CN103705949B - The off-line sterilizing methods of the respiratory organ on a kind of surge tank - Google Patents
The off-line sterilizing methods of the respiratory organ on a kind of surge tank Download PDFInfo
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- CN103705949B CN103705949B CN201310726449.1A CN201310726449A CN103705949B CN 103705949 B CN103705949 B CN 103705949B CN 201310726449 A CN201310726449 A CN 201310726449A CN 103705949 B CN103705949 B CN 103705949B
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Abstract
The invention provides the off-line sterilizing methods of the respiratory organ on a kind of surge tank, first, remove respiratory organ and the combination of respiratory organ hands valve, the respiratory organ mouth on surge tank seals with vexed plate, and surge tank carries out washing and sterilizing automatically; Then, below respiratory organ hands valve, install a nondominant hand valve, respiratory organ hands valve is opened, and nondominant hand valve cuts out, and the entirety after the combination of respiratory organ, respiratory organ hands valve and nondominant hand valve is put into sterilizing cabinet sterilizing; After overall sterilizing after the combination of respiratory organ, respiratory organ hands valve and nondominant hand valve completes, under filling machine A level laminar flow, nondominant hand valve of dismantling, is then arranged on respiratory organ and the combination of respiratory organ hands valve on the respiratory organ mouth on surge tank.Method provided by the invention overcomes the deficiencies in the prior art, not only can realize the thorough sterilizing of respiratory organ, and simplify sterilizing program, save the time, improve production efficiency, reduce cost, can ensure aseptic requirement simultaneously.
Description
Technical field
The present invention relates to the off-line sterilizing methods of the respiratory organ on a kind of surge tank, belong to fill surge tank technical field.
Background technology
The sterilization method of the respiratory organ on fill surge tank is generally divided into online sterilizing and off-line sterilizing two kinds of modes.Online sterilizing can reduce the pollution that the personnel that may cause in artificial dismounting and the worry of installing and process involve in.But this surge tank can because whole tank body carries out online sterilizing under being in A level laminar flow, owing to can distribute a large amount of heats in environment in tank body sterilization process thereupon, the humiture of A level district local environment can be affected so to a certain extent, so likely can encourage the probability of microbial growth.And more pneumatic operated valve can be there is in A level district due to automatic control system, in the cylinder of valve, also certain compressed air can be discharged like this in the process of valve event, and these gases are often without degerming compressed air, so directly be released in A level region layer stream, just likely pollute the gnotobasis in A level district, and the continual release of compressed air, also can have influence on the stability of A level region layer stream, make air-flow become turbulent flow.The final like this filling environment that can have influence on medicine, medicine work it out also just can not ensure aseptic.
Although for the system of automatic on-line sterilizing, what also have does isothermal holding to surge tank, the air vent of the cylinder of pneumatic operated valve is drawn laminar region, or bacteria removing etc. means are done to the source of the gas of pneumatic operated valve, but how many whole processes still can have influence on the environment in A level district.And thing is more, the cleaning-sterilizing of whole equipment, environment is all very difficult, thus the mode of off-line sterilizing also praise highly by a lot of pharmaceutical factory.
The method of traditional off-line sterilizing is:
The first step: under A level laminar flow, closes manual diaphragm valve, and then remove respiratory organ and the combination of hands valve, sterilizing cabinet off-line sterilizing of taking away, the respiratory organ mouth on surge tank seals with vexed plate;
Second step: by pass-through box, the respiratory organ after sterilizing and hands valve combination transmission are come in, then respiratory organ is arranged on surge tank, now the filter element of respiratory organ together with the upper semisection of hands valve by sterilizing.And the lower semisection being in the hands valve of closed condition is contaminated in transmittance process;
3rd step: after respiratory organ installs, surge tank automatic on-line sterilizing again, can fall the lower semisection of the hands valve connect below respiratory organ like this to sterilizing.
Whole surge tank is removed off-line sterilizing; or the online sterilizing of surge tank; and the respiratory organ on surge tank removes off-line sterilizing; but whole surge tank and respiratory organ remove the method inconvenient operation of off-line sterilizing; surge tank is heavier; and transport and also need to carry out the protection to the mouth of pipe on surge tank in installation process, otherwise secondary pollution can be caused.If will separate as the respiratory organ on surge tank and its and do sterilizing, then respiratory organ removes off-line sterilizing, and surge tank carries out online sterilizing, surge tank does not have energy thoroughly sterilizing so often, and the respiratory organ after off-line sterilizing exists the problem of sterile transfer.
