Utilize pointolite every bottle detection instrument
Technical field
This technological invention is a kind of modernization Fast Detection Technique of the product quick tests such as biology, medicine, chemical industry, food.
Background technology
The bottled samples such as current many invaluable liquid drugs, biological products, vaccine and chemical industry become the object that lawless person fakes, and mostly must use uncork inspection for conventional sense or the fast monitored of these bottling liquid samples; Uncork inspection exists following shortcoming: the one, need special instrument and equipment and reagent reagent, and to waste time and energy, inspection cost is high; The 2nd, as just not re-using after these resource scarcitys such as human serum albumin, vaccine and valuable sample uncork, sample resource is caused to greatly waste; The 3rd, some is not only expensive as antineoplastic, and uncork inspection exists cellular toxicity pollution to personnel and environment; The 4th, due to the samples such as many blood products, biological products and cancer therapy drug be subject to test condition and inspection qualification restriction, the whole nation except the condition and qualification of indivedual medicine inspecting institute, inspection that quality inspection possesses, most of medicine inspecting institute, quality inspection all can not implement check; In addition, current existing detecting instrument, due to the restriction of light source, apparatus structure, can not be eliminated reflective, the scattering of sample bottle and disturb, and detect the single feature of index, can only detect the single index of sample in bottle, and can not implement to survey every the many indexs of bottle; Due to above-mentioned many reasons, cause many fake and forged samples not investigate and prosecute in time, to the people's greatly danger that causes safe and effective for medication; So, study a kind of equipment every the bottle quick detection sample true and false and be determined to win.
Summary of the invention
Technical matters to be solved by this invention is to overcome the deficiencies in the prior art, and a kind of directly character of material or the device of content in bottle is surveyed bottle are provided.Bottle wall and the interference of solution to incident light are eliminated with pointolite by this invention technology system; With fastening in gathering and regulate sample bottle relative position to make outgoing light can drop on effective Photoelectric Detection scope; Utilize pointolite, eliminated the interference of bottle wall to incident light; Utilize optical, electrical detection system to rotate together with sample bottle, make carrier fluid bottle position and empty bottle position in testing process keep relative consistent with launching spot position, eliminated the interference of empty bottle part; Utilize and polariscopy device and photoelectric displacement determinator are installed in light path are detected the optical indexes such as the absorbance, optical activity, refractive index of carrier fluid position and empty bottle position simultaneously, by the poor formula calculation process of system, the in the situation that of not uncork, directly obtain above-mentioned every optical index of sample in bottle outlet, to find out the quality condition of bottle content.This technological invention has realized directly and has detected with operation full-automatic every bottle, without reagent reagent, the method economy, environmental protection, simple and quick, be particularly suitable for the online of bottled product and the fast monitored/detection to costly medicine, biological products, vaccine, testing reagent.
technical solution of the present invention is as follows:
Utilize pointolite every bottle detection instrument, comprise system fixed support (101), sample bottle sky, carry position conversion device (102), point light source system (103), polarized light determinator (104), sample bottle light path position regulator (105), emergent light intensity, displacement detecting apparatus (106), control system (107) seven parts;
Sample bottle sky, carry position conversion device (102) and be arranged in the top of system fixed support (101), sample bottle sky, the left rotation and right rotation of carrying position conversion device (102) supports tubular shaft (202) and is embedded in the hole, left and right of system fixed support (101), and matches in rotation striking gear (205), pointolite conversion portion (303), polarized light determinator (104), sample bottle light path position regulator (105) and emergent light intensity, displacement detecting apparatus (106) is all positioned at rotatable cabin (201), from left to right pointolite conversion portion (303), preposition polariscope (401), sample bottle light path position regulator (105), rearmounted polariscope (403) and emergent light intensity, displacement detecting apparatus (106) is according to the order of sequence word order and is fixed on the base plate of rotatable cabin (201), conduction optical fiber (302) and emergent light intensity, displacement detecting apparatus (106) circuit through left rotation and right rotation support tubular shaft (202) hole respectively with the monochromatic light conversion portion (301) of system fixed support (101) bottom, control system (107) is connected.
Described sample bottle sky, year position conversion device (102) are mainly made up of rotatable cabin (201), left rotation and right rotation support tubular shaft (202), sample bottle hatchcover (203), sample bottle light path position view window (204); Sample bottle hatchcover (203) is positioned at rotatable cabin (201) top with sample bottle light path position view window (204), left rotation and right rotation supports tubular shaft (202) and is connected to the left and right sides, the thumb wheel phase interlock of the gear on tubular shaft and system fixed support (101) striking gear (205), rotatable cabin (201) is inner to be supported tubular shaft (202) hole through left rotation and right rotation and communicates with system fixed support (101).
