CN103750052A - Sow feed additive for promoting growth and health of weaning pigs - Google Patents

Sow feed additive for promoting growth and health of weaning pigs Download PDF

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CN103750052A
CN103750052A CN201410030915.7A CN201410030915A CN103750052A CN 103750052 A CN103750052 A CN 103750052A CN 201410030915 A CN201410030915 A CN 201410030915A CN 103750052 A CN103750052 A CN 103750052A
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sow
feed additive
piglet
animal feed
lactation
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张敏红
冯京海
浦华
李素霞
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Institute of Animal Science of CAAS
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Abstract

The invention discloses a sow feed additive for promoting growth and health of weaning pigs. The feed additive disclosed by the invention is prepared by mixing all substances in parts by weight: 2 parts of enterococcus faecium, 2-3 parts of lysozyme and 95-96 parts of a carrier, wherein the carrier is starch; the viable count in the enterococcus faecium is 1.0*10<11>cfu/g; the enzyme activity of the lysozyme is 5,000,000IU/g. According to the sow feed additive, probiotics and the lysozyme serving as a natural immune component of an organism are combined so as to cooperatively promote multiplication of beneficial bacteria in the intestinal tracts of sows, reduce the amount of harmful bacteria such as escherichia coli, maintain and regulate the balance of intestinal flora of the sows, increase the number of beneficial bacteria in intestinal contents and excrements, alleviate the action caused by the harmful bacteria, purify the environments in vivo and in vitro, create a good flora environment for new-born piglets and achieve the effects of increasing the weaning weights of the piglets, increasing the weights of the pigs weaned for 3 weeks and reducing the diarrhea occurrence rate. Furthermore, the formula of the feed additive does not contain medicaments, so that drug resistance and drug residues can be avoided.

