CN103736146A - Method for preparing silver-loaded non-woven fabric - Google Patents
Method for preparing silver-loaded non-woven fabric Download PDFInfo
- Publication number
- CN103736146A CN103736146A CN201310713195.XA CN201310713195A CN103736146A CN 103736146 A CN103736146 A CN 103736146A CN 201310713195 A CN201310713195 A CN 201310713195A CN 103736146 A CN103736146 A CN 103736146A
- Authority
- CN
- China
- Prior art keywords
- silver
- fibers
- alginate
- colored
- fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052709 silver Inorganic materials 0.000 title claims abstract description 22
- 239000004332 silver Substances 0.000 title claims abstract description 22
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 title claims abstract description 21
- 239000004745 nonwoven fabric Substances 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title abstract description 4
- 239000000835 fiber Substances 0.000 claims abstract description 21
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000010443 alginic acid Nutrition 0.000 claims abstract description 14
- 229920000615 alginic acid Polymers 0.000 claims abstract description 14
- 229940072056 alginate Drugs 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 238000001035 drying Methods 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims abstract description 11
- 239000000648 calcium alginate Substances 0.000 claims abstract description 10
- 235000010410 calcium alginate Nutrition 0.000 claims abstract description 10
- 229960002681 calcium alginate Drugs 0.000 claims abstract description 10
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims abstract description 10
- 238000009960 carding Methods 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims abstract description 4
- 238000002360 preparation method Methods 0.000 claims description 8
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims description 5
- 230000018044 dehydration Effects 0.000 claims description 5
- 238000006297 dehydration reaction Methods 0.000 claims description 5
- 239000004744 fabric Substances 0.000 claims description 5
- 238000001467 acupuncture Methods 0.000 claims description 3
- 230000001427 coherent effect Effects 0.000 claims description 3
- 229920001817 Agar Polymers 0.000 abstract 1
- 239000008272 agar Substances 0.000 abstract 1
- -1 silver ions Chemical class 0.000 abstract 1
- 238000009987 spinning Methods 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 17
- 208000027418 Wounds and injury Diseases 0.000 description 17
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- 230000029663 wound healing Effects 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 229910001424 calcium ion Inorganic materials 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 206010021143 Hypoxia Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 230000007954 hypoxia Effects 0.000 description 2
- 230000001473 noxious effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108010074860 Factor Xa Proteins 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000012984 antibiotic solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000028659 discharge Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 230000003448 neutrophilic effect Effects 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 208000012313 wound discharge Diseases 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a method for preparing a silver-loaded non-woven fabric. The method comprises the following steps: carding 1kg of an alginate base material into orderly fibers by a carding machine; immersing into a silver solution with the concentration of 1,600ug/ml in a mass ratio of 1:8, properly stirring, and taking out until the silver ions are sufficiently enriched onto the fibers; centrifugally drying in a spinning manner for 4-8 minutes by using a spin-dryer until the fibers are in a dry state, and dehydrating for 3-5 minutes with 95 percent ethanol; baking with a drier to obtain fluffy and soft agar fibers; uniformly mixing the baked calcium alginate silver fibers and pure calcium alginate staple fibers in a ratio of 1:1; opening, needling and slitting to obtain silver-loaded medical non-woven fabric with silver content of about 12,000mg/g.
Description
Technical field
The present invention relates to the preparation method of a kind of year silver-colored non-woven fabrics.
Background technology
Wound healing is the prerequisite of body function rehabilitation after wound, therefore accelerates wound healing research particularly important, to the development of Wound dressing, is wherein one of focus of research.New pattern compress is also referred to as active dressing or revolutionary dressing.Within 1962, doctor Winter obtains in the experiment of animal (pig).WINTET finds, under airtight moist environment, to be exposed to air drying wound surface fast again for speed of wound healing ratio.Thereby established the theoretical basis that adopts the processing wound surface of new pattern compress.The moisture retention bearing hydrocolloid dressing of the first generation until the eighties has just been born.The nineties is along with the development of material technology, and having produced the multiple different phase according to wound has the not dressing of same-action.Alginate dressing is the algin extracting in the brown algae of natural preciousness, be a kind of fibrid element do not dissolve polysaccharide, in manufacturing process, be converted into a kind of calcium salt, when contacting with wound exudate, can exchange by interionic, make indissolubility alginate calcium become solubility sodium alginate, and discharge calcium, there is extremely strong absorbability, can absorb quite and the liquid of 20 times of own wts, this has guaranteed wound wet union environment, extend and change dressings the time, make the slough self-dissolving in wound simultaneously, calcium ion in alginate forms one deck network gel in wound surface and helps lend some impetus to hemostasis.Along with calcium alginate dressing application clinically, the time shorten of wound repair, wound infection rate has reduced, and improved cure rate, alleviated patient's misery, correspondingly saved patient medical funds, especially the patient Ke family of chronic ulcer is changed dressings, increased patient's compliance.Because silver has adsorption to the microorganism in liquid, after microorganism is adsorbed by silver, play respiratory enzyme and just lose effect, microorganism will be dead rapidly.Utilize forward position nanotechnology by silver nanoparticle, make the sterilizing ability of silver under nanometer state produce qualitative leap, few nanometer silver can produce powerful bactericidal action, nanometer silver is added in product, the product of anti-microbial property of itself not having produces new technical ability, and this has to say a kind of lifting to product itself.The enterprise that current domestic enterprise sets foot in calcium alginate dressing is less, relates to and carries the just more very few of silver-colored alginate dressing, and according to medical apparatus and instruments registration certification database displaying, it is all that this type of certification is mostly foreign enterprise.