Described point light source system (103) point monochromatic light conversion portion (301), conduction optical fiber (302), pointolite conversion portion (303), monochromatic light conversion portion (301) is positioned at the bottom left end of system fixed support (101), pointolite conversion portion (303) is positioned at rotatable cabin (201), conduction optical fiber (302) supports tubular shaft (202) hole through left rotation and right rotation and is connected with the two, point light source system (103) is mainly by luminophor, diffraction grating, lens, optical filter, collimating apparatus, optical fiber, light hurdle composition, wherein said luminophor can be the long Long service lamp of all-wave or semiconductor laser or LED cold light source, use wavelength is adjustable.
Described polarized light determinator (104) is mainly made up of preposition polariscope (401), electronic capstan (402), rearmounted polariscope (403), preposition polariscope (401) is embedded in electronic capstan (402) center pit, and electronic capstan (402) and rearmounted polariscope (403) are separately fixed at the both sides of rotatable cabin (201) bottom sample bottle light path position regulator (105); Electronic capstan (402) can exchange with the position of rearmounted polariscope (403).
Described sample bottle light path position regulator (105) is mainly made up of left and right fixed support (501), bottle clip plate degree of tilt adjusting bracket (502), left and right bottle clip plate (503), the bottle clip plate screw rod (504) that moves to right; Bottle clip plate degree of tilt adjusting bracket (502) is positioned at left and right fixed support (501) inner side, left and right bottle clip plate (503) bottom is positioned in the middle of bottle clip plate degree of tilt adjusting bracket (502) biside plate, its left and right bottle clip plate (503) is provided with upper and lower axis hole and screw straggly, and move to right screw rod (504) and bottle clip plate of bottle clip plate moves to left screw rod (505) is applied in by axis hole left and right fixed support (501), bottle clip plate degree of tilt adjusting bracket (502), left and right bottle clip plate (503) respectively with screw together with.
Described emergent light intensity, displacement detecting apparatus (106) are positioned at rotatable cabin (201), are mainly made up of photelectric receiver (601), linear motion system (602); Photelectric receiver (601) is fixed on linear motion system (602), and can be shifted with linear motion system (602), photelectric receiver (601) and linear motion system (602) also can adopt PSD displacement detector to replace, and its transmission line supports tubular shaft (202) center pit through left rotation and right rotation and passes with control system (107) and be connected; Photelectric receiver (601) can be photoelectric cell, photoelectric tube, PSD displacement detector, line array CCD or area array CCD.
Described control system (107) is positioned at the bottom of system fixed support (101), is mainly made up of kinetic control system, electrical apparatus control system, temperature control system, Photoelectric Detection disposal system, touch-screen, supply unit.
the present invention, with respect to prior art, has the following advantages:
1), having realized that bottled sample liquid directly enters every bottle is qualitative or quantitative automatic monitoring/detection;
2), this technology is without uncork, do not destroy sample, directly finds out content character and quality every bottle, i.e. energy-conservation environmental protection again;
3), survey without other instrument and equipments and reagent reagent, cost is low, speed is fast, efficiency is high;
4), the sample of detection is not subject to the impact of external environment, the sample detecting still can continue to use;
5), automaticity is high, simple to operate;
6) can realize the detection of the multinomial optical indexes such as multi-wavelength absorbance log, optical activity, refractive index, simultaneously, survey the wide application of sample.
brief description of the drawings
Fig. 1 utilizes pointolite every bottle detection instrument schematic diagram
Fig. 2 is sample bottle sky, year position conversion device schematic diagram
Fig. 3 is point light source system schematic diagram
Fig. 4 is polarized light determinator schematic diagram
Fig. 5 is sample bottle light path position regulator schematic diagram
Fig. 6 is emergent light intensity, displacement detecting apparatus schematic diagram
concrete embodiment
This technological invention is described below according to drawings and embodiments
As shown in Figure 1, utilize pointolite mainly to be formed by system fixed support 101, sample bottle sky, year position conversion device 102, point light source system 103, polarized light determinator 104, sample bottle light path position regulator 105, emergent light intensity, displacement detecting apparatus 106, control system 107 7 parts every bottle detection instrument structure;
As shown in Figure 2, sample bottle sky, year position conversion device 102 are arranged in the top of system fixed support 101, are mainly made up of rotatable cabin 201, left rotation and right rotation support hollow wheel 202, sample bottle hatchcover 203, sample bottle light path position detection window 204; Rotatable cabin 201 upper ends are provided with sample bottle hatchcover 203 and sample bottle light path position view window 204, two ends are connected with left rotation and right rotation and support tubular shaft 202, and be connected mutually with system fixed support 101 thumb wheels, pointolite conversion portion 303, polarized light determinator 104, sample bottle light path position regulator 105, emergent light intensity, displacement detecting apparatus 106 have been installed in rotatable cabin 201 bottoms;
In the time rotating rotation striking gear 205 thumb wheel, rotatable cabin 201 drives the and then rotation simultaneously of pointolite conversion portion 303, polarized light determinator 104, sample bottle light path position regulator 105 and emergent light intensity in cabin, displacement detecting apparatus 106, and the position that while making carrier fluid position and empty bottle position, incident light enters sample bottle remains unchanged;
As shown in Figure 3, 103 points of monochromatic light conversion portions 301 of point light source system, conduction optical fiber 302, pointolite conversion portion 303, monochromatic light conversion portion 301 is positioned at the bottom left end of system fixed support 101, pointolite conversion portion 303 is positioned at rotatable cabin 201, conduction optical fiber 302 supports tubular shaft 202 holes through left rotation and right rotation and is connected with the two, point light source system 103 is mainly by luminophor, diffraction grating, lens, optical filter, collimating apparatus, optical fiber, light hurdle composition, wherein said luminophor can be the long Long service lamp of all-wave or single wavelength Long service lamp or semiconductor laser or LED cold light source, use wavelength is adjustable, as while using semiconductor laser or LED light source, can save monochromatic light conversion portion 301 and conduction optical fiber 302.
