as all the other charred Radix Sanguisorbae, crosses 80-200 mesh sieve, with Oleum Brassicae campestris-Oleum Sesami 60-70 part, stirs evenly, and places 2 days;
2) separately get 60 parts of white vaseline 770-780 part, lanolines, 130 ℃ of heating, after 30 minutes, let cool to 100 ℃, add the medicated powder of above-mentioned Oleum Brassicae campestris-Oleum Sesami infiltration, and 100 ℃ of constant temperature stir 20 minutes, let cool to 60 ℃, add Mel, stir evenly, and make 1000g, obtain.
6. preparation method according to claim 5, is characterized in that, in described Oleum Brassicae campestris-Oleum Sesami, the proportioning ratio of Oleum Brassicae campestris and Oleum Sesami is 15:1.
7. preparation method according to claim 6, is characterized in that, the preparation method of described Oleum Brassicae campestris-Oleum Sesami is: the machine of getting squeezes Oleum Brassicae campestris and is stirred and heated to 215～225 ℃, is incubated 5～10 minutes, lets cool; Separately get Oleum Sesami and mix homogeneously in the ratio of 1:15 with the Oleum Brassicae campestris after above-mentioned refining, under constantly stirring, be heated to 105 ℃, be incubated 30 minutes, discard floating thing, obtain.
8. the application of the pharmaceutical composition described in claim 1-3 any one in the medicine of preparation treatment burn.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310752028.6A CN103751333B (en) | 2013-12-31 | 2013-12-31 | Medicinal composition for treating burns and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310752028.6A CN103751333B (en) | 2013-12-31 | 2013-12-31 | Medicinal composition for treating burns and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103751333A true CN103751333A (en) | 2014-04-30 |
| CN103751333B CN103751333B (en) | 2015-07-01 |
Family
ID=50518760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310752028.6A Active CN103751333B (en) | 2013-12-31 | 2013-12-31 | Medicinal composition for treating burns and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103751333B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481826A (en) * | 2002-09-11 | 2004-03-17 | 李宗珊 | Ointment for scald and ulcer and its preparation method |
| CN102416090A (en) * | 2011-12-19 | 2012-04-18 | 大连创达技术交易市场有限公司 | External ointment for treating burn |
| CN102861150A (en) * | 2012-09-25 | 2013-01-09 | 李书明 | Chinese medicine powder for treating burn and scald and anabrosis |
-
2013
- 2013-12-31 CN CN201310752028.6A patent/CN103751333B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481826A (en) * | 2002-09-11 | 2004-03-17 | 李宗珊 | Ointment for scald and ulcer and its preparation method |
| CN102416090A (en) * | 2011-12-19 | 2012-04-18 | 大连创达技术交易市场有限公司 | External ointment for treating burn |
| CN102861150A (en) * | 2012-09-25 | 2013-01-09 | 李书明 | Chinese medicine powder for treating burn and scald and anabrosis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103751333B (en) | 2015-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103055052A (en) | Cream for treating burn and scald and preparation method of cream | |
| CN102335309A (en) | Formula of ointment for treating burns and scalds | |
| WO2012100754A1 (en) | Chinese medicine composition for treating stab wounds, burns, and various traumas | |
| CN102119975B (en) | Chinese herbal medicine ointment for treating ulcer, bedsore and vascular dermatoses | |
| CN103845578A (en) | External tincture for treating burns, bedsore and herpes zoster and preparation method thereof | |
| CN104027483B (en) | Traditional Chinese medicine ointment for treating burn and scald and preparation method thereof | |
| CN101066307B (en) | Scar-free burn treating medicine powder and its preparation | |
| CN1076622A (en) | Blood-activating analgetic plaster for tumour | |
| CN103446240B (en) | Traditional Chinese medicine composition for rapidly healing wounds | |
| CN101983652A (en) | Traditional Chinese medicine for treating scapulohumeral periarthritis | |
| CN103751333B (en) | Medicinal composition for treating burns and preparation method thereof | |
| CN111821373B (en) | Traditional Chinese medicine hydrogel external application patch for treating phlebitis | |
| CN103908600A (en) | Externally-applied medicine for treating rheumatoid arthritis damp-heat blockage symptom as well as preparation method and administration method thereof | |
| CN102671046A (en) | Chinese medicament for treating chronic appendicitis | |
| CN103028044B (en) | Paste for treating burns and scalds | |
| CN105663157A (en) | Drug for treating burning and scalding and preparation method thereof | |
| CN104352599A (en) | Traditional Chinese medicine composition for treating burns and scalds | |
| CN104398606A (en) | Traditional Chinese medicine composition for treating burn and scald and preparation method for traditional Chinese medicine composition | |
| CN104491629A (en) | External traditional Chinese medicinal composition for treating perianal eczema, and preparation method thereof | |
| CN103933481A (en) | External medicine for treating cancer pain and preparation method thereof | |
| CN105343423B (en) | A kind of drug and preparation method thereof for treating eczema | |
| CN104096181B (en) | A kind of skin ulcer cream | |
| CN104491462B (en) | A kind of pharmaceutical composition for the treatment of scald | |
| CN103182042A (en) | Plaster for treating mumps, and preparation method thereof | |
| CN110420305B (en) | Traditional Chinese medicine composition for treating chronic muscle injuries and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |