CN103720924B - One treats dysmenorrhea external omphaloidean ointment - Google Patents
One treats dysmenorrhea external omphaloidean ointment Download PDFInfo
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- CN103720924B CN103720924B CN201410019742.9A CN201410019742A CN103720924B CN 103720924 B CN103720924 B CN 103720924B CN 201410019742 A CN201410019742 A CN 201410019742A CN 103720924 B CN103720924 B CN 103720924B
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Abstract
The present invention relates to a kind of compositions and preparation method for the treatment of dysmenorrhea external omphaloidean ointment.Solve existing deficiency of taking orally with topical class Chinese medicine composition and physics mode treatment dysmenorrhea.Used by inner disease outer treat that dispelling cold and removing dampness dispels the wind, the Chinese medicine of dredge the meridian passage forms the present composition, thus replace the dysmenorrhea treatment scheme always continued to use at present and medication.The present invention by: Radix Flemingiae Philippinensis 5-30 part, Rhizoma Drynariae 6-30 part, Radix Cynanchi Paniculati 5-30 part, Radix Gentianae Macrophyllae 7-30 part, Fructus Chaenomelis 5-30 part, Radix Angelicae Pubescentis 5-30 part, Herba speranskiae tuberculatae 6-30 part, Herba Lycopodii 5-30 part, Caulis Fissistigmatis 8-30 part, Folium Clerodendri Trichotomi 7-30 Fen, Herba Siegesbeckiae 9-30 part, Borneolum Syntheticum 1-5 part, azone 1 part are prepared from.Treatment dysmenorrhea external omphaloidean ointment provided by the invention, has good absorbing, instant effect, and can eliminate or alleviate various types of dysmenorrhea symptom fast, treatment cycle is short, evident in efficacy, and raw material is easy to get, and prepares the advantages such as simple.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to a kind of external omphaloidean ointment for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea is one of common gynecological disease, refers to that women is on the occasion of menstrual period or front and back of passing through, and occurs periodically hypogastric region distending pain, cold type of pain, causalgia, twinge, dull pain, pendant pain, angor, spasmic pain, lancinating pain etc.Some patient often, dripping cold sweat, severe patient as ice-cold in distending pain of the breast, rectal tenesmus, the soreness of waist, nausea and vomiting, extremity with General Symptoms can collapse and faint.Dysmenorrhea can be divided into primary dysmenorrhea and secondary dysmenorrhea clinically, Young Female dysmenorrhea, and great majority are that primary dysmenorrhea is commonplace.Start the adult female's dysmenorrhea had sexual intercourse especially, majority is secondary dysmenorrhea.Primary dysmenorrhea should be attributed to following several cause of disease: inner membrance cast comes off (membranous dysmenorrhea), bad body provides and body constitution, allergy state and Nervous and Mental Factors etc.Secondary dysmenorrhea is that genitals has obvious pathological changes person such as the diseases such as tumor such as adenomyosis, chocolate cyst, pelvic inflammatory disease, subserous myoma to cause mostly.The sickness rate of the secondary dysmenorrhea that continues at present continues to increase, and has to draw attention.
Before the present invention does not file an application, the method such as principle many dependence promoting blood flow to regulate menstruation, regulating qi to disperse stagnation pain relieving, dispelling cold by warming the meridian of Chinese medicine treating difficult menstruation.Chinese medicine used is mainly with Pollen Typhae, Oletum Trogopterori, Sanguis Draxonis, Rhizoma Corydalis, Herba Leonuri, Squama Manis, Flos Carthami, Olibanum, Myrrha, Semen Persicae, Fructus Foeniculi, Folium Artemisiae Argyi, Radix Notoginseng, Radix Paeoniae Rubra etc.These Chinese Herbs for oral administration are not well, the easily side effect such as stimulating gastrointestinal road yet, and the cost price of every day is higher.The mode of current inner disease outer treat treatment dysmenorrhea is also a lot, is processed into muffin or refines to concentrate make various types of patch with foregoing Chinese medicine etc.Also have exactly by physics mode or utilize chemical substance to react to each other and make various types of health-care patch or bag, their principle is to produce certain temperature to promote that the inner blood circulation in uterus is to improve dysmenorrhea.But, they just have certain remission effect to primary dysmenorrhea, and just obviously bad to the therapeutical effect of the secondary dysmenorrhea that continues due to illness caused.
