CN103720924A - External omphaloidean ointment for treating dysmenorrhea - Google Patents

External omphaloidean ointment for treating dysmenorrhea Download PDF

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CN103720924A
CN103720924A CN201410019742.9A CN201410019742A CN103720924A CN 103720924 A CN103720924 A CN 103720924A CN 201410019742 A CN201410019742 A CN 201410019742A CN 103720924 A CN103720924 A CN 103720924A
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parts
dysmenorrhea
external
treatment
radix
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CN103720924B (en
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王孝中
王长杰
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Abstract

The invention relates to an external omphaloidean ointment composition for treating dysmenorrhea and a preparation method thereof, and aims to solve the problem of deficiency for treating dysmenorrhea by an existing oral and external traditional Chinese medicinal compositions and a physical therapy mode. The composition is prepared from traditional Chinese medicines for dispelling cold, removing dampness and expelling wind, clearing and activating channels and collaterals according to the principle of treating internal illness by external treatment, so that the composition can replace current conventional dysmenorrhea treatment schemes and medicines. The external omphaloidean ointment is prepared from the following components in parts by weight: 5-30 parts of philippine flemingia root, 6-30 parts of rhzizoma drynariae, 5-30 parts of paniculate swallowwort root, 7-30 parts of large-leaved gentian, 5-30 parts of pawpaw, 5-30 parts of angelica pubescens, 6-30 parts of garden balsam stem, 5-30 parts of lycopodium clavatum, 8-30 parts of fissistigma polyanthum, 7-30 parts of harlequin glorybower leaf, 9-30 parts of herba siegesbeckiae, 1-5 parts of borneol, and 1 part of azone. The external omphaloidean ointment composition for treating dysmenorrhea has the advantages of good absorption, quick response, short course of treatment, remarkable curative effect, easily available raw materials, simple preparation and the like, and can be used for quickly eliminating or relieving various types of dysmenorrhea symptoms.

