CN103656504A - Traditional Chinese medicine composition for treating depression and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating depression and preparation method thereof Download PDF

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CN103656504A
CN103656504A CN201310659662.5A CN201310659662A CN103656504A CN 103656504 A CN103656504 A CN 103656504A CN 201310659662 A CN201310659662 A CN 201310659662A CN 103656504 A CN103656504 A CN 103656504A
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chinese medicine
depression
medicine composition
cure
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CN103656504B (en
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王洪涛
刘艳辉
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Shandong Zhongda Pharmaceutical Co Ltd
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Shandong Zhongda Pharmaceutical Co Ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for treating depression and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. The composition comprises, by weight, 2 to 12 parts of cassia seed, 5 to 15 parts of root of large-flowered skullcap, 5 to 15 parts of dried orange peel, 3 to 15 parts of fried curcuma tuber, 2 to 10 parts of Poria cocos, 3 to 10 parts of fried inner membrane of chicken gizzard, 1 to 9 parts of fried barley, 3 to 10 parts of Chinese thorowax root, 2 to 15 parts of Chinese angelica, 3 to 10 parts of Sichuan lovage rhizome, 3 to 12 parts of Gentiana Scabra Bunge, 2 to 9 parts of red sage root, 1 to 10 parts of nutgrass galingale rhizome, 2 to 12 parts of virgate wormwood herb, 1 to 8 parts of finger citron, 2 to 9 parts of Bigai, 2 to 8 parts of licorice, 2 to 9 parts of Rujin, 1 to 8 parts of unprocessed rehmannia root and 2 to 8 parts of turmeric. The invention has the following beneficial effects: the traditional Chinese medicine composition for treating depression prepared from the above-mentioned raw materials by using the preparation method has fast action, exerts no toxic and side effects on a human body, can substantially mitigate symptoms of a patient with depression and enables the patient to live a normal life as ordinary people.

