CN103705701B - A kind of Chinese medicine preparation treating knee joint osseous arthritis - Google Patents
A kind of Chinese medicine preparation treating knee joint osseous arthritis Download PDFInfo
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- CN103705701B CN103705701B CN201310755472.3A CN201310755472A CN103705701B CN 103705701 B CN103705701 B CN 103705701B CN 201310755472 A CN201310755472 A CN 201310755472A CN 103705701 B CN103705701 B CN 103705701B
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Abstract
The invention discloses a kind of Chinese medicine preparation treating knee joint osseous arthritis. The main pathogenesis of knee joint osseous arthritis is insufficiency of kidney-YANG, deficiency of spleen-YANG and kidneyYANG. The cause of disease is how not enough by natural endowment, will lose the day after tomorrow and supports, or internal injury of being overworked for a very long period, prolonged illness lack of proper care cause kidney qi, deficiency of spleen-QI, then caused by deficiency of spleen-YANG and kidneyYANG. The present invention selects have the liver and the kidney tonifying, relaxing muscles and tendons and activating QI and blood in the collateral, blood circulation promoting and blood stasis dispelling, the Chinese medicine Radix hemerocalis plicatae of expelling wind and removing dampness, Radix Paeoniae Alba, Radix Berchemiae floribundae, Radix seu caulis wrightiae pubescentis, Caulis et folium gaultheriae yunnanensis, Herba Lysimachiae Insignis, Folium Vaccinii Fragilis, Radix Aconiti Heterotrichi, Radix seu Caulis Schisandrae Sinensis, Herba Spilanthis callimorphae, decocting becomes decoction, evident in efficacy through clinical trial, and have no adverse reaction.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation treating knee joint osseous arthritis.
Background technology
Knee joint osseous arthritis is relatively common clinically in osteoarthritis, and main manifestations is arthralgia, swelling and dysfunction, is more common in old people. In recent years, sickness rate, in the trend risen year by year, have impact on the quality of life of patient, and current doctor trained in Western medicine is but without the medicine of specially good effect. Adopting Chinese traditional treatment to obtain good clinical effectiveness in recent years, Chinese traditional treatment is started with from pathogenesis, use have the liver and the kidney tonifying, blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness effect Chinese medicine dialectical execute doctor, reach treating both the principal and secondary aspects of a disease, effect is notable, and relapse rate is low. This condition of disease is enough played macroscopic view opsonic action by traditional Chinese medical science Orally-administered decoction, dialectical divides and rules, has effectively contained and taken the negative effect that Western medicine is likely to bring.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treating knee joint osseous arthritis. The main pathogenesis of knee joint osseous arthritis is insufficiency of kidney-YANG, deficiency of spleen-YANG and kidneyYANG. The cause of disease is how not enough by natural endowment, will lose the day after tomorrow and supports, or internal injury of being overworked for a very long period, prolonged illness lack of proper care cause kidney qi, deficiency of spleen-QI, then caused by deficiency of spleen-YANG and kidneyYANG. Osteoarthritis belongs to impediment syndrome category, i.e. " rheumatism involving the bone ". Control with the liver and the kidney tonifying, relaxing muscles and tendons and activating QI and blood in the collateral, blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness.
It is an object of the invention to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment knee joint osseous arthritis is made up of the Chinese medicine of following weight portion: Radix hemerocalis plicatae 9-15 part, Radix Paeoniae Alba 6-12 part, Radix Berchemiae floribundae 30-50 part, Radix seu caulis wrightiae pubescentis 30-40 part, Caulis et folium gaultheriae yunnanensis 9-15 part, Herba Lysimachiae Insignis 3-9 part, Folium Vaccinii Fragilis 9-15 part, Radix Aconiti Heterotrichi 0.05-0.1 part, Radix seu Caulis Schisandrae Sinensis 9-15 part, Herba Spilanthis callimorphae's 3-9 part.
