CN103656203B - One treats hypertension medication and preparation method thereof - Google Patents
One treats hypertension medication and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to one and treat hypertension medication and preparation method thereof, belong to medical art.The raw material that it comprises following weight portion is made: Rhomotoxine 10-20, armillaria mellea powder 940-1000, sunflower plate 15-20, Herba Taxilli 15-20, Rhizoma Polygonati 12-20, Spica Prunellae 12-20, Radix Puerariae 12-20, Semen Ziziphi Spinosae 12-20, Flos Chrysanthemi 6-10, Radix Achyranthis Bidentatae 12-20, Fructus Crataegi 10-20, Radix Polygoni Multiflori Preparata 10-20, Concha Haliotidis 12-20, Fructus Ligustri Lucidi 12-20.Under " blood pressure lowering of taking advantage of a situation, natural blood fat reducing " theory is followed in this invention, by the mode of pure Chinese medicine comprehensively regulating, treating both the principal and secondary aspects of a disease, while the steady blood pressure lowering of the gesture complying with human body, pure natural herbaceous plant is utilized to help natural fat eliminating, herbal nature gos deep into the bottom of heart, the vital organs of the human body of human body are nursed one's health comprehensively, comprehensively restoring cardio, brain, kidney, blood vessel, recover human body and regulate blood pressure ability, effecting a radical cure hypertension from root, finally realize away from hypertension, hyperlipidemia, helping hyperpietic away from taking medicine all the life.
Description
Technical field
The present invention relates to one and treat hypertension medication and preparation method thereof, belong to medical art.
Background technology
Hypertension, hyperlipidemia all belong to metabolism syndrome.Hypertension shows human vas, and hyperlipidemia shows systemic blood.The two does not fall for a long time, all can impel into atherosclerotic formation, causes complication.According to statistics, China's Hypertensive Population has had 200,000,000 people, and also constantly increases with the speed of 1,000 ten thousand every year.The Hypertensive Population mean age is only 54 years old, has lived 20 years lesser than China's average life.
Traditional method, when treating hypertension, hyperlipidemia, mainly controls blood pressure blood fat by Western medicine, can not truly prophylaxis of hypertension hyperlipidemia complication.Hypertension, hyperlipemic patients are when withdrawal, and blood pressure blood fat increases at once.The complication such as myocardial infarction, cerebral infarction, hypertensive heart disease can be caused in the face of hypertension, hyperlipemia, allow patient find it hard to tell about one's suffering, Long-term taking medicine can only be forced to, seem that everything imply that hypertension, hyperlipemia patient is doomed to take medicine all the life.Prolonged administration of drugs, allows patient produce heavy dependence to hypertension and hyperlipemia medicine.In addition, because hypertension and hyperlipemia Western medicine has very large toxic and side effects, Long-term taking medicine causes in drug residue body, cannot metabolism excrete, also can cause serious injury to organs such as human body Liver and kidney, the reason that Here it is why " a lot of patients' blood is steady, and body constitution is but worse and worse ".In brief, conventional medicament hypertension and hyperlipemia method is in fact be exactly exchange blood pressure blood fat for " life-span " to decline.
Summary of the invention
In order to overcome above-mentioned defect, one is the object of the present invention is to provide to treat hypertension medication and preparation method thereof.
To achieve these goals, the present invention adopts following technical scheme:
One treats hypertension medication, and the raw material that it comprises following weight portion is made:
Rhomotoxine 10-20 armillaria mellea powder 940-1000 sunflower plate 15-20
Herba Taxilli 15-20 Rhizoma Polygonati 12-20 Spica Prunellae 12-20
Radix Puerariae 12-20 Semen Ziziphi Spinosae 12-20 Flos Chrysanthemi 6-10
Radix Achyranthis Bidentatae 12-20 Fructus Crataegi 10-20 Radix Polygoni Multiflori Preparata 10-20
Concha Haliotidis 12-20 Fructus Ligustri Lucidi 12-20.
The weight portion of above-mentioned raw materials composition is preferably:
Rhomotoxine 20 armillaria mellea powder 940 sunflower plate 15 Herba Taxilli 15 Rhizoma Polygonati 12 Spica Prunellae 12 Radix Puerariae 12 Semen Ziziphi Spinosae 12 Flos Chrysanthemi 6 Radix Achyranthis Bidentatae 12 Fructus Crataegi 10 Radix Polygoni Multiflori Preparata 10
Concha Haliotidis 12 Fructus Ligustri Lucidi 12.
A kind of process for producing granula for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol weight such as adding carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, dextrin puts in trough type mixing machine; Add extractum soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, take out granule after drying, pack and get final product.