Description

A kind of weanling pig growth and healthy sow feed additive of promoting
Technical field
The invention belongs to field of animal feed, relate to a kind of weanling pig growth and healthy sow feed additive of promoting.
Background technology
Early weaning piglet is the advanced technology generally adopting in domestic and international Swine Production, can improve breeding potential, the minimizing transmission to piglet by parent of sow, and can improve the pig growth performance in growth period.But early-weaned piglets be subject to psychology, environment and nutrition stress impact, usually occur " early weaning piglet syndrome ", show as that appetite is poor, the disorders of digestion, diarrhoea, growthing lag, efficiency of feed utilization are low etc.Current, alleviate or overcome early weaning piglet irritability syndrome often by feeding and management measure and the sucking pig material of feeding.But sow disease is more and more in recent years, and is difficult to prevention and control, sow health has become the bottleneck factor of restriction pig industry development.Can therefore, whether sow health affects health and production performance after weaned piglet of future generation, by adding active component in sow feed, when improving sow health, improve weanling pig premunition and growth potential, has become industry and has started concerned issue.
Summary of the invention
The object of this invention is to provide a kind of weanling pig growth and healthy sow feed additive of promoting.
The invention provides a kind of animal feed additive, specifically each material by following parts by weight mixes: 2 parts of VREFs, lysozyme 2-3 part, carrier 95-96 part.
Wherein, described carrier specifically can be starch.
In described animal feed additive, the viable count in described VREF is specially 1.0 * 10 11cfu/g; The enzyme activity of described lysozyme is specially 5,000,000 IU/g.
In the present invention, described VREF is specially intercrescence biotech inc, Taiwan product, and catalogue name is called Enterococcus Faecium(1Kg/pack).Described lysozyme is specially Investment Co., Ltd of Australian Yi Tai group (China) product, and catalogue name is called every gram of 500Wan unit of easy safe lysozyme 500().
The animal feed that contains described animal feed additive also belongs to protection scope of the present invention.
A further object of the present invention is to provide the preparation method of described animal feed additive.
The preparation method of described animal feed additive provided by the present invention, specifically can comprise the steps:
(1) take the described VREF of 2 weight portions, mix with the described carrier (as starch) of 10-15 times of weight, make VREF pre-mixing agent;
(2) take the described lysozyme of 2-3 weight portion, mix with the described carrier of 10-15 times of weight, make lysozyme premix;
(3) by the lysozyme premix of the VREF pre-mixing agent of step (1) gained, step (2) gained, and remaining described carrier mixing, described animal feed additive made;
Described carrier in described carrier in step (1), step (2) and the weight summation of the remaining described carrier described in step (3) are 95-96 weight portion.
Described animal feed additive, or the application of described animal feed at following (I) or (II) also belongs to protection scope of the present invention:
(I) preparation promotes weanling pig growth and/or healthy product;
(II) preparation reduces the product of sows in lactation weightlessness.
Another object of the present invention is to provide a kind of method that promotes weanling pig growth and/or health, or a kind of method that reduces sows in lactation weightlessness.
Promotion weanling pig provided by the present invention growth and/or healthy method, or the method for reduction sows in lactation weightlessness, specifically in 90-95 days (as the 93rd day) of sow gestation, start, in sow diets, add after described animal feed additive, sow is fed, until lactation finishes.
In described method, the addition of described animal feed additive specifically can be: add animal feed additive as described in 500-600 gram (as 500 grams) in described sow diets per ton (powder).
Further, described sow diets is: the sow heavy in pig daily ration (using in latter half of gestation) that constituent is as shown in table 1, or constituent sow in lactation daily ration (using lactation) as shown in table 1.
In above-mentioned application or method, the piglet of described weanling pig for weaning when 21 age in days.
In above-mentioned application or method, the growth of described promotion weanling pig, specifically may be embodied in as lower at least one:
(a1) described in while weaning, the body weight of piglet is higher than contrast piglet of the same age;
(a2) body weight of wean described piglet after three weeks is higher than contrast piglet of the same age;
(a3) when wean, after weaning three weeks, stop, the daily gain of described piglet is higher than contrast piglet of the same age.
In above-mentioned application or method, described promotion weanling pig is healthy, specifically may be embodied in as lower at least one:
(b1) when weaning only, the survival rate of described piglet is higher than contrast piglet of the same age;