Summary of the invention
The object of this invention is to provide one and treat dysmenorrhea external omphaloidean ointment, solve the defect existed in prior art, can eliminate fast or alleviate Secondary cases and primary dysmenorrhea, there is good absorbing, instant effect, treatment cycle is short, evident in efficacy, raw material is easy to get, with low cost, prepares the advantages such as simple.
The technical solution adopted in the present invention is:
One treats dysmenorrhea external omphaloidean ointment compositions, and it has one for the crude drug of the following parts by weight of etiology and pathology and pharmacology: Radix Flemingiae Philippinensis 50-90 part, Rhizoma Drynariae 60-97 part, Radix Cynanchi Paniculati 50-95 part, Radix Gentianae Macrophyllae 70-130 part, Fructus Chaenomelis 50-90 part, Radix Angelicae Pubescentis 50-95 part, Herba speranskiae tuberculatae 60-94 part, Herba Lycopodii 80-130 part, Caulis Fissistigmatis 80-130 part, Folium Clerodendri Trichotomi 70-130 Fen, Herba Siegesbeckiae 90-150 part, Borneolum Syntheticum 5-30 part, azone 1-10 part.
Improve further as to the present invention, described treatment dysmenorrhea external omphaloidean ointment comprises following parts by weight crude drug: Radix Flemingiae Philippinensis 70 parts, Rhizoma Drynariae 80 parts, Radix Cynanchi Paniculati 70 parts, Radix Gentianae Macrophyllae 80 parts, Fructus Chaenomelis 60 parts, Radix Angelicae Pubescentis 70 parts, Herba speranskiae tuberculatae 75 parts, Herba Lycopodii 110 parts, Caulis Fissistigmatis 90 parts, Folium Clerodendri Trichotomi 80 Fen, Herba Siegesbeckiae 95 parts, Borneolum Syntheticum 5 parts, azone 1 part.
It has a meticulous manufacture method:
Except Borneolum Syntheticum, azone two taste, by other 11 kinds of Chinese medicines according to parts by weight, after the water soaking 1 little time adding 5 times, then add the soak by water 3 hours of 6 times, filter, filtering residue.Add the soak by water 3 hours of 6 times again, filter, filtering residue, merge secondary filtrate, continue to decoct and be concentrated into extractum (relative density is 1.03)
Under the extractum be condensed into is positioned over room temperature, adds 1 part of Borneolum Syntheticum and 1 part of medical chlorine ketone, be stirred into cream gently for subsequent use.
By machine or be manually coated in every block length 10cm respectively, on the special extractum plaster of rectangle of the cotton block of wide 6cm, with for subsequent use.
Separately used by the extractum be condensed into 10g bottle package encapsulation for subsequent use more respectively, or it is for subsequent use to make cone shape medicated core.