Description

The Chinese medicine composition of Cure of depression and preparation method
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition of Cure of depression, also relate to the preparation method of said composition.
Background technology
Depression claims again depressive disorder, and the remarkable and lasting mental state of take is low is main clinical characteristics, is the main Types of mood disorders.Clinical visible mental state is low unbecoming with its situation, and the downhearted of emotion can be from depressed to extremely grieved, and the depression of feeling oneself inferior is even pessimistic and worldweary, can have suicidal attempt or behavior; Even occur numb; Some cases have obvious anxiety and mobility intense; Can there is the psychotic symptoms such as hallucination, vain hope in severe patient.Even each outbreak continued at least 2 all above, elder's several years, majority of cases has the tendency of outbreak repeatedly, and the great majority that at every turn show effect can be alleviated, and part can have residual symptoms or transfer to chronic.
So far, the cause of disease of depression is also unclear, but certainly, biological, the psychological and all many factors of social environment have participated in the pathogenic process of depression.Biological factor relates generally to the aspects such as heredity, neural biochemistry, neuroendocrine, neuranagenesis; Easily suffering from quality with depression psychology in close relations is premorbid personality feature, as depressed makings.Manhood meets with irritable life events, is the important trigger condition that causes occurring having the paralepsy of clinical meaning.Yet above these factors are not to work separately, emphasize at present reciprocal action between nature-nurture or stressors and thisly interactively occur that time point has important impact in depression generating process.In modern society, fast pace ground work and life, heavy work and life stress, make people suffer from very much depression, therefore need to invent a kind of instant effect and the medicine of Cure of depression that human body is had no side effect.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of instant effect and the Chinese medicine composition of Cure of depression that human body is had no side effect;
The present invention also provides the preparation method of above-mentioned Chinese medicine composition.
Chinese medicine composition of the present invention comprises the component of following portions by weight:
A Chinese medicine composition for Cure of depression, said composition comprises the component of following portions by weight:
Figure BDA0000432214070000011
Figure BDA0000432214070000021
Preferably, the Chinese medicine composition of above-mentioned a kind of Cure of depression, comprises the component of following portions by weight:
Figure BDA0000432214070000022
Preferred, a kind of Chinese medicine composition of Cure of depression, comprises the component of following portions by weight:
Figure BDA0000432214070000023
Figure BDA0000432214070000031
Preferred, a kind of Chinese medicine composition of Cure of depression, comprises the component of following portions by weight:
Figure BDA0000432214070000032
The preparation method of the Chinese medicine composition of Cure of depression, comprises following step:
To in above-mentioned raw water, decoct 2 times, 1-2 hour for the first time, 0.8-1.2 hour for the second time, collecting decoction, filters, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.18-1.25, adding ethanol, to make it contain alcohol amount be 60-70%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.
The above-mentioned time decocting is for the first time 1.5 hours.
The above-mentioned time decocting is for the second time 1 hour.
The clear paste that when preferably, filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2.
Semen Cassiae has clearing away heat to improve acuity of vision, the effect of loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Return liver, kidney, large intestine channel.The effect that has fat-reducing.Control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.
Radix Scutellariae is a kind of plant of Labiatae Scutellaria, belongs to half kind kind of semi-wild, herbaceos perennial.The root of Radix Scutellariae is a kind of medical herbs, bitter in the mouth, cold in nature, energy heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are used in fungal culture miscellaneous bacteria and infect special severity by the strong feature of broad-spectrum antibacterial action, and fine by Radix Scutellariae extracting solution effect, it is that agricultural disease is prevented and treated optimal a herb.
Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.Abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in turbid damp resistance.Phlegm-damp is stopped up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Fry Radix Curcumae acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.
Poria is commonly called as Poria, Song Ling, Poria, and for colonizing in the fungi plant on pinaster root, shape is as Rhizoma Dioscoreae esculentae, crust pitchy, the inside white or pink.Its protozoa is the dry sclerotia of On Polyporaceae Poria, and multiparasitization is in the root of Pinus massoniana Lamb or Pinus densiflora.Originate in the ground such as Yunnan, Anhui, Hubei, Henan, Sichuan.Ancients claim that Poria is " god medicine " at 4 o'clock, because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, all diseases that wets can be brought into play its unique effects.Poria sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, anticancer function relieves internal heat.The property of medicine is gentle, dampness removing and do not hinder healthy energy.Take in right amount the good merchantable brand of taking good care of that can be used as spring and summer wet season.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.Contained pachymic acid has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc.The gastrointestinal smooth muscle that can relax, the effect such as gastric acid secretion inhibiting, prevents hepatic necrosis, antibacterial.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Endothelium Corneum Gigeriae Galli (parched) is got fresh Endothelium Corneum Gigeriae Galli parch and is formed, effect invigorating the stomach and promoting digestion, arresting seminal emission.Be widely used in clinically accumulation of food in the stomach and intes tine due to indigestion, infantile malnutrition, the enuresis, seminal emission, can be used for again the treatment of the diseases such as cholelithiasis, lithangiuria.