Summary of the invention
The invention provides the preparation method of a kind of year silver-colored non-woven fabrics, it utilizes the powerful bactericidal action of nanometer silver, by the killing bacteria that may grow along with time or wound in dressing, thereby has effectively prevented cross infection.
The present invention has adopted following technical scheme: the preparation method of a kind of year silver-colored non-woven fabrics, it comprises the following steps: 1kg alginate base material is carded to coherent fiber with carding machine, then the mass ratio with 1:8 is impregnated in the silver-colored solution of concentration 1600ug/ml, stir in good time, treat that silver ion is fully enriched on fiber, take out, drier centrifuge dripping 4min ~ 8min is as for drying regime, use again 95% ethanol dehydration 3min ~ 5min, drying machine drying, obtain the alginate fibre of fluffy softness, calcium alginate silver fiber and the pure calcium alginate short fiber of having dried are evenly mixed according to 1:1, carry out shredding, acupuncture, cut, obtain the silver-colored medical adhesive-bonded fabric that carries that silver content is about 12000mg/g.
The time of described drier centrifuge dripping is that 4min is as for drying regime.Described use 95% ethanol dehydration 3min.
The present invention has following beneficial effect: adopted after above technical scheme, the present invention not only has high-hygroscopicity, alginate medical films can absorb 11 times of liquid that are equivalent to own wt, and have hemostatic: the sepage of alginate medical films contact wound discharges Ca2+, can promote the formation of thrombokinase, accelerate blood clotting process, also there is into colloidality simultaneously: absorbing wound exudate, there is Na+/Ca2+ ion exchange with sepage, on wound surface, form the stable network gel of one deck.For wound is built a microenvironment (micro-acid, anaerobic or hypoxia, appropriate moistening) that is beneficial to tissue growth, promote wound healing: micro-acid, anaerobic or hypoxia, the moistening wound environment of appropriateness promote growth factor release, stimulate cellular proliferation, improve regeneration capacity and the signaling of epidermis cell, promote wound healing.1., good airproof performance the present invention has biocidal property:, make wound and extraneous antibacterial isolated; 2., noxious bacteria is fixed on fibrous inside, silver ion has effectively suppressed noxious bacteria breeding and has reduced the chance that antibacterial contacts with wound surface; 3., environment moistening, micro-acid is conducive to neutrophilic granulocyte and plays a role, enhancing local bactericidal ability, reduction infection rate.The present invention can reduce cicatrization: due to non-stimulated to wound surface, not damaged, so cicatrization is few.
The specific embodiment
Below by embodiment, further illustrate technical scheme of the present invention.
Embodiment mono-, the preparation method of a kind of year silver-colored non-woven fabrics of the present invention, it comprises the following steps: 1kg alginate base material is carded to coherent fiber with carding machine, then the mass ratio with 1:8 is impregnated in the silver-colored solution of concentration 1600ug/ml, stir in good time, treat that silver ion is fully enriched on fiber, take out, drier centrifuge dripping 4min is as for drying regime, use again 95% ethanol dehydration 3min, drying machine drying, obtain the alginate fibre of fluffy softness, calcium alginate silver fiber and the pure calcium alginate short fiber of having dried are evenly mixed according to 1:1, carry out shredding, acupuncture, cut, obtain the silver-colored medical adhesive-bonded fabric that carries that silver content is about 12000mg/g.
The silver-ion antibiotic solution that the present invention adopts, its combination is carried silver-colored non-woven fabrics antibacterial action and is determined as follows: antibiotic fabric is containing antibacterial concentration 12000ppm, and it is mainly gram positive bacteria that strain is selected in test, as staphylococcus aureus; Holland type negative bacterium, as escherichia coli; And Candida albicans, culture medium adopts nutrient broth medium and nutrient agar.