(b2) lactation, the diarrhea rate of described piglet is lower than contrast piglet of the same age;
(b3), when birth, during to 6 week age, only, the diarrhea rate of described piglet is lower than contrast piglet of the same age.
At above (a1)-(a3), and (b1)-(b3) in, described contrast piglet of the same age all meets following condition: in stopping during this period of time to lactation when 90-95 days of mother's gestation from described contrast piglet of the same age, in sow diets, do not add described animal feed additive when sow is fed.In addition, described contrast mother of piglet of the same age and mother of described piglet raise under same condition; Described contrast piglet of the same age and described piglet are also raised under same condition.
In above-mentioned application or method, described sows in lactation is weightless deducts the body weight of described sow when finish lactation for the initial body weight of sow in lactation.Described reduction sows in lactation is weightless, specifically may be embodied in: described sow lactation weightlessness lower than concurrent control sow.Described concurrent control sow is: when from 90-95 days of gestation to lactation only during this period of time in, in sow diets, do not add the sow that described animal feed additive is fed.In addition, described concurrent control sow and described sow are raised under same condition.
In the present invention, above all described animals all can be pig.
In the present invention, above all pigs all can be the binary pig that grows up.
The present invention combines probio and body innate immunity composition lysozyme, both are collaborative promotes sow intestinal beneficial bacterium propagation, reduction harmful intestinal tract bacteria as Escherichia coli quantity, safeguard and regulate sow gut flora balance, impel and increase intestinal contents and excreta beneficial bacterium quantity, reduce the effect of harmful bacteria quantity, purification body internal and external environment, creates better flora environment to its newborn piglet.Play improve weaned piglet heavy, improve 3 weeks daily gains after weaned piglet and reduce the effect of Incidence of Diarrhea.And feed addictive prescription provided by the present invention, containing medicine, can not develop immunity to drugs and medicament residue.
The specific embodiment
The experimental technique using in following embodiment if no special instructions, is conventional method.
In following embodiment, material used, reagent etc., if no special instructions, all can obtain from commercial channels.
Described VREF is intercrescence biotech inc, Taiwan product, and catalogue name is called Enterococcus Faecium(1Kg/pack).
Described lysozyme is specially Investment Co., Ltd of Australian Yi Tai group (China) product, and catalogue name is called every gram of 500Wan unit of easy safe lysozyme 500().
The preparation of embodiment 1, sow feed additive
1, (living bacteria count is 1.0 * 10 to take the VREF (Enterococcus Faecium) of 2 weight portions 11cfu/g), the starch of the lysozyme of 3 weight portions (enzyme activity is 5,000,000 IU/g) and 95 weight portions.
The starch of 95 weight portions that 2, take from step 1, take out 20 weight portions, (living bacteria count is 1.0 * 10 to the VREF of 2 weight portions that step 1 is taken (Enterococcus Faecium) 11cfu/g) mix wherein extremely evenly, make VREF pre-mixing agent.
The starch of 95 weight portions that 3, take from step 1, take out 30 weight portions, the lysozyme of 3 weight portions that step 1 is taken mixes wherein extremely evenly, makes lysozyme premix again.
4, VREF pre-mixing agent step 2 being made, the lysozyme premix that step 3 makes, and in step 1, the starch of remaining 45 weight portions mixes, and makes sow feed additive.
Embodiment 2, sow feed additive are on weanling pig growth and healthy impact
One, experimental animal and grouping
Select grow up 22 of sows of the binary of health, the good 3-5 parity of body condition, delivery time close (being separated by 5 days in), by blood relationship, gestation date, principle that body weight is close, be divided at random 2 processing (control group, interpolation group), each processes 11 sows.Raise on every single hurdle of sow, interpolation group and 2 hurdles, control group interval.
The test sow cub of institute pig is carried out 21 age in days wean, and also the experimental design with reference to sow is divided into two processed group.Wean turns and continues after group by the nest subfield feed identical with lactation of feeding.
With reference to the nutrition requirements of NRC (1998) pig, make respectively sow heavy in pig daily ration, sow in lactation daily ration and newborn piglet diet (in Table 1), test daily ration is powder.
From the 93rd day of sow gestation, in the sow heavy in pig daily ration of interpolation group per ton and sow in lactation daily ration, add the sow feed additive of 500 grams of embodiment, 1 preparation.
Table 1 basal diet forms and trophic level (basis of feeding)
Figure BDA0000460279860000041
Figure BDA0000460279860000051