Fructus Hordei Vulgaris (parched) is a kind of traditional refreshment drink of the widespread among the people such as China, Japan, Korea S, and Fructus Hordei Vulgaris parch is become to sallow, before eating, only need within 2~3 minutes, just can leach strong scented tea by brewed in hot water.Fructus Hordei Vulgaris tea is will be after Fructus Hordei Vulgaris parch through boiling, boil and obtain, newss have one dense wheat fragrant, drinking Fructus Hordei Vulgaris tea not only can whet the appetite, can also be aid digestion, the effect of losing weight in addition.
Radix Bupleuri clearind deficient heat Chinese medicine, for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus come off, menoxenia.
Radix Angelicae Sinensis effect is all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong original name rhizome of chuanxiong Qiong.A Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Main Cultivation in Sichuan, the ground such as Yunnan, Guizhou, Guangxi, Hubei.The pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, nearly says the functions such as pungent loose, the resolving depression of its residence, sensible, pain relieving.The pungent temperature rise of this product is loose, and all hyperactivity of YANG due to deficiency of YIN and excessive rising of liver-YANG person should not apply; Menorrhagia, anemia of pregnant woman also avoid use.
Radix Gentianae is bitter, cold.Enter liver, gallbladder meridian.Be mainly used in treating eliminating pathogen in the liver gallbladder excess-fire, except damp-heat in lower-JIAO.Treating the liver is through intenseness of heat, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, the disease such as scrotum swells and ache, pudendum pruritus due to damp pathogen.
Radix Salviae Miltiorrhizae has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, Arisaema balansae Engl. etc.For dicotyledon Labiatae, dry root and rhizome.Main product in Anhui, the ground such as Henan, Shaanxi.Effect: Radix Salviae Miltiorrhizae has GUIXIN, Liver Channel.Can stasis-dispelling and pain-killing, promoting blood flow to regulate menstruation, lowering blood-fat and reducing weight, relieving restlessness clears away heart-fire.
Rhizoma Cyperi slightly warm in nature, acrid in the mouth.Cure mainly the resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Herba Artemisiae Scopariae property is bitter, pungent, is slightly cold.Return spleen, stomach, liver, gallbladder meridian.Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly: jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc.Pharmaceutical research has function of gallbladder promoting, and liver function protecting is antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, the effects such as coronary dilating.
Fructus Citri Sarcodactylis property is pungent, bitter, sweet, warm, nontoxic; Enter liver, spleen, stomach three warps, have activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the more kinds of medicinal functions of stomach function regulating.
Radix Glycyrrhizae has antiinflammatory, antiviral, and protecting liver and detoxication and strengthen the effects such as immunologic function.
The Radix Rehmanniae is also Radix Rehmanniae, is the tuber of scrophulariaceae rehmannia glutinosa plant, and the fresh or dry tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae, is used as medicine.Main product is in China Henan, Hebei, the Inner Mongol and northeast.There is cultivation most areas.Excavate autumn, using fresh herb or dry sliced raw using.Radix Rehmanniae Preparata is that Radix Rehmanniae is mixed steaming to inside and outside local darkish complexion, glossy through adding yellow wine, or directly steaming to black profit forms.Cutting sheet uses.The effect that Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid.
Rhizoma Curcumae Longae is the rhizome of zingiberaceous plant Rhizoma Curcumae Longae, Rhizoma Curcumae Longae another name has tripod perfume, Dioscorea zingiberensis, hair Rhizoma Curcumae Longae, Huang Siyu, the effect of Rhizoma Curcumae Longae is removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia, the effect of Rhizoma Curcumae Longae is to control all cards of stagnation of QI and blood, born of the same parents' abdomen hypochondriac pain, dysmenorrhes, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, rheumatic arthralgia, traumatic injury, carbuncle, and Rhizoma Curcumae Longae medication taboo is blood deficiency without qi depression to blood stasis and anemia of pregnant woman is careful takes Rhizoma Curcumae Longae.
Beneficial effect of the present invention is, adopts above-mentioned formula and method to prepare resulting Cure of depression Chinese medicine composition, and instant effect and human body is had no side effect can obviously alleviate the symptom of patients with depression, makes it spend ordinary people's orthobiosis.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Figure BDA0000432214070000061
To in above-mentioned raw water, decoct 2 times, 1.5 hours for the first time, 1 hour for the second time, collecting decoction, filter, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2, adding ethanol, to make it contain alcohol amount be 65%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.
The present invention has carried out clinical experiment, and in taking Chinese medicine composition 50 male volunteers of 30 days of Cure of depression of the present invention, wherein 49 patients with depression symptoms obviously alleviate, and effective percentage is 98%;
Embodiment 2
Figure BDA0000432214070000062
To in above-mentioned raw water, decoct 2 times, 1 hour for the first time, 0.8 hour for the second time, collecting decoction, filter, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2, adding ethanol, to make it contain alcohol amount be 65%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.
Embodiment 3
Figure BDA0000432214070000072
To in above-mentioned raw water, decoct 2 times, 2 hours for the first time, 0.8 hour for the second time, collecting decoction, filter, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2, adding ethanol, to make it contain alcohol amount be 65%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.
Embodiment 4
Figure BDA0000432214070000073
Figure BDA0000432214070000081
To in above-mentioned raw water, decoct 2 times, 1 hour for the first time, 1.2 hours for the second time, collecting decoction, filter, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2, adding ethanol, to make it contain alcohol amount be 65%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.