Preferably, Radix hemerocalis plicatae 12 parts, Radix Paeoniae Alba 10 parts, Radix Berchemiae floribundae 40 parts, Radix seu caulis wrightiae pubescentis 35 parts, Caulis et folium gaultheriae yunnanensis 12 parts, Herba Lysimachiae Insignis 6 parts, Folium Vaccinii Fragilis 12 parts, Radix Aconiti Heterotrichi 0.07 part, Radix seu Caulis Schisandrae Sinensis 12 parts, Herba Spilanthis callimorphae 6 parts.
Above-mentioned Chinese medicine decocting is made decoction by preparation method.
Fang Zhong: Radix hemerocalis plicatae is nourished blood suppressing the hyperactive liver, inducing diuresis to remove edema; Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receive antiperspirant; Radix Berchemiae floribundae, Radix seu caulis wrightiae pubescentis wind-damp dispelling, eliminating stasis to stop pain, the meridian dredging; Caulis et folium gaultheriae yunnanensis, Herba Lysimachiae Insignis expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral; Folium Vaccinii Fragilis, Radix Aconiti Heterotrichi relaxing muscles and tendons to promote blood circulation, promoting blood circulation and stopping pain; Radix seu Caulis Schisandrae Sinensis, Herba Spilanthis callimorphae's promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.
Clinical data
1, physical data 130 example patient all meets knee joint osseous arthritis diagnostic criteria, is randomly divided into treatment group and each 65 examples of matched group. Treatment group: male 28 examples, female 37 example, 23��75 years old age, average 47.6 years old, the course of disease 5 months��8 years. Matched group: male 26 examples, female 39 example, the age is 24��74 years old, average 48.3 years old, the course of disease 5 months��8 years. Two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.
2, diagnostic criteria knee articulation is dumb, can not be movable immediately after sitting, station of a specified duration or rest, and rear sense activity is walked about and relaxed one's muscles to feel ankylosis freely. The visible knee joint mild swelling of health check-up, movable joint has slight rattler, the grating of creaking, and can touch tuberosity or streak thing, touch to have on time and ache inside knee joint, atrophy that knee joint peripheral muscle is slight. Lab testing: knee joint hyperosteogeny is shown in x-ray inspection, and joint space narrows, subchondral bone has hardening and blister cavities to be formed, and epiphysis deformation in late period, articular surface is uneven.
3, Therapeutic Method treatment group takes Chinese medicine preparation of the present invention, weighs Radix hemerocalis plicatae 12g, Radix Paeoniae Alba 10g, Radix Berchemiae floribundae 40g, Radix seu caulis wrightiae pubescentis 35g, Caulis et folium gaultheriae yunnanensis 12g, Herba Lysimachiae Insignis 6g, Folium Vaccinii Fragilis 12g, Radix Aconiti Heterotrichi 0.07g, Radix seu Caulis Schisandrae Sinensis 12g, Herba Spilanthis callimorphae 6g. Decocting becomes decoction, and potion, divided and sooner or later took for 2 times every day. Matched group takes diclofenac sodium enteric-coated tablets treatment, each 50mg, every day 2 times. Two groups of courses for the treatment of are 3 months.
4, criterion of therapeutical effect recovery from illness: knee joint swelling, pain disappears, and functional rehabilitation is normal, follows up a case by regular visits to 1 year and does not recur. Effective: knee joint swelling, pain disappear, and functional rehabilitation is normal, follows up a case by regular visits in 1 year and has recurrence, often in climate change or overwork dull pain occurs. Effective: the gonalgia, swelling are become slightly from severe, function does not recover normal completely. Invalid: the unchanged person of symptom, sign.
5, therapeutic outcome two groups treatment two courses for the treatment of after comparitive study, treatment group 65 example, wherein cure 20 examples (30.8%), effective 23 examples (35.4%), effective 15 examples (23.1%), invalid 7 examples (10.8%), total effective rate 89.2%; Matched group 65 example, wherein cures 4 examples (6.2%), effective 19 examples (29.2%), effective 11 examples (16.9%), invalid 31 examples (47.7%), total effective rate 52.3%. Two groups are compared, and treatment group cure rate, total effective rate are substantially better than matched group, have comparability (P < 0.01).