The method of traditional off-line sterilizing, except respiratory organ must off-line sterilizing, after importantly the online sterilizing of surge tank must wait respiratory organ and the sterilizing of hands valve combination off-line to complete, installs and just to carry out afterwards, just calculate overall sterilizing afterwards and complete.But cause production process to postpone like this, the hidden danger existed in addition is that the part that the diaphragm of diaphragm valve is held down cannot thoroughly sterilizing.
Summary of the invention
The technical problem to be solved in the present invention is the sterilizing program of the respiratory organ simplified on surge tank, reduces costs, and makes sterilization effect meet aseptic requirement.
In order to solve the problems of the technologies described above, technical scheme of the present invention is to provide the off-line sterilizing methods of the respiratory organ on a kind of surge tank, respiratory organ is located on the respiratory organ mouth on the surge tank of filling machine, is provided with respiratory organ hands valve, it is characterized in that below respiratory organ: the method is made up of following 3 steps:
Step 1: remove respiratory organ and the combination of respiratory organ hands valve, the respiratory organ mouth on surge tank seals with vexed plate, and then surge tank carries out online sterilizing automatically;
Step 2: install a nondominant hand valve below respiratory organ hands valve, respiratory organ hands valve is opened, nondominant hand valve cuts out, and then the entirety after the combination of respiratory organ, respiratory organ hands valve and nondominant hand valve is put into sterilizing cabinet sterilizing;
Step 3: after the overall sterilizing after the combination of respiratory organ, respiratory organ hands valve and nondominant hand valve completes, under filling machine A level laminar flow, nondominant hand valve of dismantling, is then arranged on respiratory organ and the combination of respiratory organ hands valve on the respiratory organ mouth on surge tank.
Preferably, described nondominant hand valve is in closed condition all the time.
Preferably, in described step 1, the online sterilizing of surge tank, being the surge tank to removing after respiratory organ and the combination of respiratory organ hands valve, being circulated the sterilizing carried out by surge tank steam inside.
After the off-line sterilizing methods of the respiratory organ on surge tank provided by the invention carries out sterilizing, surge tank, respiratory organ, the respiratory organ hands valve comprised under respiratory organ is all in aseptic condition, then can carry out production fill.
Method provided by the invention overcomes the deficiencies in the prior art, not only can realize the thorough sterilizing of respiratory organ, and simplify sterilizing program, save the time, improve production efficiency, reduce cost, can ensure aseptic requirement simultaneously.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the first step in embodiment;
Fig. 2 is the schematic diagram of second step in embodiment;
Fig. 3 is the schematic diagram of the 3rd step in embodiment.
Detailed description of the invention
For making the present invention become apparent, hereby with a preferred embodiment, and accompanying drawing is coordinated to be described in detail below.
Fig. 1 ~ Fig. 3 is the off-line sterilizing methods process schematic of the respiratory organ on surge tank provided by the invention, respiratory organ is contained on the respiratory organ mouth on the surge tank of filling machine, respiratory organ hands valve is housed below respiratory organ, and the off-line sterilizing methods of the respiratory organ on described surge tank is made up of following 3 steps:
The first step: composition graphs 1, remove respiratory organ and respiratory organ hands valve combination 1, the respiratory organ mouth on surge tank 2 seals with vexed plate, and then surge tank 2 can carry out online sterilizing automatically.The online sterilizing of surge tank, what refer to is exactly that surge tank is removed after respiratory organ, and to be circulated the online sterilizing carried out by steam inside, this operation is carried out in bottling department, but row's mouth of its sterilizing is located at other regions, such as between dosing or between wash bottle etc.
Second step: composition graphs 2, install a nondominant hand valve 4 below the respiratory organ hands valve 3 below respiratory organ, respiratory organ hands valve 3 is opened, and nondominant hand valve 4 cuts out, and then entirety is put into sterilizing cabinet 5 sterilizing.