The invention has the beneficial effects as follows: the present invention dispels the wind with dispelling cold and removing dampness, the Chinese medicine of dredge the meridian passage is formed the present composition, this is the compositions being different from current existing treatment dysmenorrhea.Because the tcm causa morbi great majority that menalgia is formed are that " cold womb " directly causes, " cold womb " contains this three pathogen of wind, cold, wet simultaneously in fact.According to the theory of TCM: extraneous this three pathogen of wind, cold, wet enters human body mainly through 5 passages: " DAZHUI acupoint " of 1. takeing on cervical region." SHANZHONG acupoint " of 2. shirtfront." SHENQUE acupoint " at 3. umbilicus position." MINGMEN acupoint " of 4. waist." Yongquan acupoint " of 5. sole." wind and cold wets " that enter from " SHENQUE acupoint " is easily accumulated in our pelvic cavity, particularly woman, when Intrapelvic " cold-damp gas " is heavy, just easily cause the various disease of our gynecological, such as gynecological inflammation, menoxenia, menses be smooth, dysmenorrhea, clot, hysteromyoma, ovarian cyst, sterility and infertility etc.We can prove with a simple example in fact, can be easier to understand, and we are placed on the place of " dark moist " one block of wood, and this block wood is easy to go bad, mouldy, long mill is eaten.If the uterus of we woman, ovary are placed in such " cold-damp " pelvic cavity environment for a long time, just easily there is various disease in woman gynecological." void is then trembled with fear---and > is cold then to wet---and > is wet then to coagulate---the solidifying then stasis of blood of >---the > stasis of blood is then blocked up---> is stifled then obstructed---> stagnation of QI and blood may bring about pain ", so compositions of the present invention only uses, dispelling cold and removing dampness dispels the wind, the Chinese medicine of dredge the meridian passage, just can reach treating both the principal and secondary aspects of a disease effect for the treatment of primary dysmenorrhea and secondary dysmenorrhea.In order to reduce these Chinese medicines for oral administration may to the discomfort of the aspects such as health gastrointestinal, so the profit special construction of inner disease outer treat and umbilical part, and select medicine for external use in umbilical part.The present composition also break traditions Chinese traditional treatment dysmenorrhea with " blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dispelling cold by warming the meridian " principle and the old rule of medication.Do not need the Chinese medicine adding strong pain relieving in the present composition, also do not treat dysmenorrhea with the Chinese medicine of blood circulation promoting and blood stasis dispelling or circulation of qi promoting, but selection dispelling cold and removing dampness dispels the wind, the Chinese medicine of dredge the meridian passage reaches treatment dysmenorrhea object.Break medication thought and the principle of front human therapy dysmenorrhea, explore the thinking of another characteristic treatment dysmenorrhea.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in detail, it should be understood that these embodiments are only for purpose of illustration, determine not limit the scope of the invention.
Embodiment one dysmenorrhea external omphaloidean ointment.
Take Radix Flemingiae Philippinensis 80 parts, Rhizoma Drynariae 90 parts, Radix Cynanchi Paniculati 82 parts, Radix Gentianae Macrophyllae 87 parts, Fructus Chaenomelis 69 parts, Radix Angelicae Pubescentis 78 parts, Herba speranskiae tuberculatae 80 parts, Herba Lycopodii 90 parts, Caulis Fissistigmatis 80 parts, Folium Clerodendri Trichotomi 70 Fen, Herba Siegesbeckiae 96 parts, Borneolum Syntheticum 2 parts, azone 1 part.Preparation method: except Borneolum Syntheticum, azone two taste, by other 11 kinds of Chinese medicines according to parts by weight, after the water soaking 1 little time adding 5 times, then adds the soak by water 3 hours of 6 times, filters, filtering residue.Add the soak by water 3 hours of 6 times again, filter, filtering residue, merge secondary filtrate, continue to decoct and be concentrated into extractum (relative density is 1.03).Under the extractum be condensed into is positioned over room temperature, add 2 parts of Borneolum Syntheticums and 1 part of medical chlorine ketone, stir into gently and evenly become cream for subsequent use.By machine or be manually coated in every block length 10cm respectively, on the special extractum plaster of rectangle of the cotton block of wide 6cm, with for subsequent use.Separately again the extractum be condensed into is packed for subsequent use with 10g bottle respectively, or it is for subsequent use to make cone shape medicated core.
Except Borneolum Syntheticum and azone have transdermal effect in the composition in the present embodiment one compositions, skin pore expansion can be increased, be beneficial to the effective ingredient rapid osmotic of medicine, and Borneolum Syntheticum can also increase the function of pain relieving.Other Radix Flemingiae Philippinensis, Rhizoma Drynariae, Radix Cynanchi Paniculati, Radix Gentianae Macrophyllae, Fructus Chaenomelis, Radix Angelicae Pubescentis, Herba speranskiae tuberculatae, Herba Lycopodii, Caulis Fissistigmatis, Folium Clerodendri Trichotomi, Herba Siegesbeckiae all have functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage effect.According to modern pharmacology analysis, these functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage class Chinese medicine have good anti-inflammatory analgesic, improve the effect of smooth muscle spasm, therefore can have co-therapy effect to primary dysmenorrhea and secondary dysmenorrhea.