A kind of capsule preparation method thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add starch and dried cream powder is put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine and mix, filling, plastic-aluminum, packaging and get final product.
A kind of method for preparing tablet thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, starch and dried cream powder and put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine, add magnesium stearate, mixing, tabletting, plastic-aluminum, packaging and get final product.
Beneficial effect of the present invention:
For current national medicining condition, under " blood pressure lowering of taking advantage of a situation, natural blood fat reducing " theory is followed in this invention, by the mode of pure Chinese medicine comprehensively regulating, treating both the principal and secondary aspects of a disease, while the steady blood pressure lowering of the gesture complying with human body, pure natural herbaceous plant is utilized to help natural fat eliminating, herbal nature gos deep into the bottom of heart, the vital organs of the human body of human body are nursed one's health comprehensively, comprehensively restoring cardio, brain, kidney, blood vessel, recover human body and regulate blood pressure ability, effect a radical cure hypertension from root, final realization, away from hypertension, hyperlipidemia, helps hyperpietic away from taking medicine all the life.
Prescription compatibility of medicines is analyzed:
Rhomotoxine: [pharmacological action] is (1) to the pharmacological action of cardio-cerebrovascular: hypotensive effect, arrhythmia, protective effect to neonatal hypoxia ischemia, anticoagulant and antithrombotic.(2) to the effect of maincenter: sedation, antiepileptic action, effect to central norepinephrine (NA).(3) antiasthmatic effect.(4) on sciatic impact.(5) on the impact of immunologic function.[application prospect] is expected to be developed as treatment hypertension, treatment headache, treatment epilepsy, and treatment neurasthenia, treats dizzy optimal medicine.
Armillaria mellea powder: armillaria mellea is the symbiosis host of gastrodia elata.In the natural environment of the growth course of Rhizoma Gastrodiae, its mycelia invades in Gastrodia Elata Stem Tuber cells of superficial layer, with the form of mycelia or mycelia secretions for Rhizoma Gastrodiae provides nutrient substance to originate.Rhizoma Gastrodiae does not have the nutrition organs of plant, and unrooted, why can growth promoter without leaf, just by means of the nutriment that armillaria mellea provides, is able to Growth and anthesis result.Have left armillaria mellea, the seed of Rhizoma Gastrodiae can not be sprouted, and atrophy is also degenerated by tuber.Pharmacological evaluation proves, close ring mattress culture has the physiologically active same with Rhizoma Gastrodiae, has similar curative effect both clinical trial proves.Clinical treatment hyperlipidemia patient, has reduction hypercholesterolemia, and falls the effect of hypertriglyceridemia.To reducing blood pressure, improving symptom also has certain effect.
Sunflower plate: [nature and flavor] sweet in the mouth; [return through] cold in nature returns Liver Channel [function cures mainly] heat clearing away; Suppressing the hyperactive liver; Pain relieving; Hemostasis.Main hypertension; Headache; Dizzy; Tinnitus; Abdominal pain; Dysmenorrhea; Metrorrhagia; Skin ulcer rash [effect pharmacological action] has obvious nerve depressor response to cardiovascular system; Have double influence to heart, extractum dialysis solution both containing the composition to Cardiac depression, also had the composition of heart tonifying.
Herba Taxilli: [nature and flavor] are bitter; Sweet; Property is put down.[return through] enters liver, kidney channel.[function cures mainly] invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling; Antiabortive.Main soreness of waist and knee joint; Muscles and bones flaccidity is weak; Limbs are hemiplegia; Rheumatic arthralgia; Head is wrong dizzy; Frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement; Hypertension.
" pharmacognosy ": control arteriosclerotic hypertension." Liaoning economic plants will ": control stasis nephritis, difficult menstruation, spitting of blood, scrofula, all diseases of heart and early stage pneumonopathy.
Rhizoma Polygonati: [nature and flavor] are sweet; Flat; [return through] spleen; Lung; Kidney channel; [effect] boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying; [effect classification] tonic; [curing mainly] deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease
Spica Prunellae: nature and flavor: bitter, acrid, cold; Enter liver, gallbladder meridian.Efficacy effect: (1) liver heat removing and eyesight improving, for liver-heat conjunctival congestion and swelling pain, and the headache of excessive rising of liver-YANG, dizzy (as hypertension), 2. blood pressure lowering: control hypertension, hyperlipidemia, high blood viscosity and hyperglycemia.3. mass dissipating and swelling eliminating: control scrofula, goiter, acute mastitis swell and ache." modern Practical Chinese medicinal ": be diuretic, effective to gonorrhea, hysteropathy; And can hypertension be controlled, can blood pressure drops be made.