Description

A kind of dysmenorrhea umbilical part external plaster for the treatment of
Technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of umbilical part external plaster for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea is one of common gynecological disease, refers to women on the occasion of menstrual period or before and after passing through, occurs periodically hypogastric region distending pain, cold type of pain, causalgia, twinge, dull pain, pendant pain, angor, spasmic pain, lancinating pain etc.Some patient often, dripping cold sweat as ice-cold in distending pain of the breast, rectal tenesmus, the soreness of waist, nausea and vomiting, extremity with General Symptoms, severe patient can collapse and faints etc.Dysmenorrhea can be divided into primary dysmenorrhea and secondary dysmenorrhea clinically, Young Female dysmenorrhea, and great majority are that primary dysmenorrhea is commonplace.Start especially the adult female's dysmenorrhea having sexual intercourse, majority is secondary dysmenorrhea.Primary dysmenorrhea should be attributed to following several cause of disease: inner membrance cast comes off (membranous dysmenorrhea), bad body money and body constitution, allergy state and Nervous and Mental Factors etc.Secondary dysmenorrhea is that genitals has obvious pathological changes person to cause as diseases such as tumor such as adenomyosis, chocolate cyst, pelvic inflammatory disease, subserous myomas mostly.The sickness rate that continues at present the property sent out dysmenorrhea continues to increase, and has to draw attention.
Before the present invention does not file an application, the principle of Chinese medicine treating difficult menstruation relies on the methods such as promoting blood flow to regulate menstruation, regulating qi to disperse stagnation pain relieving, dispelling cold by warming the meridian more.Chinese medicine used is mainly with Pollen Typhae, Oletum Trogopterori, Sanguis Draxonis, Rhizoma Corydalis, Herba Leonuri, Squama Manis, Flos Carthami, Olibanum, Myrrha, Semen Persicae, Fructus Foeniculi, Folium Artemisiae Argyi, Radix Notoginseng, Radix Paeoniae Rubra etc.These Chinese Herbs for oral administration are not well, the also easily side effect such as stimulating gastrointestinal road, and the expense price of every day is higher.The mode of at present inner disease outer treat treatment dysmenorrhea is also a lot, with foregoing Chinese medicine etc., is processed into muffin or refines to concentrate and make various types of patch.Also have exactly by physics mode or utilize chemical substance to react to each other and make various types of health-care patchs or bag, their principle promotes the inner blood circulation in uterus to improve dysmenorrhea to produce certain temperature.But, they just have certain remission effect to primary dysmenorrhea, and just obviously bad to the therapeutical effect of the continuation property the sent out dysmenorrhea due to illness causing.
Summary of the invention
The object of this invention is to provide a kind of dysmenorrhea umbilical part external plaster for the treatment of, solved the defect existing in prior art, can eliminate fast or alleviate Secondary cases and primary dysmenorrhea, there is good absorbing, instant effect, treatment cycle is short, evident in efficacy, raw material is easy to get, with low cost, prepares the advantages such as simple.
The technical solution adopted in the present invention is:
Treat a dysmenorrhea umbilical part external plaster compositions, it has one for the crude drug of the following parts by weight of etiology and pathology and pharmacology: Radix Flemingiae Philippinensis 50-90 part, Rhizoma Drynariae 60-97 part, Radix Cynanchi Paniculati 50-95 part, Radix Gentianae Macrophyllae 70-130 part, Fructus Chaenomelis 50-90 part, Radix Angelicae Pubescentis 50-95 part, Herba speranskiae tuberculatae 60-94 part, Herba Lycopodii 80-130 part, Caulis Fissistigmatis 80-130 part, Folium Clerodendri Trichotomi 70-130 Fen, Herba Siegesbeckiae 90-150 part, Borneolum Syntheticum 5-30 part, azone 1-10 part.
As the present invention is further improved, described treatment dysmenorrhea umbilical part external plaster comprises following parts by weight crude drug: 70 parts of Radix Flemingiae Philippinensis, 80 parts of Rhizoma Drynariae, 70 parts of Radix Cynanchi Paniculatis, 80 parts of Radix Gentianae Macrophyllae, 60 parts of Fructus Chaenomeliss, 70 parts of Radix Angelicae Pubescentiss, 75 parts of Herba speranskiae tuberculataes, 110 parts of Herba Lycopodiis, 90 parts of Caulis Fissistigmatiss, Folium Clerodendri Trichotomi 80 95 parts of Fen, Herba Siegesbeckiaes, 5 parts of Borneolum Syntheticums, 1 part of azone.
It has a meticulous manufacture method:
Except Borneolum Syntheticum, azone two tastes, other 11 kinds of Chinese medicines, according to parts by weight, after adding between the water soaking 1 hour of 5 times, then are added to the decocting of 6 times and boil 3 hours, filter, filtering residue.The decocting that adds again 6 times boils 3 hours, filters, filtering residue, merges secondary filtrate, continues to decoct to be concentrated into extractum (relative density is 1.03)
The extractum being condensed into is positioned under room temperature, adds 1 part of Borneolum Syntheticum and 1 part of medical chlorine ketone, be stirred into gently cream standby.
By machine or be manually coated in respectively every block length 10cm, on the special-purpose extractum plaster of rectangle of the cotton piece of wide 6cm, with standby.
Separately again the extractum being condensed into is used respectively 10g bottle package encapsulation standby, or it is standby to make cone shape medicated core.