Detailed description of the invention
Embodiment one: weigh Radix hemerocalis plicatae 12g, Radix Paeoniae Alba 10g, Radix Berchemiae floribundae 40g, Radix seu caulis wrightiae pubescentis 35g, Caulis et folium gaultheriae yunnanensis 12g, Herba Lysimachiae Insignis 6g, Folium Vaccinii Fragilis 12g, Radix Aconiti Heterotrichi 0.07g, Radix seu Caulis Schisandrae Sinensis 12g, Herba Spilanthis callimorphae 6g, becomes decoction by above-mentioned Chinese medicine decocting.
Embodiment two: weigh Radix hemerocalis plicatae 15g, Radix Paeoniae Alba 6g, Radix Berchemiae floribundae 50g, Radix seu caulis wrightiae pubescentis 30g, Caulis et folium gaultheriae yunnanensis 15g, Herba Lysimachiae Insignis 3g, Folium Vaccinii Fragilis 15g, Radix Aconiti Heterotrichi 0.05g, Radix seu Caulis Schisandrae Sinensis 15g, Herba Spilanthis callimorphae 3g, becomes decoction by above-mentioned Chinese medicine decocting.
Embodiment three: weigh Radix hemerocalis plicatae 9g, Radix Paeoniae Alba 12g, Radix Berchemiae floribundae 30g, Radix seu caulis wrightiae pubescentis 40g, Caulis et folium gaultheriae yunnanensis 9g, Herba Lysimachiae Insignis 9g, Folium Vaccinii Fragilis 9g, Radix Aconiti Heterotrichi 0.1g, Radix seu Caulis Schisandrae Sinensis 9g, Herba Spilanthis callimorphae 9g, becomes decoction by above-mentioned Chinese medicine decocting.
Claims (1)
1. the Chinese medicine preparation treating knee joint osseous arthritis, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight: Radix hemerocalis plicatae 12g, Radix Paeoniae Alba 10g, Radix Berchemiae floribundae 40g, Radix seu caulis wrightiae pubescentis 35g, Caulis et folium gaultheriae yunnanensis 12g, Herba Lysimachiae Insignis 6g, Folium Vaccinii Fragilis 12g, Radix Aconiti Heterotrichi 0.07g, Radix seu Caulis Schisandrae Sinensis 12g, Herba Spilanthis callimorphae 6g, above-mentioned Chinese medicine decocting is become decoction.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1618448A (en) * | 2003-11-19 | 2005-05-25 | 北京双鹤药业股份有限公司 | Medicine composition for treating osseous arthritis, and its prepn. method |
| CN1813991A (en) * | 2005-11-24 | 2006-08-09 | 蓝子花 | Damp-repellent pain-relieving medicinal liquor of wuye |
| CN102579947A (en) * | 2012-02-15 | 2012-07-18 | 韦嵩 | Chinese medicinal composition and preparation method thereof |
| CN103463338A (en) * | 2013-08-23 | 2013-12-25 | 国长锋 | Externally applied Traditional Chinese medicine preparation for treating gouty arthritis |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1618448A (en) * | 2003-11-19 | 2005-05-25 | 北京双鹤药业股份有限公司 | Medicine composition for treating osseous arthritis, and its prepn. method |
| CN1813991A (en) * | 2005-11-24 | 2006-08-09 | 蓝子花 | Damp-repellent pain-relieving medicinal liquor of wuye |
| CN102579947A (en) * | 2012-02-15 | 2012-07-18 | 韦嵩 | Chinese medicinal composition and preparation method thereof |
| CN103463338A (en) * | 2013-08-23 | 2013-12-25 | 国长锋 | Externally applied Traditional Chinese medicine preparation for treating gouty arthritis |
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Effective date of registration: 20170503 Address after: Nanjing road 226100 Jiangsu Sijia town of Haimen city of Nantong province No. 78 Patentee after: HAIMEN RUITAI TEXTILE TECHNOLOGY Co.,Ltd. Address before: Hospital of traditional Chinese medicine, Huangdao District, Hainan Island Road, Shandong, 158, Qingdao, China Patentee before: Ji Zhongyi |
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