Radix Puerariae: there is refrigerant reducing internal heat, whetting the appetite, diuresis is relieved the effect of alcohol, reduced blood pressure specially good effect.The puerarin extracted from Radix Puerariae has coronary artery dilator and arteriocerebral effect, significantly can increase the blood supply amount of ischemic tissue, have B1 to be subject to health body blocking effect, the heart that can obviously slow down is overworked, reduces myocardial oxygen consumption, myocardial ischemia can be alleviated, limit and reduce myocardial infarct size, Antitachycardiac agents, cholesterol and blood viscosity can be reduced, anticoagulant, improves microcirculation.Ten several amino acids containing human body needs in Amylum Puerariae Radicis and ten various trace elements, wherein the content of calcium, zinc, phosphorus is the highest, and richness " selenium " element contained by Amylum Puerariae Radicis, has effect of certain cancer-resisting.Amylum Puerariae Radicis also has: promoting the production of body fluid to quench thirst, the effect of antibacterial and detoxicating, to coronary heart disease, the throat pain caused catching a cold, aphtha of the mouth and tongue, the child dysentery that relieves inflammation or internal heat has good therapeutical effect, also can to cure the wound excessive cold invading middle-JIAO(the spleen and stomach) wind headache, control chest and diaphragm dysphoria with smothery sensation to go mad, hemostasis dysentery, logical small intestinal, evacuation of pus removing blood stasis, sharp defecation, to relieve the effect of alcohol, control weakness of the spleen and stomach and to have loose bowels certain effect.
Semen Ziziphi Spinosae: effect: nourishing the liver, mind calming, calms the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility; Pharmacological action: 1. calm, syngignoscism: 2. stable effect: 3. analgesia, cooling, hypotensive effect;
Flos Chrysanthemi: efficacy effect aspect, property is sweet, be slightly cold, there is loose wind heat, suppressing the hyperactive liver improving eyesight, disappear and cough effect of pain relieving, be used for the treatment of the disease Be very effective such as headache is dizzy, conjunctival congestion and swelling pain, anemopyretic cold, cough, also there is effect of refreshment, modern pharmacological research shows, Flos Chrysanthemi has treatment coronary heart disease, reduces blood pressure, prevents hyperlipidemia, antibacterial, antiviral, antiinflammatory, anti-ageing multiple pharmacologically active of waiting for a long time.
Radix Achyranthis Bidentatae: Gui Jing: liver; Kidney channel; Effect: dispel-wind drug; Blood circulation and stasis-eliminating medicine.Invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome." Amplification on Materia Medica addendum ": all medicines can be drawn descending." Bencao Jingshu ": Radix Achyranthis Bidentatae, walks and can mend, and property is apt to descending, therefore enters Liver and kidney.Main tonifying liver then muscle is relaxed, descending, manages knee joint, and promoting the circulation of blood then pain stops.By vim and vigour, still cloud can lead to qi stagnation hemagglutination also.The detailed property of medicine, gas is used as numbness.Fire of getting mildewed in warm conditions is rotten, the shrivelled disease of blood also, blood and living, pain oneself stop.Enter liver promoting the circulation of blood, blood stored in the liver, kidney storing essence, high invigorating the liver and kidney, then hemapodium and essence is full, all cards are from recover.Blood then the moon water from logical, blood agglomeration is from loose.Cure mainly: soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.
Fructus Crataegi: containing multivitamin, Crataegolic acid, citric acid, malic acid, saccharide, calcium, ferrum, phosphorus, etc. multiple nutrients material, the lipolytic enzyme contained in Fructus Crataegi can also promote the food digestion of fats, and Fructus Crataegi can also promote gastric secretion and increase the functions such as gastric enzyme element.Have simultaneously removing food stagnancy spend stagnant, convergence dysentery relieving, activating blood circulation to dissipate blood stasis, significant blood vessel dilating and blood pressure lowering etc. effect.Often eat the function that Fructus Crataegi also has strong cardiac muscle, arrhythmia, adjustment blood pressure and cholesterol.
Fructus Crataegi can also effectively reduce serum cholesterol and triglyceride, can effectively preventing atherosclerosis, has cardiotonic.The patient of hypertension and hyperlipidemia and coronary heart disease, gets Fructus Crataegi 15-30 gram every day, has extraordinary auxiliary therapeutic action.