The invention has the beneficial effects as follows: the present invention with dispelling cold and removing dampness dispel the wind, the Chinese medicine of dredge the meridian passage forms the present composition, this is the compositions that is different from current existing treatment dysmenorrhea.Because the tcm causa morbi great majority that menalgia forms are that " cold womb " directly causes, " cold womb " comprised this three pathogen of wind, cold, wet simultaneously in fact.According to the theory of TCM: extraneous this three pathogen of wind, cold, wet mainly enters human body by 5 passages: " DAZHUI acupoint " of 1. takeing on cervical region.2. " SHANZHONG acupoint " of shirtfront.3. " SHENQUE acupoint " at umbilicus position.4. " MINGMEN acupoint " of waist.5. " Yongquan acupoint " of sole." wind and cold is wet " that from " SHENQUE acupoint ", enter easily stockpiles the pelvic cavity at us, woman particularly, when Intrapelvic " cold-damp gas " is heavy, just easily cause our gynecological's various diseases, such as gynecological inflammation, menoxenia, menses are smooth, dysmenorrhea, clot, hysteromyoma, ovarian cyst, sterility and infertility etc.We can prove with a simple example in fact, can be easier to understand, and we are placed on a wood in the place of " dark moist ", and this piece wood is easy to go bad, mouldy, long mill is eaten etc.If we woman's uterus, ovary are placed in such " cold-damp " pelvic cavity environment for a long time, just easily there is various diseases in woman gynecological." void is cold---and > is cold wet---and > is wet solidifying---the solidifying stasis of blood of >---the > stasis of blood is stifled---> is stifled obstructed---> stagnation of QI and blood may bring about pain ", so compositions of the present invention is only used, dispelling cold and removing dampness dispels the wind, the Chinese medicine of dredge the meridian passage, just can reach the treating both the principal and secondary aspects of a disease effect for the treatment of primary dysmenorrhea and secondary dysmenorrhea.In order to reduce the discomfort that these Chinese medicines for oral administration may be to aspects such as health gastrointestinals, then profit the special construction of inner disease outer treat and umbilical part, and be chosen in medicine for external use in umbilical part.The present composition also break traditions Chinese traditional treatment dysmenorrhea with " blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dispelling cold by warming the meridian " principle and the old rule of medication.In need to be in the present composition, add the Chinese medicine of strong pain relieving, also with the Chinese medicine of blood circulation promoting and blood stasis dispelling or circulation of qi promoting, do not treat dysmenorrhea, but select that dispelling cold and removing dampness dispels the wind, the Chinese medicine of dredge the meridian passage reaches treatment dysmenorrhea object.Break medication thought and the principle of front human therapy dysmenorrhea, explore the thinking of another characteristic treatment dysmenorrhea.
The specific embodiment
Below in conjunction with the specific embodiment, the present invention is described in detail, it should be understood that these embodiment, only for purpose of illustration, determine not limit the scope of the invention.
Embodiment mono-dysmenorrhea umbilical part external plaster.
Take 80 parts of Radix Flemingiae Philippinensis, 90 parts of Rhizoma Drynariae, 82 parts of Radix Cynanchi Paniculatis, 87 parts of Radix Gentianae Macrophyllae, 69 parts of Fructus Chaenomeliss, 78 parts of Radix Angelicae Pubescentiss, 80 parts of Herba speranskiae tuberculataes, 90 parts of Herba Lycopodiis, 80 parts of Caulis Fissistigmatiss, Folium Clerodendri Trichotomi 70 96 parts of Fen, Herba Siegesbeckiaes, 2 parts of Borneolum Syntheticums, 1 part of azone.Preparation method: except Borneolum Syntheticum, azone two tastes, other 11 kinds of Chinese medicines, according to parts by weight, after adding between the water soaking 1 hour of 5 times, then are added to the decocting of 6 times and boil 3 hours, filter, filtering residue.The decocting that adds again 6 times boils 3 hours, filters, filtering residue, merges secondary filtrate, continues to decoct to be concentrated into extractum (relative density is 1.03).The extractum being condensed into is positioned under room temperature, adds 2 parts of Borneolum Syntheticums and 1 part of medical chlorine ketone, stir into gently even one-tenth cream standby.By machine or be manually coated in respectively every block length 10cm, on the special-purpose extractum plaster of rectangle of the cotton piece of wide 6cm, with standby.Another the extractum being condensed into is packed respectively standbyly with 10g bottle, or it is standby to make cone shape medicated core again.
In the present embodiment one compositions, except Borneolum Syntheticum and azone have transdermal effect in compositions, skin pore expansion can be increased, be beneficial to the effective ingredient rapid osmotic of medicine, and Borneolum Syntheticum the function of pain relieving can also be increased.Other Radix Flemingiae Philippinensis, Rhizoma Drynariae, Radix Cynanchi Paniculati, Radix Gentianae Macrophyllae, Fructus Chaenomelis, Radix Angelicae Pubescentis, Herba speranskiae tuberculatae, Herba Lycopodii, Caulis Fissistigmatis, Folium Clerodendri Trichotomi, Herba Siegesbeckiae all have functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage effect.According to modern pharmacology analysis, these functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage class Chinese medicine have good anti-inflammatory analgesic, improve the effect of smooth muscle spasm, therefore can have co-therapy effect to primary dysmenorrhea and secondary dysmenorrhea.