Function and curing mainly: functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage, suitablely cures mainly all types of dysmenorrhea (constitutional or secondary dysmenorrhea).
Use the course for the treatment of: starting every day uses once to have dysmenorrhea to feel, continuous was a course for the treatment of with three days.
Consumption and consumption: bring into use when dysmenorrhea is come, can prove effective, and preferably feels front use just before going to bed in every day, must open plaster, to allow skin permeability to the second afternoon about 2.As having infringement to skin, can every one day with a plaster.General selection face start evening paste, first extract with clean warm towel, clean up in navel gently, then open giving a bottle that 10 grams of unguentum are housed as an addition, dysmenorrhea unguentum in bottle is dipped in a little with the cotton swab given as an addition, navel bosom and wall surrounding are filled this unguentum, at this moment the release paper taking out a rectangle plaster is again torn, (necessarily by perpendicular for rectangle cream pad subsides) on navel is affixed on by with overflow-proof ring and the rectangle being stained with plaster cotton block one side are perpendicular, " navel " (SHENQUE acupoint) is allowed to aim at upper 1/3rd places of the cotton block of setting rectangle.Necessarily remember: morning will be forgotten scarcely after getting up and opens plaster side gently, put into navel a little with the unguentum that cotton swab dips in bottle again and increase dose, because evening before that day put into the unguentum of navel, absorbed by the skin at a night, having arrived morning does not just have what yet.So again unguentum must be inserted in navel).
User must while each rectangle plaster pasted on umbilicus, also must be affixed on (the navel parallel alignment position approximately and before human body, lumbar vertebra position by perpendicular for the rectangle plaster of a cotton block of band again, this is the MINGMEN acupoint in Chinese medicine acupuncture), also directly can be affixed on the lumbar vertebra place at soreness of waist position when menstruation comes by heavily fortified point.Difference is exactly need not at the first paste of lumbar vertebra, but is directly affixed on lumbar vertebra place then can perpendicular for plaster.
Points for attention: 1, this product is only for external application, forbid taking orally; 2, skin allergy person is cautious use of, and forbids for skin injury position person.3, place child getting in contact less than place; 4, because umbilical part unguentum has functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage effect, so anemia of pregnant woman's forbidding; If 5 force on after local skin there is pimple or serious pruritus, illustrates that patient is to this plaster allergy, should stop using immediately.6, after having a bath, affected part can not be affixed on immediately, can paste again after half an hour.
The present invention is used for the treatment of dysmenorrhea patient 200 example and carries out clinical observation treatment.Wherein age those at least 13 years old, the maximum 49 years old, 27 years old mean age: wherein without sexual life person 72 example, sexual intercourse person 128 example: the course of disease 2 months ~ 20 years.Primary dysmenorrhea 72 example is divided, secondary dysmenorrhea 128 example according to the type of dysmenorrhea.Severe 86 example is divided, moderate 74 example, slight 40 examples according to pain degree.This group case is made a definite diagnosis through gynecologial examination and/B ultrasonic, gets rid of reproductive system organs's mechanical injuries in pelvic cavity.
Efficacy assessment standard: the present invention is used for the treatment of dysmenorrhea disease, " Chinese medical disease Standardization of diagnosis and curative effect " that its criterion of therapeutical effect is issued with reference to national traditional chinese medical science administration is formulated, and is divided into following three kinds:
Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.Heal in end: improvement is seen at pain end.
Therapeutic effect: after 2 courses for the treatment of, cures 88 examples, and take a turn for the better 107 examples, and end is 5 examples more, total effective rate 97.5%.A course for the treatment of of light moderate patient external, Most patients transference cure, minority is an external just transference cure course for the treatment of again.Severe pain is after 3 courses for the treatment of of patient's external, and some patients transference cure, is cured, and most of patients is clearly better.For light moderate pain through patient, general to paste once just can obvious relieving dysmenorrhea degree, to paste after secondary just that relieving dysmenorrhea is not substantially bitterly or hypodynia.Severe pain through patient after first course for the treatment of of use, the degree of Most patients relieving dysmenorrhea.