Note: 1: premix provides VA8000IU for every kilogram of sow heavy in pig daily ration and sow in lactation daily ration; VD 31300IU; VE30IU; VK 31.5mg; VB 11.0mg; VB 23.2mg; VB 61.5mg; VB 120.02mg; Folic acid 1.28mg; Biotin 0.168mg; Nicotinic acid 16mg; Pantothenic acid 10mg; Cu11.5mg; Fe140mg; Zn65mg; Mn37.5mg; Se0.35mg; I0.5mg.Premix provides VA4800IU for every kilogram of newborn piglet diet; VD3880IU; VE30IU; VK32.4mg; VB12.0mg; VB28mg; VB61.2mg; VB120.03mg; Folic acid 2.0mg; Biotin 0.2mg; Nicotinic acid 40mg; Pantothenic acid 25mg; Cu14.4mg; Fe120mg; Zn125mg; Mn50mg; Co0.48mg; Se0.3mg; I0.3mg.
Two, test pig feeding and management
The every management of duration of test is carried out routinely, and in latter half of gestation (93d is to childbirth), sow is raised at 2.0~2.5kg according to body condition limit every day, in lactation, 3d controlled feeding before sow, feeds with 2.0kg, 2.5kg, 3.0kg respectively, the 4th day starts free choice feeding, freely drinks water.Breast piglet starts to search for food on the 5th day, nipple-shaped drinker, free choice feeding and drinking-water.21 age in days wean, continue after wean to observe 3 weeks.
Three, observation index
Test piglet is nascent, when wean (21 age in days), off-test (42 age in days), weigh on an empty stomach; The repetition (nest, hurdle) of take is unit, records feed consumption rate; Calculate each stage and omnidistance piglet daily gain, feed intake, material anharmonic ratio.The repetition (nest, hurdle) of take is unit, records day by day diarrhoea situation and death condition, statistics diarrhea frequency and the death rate.
Diarrhea frequency (%)=pig's head number of days/overall test pig's head number of days * 100% of always suffering from diarrhoea;
The death rate (%)=total death toll/total number * 100%.
(in " diarrhea frequency " computing formula, as 3 days diarrhoea of 1 pig, being 3 pig's head number of days)
Four, the impact of sow feed additive on sow reproductive performance
The feed addictive of additional embodiment 1 preparation in sow heavy in pig daily ration and sow in lactation daily ration, result shows, feed addictive to the litter size of sow, produce the young number of living, the young rate of living, nascent nose heave and nascent litter weight have no significant effect (P>0.05).Compare with control group, the weight of weaning litter of interpolation group, wean individual weight and number of weaned all significantly improve (P<0.05), sows in lactation is weightless significantly to decline (P<0.05), but the not impact (P>0.05) of feed consumption rate lactation; Sow is weaned to inter oestrual period shortening trend, but there is no significant difference.Refer to table 2.
The impact of table 2 feed addictive on sow reproductive performance
? Interpolation group Control group
Litter size (head) 11.2±2.67 10.26±1.63
Produce the young number (head) of living 10.75±2.21 9.61±1.71
Nascent litter weight (Kg) 15.67±1.88 13.68±0.89
Nascent individual weight (Kg) 1.47±0.15 1.41±0.69
Weight of weaning litter (Kg) 70.81±6.01 a 59.31±3.43 b
Wean individual weight (Kg) 6.59±0.27 a 6.17±0.10 b
Number of weaned (%) 94.12±0.73 a 90.55±1.41 b
Farrowing day heavy (Kg) 233.17±11.24 232.38±12.09
Sow wean day heavy (Kg) 223.52±12.16 219.31±12.35
Sows in lactation weightless (Kg) 9.65±2.15 b 13.07±2.19 a
The total feed consumption rate of sows in lactation (Kg) 151.95±5.03 149.79±4.93
Sow is weaned to inter oestrual period (day) 6.17±1.12 6.98±0.97
Note: colleague's data shoulder mark different letter representation significant differences (P<0.05).
Five, the impact of additive on piglet growth and diarrhea frequency
In sow heavy in pig daily ration and sow in lactation daily ration, the feed addictive of additional embodiment 1 preparation, can significantly affect its offspring's weaned piglets, the results are shown in table 3.Additive can significantly improve the body weight (P<0.05) of 21 age in days weanling pigs, but also the piglet growth of 3 weeks after impact wean, significantly improve the wean daily gain (P<0.05) of latter 3 weeks, reduce material anharmonic ratio (P<0.05).
The impact of table 3 additive on weaned piglets
Figure BDA0000460279860000061
Note: colleague's data shoulder mark different letter representation significant differences (P<0.05).
The feed addictive of embodiment 1 preparation the results are shown in Table 4 to the impact of grice diarrhoea frequency.In lactation, interpolation group grice diarrhoea frequency ratio control group reduces by 32.87%; After wean in 3 weeks, the 4th week grice diarrhoea of control group rises larger, and interpolation group also rises to some extent, but that control group is organized than interpolation is high by 45.70%, and the 4-6 week control group grice diarrhoea rate after wean is higher than interpolation group 45.15%; Test full phase statistics, interpolation group is compared with control group, and diarrhea rate reduces by 40.07%.Test shows that the feed addictive of additional embodiment 1 preparation in sow diets has the effect of alleviating grice diarrhoea.
Impact (the diarrhea frequency unit: %) of table 4 additive on grice diarrhoea
? Interpolation group Control group
1W 3.03 2.65
2W 5.25 7.93
3W 6.05 10.78
Lactation (0-3W) 4.78 7.12
4W 7.32 13.48
5W 6.27 10.13
6W 3.21 7.01
4-6w 5.60 10.21
The full phase (0-6W) 5.19 8.66