Antibiotic fabric antibacterial test method: GB/T 20944.3 succusions
Test result is as follows:
| ? | Escherichia coli | Staphylococcus aureus | Candida albicans |
| Sterilizing rate | 97.5% | 99.1% | 100% |
Alginate, gauze, gel rubber material, foam and combination in any thereof are contained in the dressing that base material of the present invention forms, the dressing that base material of the present invention forms contains bar shaped dressing, the dressing of rope shape, paste shape dressing with and combination in any, the dressing that base material of the present invention forms contain homogeneous monolayer, multilamellar, rope shape, paste shape with and combination in any.The concentration of nanometer silver of the present invention and the amount of base material are certain functional relationship, and nanometer silver solution is adsorbed onto on base material to some extent.
Claims (3)
1. carry a preparation method for silver-colored non-woven fabrics, it comprises the following steps:
1kg alginate base material is carded to coherent fiber with carding machine, then the mass ratio with 1:8 is impregnated in the silver-colored solution of concentration 1600ug/ml, stir in good time, treat that silver ion is fully enriched on fiber, take out, drier centrifuge dripping 4min ~ 8min is as for drying regime, use again 95% ethanol dehydration 3min ~ 5min, drying machine drying, obtain the alginate fibre of fluffy softness, calcium alginate silver fiber and the pure calcium alginate short fiber of having dried are evenly mixed according to 1:1, carry out shredding, acupuncture, cut, obtain the silver-colored medical adhesive-bonded fabric that carries that silver content is about 12000mg/g.
2. the preparation method of according to claim 1 year silver-colored non-woven fabrics, is characterized in that the time of described drier centrifuge dripping is that 4min is as for drying regime.
3. the preparation method of according to claim 1 year silver-colored non-woven fabrics, is characterized in that described use 95% ethanol dehydration 3min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310713195.XA CN103736146B (en) | 2013-12-22 | 2013-12-22 | Method for preparing silver-loaded non-woven fabric |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310713195.XA CN103736146B (en) | 2013-12-22 | 2013-12-22 | Method for preparing silver-loaded non-woven fabric |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103736146A true CN103736146A (en) | 2014-04-23 |
| CN103736146B CN103736146B (en) | 2017-04-12 |
Family
ID=50493258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310713195.XA Active CN103736146B (en) | 2013-12-22 | 2013-12-22 | Method for preparing silver-loaded non-woven fabric |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103736146B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104179033A (en) * | 2014-08-01 | 2014-12-03 | 陕西科技大学 | Production method of functional synthetic leather for mobile phone case |
| CN105463700A (en) * | 2015-12-18 | 2016-04-06 | 厦门百美特生物材料科技有限公司 | Spunlace alginate dressing |
| CN107899061A (en) * | 2017-11-13 | 2018-04-13 | 广东泰宝医疗科技股份有限公司 | A kind of alginates wound repair dressing and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019795A1 (en) * | 1994-01-20 | 1995-07-27 | Bristol-Myers Squibb Company | Wound dressing |
| CN1935268A (en) * | 2006-10-18 | 2007-03-28 | 上海川本卫生材料有限公司 | Nano silver calcium alginate antibacterial dressing |
| CN101721734A (en) * | 2008-10-22 | 2010-06-09 | 威海威高创新有限公司 | Medical calcium alginate antiseptic dressing and preparation method thereof |
| CN102505461A (en) * | 2011-10-28 | 2012-06-20 | 褚省吾 | Preparation method for silver-loaded calcium alginate fiber or silver-loaded medical non-woven fabric |
| CN103074703A (en) * | 2012-12-03 | 2013-05-01 | 佛山市优特医疗科技有限公司 | Antibacterial silver-containing fiber wound dressing and preparation method thereof |
| GB2496310A (en) * | 2011-11-01 | 2013-05-08 | Brightwake Ltd | Yarn and textile material for wound dressings |
-
2013
- 2013-12-22 CN CN201310713195.XA patent/CN103736146B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019795A1 (en) * | 1994-01-20 | 1995-07-27 | Bristol-Myers Squibb Company | Wound dressing |
| CN1935268A (en) * | 2006-10-18 | 2007-03-28 | 上海川本卫生材料有限公司 | Nano silver calcium alginate antibacterial dressing |
| CN101721734A (en) * | 2008-10-22 | 2010-06-09 | 威海威高创新有限公司 | Medical calcium alginate antiseptic dressing and preparation method thereof |
| CN102505461A (en) * | 2011-10-28 | 2012-06-20 | 褚省吾 | Preparation method for silver-loaded calcium alginate fiber or silver-loaded medical non-woven fabric |