Compared with prior art, the invention has the beneficial effects as follows: the present invention draws through groping summary in a large number according to the treatment dysmenorrhea principle of functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage, mutually synergism is there is by the Chinese medicine in compositions of the present invention, have and eliminate fast or relieving dysmenorrhea symptom, existing market same type of composition can be replaced completely.Simultaneously composition material of the present invention is easy to get, with low cost, preparation is simple, have no side effect, and can alleviate the advantages such as the financial burden of patient.
Claims (3)
1. treat a dysmenorrhea external omphaloidean ointment compositions, it is characterized in that: crude drug and parts by weight as follows: Radix Flemingiae Philippinensis 50-90 part, Rhizoma Drynariae 60-97 part, Radix Cynanchi Paniculati 50-95 part, Radix Gentianae Macrophyllae 70-130 part, Fructus Chaenomelis 50-90 part, Radix Angelicae Pubescentis 50-95 part, Herba speranskiae tuberculatae 60-94 part, Herba Lycopodii 80-130 part, Caulis Fissistigmatis 80-130 part, Folium Clerodendri Trichotomi 70-130 part, Herba Siegesbeckiae 90-150 part, Borneolum Syntheticum 5-30 part, azone 1-10 part.
2. one according to claim 1 treats dysmenorrhea external omphaloidean ointment compositions, it is characterized in that: Radix Flemingiae Philippinensis 70 parts, Rhizoma Drynariae 80 parts, Radix Cynanchi Paniculati 70 parts, Radix Gentianae Macrophyllae 80 parts, Fructus Chaenomelis 60 parts, Radix Angelicae Pubescentis 70 parts, Herba speranskiae tuberculatae 75 parts, Herba Lycopodii 110 parts, Caulis Fissistigmatis 90 parts, Folium Clerodendri Trichotomi 80 Fen, Herba Siegesbeckiae 95 parts, Borneolum Syntheticum 5 parts, azone 1 part.
3. one according to claim 1 and 2 treats dysmenorrhea external omphaloidean ointment compositions, it is characterized in that: manufacture method is:
1. except Borneolum Syntheticum, azone two taste, by other 11 kinds of Chinese medicines according to parts by weight, add the water soaking of 5 times after 1 hour, add the soak by water 3 hours of 6 times again, filter, filtering residue adds the soak by water 3 hours of 6 times again, filtration, filtering residue, merge secondary filtrate, continues to decoct to be concentrated into the extractum that extractum relative density is 1.03;
2. under the extractum be condensed into being positioned over room temperature, add 1 part of Borneolum Syntheticum and 1 part of medical chlorine ketone, stir into gently and evenly become cream for subsequent use;
3. by machine or be manually coated in every block length 10cm respectively, on the special extractum plaster of rectangle of the cotton block of wide 6cm, with for subsequent use;
4. separately used by the extractum be condensed into 10g bottle package encapsulation for subsequent use more respectively, or it is for subsequent use to make cone shape medicated core.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410019742.9A CN103720924B (en) | 2014-01-06 | 2014-01-06 | One treats dysmenorrhea external omphaloidean ointment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410019742.9A CN103720924B (en) | 2014-01-06 | 2014-01-06 | One treats dysmenorrhea external omphaloidean ointment |
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| CN103720924A CN103720924A (en) | 2014-04-16 |
| CN103720924B true CN103720924B (en) | 2016-03-16 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1181269A (en) * | 1997-12-01 | 1998-05-13 | 董锡山 | Pain relieving antiphlogistine and its prepn. method |
| CN101912572A (en) * | 2010-07-30 | 2010-12-15 | 崔宝海 | Multi-effect external plaster |
-
2014
- 2014-01-06 CN CN201410019742.9A patent/CN103720924B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1181269A (en) * | 1997-12-01 | 1998-05-13 | 董锡山 | Pain relieving antiphlogistine and its prepn. method |
| CN101912572A (en) * | 2010-07-30 | 2010-12-15 | 崔宝海 | Multi-effect external plaster |
Non-Patent Citations (2)
| Title |
|---|
| 内服外敷中药治疗风湿症1239例效果观察;韩树国;《承德医学院学报》;19980930(第03期);214-215 * |
| 温经止痛散;《医学文选》;19941030(第05期);40 * |
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