Claims (8)

1. a Chinese medicine composition for Cure of depression, is characterized in that, described compositions comprises the component of following portions by weight:
Figure FDA0000432214060000011
2. the Chinese medicine composition of a kind of Cure of depression as claimed in claim 1, is characterized in that, described compositions comprises the component of following portions by weight:
Figure FDA0000432214060000012
3. the Chinese medicine composition of a kind of Cure of depression as claimed in claim 1, is characterized in that, described compositions comprises the component of following portions by weight:
Figure FDA0000432214060000021
4. the Chinese medicine composition of a kind of Cure of depression as claimed in claim 1, is characterized in that, described compositions comprises the component of following portions by weight:
Figure FDA0000432214060000022
5. the preparation method of the Chinese medicine composition of a kind of Cure of depression as claimed in claim 1, is characterized in that, described method comprises following step:
To in above-mentioned raw water, decoct 2 times, 1-2 hour for the first time, 0.8-1.2 hour for the second time, collecting decoction, filters, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.18-1.25, adding ethanol, to make it contain alcohol amount be 60-70%, get supernatant and reclaim ethanol, be concentrated into paste, after conventional treatment and get final product.
6. the preparation method of the Chinese medicine composition of a kind of Cure of depression as claimed in claim 5, is characterized in that, the described time decocting is for the first time 1.5 hours.
7. the preparation method of the Chinese medicine composition of a kind of Cure of depression as claimed in claim 5, is characterized in that, the described time decocting is for the second time 1 hour.
8. the preparation method of the Chinese medicine composition of a kind of Cure of depression as claimed in claim 5, is characterized in that, the clear paste that when filtrate is concentrated into temperature and is 70 ℃, relative density is 1.2.
CN201310659662.5A 2013-12-06 2013-12-06 The Chinese medicine composition of Cure of depression and preparation method Expired - Fee Related CN103656504B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383440A (en) * 2014-11-11 2015-03-04 李桂亮 Orally-taken pharmaceutical preparation for treating tristimania
CN104707120A (en) * 2015-02-17 2015-06-17 湖南科技学院 Traditional Chinese medicine composition for eliminating dampness and phlegm and soothing liver and regulating qi as well as preparation method of traditional Chinese medicine composition
CN106075314A (en) * 2016-08-16 2016-11-09 梁相斌 A kind of Chinese medicine composition alleviating depression and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1129569A (en) * 1995-02-23 1996-08-28 颜建邦 Medicament for removing blood stasis and resolving depression
CN1308959A (en) * 2001-01-12 2001-08-22 王东桥 Medicine 'Yishenjieyu' for treating mental diseases (psychosis)
CN103349756A (en) * 2013-07-24 2013-10-16 赵世明 Traditional Chinese medicine composition for treating depression

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1129569A (en) * 1995-02-23 1996-08-28 颜建邦 Medicament for removing blood stasis and resolving depression
CN1308959A (en) * 2001-01-12 2001-08-22 王东桥 Medicine 'Yishenjieyu' for treating mental diseases (psychosis)
CN103349756A (en) * 2013-07-24 2013-10-16 赵世明 Traditional Chinese medicine composition for treating depression

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383440A (en) * 2014-11-11 2015-03-04 李桂亮 Orally-taken pharmaceutical preparation for treating tristimania
CN104707120A (en) * 2015-02-17 2015-06-17 湖南科技学院 Traditional Chinese medicine composition for eliminating dampness and phlegm and soothing liver and regulating qi as well as preparation method of traditional Chinese medicine composition
CN104707120B (en) * 2015-02-17 2018-04-03 湖南科技学院 A kind of eliminating dampness and eliminating phlegm, dispersing stagnated hepatoqi Chinese medicine composition and preparation method thereof
CN106075314A (en) * 2016-08-16 2016-11-09 梁相斌 A kind of Chinese medicine composition alleviating depression and preparation method thereof

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