Function and curing mainly: functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage, the suitable all types of dysmenorrheas (constitutional or secondary dysmenorrhea) that cure mainly.
Use the course for the treatment of: having dysmenorrhea sensation to start to use once every day, was a course for the treatment of with three days continuously.
Consumption and consumption: when dysmenorrhea is come, bring into use and can prove effective, be preferably in and feel just before going to bed front use every day, to second day 2 left and right in afternoon, must open plaster, to allow skin permeability.As skin is had to infringement, can be every one day with a plaster.Generally select to face and start evening to paste, first will extract with clean warm towel, to in navel, clean up gently, then by giving a bottle that 10 grams of unguentum are housed as an addition, open, with a cotton swab of giving as an addition dip in bottle dysmenorrhea unguentum a little, navel bosom and wall surrounding are filled to this unguentum, at this moment the release paper that takes out again a rectangle plaster is torn, by simultaneously erecting with overflow-proof ring and the cotton piece of the rectangle that is stained with plaster, be affixed on (necessarily by the perpendicular subsides of rectangle cream pad) on navel, allow " navel " (SHENQUE acupoint) aim at upper 1/3rd places that erect the cotton piece of rectangle.Necessarily remembering: morning will be forgotten scarcely after getting up and opens gently plaster one side, a little is put into navel and increases dose with cotton swab, to dip in unguentum in bottle again, because the unguentum of navel that put into evening before that day, skin by a night absorbs, and having arrived morning has not just had what yet.So must again insert unguentum in navel).
User must be in each rectangle plaster pasting on umbilicus, also must be again by perpendicular (the navel parallel aligned position approximately and before human body, lumbar vertebra position that is affixed on of a rectangle plaster with cotton piece, this is the MINGMEN acupoint on Chinese medicine acupuncture is learned), the lumbar vertebra place at soreness of waist position when also directly heavily fortified point is affixed on menstruation and comes.Difference is exactly needn't be at the first paste of lumbar vertebra, but is directly affixed on lumbar vertebra place and can plaster is perpendicular.
Points for attention: 1, this product is only for external application, forbid taking orally; 2, skin allergy person is cautious use of, and for skin injury position person, forbids.3, place the place that child does not reach; 4, because umbilical part unguentum has functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage effect, so anemia of pregnant woman's forbidding; If 5 force on after local skin there is pimple or serious pruritus, illustrate that patient, to this plaster allergy, should stop using immediately.6,, can not after having a bath, be affixed on immediately affected part, can after half an hour, paste again.
The present invention is used for the treatment of dysmenorrhea patient 200 examples and carries out clinical observation treatment.Wherein age those at least is 13 years old, the maximum 49 years old, and 27 years old mean age: wherein without sexual life person 72 examples, person's 128 examples that have sexual life: the course of disease 2 months~20 years.According to the type of dysmenorrhea, divide primary dysmenorrhea 72 examples, secondary dysmenorrhea 128 examples.According to pain degree, divide severe 86 examples, moderate 74 examples, slight 40 examples.This group case through gynecologial examination and/B ultrasonic makes a definite diagnosis, and gets rid of reproductive system organ mechanical injuries in pelvic cavity.
Efficacy assessment standard: the present invention is used for the treatment of dysmenorrhea disease, its criterion of therapeutical effect is formulated with reference to the < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > of national traditional chinese medical science administration issue, is divided into following three kinds:
Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.Heal in end: improvement is seen at pain end.
Therapeutic effect: after 2 courses for the treatment of, cure 88 examples, 107 examples that take a turn for the better, end is 5 examples more, total effective rate 97.5%.A course for the treatment of of light moderate patient external, Most patients transference cure, minority again external course for the treatment of transference cure.Severe pain is after 3 courses for the treatment of of patient's external, and some patients were transference cure, is cured, and most of patients is clearly better.For light moderate pain through patient, general paste once after obvious relieving dysmenorrhea degree just, paste after secondary just relieving dysmenorrhea substantially not bitterly or hypodynia.Severe pain after patient is using first course for the treatment of, the degree of Most patients relieving dysmenorrhea.
Compared with prior art, the invention has the beneficial effects as follows: the present invention draws through groping in a large number to sum up according to the treatment dysmenorrhea principle of functions dispelling wind and clearing away cold, removing dampness, dredge the meridian passage, by the Chinese medicine in compositions of the present invention, mutually there is synergism, there is quick elimination or relieving dysmenorrhea symptom, can replace existing market homogeneous groups compound completely.Simultaneously composition material of the present invention is easy to get, with low cost, preparation is simple, have no side effect, and can alleviate patient's the advantages such as financial burden.