3rd step: composition graphs 3, after respiratory organ sterilizing completes, filling machine A level laminar flow 6 times, nondominant hand valve 4 (this valve is cut out all the time) of dismantling, is then arranged on respiratory organ and respiratory organ hands valve combination 1 on the respiratory organ mouth of surge tank 2.Now, surge tank, respiratory organ, the whole respiratory organ hands valve comprised under respiratory organ is all in aseptic condition, then can carry out production fill.
By the off-line sterilizing methods of the respiratory organ on surge tank provided by the invention, not only can realize the thorough sterilizing of respiratory organ, and after surge tank also need not wait respiratory organ sterilizing to complete, then carry out online sterilizing together, like this from the production time, can relatively save time.As long as after the namely online sterilizing of system terminates, respiratory organ passes aseptic docking, wholely can enter production bottling condition, improves production efficiency.
Claims (2)
1. the off-line sterilizing methods of the respiratory organ on a surge tank, respiratory organ is located on the respiratory organ mouth on the surge tank (2) of filling machine, be provided with respiratory organ hands valve (3) below respiratory organ, it is characterized in that: the method is made up of following 3 steps:
Step 1: remove respiratory organ and respiratory organ hands valve combination (1), the respiratory organ mouth on surge tank (2) seals with vexed plate, and then surge tank (2) carries out online sterilizing automatically;
The online sterilizing of surge tank (2) is the surge tank (2) to removing after respiratory organ and respiratory organ hands valve combination (1), to be circulated the sterilizing carried out by surge tank (2) steam inside;
Step 2: install a nondominant hand valve (4) below respiratory organ hands valve (3), respiratory organ hands valve (3) is opened, nondominant hand valve (4) cuts out, and then the entirety after the combination of respiratory organ, respiratory organ hands valve (3) and nondominant hand valve (4) is put into sterilizing cabinet (5) sterilizing;
Step 3: after the overall sterilizing after the combination of respiratory organ, respiratory organ hands valve (3) and nondominant hand valve (4) completes, under filling machine A level laminar flow, to dismantle nondominant hand valve (4), then respiratory organ and respiratory organ hands valve combination (1) are arranged on the respiratory organ mouth on surge tank (2).
2. the off-line sterilizing methods of the respiratory organ on a kind of surge tank as claimed in claim 1, is characterized in that: described nondominant hand valve (4) is in closed condition all the time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310726449.1A CN103705949B (en) | 2013-12-25 | 2013-12-25 | The off-line sterilizing methods of the respiratory organ on a kind of surge tank |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310726449.1A CN103705949B (en) | 2013-12-25 | 2013-12-25 | The off-line sterilizing methods of the respiratory organ on a kind of surge tank |
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| CN103705949A CN103705949A (en) | 2014-04-09 |
| CN103705949B true CN103705949B (en) | 2016-02-03 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007167546A (en) * | 2005-12-26 | 2007-07-05 | Ishikawajima Harima Heavy Ind Co Ltd | Method and device for gas-sterilizing narrow tube part |
| CN101915362A (en) * | 2010-08-26 | 2010-12-15 | 上海创洁科技有限公司 | Small-capacity injection material transport system |
| CN203173190U (en) * | 2013-04-16 | 2013-09-04 | 楚天科技股份有限公司 | Medicine liquid buffer tank having on-line cleaning sterilizing function |
| CN103318824A (en) * | 2013-06-04 | 2013-09-25 | 上海东富龙科技股份有限公司 | Constant pressure device |
-
2013
- 2013-12-25 CN CN201310726449.1A patent/CN103705949B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007167546A (en) * | 2005-12-26 | 2007-07-05 | Ishikawajima Harima Heavy Ind Co Ltd | Method and device for gas-sterilizing narrow tube part |
| CN101915362A (en) * | 2010-08-26 | 2010-12-15 | 上海创洁科技有限公司 | Small-capacity injection material transport system |
| CN203173190U (en) * | 2013-04-16 | 2013-09-04 | 楚天科技股份有限公司 | Medicine liquid buffer tank having on-line cleaning sterilizing function |
| CN103318824A (en) * | 2013-06-04 | 2013-09-25 | 上海东富龙科技股份有限公司 | Constant pressure device |
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| CN103705949A (en) | 2014-04-09 |
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