| GB2496310A (en) * | 2011-11-01 | 2013-05-08 | Brightwake Ltd | Yarn and textile material for wound dressings |
| CN103074703A (en) * | 2012-12-03 | 2013-05-01 | 佛山市优特医疗科技有限公司 | Antibacterial silver-containing fiber wound dressing and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104179033A (en) * | 2014-08-01 | 2014-12-03 | 陕西科技大学 | Production method of functional synthetic leather for mobile phone case |
| CN104179033B (en) * | 2014-08-01 | 2016-07-20 | 陕西科技大学 | A kind of cell-phone cover production method of functional synthetic leather |
| CN105463700A (en) * | 2015-12-18 | 2016-04-06 | 厦门百美特生物材料科技有限公司 | Spunlace alginate dressing |
| CN107899061A (en) * | 2017-11-13 | 2018-04-13 | 广东泰宝医疗科技股份有限公司 | A kind of alginates wound repair dressing and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103736146B (en) | 2017-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110354295B (en) | Photo-thermal conversion material and preparation method thereof | |
| CN101708341B (en) | Method for preparing Ag-carrying bacterial cellulose hydrogel antimicrobial dressing and product thereof | |
| WO2019091150A1 (en) | Alginate wound repair dressing and preparation method thereof | |
| Lin et al. | Evaluation of silver‐containing activated carbon fiber for wound healing study: in vitro and in vivo | |
| CN101905031B (en) | Method for preparing flamazine/bacterial cellulose composite wound dressing | |
| CN111617309B (en) | Antibacterial hemostatic sponge and preparation method thereof | |
| CN101927029B (en) | Preparation method of chitosan/polyvinyl alcohol sponge dressing containing nano-silver | |
| RU149063U1 (en) | ANTI-MICROBIAL ACTION BAND FOR HEALING | |
| CN104623718B (en) | Chitosan petrolatum gauze and preparation method thereof | |
| CN104069537A (en) | Sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and preparation method thereof | |
| CN104623722A (en) | Alginic acid antibacterial hemostatic sponge material and preparation method thereof | |
| CN106110383A (en) | A kind of chitosan alginate dressing and freeze-drying process thereof | |
| CN107137748B (en) | Core-shell electrostatic spinning chitosan nanofiber wound dressing and preparation method thereof | |
| CN104231299A (en) | Preparation method of silver-loaded meso-porous silicon/collagen/polyvinyl acetal antimicrobial dressing | |
| CN105664225A (en) | Nano-silver, chitosan and fibroin compound biological dressing and preparation method thereof | |
| CN107469128A (en) | A kind of antimicrobial form alginates complex function dressing and preparation method thereof | |
| CN108969791B (en) | Composite wound dressing loaded with nano-silver and preparation method thereof | |
| CN103736146B (en) | Method for preparing silver-loaded non-woven fabric | |
| CN106344954A (en) | Bio-antimicrobial bacterial cellulose dressing and preparation method thereof | |
| CN105126150A (en) | Adhesive bandage containing chitosan mixture and preparation method of adhesive bandage | |
| CN114343975A (en) | Wet wound dressing and its prepn | |
| CN106983903B (en) | Wet dressing with acid-base indication function and preparation method thereof | |
| CN106729940B (en) | Slow-release long-acting antibacterial silver-loaded dressing and preparation method thereof | |
| WO2019056819A1 (en) | Collagen-loaded alginate medical dressing and preparation method therefor | |
| CN109276748A (en) | One kind prevents adhesion promoting healing antibacterial bearing hydrocolloid dressing and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171214 Address after: 225321 Taizhou, Jiangsu Port Industrial Park, Far East Avenue, No. 8 Patentee after: ROOSIN MEDICAL CO., LTD. Address before: 225321 Taizhou, Jiangsu Port Industrial Park, Far East Avenue, No. 8 Patentee before: Chu Jiamian |
|
| TR01 | Transfer of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A method of preparing non-woven fabric with silver Effective date of registration: 20201116 Granted publication date: 20170412 Pledgee: Bank of Nanjing Co., Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT Co.,Ltd. Registration number: Y2020980008040 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20211227 Granted publication date: 20170412 Pledgee: Bank of Nanjing Co., Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT CO.,LTD. Registration number: Y2020980008040 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of silver loaded non-woven fabric Effective date of registration: 20211229 Granted publication date: 20170412 Pledgee: Bank of Nanjing Co., Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT CO.,LTD. Registration number: Y2021980016868 |