Claims (3)

1. a treatment dysmenorrhea umbilical part external plaster compositions, is characterized in that: it has one for the crude drug of the following parts by weight of etiology and pathology and pharmacology: Radix Flemingiae Philippinensis 50-90 part, Rhizoma Drynariae 60-97 part, Radix Cynanchi Paniculati 50-95 part, Radix Gentianae Macrophyllae 70-130 part, Fructus Chaenomelis 50-90 part, Radix Angelicae Pubescentis 50-95 part, Herba speranskiae tuberculatae 60-94 part, Herba Lycopodii 80-130 part, Caulis Fissistigmatis 80-130 part, Folium Clerodendri Trichotomi 70-130 part, Herba Siegesbeckiae 90-150 part, Borneolum Syntheticum 5-30 part, azone 1-10 part.
2. a kind of dysmenorrhea umbilical part external plaster compositions for the treatment of according to claim 1, is characterized in that: 70 parts of Radix Flemingiae Philippinensis, 80 parts of Rhizoma Drynariae, 70 parts of Radix Cynanchi Paniculatis, 80 parts of Radix Gentianae Macrophyllae, 60 parts of Fructus Chaenomeliss, 70 parts of Radix Angelicae Pubescentiss, 75 parts of Herba speranskiae tuberculataes, 110 parts of Herba Lycopodiis, 90 parts of Caulis Fissistigmatiss, Folium Clerodendri Trichotomi 80 95 parts of Fen, Herba Siegesbeckiaes, 5 parts of Borneolum Syntheticums, 1 part of azone.
3. according to a kind of dysmenorrhea umbilical part external plaster compositions for the treatment of described in claim 1,2, it is characterized in that: it has a meticulous manufacture method:
1. except Borneolum Syntheticum, azone two tastes, other 11 kinds of Chinese medicines, according to parts by weight, after adding between the water soaking 1 hour of 5 times, then are added to the decocting of 6 times and boil 3 hours, filter, filtering residue.The decocting that adds again 6 times boils 3 hours, filters, filtering residue, merges secondary filtrate, continues to decoct to be concentrated into extractum (relative density is 1.03)
2. the extractum being condensed into is positioned under room temperature, adds 1 part of Borneolum Syntheticum and 1 part of medical chlorine ketone, stir into gently even one-tenth cream standby.
3. by machine or be manually coated in respectively every block length 10cm, on the special-purpose extractum plaster of rectangle of the cotton piece of wide 6cm, with standby.
4. separately again the extractum being condensed into is used respectively 10g bottle package encapsulation standby, or it is standby to make cone shape medicated core.
CN201410019742.9A 2014-01-06 2014-01-06 One treats dysmenorrhea external omphaloidean ointment Expired - Fee Related CN103720924B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181269A (en) * 1997-12-01 1998-05-13 董锡山 Pain relieving antiphlogistine and its prepn. method
CN101912572A (en) * 2010-07-30 2010-12-15 崔宝海 Multi-effect external plaster

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181269A (en) * 1997-12-01 1998-05-13 董锡山 Pain relieving antiphlogistine and its prepn. method
CN101912572A (en) * 2010-07-30 2010-12-15 崔宝海 Multi-effect external plaster

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"温经止痛散", 《医学文选》, no. 05, 30 October 1994 (1994-10-30), pages 40 *
韩树国: "内服外敷中药治疗风湿症1239例效果观察", 《承德医学院学报》, no. 03, 30 September 1998 (1998-09-30), pages 214 - 215 *

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