Radix Polygoni Multiflori Preparata: [nature and flavor] are bitter; Sweet; Puckery; Slightly warm in nature; [return through] liver; Kidney channel; [effect] system is used: enrich and benefit essence and blood; Raw use: removing toxic substances, preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation; [effect classification] tonic; Dispel-wind drug; Promote hemopoietic function; Strengthen immunologic function; Blood fat reducing and atherosclerosis; Protect the liver; Improve body's immunity, slow down aging, affects endocrine function, the effects such as loosening bowel to relieve constipation.The material base of Radix Polygoni Multiflori efficacy effect is mainly the compositions such as phospholipid, Anthraquinones, glucose glycoside.[curing mainly] blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.
Concha Haliotidis: salty in the mouth; Cold in nature; Gui Jing: Liver Channel.Function: calming liver and clearing heat; Improving eyesight removing nebula.Cure mainly: have a headache dizzy; Cataract; Blurring of vision; Optic atrohic blindness nyctalopia.Pharmacological action has: have heat clearing away, calmness, blood pressure lowering, sympatheticomimetic effect.
Fructus Ligustri Lucidi: sweet in the mouth, hardship, cool in nature; Gui Jing: liver, kidney channel; Effect: tonifying liver kidney yin, crow must improving eyesight, and modern medicine study thinks that Fructus Ligustri Lucidi can suppress the effect of helicobacter pylori to treat gastropathy, also has the treatment suppressing purine abnormal metabolism for gout and hyperuricemia.Cure mainly: for the hepatic and renal YIN deficiency, soreness of waist tinnitus, early whitening of beard and hair; Unseeing, poor vision; Fever due to yin deficiency, gastropathy and gout and and hyperuricemia.
All medicines play nourishing the liver and kidney altogether above, the merit of suppressing the hyperactive liver and subsiding YANG.The vital organs of the human body can be nursed one's health comprehensively, recover body fat metabolism and Liver and kidney metabolism, and recover self-regulating function and blood supply oxygen delivery capacity again, prevent blood vessel die back, soften, dredging vascellum, thrombus dissolving, purify the blood rubbish, and row's endotoxin, improves blood viscosity, reduce small artery resistance, prevention of arterial is atherosis, can realize taking advantage of a situation, steady blood pressure lowering, eliminates future trouble and to get rid of illness root.Be usually used in deficiency of the liver and kindey, excessive rising of liver-YANG, dizziness and headache, insomnia tinnitus, soreness of the waist and knees duke or princess under an emperor person.
Detailed description of the invention
Describe the present invention below in conjunction with embodiment:
Embodiment 1
One treats hypertension medication, and the raw material that it comprises following weight portion is made:
Rhomotoxine 20 armillaria mellea powder 940 sunflower plate 15 Herba Taxilli 15 Rhizoma Polygonati 12 Spica Prunellae 12 Radix Puerariae 12 Semen Ziziphi Spinosae 12 Flos Chrysanthemi 6 Radix Achyranthis Bidentatae 12 Fructus Crataegi 10 Radix Polygoni Multiflori Preparata 10
Concha Haliotidis 12 Fructus Ligustri Lucidi 12.
A kind of process for producing granula for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol weight such as adding carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, dextrin puts in trough type mixing machine; Add extractum soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, take out granule after drying, pack and get final product.
A kind of capsule preparation method thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add starch and dried cream powder is put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine and mix, filling, plastic-aluminum, packaging and get final product.
A kind of method for preparing tablet thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, starch and dried cream powder and put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine, add magnesium stearate, mixing, tabletting, plastic-aluminum, packaging and get final product.
Embodiment 2
One treats hypertension medication, and the raw material that it comprises following weight portion is made:
Rhomotoxine 10 armillaria mellea powder 1000 sunflower plate 20 Herba Taxilli 20 Rhizoma Polygonati 20 Spica Prunellae 20 Radix Puerariae 20 Semen Ziziphi Spinosae 20 Flos Chrysanthemi 10 Radix Achyranthis Bidentatae 20 Fructus Crataegi 20 Radix Polygoni Multiflori Preparata 20
Concha Haliotidis 20 Fructus Ligustri Lucidi 20.
A kind of process for producing granula for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol weight such as adding carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, dextrin puts in trough type mixing machine; Add extractum soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, take out granule after drying, pack and get final product.
A kind of capsule preparation method thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add starch and dried cream powder is put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine and mix, filling, plastic-aluminum, packaging and get final product.
A kind of method for preparing tablet thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, starch and dried cream powder and put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine, add magnesium stearate, mixing, tabletting, plastic-aluminum, packaging and get final product.