As shown in Figure 4, polarized light determinator 104 is between the interior pointolite conversion portion 303 of rotatable cabin 201 and emergent light intensity, displacement detecting apparatus 106, mainly formed by preposition polariscope 401, electronic capstan 402, rearmounted polariscope 403, preposition polariscope 401 is connected on electronic capstan 402, between pointolite conversion portion 303 and sample bottle light path position regulator 105, rearmounted polariscope 403, between sample bottle light path position regulator 105 and emergent light intensity, displacement detecting apparatus 106, and is connected with rotatable cabin 201 bottoms; Electronic capstan (402) can exchange with the position of rearmounted polariscope (403).
As shown in Figure 5, sample bottle light path position regulator 105 is positioned at rotatable cabin 201, between preposition polariscope 401 and rearmounted polariscope 403, mainly formed by left and right fixed support 501, bottle clip plate degree of tilt adjusting bracket 502, left and right bottle clip plate 503, bottle clip plate screw rod 504, the bottle clip plate screw rod 505 that moves to left that moves to right; Bottle clip plate degree of tilt adjusting bracket 502 is positioned at left and right fixed support 501 inner sides, left and right bottle clip plate 503 is positioned in the middle of bottle clip plate degree of tilt adjusting bracket 502, its left and right bottle clip plate 503 Lower Halves respectively have corresponding axis hole and screw, bottle clip plate screw rod 504 and bottle clip plate screw rod 505 near-ends that move to left that move to right are polished rod, far-end is bolt, in point corresponding axis hole and screw on left and right fixed support 501, bottle clip plate degree of tilt adjusting bracket 502 and left and right bottle clip plate 503 in left and right, left and right bottle clip plate 503 is regulated in poly-fixing.
As shown in Figure 6, emergent light intensity, displacement detecting apparatus 106 are positioned at rotatable cabin 201, are mainly made up of photelectric receiver 601, linear motion system 602; Photelectric receiver 601 is fixed on linear motion system 602, and can be shifted with linear motion system 602, and its transmission line passes with control system 107 and is connected through left rotation and right rotation support tubular shaft 202 center pits; Photelectric receiver 601 can be photoelectric cell, photoelectric tube, PSD displacement detector, line array CCD or area array CCD; Emergent light intensity, displacement detecting apparatus 106 also can adopt PSD displacement detector to replace.
When detection, first make rotatable cabin 201 go to normotopia, put into sample bottle by sample bottle hatchcover 203, close bottle hatchcover 203, rotation left and right bottle clip plate displacement screw rod 504, 505, during sample bottle is poly-, fix and be adjusted to the hot spot penetrating through the side opening of rearmounted polariscope 403 and get to the hot spot setting position of sample bottle light path position detection window 204, open and measure, photelectric receiver 601 centre bits move to emergent light dot center coincidence position from zero point with linear motion system 602, electronic capstan 402 starts to drive polariscope 401 to rotate a circle from zero point, just automatically determine the optical activity of carrier fluid position, absorbance log value, then the thumb wheel that rotates striking gear 205 makes rotatable cabin 201 go to the position of standing upside down, repeat aforesaid operations, just automatically determine the facula position irrelevance of empty bottle position optical activity, absorbance log value and twice mensuration position, automatically differ from formula computing and processing through system, just obtain absorbance, optical activity, the refractive index value of sample in bottle outlet.
Described control system 107 is arranged on the bottom of system fixed support 101, is mainly made up of kinetic control system, electrical apparatus control system, temperature control system, Photoelectric Detection disposal system, touch-screen, supply unit.