Claims (10)

1. animal feed additive, is mixed by each materials of following parts by weight: 2 parts of VREFs, lysozyme 2-3 part, carrier 95-96 part.
2. animal feed additive according to claim 1, is characterized in that: described carrier is starch.
3. animal feed additive according to claim 1 and 2, is characterized in that: the viable count in described VREF is 1.0 * 10 11cfu/g; The enzyme activity of described lysozyme is 5,000,000 IU/g.
4. the animal feed that contains arbitrary described animal feed additive in claim 1-3.
5. the preparation method of arbitrary described animal feed additive in claim 1-3, comprises the steps:
(1) take the claim 1-3 of the 2 weight portions VREF described in arbitrary, mix with the carrier described in the claim 1-4 of 10-15 times of weight is arbitrary, make VREF pre-mixing agent;
(2) take the claim 1-3 of the 2-3 weight portion lysozyme described in arbitrary, mix with the described carrier of 10-15 times of weight, make lysozyme premix;
(3) by the lysozyme premix of the VREF pre-mixing agent of step (1) gained, step (2) gained, and remaining described carrier mixing, described animal feed additive made;
Described carrier in described carrier in step (1), step (2) and the weight summation of the remaining described carrier described in step (3) are 95-96 weight portion.
6. the application of arbitrary described animal feed additive in claim 1-3, or animal feed claimed in claim 4 at following (I) or (II):
(I) preparation promotes weanling pig growth and/or healthy product;
(II) preparation reduces the product of sows in lactation weightlessness.
7. promoting weanling pig growth and/or a healthy method, is the starting for 90-95 days of sow gestation, adds in claim 1-3 after arbitrary described animal feed additive in sow diets, sow is fed, until lactation finishes.
8. reducing a method for sows in lactation weightlessness, is the starting for 90-95 days of sow gestation, adds in claim 1-3 after arbitrary described animal feed additive in sow diets, sow is fed, until lactation finishes.
9. according to the method described in claim 7 or 8, it is characterized in that: the addition of described animal feed additive is: in described sow diets per ton, add 500-600 gram of described animal feed additive.
10. according to arbitrary described application or method in claim 6-9, it is characterized in that: the piglet of described weanling pig for weaning when 21 age in days; Or
The growth of described promotion weanling pig, is embodied in as lower at least one:
(a1) described in while weaning, the body weight of piglet is higher than contrast piglet of the same age;
(a2) body weight of wean described piglet after three weeks is higher than contrast piglet of the same age;
(a3) when wean, after weaning three weeks, stop, the daily gain of described piglet is higher than contrast piglet of the same age;
Or
Described promotion weanling pig is healthy, is embodied in as lower at least one:
(b1) when weaning only, the survival rate of described piglet is higher than contrast piglet of the same age;
(b2) lactation, the diarrhea rate of described piglet is lower than contrast piglet of the same age;
(b3), when birth, during to 6 week age, only, the diarrhea rate of described piglet is lower than contrast piglet of the same age;
(a1)-(a3), and (b1)-contrast piglet of the same age described in (b3) all meets following condition: when 90-95 days of mother's gestation from described contrast piglet of the same age to lactation only during this period of time in, when sow is fed, in sow diets, do not add described animal feed additive;
Or
Described sows in lactation is weightless deducts the body weight of described sow when finish lactation for the initial body weight of sow in lactation.Described reduction sows in lactation is weightless, is embodied in: described sow lactation weightlessness lower than concurrent control sow; Described concurrent control sow is: when from 90-95 days of gestation to lactation only during this period of time in, in sow diets, do not add the sow that described animal feed additive is fed.
CN201410030915.7A 2014-01-22 2014-01-22 Sow feed additive for promoting growth and health of weaning pigs Pending CN103750052A (en)

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US12133542B2 (en) 2018-04-25 2024-11-05 Novozymes A/S Animal feed compositions and uses thereof

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Publication number Priority date Publication date Assignee Title
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US12133542B2 (en) 2018-04-25 2024-11-05 Novozymes A/S Animal feed compositions and uses thereof
WO2022194728A1 (en) * 2021-03-16 2022-09-22 Dsm Ip Assets B.V. Animal feed composition and use thereof

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Application publication date: 20140430