Embodiment 3
One treats hypertension medication, and the raw material that it comprises following weight portion is made:
Rhomotoxine 15 armillaria mellea powder 960 sunflower plate 18 Herba Taxilli 18 Rhizoma Polygonati 15 Spica Prunellae 16 Radix Puerariae 17 Semen Ziziphi Spinosae 15 Flos Chrysanthemi 8 Radix Achyranthis Bidentatae 15 Fructus Crataegi 15 Radix Polygoni Multiflori Preparata 15
Concha Haliotidis 15 Fructus Ligustri Lucidi 15.
A kind of process for producing granula for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol weight such as adding carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, dextrin puts in trough type mixing machine; Add extractum soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, take out granule after drying, pack and get final product.
A kind of capsule preparation method thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add starch and dried cream powder is put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine and mix, filling, plastic-aluminum, packaging and get final product.
A kind of method for preparing tablet thereof for the treatment of hypertension medication:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot; use soak by water secondary, the vapour that adds water out for the first time decocts, and boils; be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and decocting liquid filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C. pulverize after drying, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, starch and dried cream powder and put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule. put in two-dimensional mixing machine, add magnesium stearate, mixing, tabletting, plastic-aluminum, packaging and get final product.
Claims (4)
1. treat a hypertension medication, it is characterized in that its raw material of Chinese medicine is made up of the component of following weight portion:
Rhomotoxine 20 armillaria mellea powder 940 sunflower plate 15 Herba Taxilli 15 Rhizoma Polygonati 12 Spica Prunellae 12 Radix Puerariae 12 Semen Ziziphi Spinosae 12 Flos Chrysanthemi 6 Radix Achyranthis Bidentatae 12 Fructus Crataegi 10 Radix Polygoni Multiflori Preparata 10 Concha Haliotidis 12 Fructus Ligustri Lucidi 12.
2. a process for producing granula for treatment hypertension according to claim 1 medication, is characterized in that:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot, use soak by water secondary, the vapour that adds water out for the first time decocts, and boils, be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and filtrate filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol weight such as adding carries out alcohol and analyses, and fully stirs, leave standstill and make precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the extractum that relative density is 1.38, temperature is 80 DEG C, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, dextrin puts in trough type mixing machine; Add extractum soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, take out granule after drying, pack and get final product.
3. a capsule preparation method thereof for treatment hypertension according to claim 1 medication, is characterized in that:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot, use soak by water secondary, the vapour that adds water out for the first time decocts, and boils, be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and filtrate filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, and leaves standstill and makes precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C; Pulverize after drying, obtain dried cream powder, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add starch and dried cream powder is put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule; Put in two-dimensional mixing machine and mix, filling, plastic-aluminum, packaging and get final product.
4. a method for preparing tablet thereof for treatment hypertension according to claim 1 medication, is characterized in that:
The sunflower plate of above-mentioned weight portion, Herba Taxilli, Rhizoma Polygonati, Spica Prunellae, Radix Puerariae, Semen Ziziphi Spinosae, Flos Chrysanthemi, Radix Achyranthis Bidentatae, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Concha Haliotidis, Fructus Ligustri Lucidi are put in multifunctional extracting pot, use soak by water secondary, the vapour that adds water out for the first time decocts, and boils, be incubated 2 hours, decocting liquid filters; Second time adds water boil, is incubated 1 hour, and filtrate filters, filtrate is incorporated in basin, above-mentioned decocting liquid is squeezed into high-order drug storage tank by pump, concentrates, release medicinal liquid, the ethanol adding equivalent carries out alcohol and analyses, and fully stirs, and leaves standstill and makes precipitation in 24 hours, get supernatant, filter, carry out recovery ethanol, be evaporated to the thick paste that relative density is 1.38, temperature is 80 DEG C; Pulverize after drying, obtain dried cream powder, for subsequent use;
Deserve to be called Rhomotoxine, the armillaria mellea powder of stating weight portion, and add Icing Sugar, starch and dried cream powder and put in trough type mixing machine; Add Diluted Alcohol soft material, granulate with oscillating granulator, pour pallet into and send in heat-circulation oven, after drying, take out granule; Put in two-dimensional mixing machine, add magnesium stearate, mixing, tabletting, plastic-aluminum, packaging and get final product.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102423421A (en) * | 2011-12-06 | 2012-04-25 | 陈中元 | Medicine for treating hypertension |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102423421A (en) * | 2011-12-06 | 2012-04-25 | 陈中元 | Medicine for treating hypertension |
Non-Patent Citations (2)
| Title |
|---|
| 向日葵盘降压作用与原理探讨;天津新港卫生院等;《新医药学杂志》;19771231(第4期);第1段 * |
| 高血压病的中医理论及防治规律探讨;詹文涛;《云南中医杂志》;19831231(第1期);第21、23页 * |
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